Details for: DCHS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 47.3894
Cell Significance Index: -12.0200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 26.5103
Cell Significance Index: -10.7700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 25.8196
Cell Significance Index: -12.1900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 11.2910
Cell Significance Index: -10.7800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.0714
Cell Significance Index: -12.1200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.1566
Cell Significance Index: -4.7200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.6054
Cell Significance Index: 20.5600 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.5349
Cell Significance Index: 24.6300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.1342
Cell Significance Index: 59.0800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.0243
Cell Significance Index: 21.4400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.7349
Cell Significance Index: 139.8600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6845
Cell Significance Index: 67.7200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.5919
Cell Significance Index: 12.9600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.5844
Cell Significance Index: 9.7800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5609
Cell Significance Index: 11.9500 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.4564
Cell Significance Index: 7.2400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.4243
Cell Significance Index: 4.8200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.4225
Cell Significance Index: 12.1100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3697
Cell Significance Index: 333.8000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3266
Cell Significance Index: 44.8500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3241
Cell Significance Index: 52.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2848
Cell Significance Index: 36.5100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2775
Cell Significance Index: 30.1800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2286
Cell Significance Index: 14.0500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1921
Cell Significance Index: 11.5300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1558
Cell Significance Index: 8.7400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1498
Cell Significance Index: 53.7300 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.1463
Cell Significance Index: 1.5900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1329
Cell Significance Index: 3.5000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1142
Cell Significance Index: 0.6900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1031
Cell Significance Index: 71.3300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0901
Cell Significance Index: 6.2300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0592
Cell Significance Index: 11.8700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0475
Cell Significance Index: 1.1400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0375
Cell Significance Index: 1.0800 - Cell Name: endocardial cell (CL0002350)
Fold Change: 0.0339
Cell Significance Index: 0.2000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0077
Cell Significance Index: 1.5200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0042
Cell Significance Index: 0.0900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0025
Cell Significance Index: 1.1000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0008
Cell Significance Index: 0.0200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0011
Cell Significance Index: -2.0100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0068
Cell Significance Index: -0.2400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0087
Cell Significance Index: -16.0900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0087
Cell Significance Index: -13.3600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0115
Cell Significance Index: -15.6600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0155
Cell Significance Index: -9.8400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0155
Cell Significance Index: -11.3700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0159
Cell Significance Index: -12.0000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0176
Cell Significance Index: -13.0300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0186
Cell Significance Index: -8.4400 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0201
Cell Significance Index: -10.9800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0228
Cell Significance Index: -12.8800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0229
Cell Significance Index: -14.2700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0238
Cell Significance Index: -1.0800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0266
Cell Significance Index: -1.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0362
Cell Significance Index: -10.4300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0369
Cell Significance Index: -6.6600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0570
Cell Significance Index: -6.6400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0619
Cell Significance Index: -7.0900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0657
Cell Significance Index: -0.9900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0657
Cell Significance Index: -11.2200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0683
Cell Significance Index: -14.3800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0694
Cell Significance Index: -10.0900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0752
Cell Significance Index: -9.2500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0783
Cell Significance Index: -5.0500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0822
Cell Significance Index: -5.8100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0881
Cell Significance Index: -11.3800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0973
Cell Significance Index: -9.9400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0999
Cell Significance Index: -1.4300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1104
Cell Significance Index: -13.0200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1141
Cell Significance Index: -11.8800 - Cell Name: chondroblast (CL0000058)
Fold Change: -0.1141
Cell Significance Index: -0.6700 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: -0.1294
Cell Significance Index: -1.2300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1419
Cell Significance Index: -6.6200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1429
Cell Significance Index: -5.4100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1447
Cell Significance Index: -11.1100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1460
Cell Significance Index: -6.4600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1511
Cell Significance Index: -2.9500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1520
Cell Significance Index: -12.0400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1563
Cell Significance Index: -10.5100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1592
Cell Significance Index: -5.1000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1668
Cell Significance Index: -12.4300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1733
Cell Significance Index: -9.1000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1737
Cell Significance Index: -10.9500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1775
Cell Significance Index: -8.3400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1777
Cell Significance Index: -4.9700 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.1805
Cell Significance Index: -1.1300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1809
Cell Significance Index: -3.8400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2164
Cell Significance Index: -7.5200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2210
Cell Significance Index: -5.6800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2376
Cell Significance Index: -7.7800 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2454
Cell Significance Index: -3.5300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2466
Cell Significance Index: -12.8100 - Cell Name: myometrial cell (CL0002366)
Fold Change: -0.2483
Cell Significance Index: -2.8600 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: -0.2530
Cell Significance Index: -1.5700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2538
Cell Significance Index: -8.8900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2590
Cell Significance Index: -8.2500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2695
Cell Significance Index: -7.6900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2864
Cell Significance Index: -5.7500 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: -0.2913
Cell Significance Index: -2.1400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 14338809
Symbol: PCD16_HUMAN
Name: Protocadherin-16
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11597768
Title: Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.
