Details for: FZD4

Gene ID: 8322

Symbol: FZD4

Ensembl ID: ENSG00000174804

Description: frizzled class receptor 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 124.4654
    Cell Significance Index: -19.3600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 42.0670
    Cell Significance Index: -17.0900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 39.4389
    Cell Significance Index: -18.6200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 17.9211
    Cell Significance Index: -17.1100
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 13.3741
    Cell Significance Index: 58.2200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.1788
    Cell Significance Index: -17.9000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.9036
    Cell Significance Index: -19.3500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 3.1710
    Cell Significance Index: 39.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.8113
    Cell Significance Index: 263.3000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.2695
    Cell Significance Index: 66.1300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.1159
    Cell Significance Index: 21.7800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.9623
    Cell Significance Index: 13.8400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.8922
    Cell Significance Index: 5.5200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.6769
    Cell Significance Index: 7.6900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6731
    Cell Significance Index: 18.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4392
    Cell Significance Index: 83.5800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.4170
    Cell Significance Index: 5.3400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.3816
    Cell Significance Index: 5.4800
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.3608
    Cell Significance Index: 3.4300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.2980
    Cell Significance Index: 3.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2744
    Cell Significance Index: 55.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2352
    Cell Significance Index: 212.4000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2249
    Cell Significance Index: 22.2500
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.2052
    Cell Significance Index: 1.6200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1163
    Cell Significance Index: 23.0800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1153
    Cell Significance Index: 18.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1022
    Cell Significance Index: 11.9100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0506
    Cell Significance Index: 2.3600
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.0434
    Cell Significance Index: 0.4500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0420
    Cell Significance Index: 26.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0370
    Cell Significance Index: 1.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0181
    Cell Significance Index: 12.5500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0176
    Cell Significance Index: 1.9100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0073
    Cell Significance Index: 0.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0037
    Cell Significance Index: 2.3800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0006
    Cell Significance Index: -0.8900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0043
    Cell Significance Index: -8.0800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0051
    Cell Significance Index: -0.3100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0086
    Cell Significance Index: -3.8000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0087
    Cell Significance Index: -6.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0091
    Cell Significance Index: -1.5500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0101
    Cell Significance Index: -18.6600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0119
    Cell Significance Index: -8.8300
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0149
    Cell Significance Index: -0.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0151
    Cell Significance Index: -20.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0163
    Cell Significance Index: -5.8400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0200
    Cell Significance Index: -0.5000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0234
    Cell Significance Index: -1.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0238
    Cell Significance Index: -3.2700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0245
    Cell Significance Index: -13.7900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0246
    Cell Significance Index: -3.1500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0257
    Cell Significance Index: -19.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0264
    Cell Significance Index: -14.4400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0273
    Cell Significance Index: -12.4000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0412
    Cell Significance Index: -7.4400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0524
    Cell Significance Index: -11.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0530
    Cell Significance Index: -15.2600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0542
    Cell Significance Index: -3.7500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0612
    Cell Significance Index: -0.4100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0702
    Cell Significance Index: -1.5200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0706
    Cell Significance Index: -7.2100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0758
    Cell Significance Index: -5.3600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1046
    Cell Significance Index: -8.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1070
    Cell Significance Index: -12.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1101
