Details for: MAGI1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: photoreceptor cell (CL0000210)
Fold Change: 5.97
Marker Score: 4,497 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 5.23
Marker Score: 21,791 - Cell Name: hepatoblast (CL0005026)
Fold Change: 5.09
Marker Score: 16,674 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 5.07
Marker Score: 113,409 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 4.93
Marker Score: 4,263 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 4.83
Marker Score: 4,282 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 4.82
Marker Score: 16,172 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 4.74
Marker Score: 3,289 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 4.4
Marker Score: 4,988 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 4.38
Marker Score: 5,895 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 4.24
Marker Score: 19,626 - Cell Name: stellate neuron (CL0000122)
Fold Change: 4.21
Marker Score: 22,596 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 4.2
Marker Score: 1,535 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 4.16
Marker Score: 5,033 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 4.03
Marker Score: 71,587 - Cell Name: renal principal cell (CL0005009)
Fold Change: 3.81
Marker Score: 2,934 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 3.81
Marker Score: 128,608 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 3.57
Marker Score: 8,540 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 3.46
Marker Score: 1,820 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 3.44
Marker Score: 12,245 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 3.42
Marker Score: 14,301 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 3.25
Marker Score: 950 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 3.19
Marker Score: 1,533 - Cell Name: contractile cell (CL0000183)
Fold Change: 3.16
Marker Score: 1,710 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 3.15
Marker Score: 907 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 3.11
Marker Score: 4,520 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 3.03
Marker Score: 2,893 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.97
Marker Score: 943 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.93
Marker Score: 1,641 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.91
Marker Score: 6,690 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.87
Marker Score: 46,147 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.87
Marker Score: 57,156 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.81
Marker Score: 1,636 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.77
Marker Score: 41,458 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.75
Marker Score: 6,045 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.74
Marker Score: 1,604 - Cell Name: endocrine cell (CL0000163)
Fold Change: 2.74
Marker Score: 1,417 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.74
Marker Score: 20,990 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.74
Marker Score: 5,267 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.68
Marker Score: 101,915 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.67
Marker Score: 57,011 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2.65
Marker Score: 2,862 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 2.59
Marker Score: 2,771 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.58
Marker Score: 10,699 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.57
Marker Score: 1,077 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 2.57
Marker Score: 1,342 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.55
Marker Score: 7,277 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.53
Marker Score: 1,512 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.49
Marker Score: 785 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2.48
Marker Score: 1,631 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.47
Marker Score: 1,433 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.45
Marker Score: 90,414 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 2.43
Marker Score: 8,620 - Cell Name: fat cell (CL0000136)
Fold Change: 2.38
Marker Score: 1,328 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 2.38
Marker Score: 863 - Cell Name: acinar cell (CL0000622)
Fold Change: 2.34
Marker Score: 1,648 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.33
Marker Score: 8,994 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.31
Marker Score: 3,877 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.29
Marker Score: 879 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.21
Marker Score: 2,440 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.19
Marker Score: 20,557 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 2.18
Marker Score: 2,260 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.17
Marker Score: 2,495 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.07
Marker Score: 127,023 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.06
Marker Score: 2,553 - Cell Name: astrocyte (CL0000127)
Fold Change: 2.01
Marker Score: 1,740 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2
Marker Score: 20,635 - Cell Name: neuron (CL0000540)
Fold Change: 1.97
Marker Score: 8,015 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.96
Marker Score: 622 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.96
Marker Score: 739 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.93
Marker Score: 528 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 1.93
Marker Score: 853 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.92
Marker Score: 10,304 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.91
Marker Score: 18,162 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.91
Marker Score: 2,700 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.87
Marker Score: 477 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.87
Marker Score: 2,334 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.85
Marker Score: 15,931 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.85
Marker Score: 1,521 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 1.82
Marker Score: 500 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.81
Marker Score: 677 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.76
Marker Score: 2,126 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.76
Marker Score: 2,475 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 1.73
Marker Score: 458 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.72
Marker Score: 11,089 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.69
Marker Score: 2,104 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.68
Marker Score: 527 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.67
Marker Score: 3,940 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.63
Marker Score: 2,518 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.63
Marker Score: 906 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.61
Marker Score: 6,939 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.59
Marker Score: 785 - Cell Name: granule cell (CL0000120)
Fold Change: 1.58
Marker Score: 11,928 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.57
Marker Score: 8,225 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.56
Marker Score: 3,913 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.56
Marker Score: 531 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.53
Marker Score: 308 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 1.52
Marker Score: 2,524 - Cell Name: mural cell (CL0008034)
Fold Change: 1.45
Marker Score: 166,122 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.45
Marker Score: 439
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3248722423
Symbol: MAGI1_HUMAN
Name: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9647739
Title: Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.
PubMed ID: 9647739
PubMed ID: 11969287
Title: MAGI-1: a widely expressed, alternatively spliced tight junction protein.
