Details for: EIF3H

Gene ID: 8667

Symbol: EIF3H

Ensembl ID: ENSG00000147677

Description: eukaryotic translation initiation factor 3 subunit H

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-HSA-72662)
  • Cap-dependent translation initiation
    (R-HSA-72737)
  • Eukaryotic translation initiation
    (R-HSA-72613)
  • Formation of a pool of free 40s subunits
    (R-HSA-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-HSA-72695)
  • Gtp hydrolysis and joining of the 60s ribosomal subunit
    (R-HSA-72706)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-HSA-156827)
  • Metabolism of proteins
    (R-HSA-392499)
  • Ribosomal scanning and start codon recognition
    (R-HSA-72702)
  • Translation
    (R-HSA-72766)
  • Translation initiation complex formation
    (R-HSA-72649)
  • Cytosol
    (GO:0005829)
  • Eukaryotic 43s preinitiation complex
    (GO:0016282)
  • Eukaryotic 48s preinitiation complex
    (GO:0033290)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Eukaryotic translation initiation factor 3 complex, eif3m
    (GO:0071541)
  • Extracellular exosome
    (GO:0070062)
  • Formation of cytoplasmic translation initiation complex
    (GO:0001732)
  • Membrane
    (GO:0016020)
  • Metal-dependent deubiquitinase activity
    (GO:0140492)
  • Metallopeptidase activity
    (GO:0008237)
  • Negative regulation of proteasomal ubiquitin-dependent protein catabolic process
    (GO:0032435)
  • Protein binding
    (GO:0005515)
  • Regulation of translational initiation
    (GO:0006446)
  • Rna binding
    (GO:0003723)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 560.9944
    Cell Significance Index: -87.2600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 276.5886
    Cell Significance Index: -113.9400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 266.2399
    Cell Significance Index: -67.5300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 249.4479
    Cell Significance Index: -101.3400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 236.0509
    Cell Significance Index: -111.4500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 220.1657
    Cell Significance Index: -113.2500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 166.5072
    Cell Significance Index: -111.7300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 107.7987
    Cell Significance Index: -102.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 84.2042
    Cell Significance Index: -103.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 28.3068
    Cell Significance Index: -111.7000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 25.6068
    Cell Significance Index: -78.6500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 23.8012
    Cell Significance Index: -63.7600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.7270
    Cell Significance Index: -34.4200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 4.5295
    Cell Significance Index: 94.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.2592
    Cell Significance Index: 294.5500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 3.9719
    Cell Significance Index: 43.1800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.7013
    Cell Significance Index: 508.2900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.4950
    Cell Significance Index: 164.2600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 3.4673
    Cell Significance Index: 447.9500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.4522
    Cell Significance Index: 92.1800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 3.3509
    Cell Significance Index: 216.1800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.3213
    Cell Significance Index: 42.5400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.3060
    Cell Significance Index: 246.3900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.0595
    Cell Significance Index: 360.8100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 3.0571
    Cell Significance Index: 216.2100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.8980
    Cell Significance Index: 85.1100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.8099
    Cell Significance Index: 131.0100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.8019
    Cell Significance Index: 344.5200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.7563
    Cell Significance Index: 496.8800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.7180
    Cell Significance Index: 94.4500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 2.6909
    Cell Significance Index: 1189.7000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.3822
    Cell Significance Index: 62.6400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.2071
    Cell Significance Index: 1205.3700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.1481
    Cell Significance Index: 37.9600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.0772
    Cell Significance Index: 56.5400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.8887
    Cell Significance Index: 15.0800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7151
    Cell Significance Index: 340.3700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.6790
    Cell Significance Index: 38.7900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.5462
    Cell Significance Index: 198.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4654
    Cell Significance Index: 293.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.3850
    Cell Significance Index: 236.4900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.3138
    Cell Significance Index: 37.6600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1563
    Cell Significance Index: 60.0700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7686
    Cell Significance Index: 693.9700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7672
    Cell Significance Index: 14.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7336
    Cell Significance Index: 139.6000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7221
    Cell Significance Index: 6.6500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5677
    Cell Significance Index: 203.6300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5482
    Cell Significance Index: 30.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4583
    Cell Significance Index: 24.0600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3999
    Cell Significance Index: 24.0100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.3627
    Cell Significance Index: 4.1200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2384
    Cell Significance Index: 12.4200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1947
    Cell Significance Index: 5.4400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1014
    Cell Significance Index: 76.7300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0986
    Cell Significance Index: 1.6500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0249
    Cell Significance Index: 18.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0005
    Cell Significance Index: 0.9400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0181
    Cell Significance Index: -13.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0226
    Cell Significance Index: -41.7100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0348
    Cell Significance Index: -2.6700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0352
    Cell Significance Index: -54.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0467
    Cell Significance Index: -4.7700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0472
    Cell Significance Index: -29.9600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0554
    Cell Significance Index: -75.3800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0692
    Cell Significance Index: -43.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0728
    Cell Significance Index: -33.0500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1287
    Cell Significance Index: -72.5800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1466
    Cell Significance Index: -9.0100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1688
    Cell Significance Index: -5.9300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1917
    Cell Significance Index: -12.0800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.2190
    Cell Significance Index: -21.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2463
    Cell Significance Index: -51.8800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3363
    Cell Significance Index: -96.7500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4291
    Cell Significance Index: -62.3700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4870
    Cell Significance Index: -5.8100
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.5297
    Cell Significance Index: -3.2600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5402
    Cell Significance Index: -13.8000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5976
    Cell Significance Index: -19.1400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6126
    Cell Significance Index: -71.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6161
    Cell Significance Index: -70.5900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7759
    Cell Significance Index: -52.1800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.8502
    Cell Significance Index: -11.6000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.8531
    Cell Significance Index: -22.8200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.8595
    Cell Significance Index: -98.1100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8979
    Cell Significance Index: -71.1100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.0164
    Cell Significance Index: -105.8300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.2325
    Cell Significance Index: -31.6800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.2494
    Cell Significance Index: -55.2700
  • Cell Name: theca cell (CL0000503)
    Fold Change: -1.2749
    Cell Significance Index: -7.4900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.3667
    Cell Significance Index: -29.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.4362
    Cell Significance Index: -65.1000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.5068
    Cell Significance Index: -92.3800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.5099
    Cell Significance Index: -25.8800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.5142
    Cell Significance Index: -57.3400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.6126
    Cell Significance Index: -27.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.6226
    Cell Significance Index: -40.5600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.8122
    Cell Significance Index: -18.7600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -2.0176
    Cell Significance Index: -12.1900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -2.0627
    Cell Significance Index: -55.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EIF3H is a conserved subunit of the eukaryotic translation initiation complex, which is composed of multiple subunits. The protein is highly expressed in various cell types, including mesodermal cells, mature alpha-beta T cells, blood cells, and basal cells of prostate epithelium. EIF3H exhibits metal-dependent deubiquitinase activity and metallopeptidase activity, suggesting its role in regulating protein degradation and translation. Additionally, EIF3H is involved in the regulation of translational initiation, ribosomal scanning, and start codon recognition. **Pathways and Functions:** EIF3H is integral to several key pathways, including: 1. **Activation of mRNA upon binding of the cap-binding complex and eIFs**: EIF3H facilitates the interaction between the cap-binding complex and eIFs, leading to the activation of mRNA translation. 2. **Binding to 40S ribosomal subunit**: EIF3H binds to the 40S ribosomal subunit, forming the eIF3 complex, which is essential for the initiation of translation. 3. **Regulation of translational initiation**: EIF3H regulates the recruitment of ribosomal subunits to the mRNA and the initiation of translation. 4. **Regulation of proteasomal ubiquitin-dependent protein catabolism**: EIF3H is involved in the regulation of protein degradation through the ubiquitin-proteasome pathway. 5. **Metal-dependent deubiquitinase activity**: EIF3H exhibits metal-dependent deubiquitinase activity, which is essential for the regulation of protein degradation and translation. **Clinical Significance:** EIF3H's dysregulation has been implicated in various diseases, including: 1. **Ceruloplasmin expression regulation**: EIF3H is involved in the translational silencing of ceruloplasmin expression, which is a hallmark of Wilson's disease. 2. **Prostate cancer**: EIF3H is overexpressed in prostate cancer cells, suggesting its potential role in the development and progression of prostate cancer. 3. **Immune system disorders**: EIF3H is expressed in various immune cells, including T cells and B cells, and its dysregulation may contribute to immune system disorders, such as autoimmune diseases. In conclusion, EIF3H is a crucial component of the eukaryotic translation initiation complex, and its dysregulation has significant implications for various diseases. Further research is needed to fully understand the mechanisms underlying EIF3H's functions and to explore its potential as a therapeutic target for diseases associated with its dysregulation.