    Cell Significance Index: -13.5400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1323
    Cell Significance Index: -7.9400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1330
    Cell Significance Index: -4.2600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1414
    Cell Significance Index: -16.1400
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1471
    Cell Significance Index: -1.2500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1472
    Cell Significance Index: -19.0200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1828
    Cell Significance Index: -2.9000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1884
    Cell Significance Index: -19.6200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1888
    Cell Significance Index: -9.5400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2188
    Cell Significance Index: -17.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2305
    Cell Significance Index: -15.5000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2330
    Cell Significance Index: -5.9900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2331
    Cell Significance Index: -6.1300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2392
    Cell Significance Index: -10.5800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2459
    Cell Significance Index: -5.1000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2502
    Cell Significance Index: -18.6500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2578
    Cell Significance Index: -4.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2674
    Cell Significance Index: -15.0100
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: -0.2742
    Cell Significance Index: -2.3200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2763
    Cell Significance Index: -7.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3083
    Cell Significance Index: -18.9500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3092
    Cell Significance Index: -14.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3129
    Cell Significance Index: -11.8500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3206
    Cell Significance Index: -6.7100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3542
    Cell Significance Index: -12.3100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3608
    Cell Significance Index: -2.1800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3658
    Cell Significance Index: -19.0000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3737
    Cell Significance Index: -19.6200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3796
    Cell Significance Index: -5.7200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3833
    Cell Significance Index: -12.5500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3988
    Cell Significance Index: -13.9700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3997
    Cell Significance Index: -12.7300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.4095
    Cell Significance Index: -3.4400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4098
    Cell Significance Index: -17.8200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4258
    Cell Significance Index: -10.3900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4899
    Cell Significance Index: -13.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FZD4 is a transmembrane receptor that belongs to the Frizzled family of receptors, characterized by the presence of a seven-transmembrane domain and a cytoplasmic domain. It is highly expressed in various tissues, including the central nervous system, epithelial tissues, and endothelial cells. FZD4 has been shown to interact with Wnt proteins, which are secreted signaling molecules that regulate various cellular processes. The interaction between FZD4 and Wnt proteins triggers a series of signaling events that lead to the activation of the canonical Wnt signaling pathway. **Pathways and Functions** FZD4 is involved in various signaling pathways, including: 1. **Canonical Wnt Signaling Pathway**: FZD4 mediates Wnt signals that bind to its co-receptors, LRP5/6, triggering a series of downstream signaling events that lead to the regulation of gene expression, cell fate determination, and tissue development. 2. **Non-Canonical Wnt Signaling Pathway**: FZD4 also interacts with Wnt proteins to activate the non-canonical Wnt signaling pathway, which regulates cell migration, differentiation, and survival. 3. **Wnt5a-Dependent Internalization of FZD4**: FZD4 can be internalized by Wnt5a, leading to the regulation of its activity and the modulation of Wnt signaling. FZD4 plays a critical role in various cellular processes, including: 1. **Cell Proliferation and Differentiation**: FZD4 regulates cell proliferation and differentiation in various tissues, including the central nervous system and epithelial tissues. 2. **Cell Migration and Invasion**: FZD4 is involved in the regulation of cell migration and invasion, which is critical for tumor metastasis. 3. **Tissue Development and Homeostasis**: FZD4 plays a role in the regulation of tissue development and homeostasis, including the development of the central nervous system and epithelial tissues. **Clinical Significance** FZD4 has been implicated in various diseases, including: 1. **Cancer**: FZD4 is overexpressed in several types of cancer, including colorectal, breast, and lung cancer, and is associated with poor prognosis. 2. **Neurological Disorders**: FZD4 has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 3. **Cardiovascular Diseases**: FZD4 has been shown to play a role in the regulation of cardiovascular development and function, and is associated with cardiovascular diseases, including atherosclerosis and hypertension. In conclusion, FZD4 is a critical component of the Wnt signaling pathway, which regulates various cellular processes, including cell proliferation, differentiation, migration, and survival. Its dysregulation has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular diseases. Further studies are needed to fully understand the role of FZD4 in human disease and to develop therapeutic strategies to target this receptor.

