Details for: ITGA8
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 45.6915
Cell Significance Index: -18.5600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 41.6841
Cell Significance Index: -19.6800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 19.4764
Cell Significance Index: -18.6000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.5241
Cell Significance Index: -12.0900 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 4.4692
Cell Significance Index: 27.6500 - Cell Name: glomerular capillary endothelial cell (CL1001005)
Fold Change: 2.7502
Cell Significance Index: 10.2500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.6268
Cell Significance Index: 176.6300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.4558
Cell Significance Index: 70.0800 - Cell Name: myometrial cell (CL0002366)
Fold Change: 2.3105
Cell Significance Index: 26.6100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.1063
Cell Significance Index: 956.0000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.0898
Cell Significance Index: 44.6700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.7990
Cell Significance Index: 57.6200 - Cell Name: endocardial cell (CL0002350)
Fold Change: 1.6649
Cell Significance Index: 9.8300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.6299
Cell Significance Index: 56.6400 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.2177
Cell Significance Index: 9.3400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.7459
Cell Significance Index: 16.1600 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.6973
Cell Significance Index: 16.8900 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.5687
Cell Significance Index: 5.8900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.3882
Cell Significance Index: 5.5600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.3789
Cell Significance Index: 7.9300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3733
Cell Significance Index: 16.9200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3396
Cell Significance Index: 55.2400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3156
Cell Significance Index: 19.4000 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.2833
Cell Significance Index: 2.3800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1970
Cell Significance Index: 25.2500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1954
Cell Significance Index: 37.2000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1756
Cell Significance Index: 121.4800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1733
Cell Significance Index: 62.1500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.1599
Cell Significance Index: 2.3000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1224
Cell Significance Index: 7.3500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0813
Cell Significance Index: 16.3000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0466
Cell Significance Index: 0.7800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0263
Cell Significance Index: 16.7200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0025
Cell Significance Index: -4.7600 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.0097
Cell Significance Index: -0.1500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0117
Cell Significance Index: -21.5300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0143
Cell Significance Index: -22.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0166
Cell Significance Index: -22.6300 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0184
Cell Significance Index: -0.2500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0237
Cell Significance Index: -17.5200 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0237
Cell Significance Index: -0.5900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0284
Cell Significance Index: -20.8300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0292
Cell Significance Index: -22.1200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0360
Cell Significance Index: -20.3100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0382
Cell Significance Index: -20.8600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0454
Cell Significance Index: -8.1800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0516
Cell Significance Index: -14.8500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0611
Cell Significance Index: -12.1200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0676
Cell Significance Index: -1.4400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0677
Cell Significance Index: -6.7000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0742
Cell Significance Index: -1.7800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0780
Cell Significance Index: -8.1200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.0811
Cell Significance Index: -8.8300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0870
Cell Significance Index: -11.9500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0930
Cell Significance Index: -19.5900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0948
Cell Significance Index: -16.1800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0994
Cell Significance Index: -14.4500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1066
Cell Significance Index: -3.0700 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1096
Cell Significance Index: -2.2000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1102
Cell Significance Index: -2.7500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1323
Cell Significance Index: -16.2700 - Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
Fold Change: -0.1430
Cell Significance Index: -1.4500 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.1435
Cell Significance Index: -1.2200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1531
Cell Significance Index: -10.5900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1625
Cell Significance Index: -20.9900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1648
Cell Significance Index: -18.8800 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.1682
Cell Significance Index: -1.6000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1754
Cell Significance Index: -20.4400 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.1789
Cell Significance Index: -2.3200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1938
Cell Significance Index: -4.0200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2019
Cell Significance Index: -20.6200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2048
Cell Significance Index: -3.5100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2177
Cell Significance Index: -3.2800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2228
Cell Significance Index: -17.1000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2600
Cell Significance Index: -13.5500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2624
Cell Significance Index: -20.7800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2826
Cell Significance Index: -21.0600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2838
Cell Significance Index: -9.2900 - Cell Name: sebaceous gland cell (CL2000021)
Fold Change: -0.3014
Cell Significance Index: -0.3900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3038
Cell Significance Index: -19.6000 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.3215
Cell Significance Index: -13.9800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3381
Cell Significance Index: -18.9700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3397
Cell Significance Index: -7.3400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3435
Cell Significance Index: -21.6500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3438
Cell Significance Index: -10.9500 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3546
Cell Significance Index: -7.4000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3617
Cell Significance Index: -10.6600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3685
Cell Significance Index: -12.9100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3696
Cell Significance Index: -10.3300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3794
Cell Significance Index: -19.9200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4043
Cell Significance Index: -21.0000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4128
Cell Significance Index: -10.6100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4169
Cell Significance Index: -19.6000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4228
Cell Significance Index: -18.7000 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.4555
Cell Significance Index: -8.8900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.4778
Cell Significance Index: -22.2800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.4865
Cell Significance Index: -6.2300 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.4867
Cell Significance Index: -7.2800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.4984
Cell Significance Index: -12.1600 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.5064
Cell Significance Index: -3.1700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2760106823
Symbol: ITA8_HUMAN
Name: Integrin alpha-8
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 7768999
Title: Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells.
PubMed ID: 7768999
PubMed ID: 10504498
Title: Alpha8 integrin in glomerular mesangial cells and in experimental glomerulonephritis.
PubMed ID: 10504498
PubMed ID: 12415008
Title: Integrin alpha8beta1 mediates adhesion to LAP-TGFbeta1.
PubMed ID: 12415008
DOI: 10.1242/jcs.00145
PubMed ID: 15721307
Title: Integrin alpha8beta1-fibronectin interactions promote cell survival via PI3 kinase pathway.
