Details for: CD55

Gene ID: 1604

Symbol: CD55

Ensembl ID: ENSG00000196352

Description: CD55 molecule (Cromer blood group)

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 330.3219
    Cell Significance Index: -51.3800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 200.9120
    Cell Significance Index: -50.9600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 145.0184
    Cell Significance Index: -59.7400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 130.0531
    Cell Significance Index: -52.8400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 116.4422
    Cell Significance Index: -54.9800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 111.1035
    Cell Significance Index: -57.1500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 82.0390
    Cell Significance Index: -55.0500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 55.4495
    Cell Significance Index: -52.9400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 41.2261
    Cell Significance Index: -50.8300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.9189
    Cell Significance Index: -53.3600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.1027
    Cell Significance Index: -55.6500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.7980
    Cell Significance Index: -42.3800
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 10.7363
    Cell Significance Index: 31.9300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.2251
    Cell Significance Index: -20.1900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 5.1741
    Cell Significance Index: 37.1600
  • Cell Name: theca cell (CL0000503)
    Fold Change: 3.5047
    Cell Significance Index: 20.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 3.3340
    Cell Significance Index: 173.1900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.2893
    Cell Significance Index: 87.8300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.1708
    Cell Significance Index: 90.8900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.6742
    Cell Significance Index: 71.6600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.5619
    Cell Significance Index: 47.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.3356
    Cell Significance Index: 1275.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.2744
    Cell Significance Index: 65.5300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.2442
    Cell Significance Index: 105.4800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.0063
    Cell Significance Index: 18.4800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.9273
    Cell Significance Index: 87.3600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.7619
    Cell Significance Index: 82.1500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.3106
    Cell Significance Index: 23.1600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2815
    Cell Significance Index: 208.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.2693
    Cell Significance Index: 163.9900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.2413
    Cell Significance Index: 18.6000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.2131
    Cell Significance Index: 33.0200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.1679
    Cell Significance Index: 59.0200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.1556
    Cell Significance Index: 7.1800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.1004
    Cell Significance Index: 28.9400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.0867
    Cell Significance Index: 21.2100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0770
    Cell Significance Index: 147.9000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.0466
    Cell Significance Index: 24.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9725
    Cell Significance Index: 119.5800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9719
    Cell Significance Index: 58.3500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6567
    Cell Significance Index: 592.9600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.6379
    Cell Significance Index: 9.0800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5526
    Cell Significance Index: 35.6500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5378
    Cell Significance Index: 63.4200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4585
    Cell Significance Index: 11.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4497
    Cell Significance Index: 81.0700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4356
    Cell Significance Index: 43.0900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4316
    Cell Significance Index: 15.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4077
    Cell Significance Index: 180.2700
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 0.4023
    Cell Significance Index: 8.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4015
    Cell Significance Index: 27.7700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2900
    Cell Significance Index: 184.1900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2474
    Cell Significance Index: 31.7200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2248
    Cell Significance Index: 80.6300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1964
    Cell Significance Index: 15.0800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1955
    Cell Significance Index: 14.5700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1897
    Cell Significance Index: 5.5700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1337
    Cell Significance Index: 26.8200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1294
    Cell Significance Index: 97.9400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0748
    Cell Significance Index: 14.2400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0365
    Cell Significance Index: 68.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0030
    Cell Significance Index: 5.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0014
    Cell Significance Index: 2.1600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0124
    Cell Significance Index: -9.1700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0152
    Cell Significance Index: -9.4700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0157
    Cell Significance Index: -21.3700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0158
    Cell Significance Index: -0.1800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0539
    Cell Significance Index: -5.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0579
    Cell Significance Index: -42.4800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0641
    Cell Significance Index: -12.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0675
    Cell Significance Index: -38.0600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0711
    Cell Significance Index: -0.9700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0743
    Cell Significance Index: -12.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0816
    Cell Significance Index: -37.0200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1123
    Cell Significance Index: -16.3300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1358
    Cell Significance Index: -28.6000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1374
    Cell Significance Index: -16.0100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1507
    Cell Significance Index: -43.3600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1526
    Cell Significance Index: -10.7900
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.1640
    Cell Significance Index: -1.0200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.2178
    Cell Significance Index: -3.3700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2296
    Cell Significance Index: -4.8900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.2492
    Cell Significance Index: -6.0800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2740
    Cell Significance Index: -31.2800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3095
    Cell Significance Index: -6.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3333
    Cell Significance Index: -38.1900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4254
    Cell Significance Index: -22.1600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4412
    Cell Significance Index: -14.1300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5104
    Cell Significance Index: -53.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5521
    Cell Significance Index: -15.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5950
    Cell Significance Index: -40.0100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6038
    Cell Significance Index: -16.1500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6454
    Cell Significance Index: -16.5900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6683
    Cell Significance Index: -40.9700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6900
    Cell Significance Index: -54.6500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.7121
    Cell Significance Index: -43.7700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.7182
    Cell Significance Index: -40.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.8184
    Cell Significance Index: -42.9700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.9053
    Cell Significance Index: -57.0600
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.9054
    Cell Significance Index: -8.6000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** The CD55 protein is a transmembrane glycoprotein composed of four extracellular domains, which are rich in sialic acid residues. This unique structure enables the protein to interact with the complement system and other molecules. 2. **Function:** The primary function of CD55 is to regulate the activation of the complement system, specifically the classical pathway. It achieves this by accelerating the decay of complement C3b, thereby preventing excessive complement activation and subsequent tissue damage. 3. **Expression:** CD55 is widely expressed in various tissues, including epithelial cells, secretory cells, and immune cells, such as non-classical monocytes and IgG-negative class-switched memory B cells. 4. **Evolutionary Conservation:** The CD55 gene is highly conserved across species, suggesting its essential role in maintaining immune homeostasis. **Pathways and Functions:** 1. **Complement Activation:** CD55 regulates the activation of the complement system, specifically the classical pathway, by accelerating the decay of complement C3b. 2. **Cell Surface:** CD55 is a transmembrane glycoprotein, which allows it to interact with other molecules on the cell surface, including complement components and immune cells. 3. **Golgi Anterograde Transport:** CD55 undergoes anterograde transport from the endoplasmic reticulum to the Golgi apparatus, where it is modified and secreted onto the cell surface. 4. **Signaling:** CD55 can modulate signaling pathways, including the regulation of CD4-positive, alpha-beta T cell activation and proliferation. **Clinical Significance:** 1. **Complement-Related Disorders:** Mutations in the CD55 gene have been associated with complement-related disorders, such as atypical hemolytic uremic syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN). 2. **Infectious Diseases:** CD55 has been implicated in the regulation of lipopolysaccharide-mediated signaling pathways, which are critical in the response to bacterial infections. 3. **Cancer:** The expression of CD55 has been observed in various types of cancer, including lung, breast, and colon cancer, suggesting its potential role in tumorigenesis and metastasis. 4. **Viral Infections:** CD55 has been shown to regulate the entry of viruses into host cells, highlighting its importance in the defense against viral infections. In conclusion, the CD55 gene plays a crucial role in regulating the complement system and modulating immune responses. Its dysregulation has been implicated in various diseases, including complement-related disorders and infectious diseases. Further research is necessary to fully elucidate the functions and clinical significance of the CD55 gene.