PubMed ID: 11597768
PubMed ID: 9199196
Title: Multiple cadherins are expressed in human fibroblasts.
PubMed ID: 9199196
PubMed ID: 26258302
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 24056717
Title: Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.
PubMed ID: 24056717
DOI: 10.1038/ng.2765
Sequence Information:
- Length: 3298
- Mass: 346181
- Checksum: 6EE8D28BEF0795DB
- Sequence:
MQKELGIVPS CPGMKSPRPH LLLPLLLLLL LLLGAGVPGA WGQAGSLDLQ IDEEQPAGTL IGDISAGLPA GTAAPLMYFI SAQEGSGVGT DLAIDEHSGV VRTARVLDRE QRDRYRFTAV TPDGATVEVT VRVADINDHA PAFPQARAAL QVPEHTAFGT RYPLEPARDA DAGRLGTQGY ALSGDGAGET FRLETRPGPD GTPVPELVVT GELDRENRSH YMLQLEAYDG GSPPRRAQAL LDVTLLDIND HAPAFNQSRY HAVVSESLAP GSPVLQVFAS DADAGVNGAV TYEINRRQSE GDGPFSIDAH TGLLQLERPL DFEQRRVHEL VVQARDGGAH PELGSAFVTV HVRDANDNQP SMTVIFLSAD GSPQVSEAAP PGQLVARISV SDPDDGDFAH VNVSLEGGEG HFALSTQDSV IYLVCVARRL DREERDAYNL RVTATDSGSP PLRAEAAFVL HVTDVNDNAP AFDRQLYRPE PLPEVALPGS FVVRVTARDP DQGTNGQVTY SLAPGAHTHW FSIDPTSGII TTAASLDYEL EPQPQLIVVA TDGGLPPLAS SATVSVALQD VNDNEPQFQR TFYNASLPEG TQPGTCFLQV TATDADSGPF GLLSYSLGAG LGSSGSPPFR IDAHSGDVCT TRTLDRDQGP SSFDFTVTAV DGGGLKSMVY VKVFLSDEND NPPQFYPREY AASISAQSPP GTAVLRLRAH DPDQGSHGRL SYHILAGNSP PLFTLDEQSG LLTVAWPLAR RANSVVQLEI GAEDGGGLQA EPSARVDISI VPGTPTPPIF EQLQYVFSVP EDVAPGTSVG IVQAHNPPGR LAPVTLSLSG GDPRGLFSLD AVSGLLQTLR PLDRELLGPV LELEVRAGSG VPPAFAVARV RVLLDDVNDN SPAFPAPEDT VLLPPNTAPG TPIYTLRALD PDSGVNSRVT FTLLAGGGGA FTVDPTTGHV RLMRPLGPSG GPAHELELEA RDGGSPPRTS HFRLRVVVQD VGTRGLAPRF NSPTYRVDLP SGTTAGTQVL QVQAQAPDGG PITYHLAAEG ASSPFGLEPQ SGWLWVRAAL DREAQELYIL KVMAVSGSKA ELGQQTGTAT VRVSILNQNE HSPRLSEDPT FLAVAENQPP GTSVGRVFAT DRDSGPNGRL TYSLQQLSED SKAFRIHPQT GEVTTLQTLD REQQSSYQLL VQVQDGGSPP RSTTGTVHVA VLDLNDNSPT FLQASGAAGG GLPIQVPDRV PPGTLVTTLQ AKDPDEGENG TILYTLTGPG SELFSLHPHS GELLTAAPLI RAERPHYVLT LSAHDQGSPP RSASLQLLVQ VLPSARLAEP PPDLAERDPA APVPVVLTVT AAEGLRPGSL LGSVAAPEPA GVGALTYTLV GGADPEGTFA LDAASGRLYL ARPLDFEAGP PWRALTVRAE GPGGAGARLL RVQVQVQDEN EHAPAFARDP LALALPENPE PGAALYTFRA SDADGPGPNS DVRYRLLRQE PPVPALRLDA