Details for: ADAM15

Gene ID: 8751

Symbol: ADAM15

Ensembl ID: ENSG00000143537

Description: ADAM metallopeptidase domain 15

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 162.7822
    Cell Significance Index: -25.3200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 98.4453
    Cell Significance Index: -24.9700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 59.3467
    Cell Significance Index: -24.1100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 54.9588
    Cell Significance Index: -28.2700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 25.4100
    Cell Significance Index: -24.2600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.7121
    Cell Significance Index: -26.7700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.6096
    Cell Significance Index: -23.2200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.5343
    Cell Significance Index: -28.2200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.9031
    Cell Significance Index: -27.2400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 3.2736
    Cell Significance Index: 37.1900
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 2.0448
    Cell Significance Index: 4.6100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.8915
    Cell Significance Index: 33.4300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.6656
    Cell Significance Index: 86.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2038
    Cell Significance Index: 195.7900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0789
    Cell Significance Index: 64.7700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0617
    Cell Significance Index: 15.2700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0236
    Cell Significance Index: 924.1900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9289
    Cell Significance Index: 25.9600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.9216
    Cell Significance Index: 65.1800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8645
    Cell Significance Index: 18.7300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.7061
    Cell Significance Index: 32.9200
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.6990
    Cell Significance Index: 5.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6899
    Cell Significance Index: 47.7100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6622
    Cell Significance Index: 292.7700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5987
    Cell Significance Index: 326.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5432
    Cell Significance Index: 24.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5349
    Cell Significance Index: 15.4100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4469
    Cell Significance Index: 57.7400
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.4448
    Cell Significance Index: 2.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4260
    Cell Significance Index: 20.0200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3862
    Cell Significance Index: 38.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3052
    Cell Significance Index: 61.2300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2861
    Cell Significance Index: 197.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2687
    Cell Significance Index: 51.1300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2498
    Cell Significance Index: 7.3400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.2251
    Cell Significance Index: 1.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2165
    Cell Significance Index: 39.0300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2142
    Cell Significance Index: 26.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2033
    Cell Significance Index: 15.1500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1695
    Cell Significance Index: 60.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1372
    Cell Significance Index: 3.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1241
    Cell Significance Index: 4.3600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1019
    Cell Significance Index: 2.1700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0805
    Cell Significance Index: 11.0500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0552
    Cell Significance Index: 1.0200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0533
    Cell Significance Index: 10.5800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0431
    Cell Significance Index: 2.2400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0184
    Cell Significance Index: 2.3600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0046
    Cell Significance Index: 7.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0019
    Cell Significance Index: 3.5000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0000
    Cell Significance Index: -0.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0014
    Cell Significance Index: -1.0700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0067
    Cell Significance Index: -0.1000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0189
    Cell Significance Index: -25.7300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0312
    Cell Significance Index: -19.8000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0319
    Cell Significance Index: -23.4000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0359
    Cell Significance Index: -0.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0362
    Cell Significance Index: -26.8400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0483
    Cell Significance Index: -21.9100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0485
    Cell Significance Index: -8.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0492
    Cell Significance Index: -27.7700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0506
    Cell Significance Index: -31.6200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0528
    Cell Significance Index: -1.4100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0533
    Cell Significance Index: -5.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0789
    Cell Significance Index: -22.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0854
    Cell Significance Index: -9.9500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0989
    Cell Significance Index: -11.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1056
    Cell Significance Index: -15.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1062
    Cell Significance Index: -2.8900
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.1123
    Cell Significance Index: -0.7000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1246
    Cell Significance Index: -14.6900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1349
    Cell Significance Index: -1.8400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1495
    Cell Significance Index: -31.4900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1509
    Cell Significance Index: -9.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1586
    Cell Significance Index: -5.0800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1821
    Cell Significance Index: -11.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1961
    Cell Significance Index: -15.0500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2544
    Cell Significance Index: -26.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2638
    Cell Significance Index: -17.7400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3158
    Cell Significance Index: -16.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3169
    Cell Significance Index: -19.4300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3372
    Cell Significance Index: -26.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3578
    Cell Significance Index: -22.0000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4228
    Cell Significance Index: -18.7000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4359
    Cell Significance Index: -24.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5033
    Cell Significance Index: -19.0600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5131
    Cell Significance Index: -4.7300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5854
    Cell Significance Index: -21.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5937
    Cell Significance Index: -20.6300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6026
    Cell Significance Index: -12.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.6049
    Cell Significance Index: -30.5700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6112
    Cell Significance Index: -21.4100
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.6136
    Cell Significance Index: -6.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6261
    Cell Significance Index: -19.9400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6340
    Cell Significance Index: -18.6800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.6414
    Cell Significance Index: -9.1300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.6466
    Cell Significance Index: -18.5400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6863
    Cell Significance Index: -22.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.7064
    Cell Significance Index: -16.3200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.7096
    Cell Significance Index: -20.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ADAM15 exhibits characteristics of a multifunctional protein, with a metalloprotease domain capable of cleaving various substrates, including proteins and extracellular matrix components. The gene is highly expressed in endothelial cells, where it is involved in angiogenesis and vascular homeostasis. ADAM15 also plays a role in the regulation of cell growth, migration, and adhesion, and is implicated in the pathogenesis of various diseases, including cancer and cardiovascular disorders. **Pathways and Functions:** ADAM15 is involved in numerous biological pathways, including: 1. **Angiogenesis:** ADAM15 is implicated in the formation of new blood vessels, a process crucial for tissue growth and development. 2. **Cell-Matrix Adhesion:** ADAM15 regulates cell adhesion to the extracellular matrix, a process essential for cell migration, proliferation, and differentiation. 3. **Apoptotic Process:** ADAM15 is involved in the regulation of apoptosis, or programmed cell death, which is essential for tissue homeostasis and development. 4. **Immune Response:** ADAM15 is expressed on the surface of immune cells, where it regulates immune cell interactions and responses to pathogens. 5. **Extracellular Matrix Organization:** ADAM15 cleaves and regulates the structure of the extracellular matrix, which is essential for tissue homeostasis and development. **Clinical Significance:** ADAM15 has been implicated in various diseases, including: 1. **Cancer:** ADAM15 is overexpressed in several types of cancer, including breast, lung, and colon cancer, and is associated with tumor progression and metastasis. 2. **Cardiovascular Disorders:** ADAM15 is involved in the development of cardiovascular diseases, including atherosclerosis and hypertension. 3. **Neurological Disorders:** ADAM15 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Immune Disorders:** ADAM15 is involved in the regulation of immune responses, and its dysregulation can lead to autoimmune diseases. In conclusion, ADAM15 is a complex gene that plays a multifaceted role in various biological processes, including angiogenesis, cell-matrix adhesion, apoptosis, and immune response. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the functions and clinical significance of ADAM15.