Genular Protein ID: 1033016945

Symbol: FZD4_HUMAN

Name: Frizzled-4

UniProtKB Accession Codes:

Q9ULV1 A8K9Q3 Q14C97 Q6S9E4

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 EvolutionaryTrace 1 GO 47 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 8 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10544037

Title: Molecular cloning and characterization of human frizzled-4 on chromosome 11q14-q21.

PubMed ID: 10544037

DOI: 10.1006/bbrc.1999.1612

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9707618

Title: A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

PubMed ID: 9707618

DOI: 10.1073/pnas.95.17.10164

PubMed ID: 22575959

Title: ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

PubMed ID: 22575959

DOI: 10.1038/nature11019

PubMed ID: 24496449

Title: Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling.

PubMed ID: 24496449

DOI: 10.1242/jcs.140871

PubMed ID: 30135577

Title: Crystal structure of the Frizzled 4 receptor in a ligand-free state.

PubMed ID: 30135577

DOI: 10.1038/s41586-018-0447-x

PubMed ID: 12172548

Title: Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy.

PubMed ID: 12172548

DOI: 10.1038/ng957

PubMed ID: 14507768

Title: Frizzled 4 gene (FZD4) mutations in patients with familial exudative vitreoretinopathy with variable expressivity.

PubMed ID: 14507768

DOI: 10.1136/bjo.87.10.1291

PubMed ID: 15488808

Title: Novel mutation in FZD4 gene in a Japanese pedigree with familial exudative vitreoretinopathy.

PubMed ID: 15488808

DOI: 10.1016/j.ajo.2004.05.001

PubMed ID: 15035989

Title: Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

PubMed ID: 15035989

DOI: 10.1016/s0092-8674(04)00216-8

PubMed ID: 15223780

Title: Spectrum and frequency of FZD4 mutations in familial exudative vitreoretinopathy.

PubMed ID: 15223780

DOI: 10.1167/iovs.03-1044

PubMed ID: 15370539

Title: Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R).

PubMed ID: 15370539

DOI: 10.1080/13816810490514270

PubMed ID: 15733276

Title: Genetic variants of frizzled-4 gene in familial exudative vitreoretinopathy and advanced retinopathy of prematurity.

PubMed ID: 15733276

DOI: 10.1111/j.1399-0004.2005.00408.x

PubMed ID: 15981244

Title: Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes.

PubMed ID: 15981244

DOI: 10.1002/humu.20191

PubMed ID: 17093393

Title: Identification of novel FZD4 mutations in Indian patients with familial exudative vitreoretinopathy.

PubMed ID: 17093393

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17955262

Title: Moderate reduction of Norrin signaling activity associated with the causative missense mutations identified in patients with familial exudative vitreoretinopathy.

PubMed ID: 17955262

DOI: 10.1007/s00439-007-0438-8

PubMed ID: 19324841

Title: Clinical and molecular evaluation of probands and family members with familial exudative vitreoretinopathy.

PubMed ID: 19324841

DOI: 10.1167/iovs.08-3320

PubMed ID: 19172507

Title: Phenotypic overlap of familial exudative vitreoretinopathy (FEVR) with persistent fetal vasculature (PFV) caused by FZD4 mutations in two distinct pedigrees.

PubMed ID: 19172507

DOI: 10.1080/13816810802464312

PubMed ID: 20340138

Title: Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP.

PubMed ID: 20340138

DOI: 10.1002/humu.21250

PubMed ID: 20141357

Title: Severe retinopathy of prematurity associated with FZD4 mutations.

PubMed ID: 20141357

DOI: 10.3109/13816810903479834

Sequence Information:

  • Length: 537
  • Mass: 59881
  • Checksum: E0A83ECEC560A381
  • Sequence:
    • MAWRGAGPSV PGAPGGVGLS LGLLLQLLLL LGPARGFGDE EERRCDPIRI SMCQNLGYNV 
TKMPNLVGHE LQTDAELQLT TFTPLIQYGC SSQLQFFLCS VYVPMCTEKI NIPIGPCGGM 
CLSVKRRCEP VLKEFGFAWP ESLNCSKFPP QNDHNHMCME GPGDEEVPLP HKTPIQPGEE 
CHSVGTNSDQ YIWVKRSLNC VLKCGYDAGL YSRSAKEFTD IWMAVWASLC FISTAFTVLT 
FLIDSSRFSY PERPIIFLSM CYNIYSIAYI VRLTVGRERI SCDFEEAAEP VLIQEGLKNT 
GCAIIFLLMY FFGMASSIWW VILTLTWFLA AGLKWGHEAI EMHSSYFHIA AWAIPAVKTI 
VILIMRLVDA DELTGLCYVG NQNLDALTGF VVAPLFTYLV IGTLFIAAGL VALFKIRSNL 
QKDGTKTDKL ERLMVKIGVF SVLYTVPATC VIACYFYEIS NWALFRYSAD DSNMAVEMLK 
IFMSLLVGIT SGMWIWSAKT LHTWQKCSNR LVNSGKVKRE KRGNGWVKPG KGSETVV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.