RTGALSAPRG LDRETTPALL LLVEATDRPA NASRRRAARV SARVFVTDEN DNAPVFASPS RVRLPEDQPP GPAALHVVAR DPDLGEAARV SYRLASGGDG HFRLHSSTGA LSVVRPLDRE QRAEHVLTVV ASDHGSPPRS ATQVLTVSVA DVNDEAPTFQ QQEYSVLLRE NNPPGTSLLT LRATDPDVGA NGQVTYGGVS SESFSLDPDT GVLTTLRALD REEQEEINLT VYAQDRGSPP QLTHVTVRVA VEDENDHAPT FGSAHLSLEV PEGQDPQTLT MLRASDPDVG ANGQLQYRIL DGDPSGAFVL DLASGEFGTM RPLDREVEPA FQLRIEARDG GQPALSATLL LTVTVLDAND HAPAFPVPAY SVEVPEDVPA GTLLLQLQAH DPDAGANGHV TYYLGAGTAG AFLLEPSSGE LRTAAALDRE QCPSYTFSVS AVDGAAAGPL STTVSVTITV RDVNDHAPTF PTSPLRLRLP RPGPSFSTPT LALATLRAED RDAGANASIL YRLAGTPPPG TTVDSYTGEI RVARSPVALG PRDRVLFIVA TDLGRPARSA TGVIIVGLQG EAERGPRFPR ASSEATIREN APPGTPIVSP RAVHAGGTNG PITYSILSGN EKGTFSIQPS TGAITVRSAE GLDFEVSPRL RLVLQAESGG AFAFTVLTLT LQDANDNAPR FLRPHYVAFL PESRPLEGPL LQVEADDLDQ GSGGQISYSL AASQPARGLF HVDPTTGTIT TTAILDREIW AETRLVLMAT DRGSPALVGS ATLTVMVIDT NDNRPTIPQP WELRVSEDAL LGSEIAQVTG NDVDSGPVLW YVLSPSGPQD PFSVGRYGGR VSLTGPLDFE QCDRYQLQLL AHDGPHEGRA NLTVLVEDVN DNAPAFSQSL YQVMLLEHTP PGSAILSVSA TDRDSGANGH ISYHLASPAD GFSVDPNNGT LFTIVGTVAL GHDGSGAVDV VLEARDHGAP GRAARATVHV QLQDQNDHAP SFTLSHYRVA VTEDLPPGST LLTLEATDAD GSRSHAAVDY SIISGNWGRV FQLEPRLAEA GESAGPGPRA LGCLVLLEPL DFESLTQYNL TVAAADRGQP PQSSVVPVTV TVLDVNDNPP VFTRASYRVT VPEDTPVGAE LLHVEASDAD PGPHGLVRFT VSSGDPSGLF ELDESSGTLR LAHALDCETQ ARHQLVVQAA DPAGAHFALA PVTIEVQDVN DHGPAFPLNL LSTSVAENQP PGTLVTTLHA IDGDAGAFGR LRYSLLEAGP GPEGREAFAL NSSTGELRAR VPFDYEHTES FRLLVGAADA GNLSASVTVS VLVTGEDEYD PVFLAPAFHF QVPEGARRGH SLGHVQATDE DGGADGLVLY SLATSSPYFG INQTTGALYL RVDSRAPGSG TATSGGGGRT RREAPRELRL EVIARGPLPG SRSATVPVTV DITHTALGLA PDLNLLLVGA VAASLGVVVV LALAALVLGL VRARSRKAEA APGPMSQAAP LASDSLQKLG REPPSPPPSE HLYHQTLPSY GGPGAGGPYP RGGSLDPSHS SGRGSAEAAE DDEIRMINEF PRVASVASSL AARGPDSGIQ QDADGLSDTS CEPPAPDTWY KGRKAGLLLP GAGATLYREE GPPATATAFL GGCGLSPAPT GDYGFPADGK PCVAGALTAI VAGEEELRGS YNWDYLLSWC PQFQPLASVF TEIARLKDEA RPCPPAPRID PPPLITAVAH PGAKSVPPKP ANTAAARAIF PPASHRSPIS HEGSLSSAAM SPSFSPSLSP LAARSPVVSP FGVAQGPSAS ALSAESGLEP PDDTELHI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.