Genular Protein ID: 2107396208

Symbol: ADA15_HUMAN

Name: Disintegrin and metalloproteinase domain-containing protein 15

UniProtKB Accession Codes:

Q13444 B3KQU5 B4DLB5 B4DMH8 E9PN65 Q13493 Q53XQ0 Q5SR68 Q5SR69 Q6R267 Q71S61 Q71S62 Q71S63 Q71S64 Q71S65 Q71S66 Q71S67 Q71S68 Q71S69 Q96C78 U3KQL5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 9 CDD 1 CORUM 1 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 ELM 1 EMBL 30 Ensembl 12 GO 30 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 12 Pumba 1 RNAct 1 Reactome 2 RefSeq 9 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8617717

Title: Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence.

PubMed ID: 8617717

DOI: 10.1074/jbc.271.9.4593

PubMed ID: 9039960

Title: Expression of a disintegrin-like protein in cultured human vascular cells and in vivo.

PubMed ID: 9039960

DOI: 10.1096/fasebj.11.2.9039960

PubMed ID: 15358598

Title: ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers.

PubMed ID: 15358598

DOI: 10.1152/ajpgi.00262.2004

PubMed ID: 17937806

Title: ADAM15 gene structure and differential alternative exon use in human tissues.

PubMed ID: 17937806

DOI: 10.1186/1471-2199-8-90

PubMed ID: 18296648

Title: Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma.

PubMed ID: 18296648

DOI: 10.1158/1541-7786.mcr-07-2028

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9016778

Title: Expression of members of a novel membrane linked metalloproteinase family (ADAM) in human articular chondrocytes.

PubMed ID: 9016778

DOI: 10.1006/bbrc.1996.5957

PubMed ID: 9516430

Title: Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3.

PubMed ID: 9516430

DOI: 10.1074/jbc.273.13.7345

PubMed ID: 10531379

Title: Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.