PubMed ID: 15721307
PubMed ID: 24439109
Title: Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans.
PubMed ID: 24439109
PubMed ID: 15579315
Title: Genomic organization and sequence variation of the human integrin subunit alpha8 gene (ITGA8).
PubMed ID: 15579315
Sequence Information:
- Length: 1063
- Mass: 117474
- Checksum: 8F9614BDBB897D77
- Sequence:
MSPGASRGPR GSQAPLIAPL CCAAAALGML LWSPACQAFN LDVEKLTVYS GPKGSYFGYA VDFHIPDART ASVLVGAPKA NTSQPDIVEG GAVYYCPWPA EGSAQCRQIP FDTTNNRKIR VNGTKEPIEF KSNQWFGATV KAHKGKVVAC APLYHWRTLK PTPEKDPVGT CYVAIQNFSA YAEFSPCRNS NADPEGQGYC QAGFSLDFYK NGDLIVGGPG SFYWQGQVIT ASVADIIANY SFKDILRKLA GEKQTEVAPA SYDDSYLGYS VAAGEFTGDS QQELVAGIPR GAQNFGYVSI INSTDMTFIQ NFTGEQMASY FGYTVVVSDV NSDGLDDVLV GAPLFMEREF ESNPREVGQI YLYLQVSSLL FRDPQILTGT ETFGRFGSAM AHLGDLNQDG YNDIAIGVPF AGKDQRGKVL IYNGNKDGLN TKPSQVLQGV WASHAVPSGF GFTLRGDSDI DKNDYPDLIV GAFGTGKVAV YRARPVVTVD AQLLLHPMII NLENKTCQVP DSMTSAACFS LRVCASVTGQ SIANTIVLMA EVQLDSLKQK GAIKRTLFLD NHQAHRVFPL VIKRQKSHQC QDFIVYLRDE TEFRDKLSPI NISLNYSLDE STFKEGLEVK PILNYYRENI VSEQAHILVD CGEDNLCVPD LKLSARPDKH QVIIGDENHL MLIINARNEG EGAYEAELFV MIPEEADYVG IERNNKGFRP LSCEYKMENV TRMVVCDLGN PMVSGTNYSL GLRFAVPRLE KTNMSINFDL QIRSSNKDNP DSNFVSLQIN ITAVAQVEIR GVSHPPQIVL PIHNWEPEEE PHKEEEVGPL VEHIYELHNI GPSTISDTIL EVGWPFSARD EFLLYIFHIQ TLGPLQCQPN PNINPQDIKP AASPEDTPEL SAFLRNSTIP HLVRKRDVHV VEFHRQSPAK ILNCTNIECL QISCAVGRLE GGESAVLKVR SRLWAHTFLQ RKNDPYALAS LVSFEVKKMP YTDQPAKLPE GSIVIKTSVI WATPNVSFSI PLWVIILAIL LGLLVLAILT LALWKCGFFD RARPPQEDMT DREQLTNDKT PEA
Genular Protein ID: 101657975
Symbol: B4DN28_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1048
- Mass: 115947
- Checksum: 87548202C198F133
- Sequence:
MSPGASRGPR GSQAPLIAPL CCAAAALGML LWSPACQAFN LDVEKLTVYS GPKGSYFGYA VDFHIPDART ASVLVGAPKA NTSQPDIVEG GAVYYCPWPA EGSAQCRQIP FDTTNNRKIR VNGTKEPIEF KSNQWFGATV KAHKGKVVAC APLYHWRTLK PTPEKDPVGT CYVAIQNFSA YAEFSPCRNS NADPEGQGYC QAGFSLDFYK NGDLIVGGPG SFYWQGQVIT ASVADIIANY SFKDILRKLA GEKQTEVAPA SYDDSYLELV AGIPRGAQNF GYVSIINSTD MTFIQNFTGE QMASYFGYTV VVSDVNSDGL DDVLVGAPLF MEREFESNPR EVGQIYLYLQ VSSLLFRDPQ ILTGTETFGR FGSAMAHLGD LNQDGYNDIA IGVPFAGKDQ RGKVLIYNGN KDGLNTKPSQ VLQGVWASHA VPSGFGFTLR GDSDIDKNDY PDLIVGAFGT GKVAVYRARP VVTVDAQLLL HPMIINLENK TCQVPDSMTS AACFSLRVCA SVTGQSIANT IVLMAEVQLD SLKQKGAIKR TLFLDNHQAH RVFPLVIKRQ KSHQCQDFIV YLRDETEFRD KLSPINISLN YSLDESTFKE GLEVKPILNY YRENIVSEQA HILVDCGEDN LCVPDLKLSA RPDKHQVIIG DENHLMLIIN ARNEGEGAYE AELFVMIPEE ADYVGIERNN KGFRPLSCEY KMENVTRMVV CDLGNPMVSG TNYSLGLRFA VPRLEKTNMS INFDLQIRSS NKDNPDSNFV SLQINITAVA QVEIRGVSHP PQIVLPIHNW EPEEEPHKEE EVGPLVEHIY ELHNIGPSTI SDTILEVGWP FSARDEFLLY IFHIQTLGPL QCQPNPNINP QDIKPAASPE DTPELSAFLR NSTIPHLVRK RDVHVVEFHR QSPAKILNCT NIECLQISCA VGRLEGGESA VLKVRSRLWA HTFLQRKNDP YALASLVSFE VKKMPYTDQP AKLPEGSIAI KTSVIWATPN VSFSIPLWVI ILAILLGLLV LAILTLALWK CGFFDRARPP QEDMTDREQL TNDKTPEA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.