Details for: PKP4

Gene ID: 8502

Symbol: PKP4

Ensembl ID: ENSG00000144283

Description: plakophilin 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 420.1350
    Cell Significance Index: -65.3500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 260.9964
    Cell Significance Index: -66.2000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 152.1917
    Cell Significance Index: -62.7000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 138.5576
    Cell Significance Index: -56.2900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 58.9583
    Cell Significance Index: -56.2900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 54.7059
    Cell Significance Index: -67.4500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 25.9254
    Cell Significance Index: -56.7400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.1817
    Cell Significance Index: -67.8000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 4.3532
    Cell Significance Index: 93.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 4.1284
    Cell Significance Index: 182.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 4.0582
    Cell Significance Index: 153.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.0368
    Cell Significance Index: 226.5300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.6312
    Cell Significance Index: 2306.2100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 3.5376
    Cell Significance Index: 50.8800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.5156
    Cell Significance Index: 6619.5200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 3.4398
    Cell Significance Index: 98.1600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.2301
    Cell Significance Index: 90.2700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 3.1582
    Cell Significance Index: 626.7500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.0499
    Cell Significance Index: 1093.9400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.8660
    Cell Significance Index: 574.9100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.8279
    Cell Significance Index: 190.1500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.5820
    Cell Significance Index: 22.9200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.7552
    Cell Significance Index: 1213.9400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.7013
    Cell Significance Index: 168.3000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4951
    Cell Significance Index: 243.1600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.4361
    Cell Significance Index: 99.3200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.2932
    Cell Significance Index: 67.3600
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.0860
    Cell Significance Index: 6.7000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9985
    Cell Significance Index: 76.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9242
    Cell Significance Index: 43.0900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9148
    Cell Significance Index: 112.4900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.8239
    Cell Significance Index: 20.6000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7970
    Cell Significance Index: 86.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7735
    Cell Significance Index: 422.4200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7691
    Cell Significance Index: 138.6400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6854
    Cell Significance Index: 42.1300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.6512
    Cell Significance Index: 11.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.5893
    Cell Significance Index: 801.2400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.5374
    Cell Significance Index: 991.1100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4994
    Cell Significance Index: 10.8200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.4966
    Cell Significance Index: 764.4300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4745
    Cell Significance Index: 28.4900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4297
    Cell Significance Index: 387.9800
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.4089
    Cell Significance Index: 4.2400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2647
    Cell Significance Index: 12.4400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2574
    Cell Significance Index: 7.4200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1925
    Cell Significance Index: 85.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1744
    Cell Significance Index: 7.9100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1470
    Cell Significance Index: 107.8100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1423
    Cell Significance Index: 27.0800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.1413
    Cell Significance Index: 2.3800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0987
    Cell Significance Index: 44.7800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0429
    Cell Significance Index: 1.0300
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.0301
    Cell Significance Index: 0.3900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0227
    Cell Significance Index: -3.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0428
    Cell Significance Index: -31.6900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0551
    Cell Significance Index: -34.4000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0791
    Cell Significance Index: -4.1100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0819
    Cell Significance Index: -61.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0833
    Cell Significance Index: -47.0000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1213
    Cell Significance Index: -20.7100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1788
    Cell Significance Index: -1.0800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2024
    Cell Significance Index: -27.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2028
    Cell Significance Index: -23.6300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2057
    Cell Significance Index: -59.2000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2282
