Details for: RIOK3

Gene ID: 8780

Symbol: RIOK3

Ensembl ID: ENSG00000101782

Description: RIO kinase 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 295.4768
    Cell Significance Index: -45.9600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 198.5071
    Cell Significance Index: -50.3500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 143.2949
    Cell Significance Index: -59.0300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 120.5619
    Cell Significance Index: -56.9200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 117.4502
    Cell Significance Index: -47.7200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 106.0878
    Cell Significance Index: -54.5700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 85.0792
    Cell Significance Index: -57.0900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 50.5634
    Cell Significance Index: -48.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 34.7701
    Cell Significance Index: -42.8700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.2362
    Cell Significance Index: -54.2100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.6086
    Cell Significance Index: -53.7000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.1078
    Cell Significance Index: -40.2600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.5593
    Cell Significance Index: -23.1100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 7.3908
    Cell Significance Index: 121.7900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.9799
    Cell Significance Index: 135.0700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.9173
    Cell Significance Index: 99.6000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6613
    Cell Significance Index: 44.3600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.3766
    Cell Significance Index: 38.4700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2922
    Cell Significance Index: 259.2100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.2267
    Cell Significance Index: 33.3900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0654
    Cell Significance Index: 105.3900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.0161
    Cell Significance Index: 18.7800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0125
    Cell Significance Index: 65.3200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0086
    Cell Significance Index: 124.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9435
    Cell Significance Index: 27.1900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.9227
    Cell Significance Index: 166.3300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.8978
    Cell Significance Index: 490.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8709
    Cell Significance Index: 172.8300
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.8079
    Cell Significance Index: 12.2700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.8030
    Cell Significance Index: 41.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.7832
    Cell Significance Index: 36.5200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7639
    Cell Significance Index: 104.9100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7432
    Cell Significance Index: 57.0400
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.6373
    Cell Significance Index: 3.9600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6317
    Cell Significance Index: 279.2700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.5748
    Cell Significance Index: 27.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5408
    Cell Significance Index: 193.9900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5106
    Cell Significance Index: 461.0500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4968
    Cell Significance Index: 4.5800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4966
    Cell Significance Index: 80.7700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.4517
    Cell Significance Index: 53.2700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4437
    Cell Significance Index: 8.6600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4221
    Cell Significance Index: 12.1000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4046
    Cell Significance Index: 44.0100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.3758
    Cell Significance Index: 42.9000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.3350
    Cell Significance Index: 5.0200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.3309
    Cell Significance Index: 4.7100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2882
    Cell Significance Index: 4.8500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2852
    Cell Significance Index: 525.9400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2585
    Cell Significance Index: 178.8100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2402
    Cell Significance Index: 369.7200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2344
    Cell Significance Index: 44.6000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1705
    Cell Significance Index: 19.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1596
    Cell Significance Index: 300.5500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1461
    Cell Significance Index: 24.9500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0882
    Cell Significance Index: 5.4200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0622
    Cell Significance Index: 4.4000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0525
    Cell Significance Index: 33.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0519
    Cell Significance Index: 70.5100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0456
    Cell Significance Index: 20.7000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0311
    Cell Significance Index: 3.9900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0278
    Cell Significance Index: 3.6000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0102
    Cell Significance Index: 0.6400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0083
    Cell Significance Index: -0.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0221
    Cell Significance Index: -16.2000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0257
    Cell Significance Index: -19.0300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0265
    Cell Significance Index: -0.1600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0410
    Cell Significance Index: -25.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0427
    Cell Significance Index: -3.1800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0428
    Cell Significance Index: -32.4100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0548
    Cell Significance Index: -30.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0890
    Cell Significance Index: -9.1000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0930
    Cell Significance Index: -1.9800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1445
    Cell Significance Index: -30.4400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1588
    Cell Significance Index: -45.6800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1605
    Cell Significance Index: -2.1900
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.1641
    Cell Significance Index: -0.3700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1721
    Cell Significance Index: -11.9100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1807
    Cell Significance Index: -26.2700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1853
    Cell Significance Index: -10.4000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1961
    Cell Significance Index: -5.2600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2572
    Cell Significance Index: -6.6100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2633
    Cell Significance Index: -30.6800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3226
    Cell Significance Index: -6.9900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3628
    Cell Significance Index: -9.5400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4065
    Cell Significance Index: -20.5400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4159
    Cell Significance Index: -43.3100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4161
    Cell Significance Index: -27.9800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4208
    Cell Significance Index: -10.5200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4591
    Cell Significance Index: -12.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5100
    Cell Significance Index: -8.7400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5200
    Cell Significance Index: -27.3000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5298
    Cell Significance Index: -7.8200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5453
    Cell Significance Index: -8.0500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5461
    Cell Significance Index: -43.2500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6050
    Cell Significance Index: -26.7600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6364
    Cell Significance Index: -18.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7759
    Cell Significance Index: -29.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7938
    Cell Significance Index: -48.6700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8120
    Cell Significance Index: -18.7600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RIOK3 is a serine/threonine kinase gene that belongs to the RIO kinase family. The gene's protein product, RIOK3, is a non-receptor tyrosine kinase that phosphorylates and regulates various downstream targets. RIOK3 is characterized by its ability to bind to specific DNA sequences and regulate gene expression, as well as its involvement in various signaling pathways, including the NF-κB and mTOR pathways. The gene's expression is tissue-specific, with high levels of expression in epithelial cells and low levels in hematopoietic cells. **Pathways and Functions** RIOK3 is involved in a wide range of cellular processes, including: 1. **Cellular response to DNA damage**: RIOK3 is activated in response to DNA damage and regulates the expression of genes involved in DNA repair and cell cycle arrest. 2. **Innate immune response**: RIOK3 plays a critical role in regulating innate immune responses, particularly in the context of viral infections. The gene's expression is induced in response to viral infections and regulates the production of interferon-β and other cytokines. 3. **RNA metabolism**: RIOK3 is involved in the regulation of RNA processing, including the maturation of small nuclear RNAs (snRNAs) and the processing of ribosomal RNAs (rRNAs). 4. **Signal transduction**: RIOK3 is a non-receptor tyrosine kinase that phosphorylates and regulates various downstream targets, including transcription factors and other kinases. **Clinical Significance** Dysregulation of RIOK3 has been implicated in various diseases, including: 1. **Cancer**: RIOK3 is overexpressed in several types of cancer, including breast, lung, and colon cancer. The gene's dysregulation is associated with tumorigenesis and cancer progression. 2. **Autoimmune disorders**: RIOK3 is involved in the regulation of innate immune responses and has been implicated in autoimmune disorders, including rheumatoid arthritis and lupus. 3. **Infectious diseases**: RIOK3 plays a critical role in regulating innate immune responses and has been implicated in the pathogenesis of viral infections, including HIV and influenza. In conclusion, RIOK3 is a critical gene that regulates various cellular processes, including signal transduction, DNA damage response, and RNA metabolism. The gene's dysregulation has been implicated in various diseases, including cancer, autoimmune disorders, and infectious diseases. Further research is needed to fully understand the role of RIOK3 in human disease and to develop therapeutic strategies to target this gene.

