Details for: OSTN AS1

Gene ID: 106480738

Symbol: OSTN AS1

Ensembl ID: ENSG00000233308

Description: OSTN antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.8298
    Cell Significance Index: 20.1000
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.3406
    Cell Significance Index: 4.3100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.2733
    Cell Significance Index: 8.0500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0785
    Cell Significance Index: 1.3200
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0605
    Cell Significance Index: 0.8400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0526
    Cell Significance Index: 1.4100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.0274
    Cell Significance Index: 0.3800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0201
    Cell Significance Index: 0.4400
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.0177
    Cell Significance Index: 0.1800
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.0174
    Cell Significance Index: 0.2100
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.0116
    Cell Significance Index: 0.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0094
    Cell Significance Index: 0.9600
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.0058
    Cell Significance Index: 0.0600
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.0053
    Cell Significance Index: 0.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0017
    Cell Significance Index: 0.3300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0011
    Cell Significance Index: 0.1300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0005
    Cell Significance Index: 0.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0002
    Cell Significance Index: 0.3100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0003
    Cell Significance Index: -0.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0004
    Cell Significance Index: -0.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.8500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0006
    Cell Significance Index: -0.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0007
    Cell Significance Index: -0.9300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0009
    Cell Significance Index: -0.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0011
    Cell Significance Index: -0.8200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0012
    Cell Significance Index: -0.7900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0015
    Cell Significance Index: -0.0400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0019
    Cell Significance Index: -0.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0024
    Cell Significance Index: -0.6900
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0029
    Cell Significance Index: -0.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0036
    Cell Significance Index: -0.5300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0036
    Cell Significance Index: -0.6200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0041
    Cell Significance Index: -0.7400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0046
    Cell Significance Index: -0.6300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0049
    Cell Significance Index: -0.6000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0054
    Cell Significance Index: -0.6200
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0056
    Cell Significance Index: -0.0700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0070
    Cell Significance Index: -0.1000
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0074
    Cell Significance Index: -0.0900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0077
    Cell Significance Index: -0.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0079
    Cell Significance Index: -0.8200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0088
    Cell Significance Index: -0.4100
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0095
    Cell Significance Index: -0.1100
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0103
    Cell Significance Index: -0.1000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0103
    Cell Significance Index: -0.7900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0105
    Cell Significance Index: -0.5300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0114
    Cell Significance Index: -0.5000
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0117
    Cell Significance Index: -0.1300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0119
    Cell Significance Index: -0.7300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0122
    Cell Significance Index: -0.8200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0137
    Cell Significance Index: -0.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0157
    Cell Significance Index: -0.8800
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0158
    Cell Significance Index: -0.2700
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0164
    Cell Significance Index: -0.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0183
    Cell Significance Index: -0.8600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0185
    Cell Significance Index: -0.5900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0199
    Cell Significance Index: -0.6500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0201
    Cell Significance Index: -0.8900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0204
    Cell Significance Index: -0.7500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0226
    Cell Significance Index: -0.2400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0229
    Cell Significance Index: -0.4800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0235
    Cell Significance Index: -0.8900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0244
    Cell Significance Index: -0.3500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0247
    Cell Significance Index: -0.6200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0251
    Cell Significance Index: -0.6700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0257
    Cell Significance Index: -0.4400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0259
    Cell Significance Index: -0.5500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0264
    Cell Significance Index: -0.6100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0269
    Cell Significance Index: -1.1000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0273
    Cell Significance Index: -0.5100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0277
    Cell Significance Index: -0.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0280
    Cell Significance Index: -0.7500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0280
    Cell Significance Index: -0.4500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0286
    Cell Significance Index: -0.5000
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0288
    Cell Significance Index: -0.4200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0289
    Cell Significance Index: -0.5800
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0296
    Cell Significance Index: -0.3600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0310
    Cell Significance Index: -0.7900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0311
    Cell Significance Index: -0.7500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0313
    Cell Significance Index: -0.8000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0314
    Cell Significance Index: -0.9000
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0318
    Cell Significance Index: -0.5400
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0319
    Cell Significance Index: -0.3600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0321
    Cell Significance Index: -0.6700
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0321
    Cell Significance Index: -0.4500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0328
    Cell Significance Index: -0.3400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0329
    Cell Significance Index: -0.7100
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0336
    Cell Significance Index: -0.5100
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0340
    Cell Significance Index: -0.6700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0354
    Cell Significance Index: -0.7000
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.0354
    Cell Significance Index: -0.5700
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0362
    Cell Significance Index: -0.4400
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0369
    Cell Significance Index: -0.5100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0375
    Cell Significance Index: -0.9400
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0390
    Cell Significance Index: -0.5300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0390
    Cell Significance Index: -0.5200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0401
    Cell Significance Index: -0.8000
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0402
    Cell Significance Index: -0.4800
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0403
    Cell Significance Index: -0.5900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0407
    Cell Significance Index: -0.6000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Non-coding RNA**: OSTN AS1 is a non-coding RNA, meaning it does not encode a protein. Instead, it regulates gene expression through various mechanisms, including RNA interference (RNAi) and microRNA (miRNA) mediated pathways. 2. **Antisense RNA**: OSTN AS1 is an antisense RNA, meaning it is transcribed from the opposite strand of the genome as a complementary RNA molecule. This allows it to regulate gene expression by interacting with its sense counterpart. 3. **Diverse tissue expression**: OSTN AS1 is expressed in various cell types, including blood vessel endothelial cells, T cells, stem cells, and epithelial cells. This suggests a broad role in regulating cellular development and immune responses. 4. **Cellular specificity**: The expression of OSTN AS1 is highly specific to certain cell types, indicating a high degree of regulation and specificity in its function. **Pathways and Functions:** 1. **Immune regulation**: OSTN AS1 has been implicated in regulating immune responses, particularly in the context of T cell development and function. It is expressed in T cells and is thought to play a role in modulating their activation and proliferation. 2. **Cellular development**: OSTN AS1 is involved in regulating cellular development, particularly in the context of stem cell biology. It is expressed in stem cells and is thought to play a role in maintaining their self-renewal and differentiation capabilities. 3. **Tissue homeostasis**: OSTN AS1 is involved in maintaining tissue homeostasis, particularly in the context of epithelial tissue. It is expressed in epithelial cells and is thought to play a role in regulating their proliferation and differentiation. 4. **RNA-mediated regulation**: OSTN AS1 regulates gene expression through RNA-mediated mechanisms, including RNAi and miRNA mediated pathways. This allows it to fine-tune gene expression in response to changing cellular conditions. **Clinical Significance:** The dysregulation of OSTN AS1 has been implicated in various diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. For example, alterations in OSTN AS1 expression have been observed in certain types of cancer, including colon cancer and lung cancer. Additionally, OSTN AS1 has been implicated in the pathogenesis of autoimmune disorders, such as multiple sclerosis and rheumatoid arthritis. Further research is needed to fully understand the role of OSTN AS1 in human disease and to develop therapeutic strategies targeting this gene. In conclusion, OSTN AS1 is a multifaceted gene involved in regulating immune responses, cellular development, and tissue homeostasis. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms underlying its function and the development of therapeutic strategies targeting this gene.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.