    Cell Significance Index: -8.0200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2374
    Cell Significance Index: -50.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2941
    Cell Significance Index: -30.0500
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.3070
    Cell Significance Index: -4.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3167
    Cell Significance Index: -40.9100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3327
    Cell Significance Index: -34.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3333
    Cell Significance Index: -42.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4297
    Cell Significance Index: -49.2300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4297
    Cell Significance Index: -27.0800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4398
    Cell Significance Index: -9.6300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4638
    Cell Significance Index: -36.7300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5166
    Cell Significance Index: -38.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5198
    Cell Significance Index: -61.3000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5226
    Cell Significance Index: -59.6600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5408
    Cell Significance Index: -14.7200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5562
    Cell Significance Index: -34.1000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5752
    Cell Significance Index: -40.6800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5834
    Cell Significance Index: -12.4300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5951
    Cell Significance Index: -12.3500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6025
    Cell Significance Index: -8.2200
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: -0.6046
    Cell Significance Index: -6.0500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6139
    Cell Significance Index: -13.0300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6527
    Cell Significance Index: -20.9100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7404
    Cell Significance Index: -24.2400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.7849
    Cell Significance Index: -6.0500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.8016
    Cell Significance Index: -15.8500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.8211
    Cell Significance Index: -12.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8412
    Cell Significance Index: -26.7900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.8937
    Cell Significance Index: -8.2300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.9148
    Cell Significance Index: -59.0200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.9314
    Cell Significance Index: -48.9000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.9678
    Cell Significance Index: -20.9100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.9684
    Cell Significance Index: -18.9000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.9924
    Cell Significance Index: -10.6400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.9960
    Cell Significance Index: -12.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PKP4 is a member of the plakophilin family, which is characterized by its ability to bind to other proteins and contribute to the formation of cell-cell adhesion complexes. The gene's expression is widespread, with significant levels detected in epithelial tissues, including the skin, lung, and eye. PKP4's structure consists of three Ig-like domains and a cytoplasmic tail, which mediates interactions with other proteins and the cytoskeleton. The gene's expression is tightly regulated, with studies suggesting that PKP4 is involved in the regulation of cell proliferation, differentiation, and survival. **Pathways and Functions** PKP4's involvement in cell-cell adhesion is mediated through its interactions with other proteins, including cadherins and catenins. The gene's expression is regulated by various signaling pathways, including the Rho GTPase cycle, which is involved in the regulation of cell adhesion and cytoskeletal organization. PKP4's role in maintaining tissue integrity is critical, as disruptions in cell-cell junctions can lead to tissue damage and disease. The gene's involvement in signaling pathways, including the regulation of cytokinesis and gtpase activity, highlights its importance in cellular processes beyond cell adhesion. PKP4's functions can be summarized as follows: 1. Cell-cell adhesion: PKP4 contributes to the formation and maintenance of desmosomes, which are crucial for maintaining tissue integrity. 2. Signaling: PKP4 is involved in the regulation of signaling pathways, including the Rho GTPase cycle, which is critical for maintaining tissue homeostasis. 3. Cytoskeletal organization: PKP4's interactions with the cytoskeleton are essential for maintaining cell shape and preventing cell migration. 4. Cell proliferation and differentiation: PKP4's expression is regulated by various signaling pathways, which are critical for maintaining tissue homeostasis. **Clinical Significance** Disruptions in PKP4 expression have been implicated in various diseases, including: 1. Epidermolysis bullosa simplex (EBS): A genetic disorder characterized by skin blistering and fragility, which is caused by mutations in the PKP4 gene. 2. Epidermolysis bullosa junctional (EBJ): A genetic disorder characterized by skin blistering and fragility, which is caused by mutations in the PKP4 gene. 3. Keratinization disorders: PKP4's involvement in the formation of the cornified envelope highlights its importance in maintaining skin integrity. 4. Cancer: PKP4's role in maintaining tissue integrity and preventing cell migration makes it a potential target for cancer therapy. In conclusion, PKP4 is a critical gene involved in the formation and maintenance of cell-cell adhesion complexes, particularly in epithelial tissues. Its involvement in signaling pathways, cytoskeletal organization, and cellular processes highlights its importance in maintaining tissue homeostasis. Disruptions in PKP4 expression have been implicated in various diseases, highlighting the need for further research into the gene's role in human health and disease.