Genular Protein ID: 2865794690

Symbol: RIOK3_HUMAN

Name: Serine/threonine-protein kinase RIO3

UniProtKB Accession Codes:

O14730 Q8IXN9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 3 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9602165

Title: Isolation of the Aspergillus nidulans sudD gene and its human homologue.

PubMed ID: 9602165

DOI: 10.1016/s0378-1119(98)00115-2

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19557502

Title: RIOK3 interacts with caspase-10 and negatively regulates the NF-kappaB signaling pathway.

PubMed ID: 19557502

DOI: 10.1007/s11010-009-0180-8

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22072790

Title: The kinase activity of human Rio1 is required for final steps of cytoplasmic maturation of 40S subunits.

PubMed ID: 22072790

DOI: 10.1091/mbc.e11-07-0639

PubMed ID: 22418843

Title: Human RioK3 is a novel component of cytoplasmic pre-40S pre-ribosomal particles.

PubMed ID: 22418843

DOI: 10.4161/rna.18810

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24807708

Title: RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production.

PubMed ID: 24807708

DOI: 10.1128/jvi.00643-14

PubMed ID: 25865883

Title: RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response.

PubMed ID: 25865883

DOI: 10.1016/j.celrep.2015.03.027

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 519
  • Mass: 59093
  • Checksum: 3C3392BAC4ECB912
  • Sequence:
    • MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA 
VAEGPFITGE NIDTSSDLML AQMLQMEYDR EYDAQLRREE KKFNGDSKVS ISFENYRKVH 
PYEDSDSSED EVDWQDTRDD PYRPAKPVPT PKKGFIGKGK DITTKHDEVV CGRKNTARME 
NFAPEFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL 
MYKMVNSGML ETITGCISTG KESVVFHAYG GSMEDEKEDS KVIPTECAIK VFKTTLNEFK 
NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLARMQ RAGIPCPTVV LLKKHILVMS 
FIGHDQVPAP KLKEVKLNSE EMKEAYYQTL HLMRQLYHEC TLVHADLSEY NMLWHAGKVW 
LIDVSQSVEP THPHGLEFLF RDCRNVSQFF QKGGVKEALS ERELFNAVSG LNITADNEAD 
FLAEIEALEK MNEDHVQKNG RKAASFLKDD GDPPLLYDE

Genular Protein ID: 2822344091

Symbol: B4E1Q4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E1Q4

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 11 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 3 Ensembl 2 GO 5 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 6 SAM 1 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 503
  • Mass: 57474
  • Checksum: 2BA1496AE8A3A64E
  • Sequence:
    • MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA 
DLMLAQMLQM EYDREYDAQL RREEKKFNGD SKVSISFENY RKVHPYEDSD SSEDEVDWQD 
TRDDPYRPAK PVPTPKKGFI GKGKDITTKH DEVVCGRKNT ARMENFAPEF QVGDGIGMDL 
KLSNHVFNAL KQHAYSEERR SARLHEKKEH STAEKAVDPK TRLLMYKMVN SGMLETITGC 
ISTGKESVVF HAYGGSMEDE KEDSKVIPTE CAIKVFKTTL NEFKNRDKYI KDDFRFKDRF 
SKLNPRKIIR MWAEKEMHNL ARMQRAGIPC PTVVLLKKHI LVMSFIGHDQ VPAPKLKEVK 
LNSEEMKEAY YQTLHLMRQL YHECTLVHAD LSEYNMLWHA GKVWLIDVSQ SVEPTHPHGL 
EFLFRDCRNV SQFFQKGGVK EALSERELFN AVSGLNITAD NEADFLAEIE ALEKMNEDHV 
QKNGRKAASF LKDDGDPPLL YDE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.