Genular Protein ID: 334043153

Symbol: EIF3H_HUMAN

Name: eIF-3-gamma

UniProtKB Accession Codes:

O15372

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 11 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9341143

Title: Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.

PubMed ID: 9341143

DOI: 10.1074/jbc.272.43.27042

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16286006

Title: mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

PubMed ID: 16286006

DOI: 10.1016/j.cell.2005.10.024

PubMed ID: 15703437

Title: Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association.

PubMed ID: 15703437

DOI: 10.1261/rna.7215305

PubMed ID: 20068067

Title: The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways.

PubMed ID: 20068067

DOI: 10.1158/1541-7786.mcr-08-0491

PubMed ID: 16766523

Title: Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.

PubMed ID: 16766523

DOI: 10.1074/jbc.m605418200

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17322308

Title: Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

PubMed ID: 17322308

DOI: 10.1074/mcp.m600399-mcp200

PubMed ID: 18599441

Title: Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

PubMed ID: 18599441

DOI: 10.1073/pnas.0801313105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26100019

Title: The DHX33 RNA Helicase Promotes mRNA Translation Initiation.

PubMed ID: 26100019

DOI: 10.1128/mcb.00315-15

PubMed ID: 25849773

Title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.

PubMed ID: 25849773

DOI: 10.1038/nature14267

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27462815

Title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

PubMed ID: 27462815

DOI: 10.1038/nature18954

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16322461

Title: Structural roles for human translation factor eIF3 in initiation of protein synthesis.

PubMed ID: 16322461

DOI: 10.1126/science.1118977

Sequence Information:

  • Length: 352
  • Mass: 39930
  • Checksum: F3A6EFA0CEF587D0
  • Sequence:
    • MASRKEGTGS TATSSSSTAG AAGKGKGKGG SGDSAVKQVQ IDGLVVLKII KHYQEEGQGT 
EVVQGVLLGL VVEDRLEITN CFPFPQHTED DADFDEVQYQ MEMMRSLRHV NIDHLHVGWY 
QSTYYGSFVT RALLDSQFSY QHAIEESVVL IYDPIKTAQG SLSLKAYRLT PKLMEVCKEK 
DFSPEALKKA NITFEYMFEE VPIVIKNSHL INVLMWELEK KSAVADKHEL LSLASSNHLG 
KNLQLLMDRV DEMSQDIVKY NTYMRNTSKQ QQQKHQYQQR RQQENMQRQS RGEPPLPEED 
LSKLFKPPQP PARMDSLLIA GQINTYCQNI KEFTAQNLGK LFMAQALQEY NN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.