PubMed ID: 10531379

DOI: 10.1074/jbc.274.44.31693

PubMed ID: 9914169

Title: Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells.

PubMed ID: 9914169

DOI: 10.1242/jcs.112.4.579

PubMed ID: 12243749

Title: ADAM15 is an adherens junction molecule whose surface expression can be driven by VE-cadherin.

PubMed ID: 12243749

DOI: 10.1006/excr.2002.5606

PubMed ID: 11741929

Title: Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases.

PubMed ID: 11741929

DOI: 10.1074/jbc.m107430200

PubMed ID: 12091380

Title: The role of ADAM 15 in glomerular mesangial cell migration.

PubMed ID: 12091380

DOI: 10.1074/jbc.m200988200

PubMed ID: 12615925

Title: The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.

PubMed ID: 12615925

DOI: 10.1074/jbc.m300267200

PubMed ID: 15818704

Title: Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.

PubMed ID: 15818704

DOI: 10.1002/art.20974

PubMed ID: 17575078

Title: Inhibition of airway smooth muscle adhesion and migration by the disintegrin domain of ADAM-15.

PubMed ID: 17575078

DOI: 10.1165/rcmb.2006-0364oc

PubMed ID: 17416588

Title: ADAM-15/metargidin mediates homotypic aggregation of human T lymphocytes and heterotypic interactions of T lymphocytes with intestinal epithelial cells.

PubMed ID: 17416588

DOI: 10.1074/jbc.m700158200

PubMed ID: 18387333

Title: ADAM15 suppresses cell motility by driving integrin alpha5beta1 cell surface expression via Erk inactivation.

PubMed ID: 18387333

DOI: 10.1016/j.biocel.2008.02.021

PubMed ID: 18434311

Title: The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation.

PubMed ID: 18434311

DOI: 10.1074/jbc.m801329200

PubMed ID: 19207106

Title: Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.

PubMed ID: 19207106

DOI: 10.1042/bj20082127

PubMed ID: 19718658

Title: Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins.

PubMed ID: 19718658

DOI: 10.1002/jcb.22317

Sequence Information:

  • Length: 863
  • Mass: 92959
  • Checksum: 004936E9182629CA
  • Sequence:
    • MRLALLWALG LLGAGSPLPS WPLPNIGGTE EQQAESEKAP REPLEPQVLQ DDLPISLKKV 
LQTSLPEPLR IKLELDGDSH ILELLQNREL VPGRPTLVWY QPDGTRVVSE GHTLENCCYQ 
GRVRGYAGSW VSICTCSGLR GLVVLTPERS YTLEQGPGDL QGPPIISRIQ DLHLPGHTCA 
LSWRESVHTQ KPPEHPLGQR HIRRRRDVVT ETKTVELVIV ADHSEAQKYR DFQHLLNRTL 
EVALLLDTFF RPLNVRVALV GLEAWTQRDL VEISPNPAVT LENFLHWRRA HLLPRLPHDS 
AQLVTGTSFS GPTVGMAIQN SICSPDFSGG VNMDHSTSIL GVASSIAHEL GHSLGLDHDL 
PGNSCPCPGP APAKTCIMEA STDFLPGLNF SNCSRRALEK ALLDGMGSCL FERLPSLPPM 
AAFCGNMFVE PGEQCDCGFL DDCVDPCCDS LTCQLRPGAQ CASDGPCCQN CQLRPSGWQC 
RPTRGDCDLP EFCPGDSSQC PPDVSLGDGE PCAGGQAVCM HGRCASYAQQ CQSLWGPGAQ 
PAAPLCLQTA NTRGNAFGSC GRNPSGSYVS CTPRDAICGQ LQCQTGRTQP LLGSIRDLLW 
ETIDVNGTEL NCSWVHLDLG SDVAQPLLTL PGTACGPGLV CIDHRCQRVD LLGAQECRSK 
CHGHGVCDSN RHCYCEEGWA PPDCTTQLKA TSSLTTGLLL SLLVLLVLVM LGASYWYRAR 
LHQRLCQLKG PTCQYRAAQS GPSERPGPPQ RALLARGTKQ ASALSFPAPP SRPLPPDPVS 
KRLQAELADR PNPPTRPLPA DPVVRSPKSQ GPAKPPPPRK PLPADPQGRC PSGDLPGPGA 
GIPPLVVPSR PAPPPPTVSS LYL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.