Genular Protein ID: 697327569

Symbol: PKP4_HUMAN

Name: Plakophilin-4

UniProtKB Accession Codes:

Q99569 Q86W91

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 23 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 5 RefSeq 5 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8937994

Title: Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: evidence for a subfamily of closely related proteins.

PubMed ID: 8937994

DOI: 10.1242/jcs.109.11.2767

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17115030

Title: The armadillo protein p0071 regulates Rho signalling during cytokinesis.

PubMed ID: 17115030

DOI: 10.1038/ncb1504

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19706687

Title: PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

PubMed ID: 19706687

DOI: 10.1242/jcs.046854

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25009281

Title: DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.

PubMed ID: 25009281

DOI: 10.1091/mbc.e13-08-0492

PubMed ID: 29034528

Title: Patients with a new variant of endemic pemphigus foliaceus have autoantibodies against arrector pili muscle, colocalizing with MYZAP, p0071, desmoplakins 1 and 2 and ARVCF.

PubMed ID: 29034528

DOI: 10.1111/ced.13214

PubMed ID: 30479852

Title: Subclinical oral involvement in patients with endemic pemphigus foliaceus.

PubMed ID: 30479852

DOI: 10.5826/dpc.0804a02

Sequence Information:

  • Length: 1192
  • Mass: 131868
  • Checksum: 48EA1579E323E019
  • Sequence:
    • MPAPEQASLV EEGQPQTRQE AASTGPGMEP ETTATTILAS VKEQELQFQR LTRELEVERQ 
IVASQLERCR LGAESPSIAS TSSTEKSFPW RSTDVPNTGV SKPRVSDAVQ PNNYLIRTEP 
EQGTLYSPEQ TSLHESEGSL GNSRSSTQMN SYSDSGYQEA GSFHNSQNVS KADNRQQHSF 
IGSTNNHVVR NSRAEGQTLV QPSVANRAMR RVSSVPSRAQ SPSYVISTGV SPSRGSLRTS 
LGSGFGSPSV TDPRPLNPSA YSSTTLPAAR AASPYSQRPA SPTAIRRIGS VTSRQTSNPN 
GPTPQYQTTA RVGSPLTLTD AQTRVASPSQ GQVGSSSPKR SGMTAVPQHL GPSLQRTVHD 
MEQFGQQQYD IYERMVPPRP DSLTGLRSSY ASQHSQLGQD LRSAVSPDLH ITPIYEGRTY 
YSPVYRSPNH GTVELQGSQT ALYRTGSVGI GNLQRTSSQR STLTYQRNNY ALNTTATYAE 
PYRPIQYRVQ ECNYNRLQHA VPADDGTTRS PSIDSIQKDP REFAWRDPEL PEVIHMLQHQ 
FPSVQANAAA YLQHLCFGDN KVKMEVCRLG GIKHLVDLLD HRVLEVQKNA CGALRNLVFG 
KSTDENKIAM KNVGGIPALL RLLRKSIDAE VRELVTGVLW NLSSCDAVKM TIIRDALSTL 
TNTVIVPHSG WNNSSFDDDH KIKFQTSLVL RNTTGCLRNL SSAGEEARKQ MRSCEGLVDS 
LLYVIHTCVN TSDYDSKTVE NCVCTLRNLS YRLELEVPQA RLLGLNELDD LLGKESPSKD 
SEPSCWGKKK KKKKRTPQED QWDGVGPIPG LSKSPKGVEM LWHPSVVKPY LTLLAESSNP 
ATLEGSAGSL QNLSAGNWKF AAYIRAAVRK EKGLPILVEL LRMDNDRVVS SVATALRNMA 
LDVRNKELIG KYAMRDLVNR LPGGNGPSVL SDETMAAICC ALHEVTSKNM ENAKALADSG 
GIEKLVNITK GRGDRSSLKV VKAAAQVLNT LWQYRDLRSI YKKDGWNQNH FITPVSTLER 
DRFKSHPSLS TTNQQMSPII QSVGSTSSSP ALLGIRDPRS EYDRTQPPMQ YYNSQGDATH 
KGLYPGSSKP SPIYISSYSS PAREQNRRLQ HQQLYYSQDD SNRKNFDAYR LYLQSPHSYE 
DPYFDDRVHF PASTDYSTQY GLKSTTNYVD FYSTKRPSYR AEQYPGSPDS WV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.