PubMed ID: 11969287
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 9647693
Title: Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.
PubMed ID: 9647693
PubMed ID: 9169421
Title: Identification of novel human WW domain-containing proteins by cloning of ligand targets.
PubMed ID: 9169421
PubMed ID: 11168587
Title: Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions.
PubMed ID: 11168587
PubMed ID: 12042308
Title: Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1.
PubMed ID: 12042308
PubMed ID: 12773569
Title: JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1.
PubMed ID: 12773569
PubMed ID: 14627983
Title: Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.
PubMed ID: 14627983
PubMed ID: 15317815
Title: PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current.
PubMed ID: 15317815
PubMed ID: 16043488
Title: Angiomotin regulates endothelial cell-cell junctions and cell motility.
PubMed ID: 16043488
PubMed ID: 16751601
Title: CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin.
PubMed ID: 16751601
DOI: 10.1093/jb/mvj105
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23873930
Title: Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.
PubMed ID: 23873930
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24561201
Title: Mislocalization of K+ channels causes the renal salt wasting in EAST/SeSAME syndrome.
PubMed ID: 24561201
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1491
- Mass: 164581
- Checksum: 4B2EE05243A6FA65
- Sequence:
MSKVIQKKNH WTSRVHECTV KRGPQGELGV TVLGGAEHGE FPYVGAVAAV EAAGLPGGGE GPRLGEGELL LEVQGVRVSG LPRYDVLGVI DSCKEAVTFK AVRQGGRLNK DLRHFLNQRF QKGSPDHELQ QTIRDNLYRH AVPCTTRSPR EGEVPGVDYN FLTVKEFLDL EQSGTLLEVG TYEGNYYGTP KPPSQPVSGK VITTDALHSL QSGSKQSTPK RTKSYNDMQN AGIVHAENEE EDDVPEMNSS FTADSGEQEE HTLQETALPP VNSSIIAAPI TDPSQKFPQY LPLSAEDNLG PLPENWEMAY TENGEVYFID HNTKTTSWLD PRCLNKQQKP LEECEDDEGV HTEELDSELE LPAGWEKIED PVYGIYYVDH INRKTQYENP VLEAKRKKQL EQQQQQQQQQ QQQQQQQQQQ QTEEWTEDHS ALVPPVIPNH PPSNPEPARE VPLQGKPFFT RNPSELKGKF IHTKLRKSSR GFGFTVVGGD EPDEFLQIKS LVLDGPAALD GKMETGDVIV SVNDTCVLGH THAQVVKIFQ SIPIGASVDL ELCRGYPLPF DPDDPNTSLV TSVAILDKEP IIVNGQETYD SPASHSSKTG KVNGMKDARP SSPADVASNS SHGYPNDTVS LASSIATQPE LITVHIVKGP MGFGFTIADS PGGGGQRVKQ IVDSPRCRGL KEGDLIVEVN KKNVQALTHN QVVDMLVECP KGSEVTLLVQ RGGLPVPKKS PKSQPLERKD SQNSSQHSVS SHRSLHTASP SHSTQVLPEF PPAEAQAPDQ TDSSGQKKPD PFKIWAQSRS MYENRPMSPS PASGLSKGER EREINSTNFG ECPIPDYQEQ DIFLWRKETG FGFRILGGNE PGEPIYIGHI VPLGAADTDG RLRSGDELIC VDGTPVIGKS HQLVVQLMQQ AAKQGHVNLT VRRKVVFAVP KTENEVPSPA SSHHSSNQPA SLTEEKRTPQ GSQNSLNTVS SGSGSTSGIG SGGGGGSGVV STVVQPYDVE IRRGENEGFG FVIVSSVSRP EAGTTFAGNA CVAMPHKIGR IIEGSPADRC GKLKVGDRIL AVNGCSITNK SHSDIVNLIK EAGNTVTLRI IPGDESSNAT LLTNAEKIAT ITTTHTPSQQ GTQETRNTTK PKQESQFEFK APQATQEQDF YTVELERGAK GFGFSLRGGR EYNMDLYVLR LAEDGPAERC GKMRIGDEIL EINGETTKNM KHSRAIELIK NGGRRVRLFL KRGDGSVPEY DPSSDRHGPA TGPQGVPEVR AGPDRRQHPS LESSYPPDLH KSSPHGEKRA HARDPKGSRE YSRQPNEHHT WNGTSRKPDS GACRPKDRAP EGRRDAQAER AAAANGPKRR SPEKRREGTR SADNTLERRE KHEKRRDVSP ERRRERSPTR RRDGSPSRRR RSLERLLEQR RSPERRRGGS PERRAKSTDR RRARSPERRR ERSLDKRNRE DRASHREREE ANLKQDAGRS SRHPPEQRRR PYKECSTDLS I
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.