Genular Protein ID: 2793829098

Symbol: DAF_HUMAN

Name: Complement decay-accelerating factor

UniProtKB Accession Codes:

P08174 B1AP14 D3DT83 D3DT84 E7ER69 P09679 P78361 Q14UF2 Q14UF3 Q14UF4 Q14UF5 Q14UF6

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 21 EMDB 13 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 32 PDBsum 32 PIR 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 4 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2433596

Title: Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins.

PubMed ID: 2433596

DOI: 10.1038/325545a0

PubMed ID: 16503113

Title: Molecular cloning and characterization of novel splicing variants of human decay-accelerating factor.

PubMed ID: 16503113

DOI: 10.1016/j.ygeno.2006.01.006

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1711208

Title: Characterization of the decay-accelerating factor gene promoter region.

PubMed ID: 1711208

DOI: 10.1073/pnas.88.11.4675

PubMed ID: 2436222

Title: Cloning and characterization of cDNAs encoding the complete sequence of decay-accelerating factor of human complement.

PubMed ID: 2436222

DOI: 10.1073/pnas.84.7.2007

PubMed ID: 2428813

Title: Improved method for the isolation and preliminary characterization of human DAF (decay-accelerating factor).

PubMed ID: 2428813

DOI: 10.1093/oxfordjournals.jbchem.a121686

PubMed ID: 1712233

Title: Isolation of two forms of decay-accelerating factor (DAF) from human urine.

PubMed ID: 1712233

DOI: 10.1016/0304-4165(91)90171-c

PubMed ID: 1824699

Title: Glycophospholipid membrane anchor attachment. Molecular analysis of the cleavage/attachment site.

PubMed ID: 1824699

DOI: 10.1016/s0021-9258(17)35308-5

PubMed ID: 1377029

Title: Complete determination of disulfide bonds localized within the short consensus repeat units of decay accelerating factor (CD55 antigen).

PubMed ID: 1377029

DOI: 10.1016/0304-4165(92)90016-n

PubMed ID: 7525274

Title: Decay-accelerating factor CD55 is identified as the receptor for echovirus 7 using CELICS, a rapid immuno-focal cloning method.

PubMed ID: 7525274

DOI: 10.1002/j.1460-2075.1994.tb06836.x

PubMed ID: 7517044

Title: Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses.

PubMed ID: 7517044

DOI: 10.1073/pnas.91.13.6245

PubMed ID: 7538177

Title: Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.

PubMed ID: 7538177

DOI: 10.1128/jvi.69.6.3873-3877.1995

PubMed ID: 8764022

Title: The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).

PubMed ID: 8764022

DOI: 10.1128/jvi.70.8.5143-5152.1996

PubMed ID: 9151867

Title: Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry.

PubMed ID: 9151867

DOI: 10.1128/jvi.71.6.4736-4743.1997

PubMed ID: 11297558

Title: Molecular analysis of the epidermal growth factor-like short consensus repeat domain-mediated protein-protein interactions: dissection of the CD97-CD55 complex.

PubMed ID: 11297558

DOI: 10.1074/jbc.m101770200

PubMed ID: 12409401

Title: Human rhinovirus 87 and enterovirus 68 represent a unique serotype with rhinovirus and enterovirus features.

PubMed ID: 12409401

DOI: 10.1128/jcm.40.11.4218-4223.2002

PubMed ID: 17804498

Title: Interaction of decay-accelerating factor with coxsackievirus B3.

PubMed ID: 17804498

DOI: 10.1128/jvi.00931-07

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 26207632

Title: Obif, a transmembrane protein, is required for bone mineralization and spermatogenesis in mice.

PubMed ID: 26207632

DOI: 10.1371/journal.pone.0133704

PubMed ID: 28657861

Title: Loss of CD55 in eculizumab-responsive protein-losing enteropathy.

PubMed ID: 28657861

DOI: 10.1056/nejmc1707173

PubMed ID: 7519480

Title: Molecular basis of reduced or absent expression of decay-accelerating factor in Cromer blood group phenotypes.

PubMed ID: 7519480

PubMed ID: 12675719

Title: GUTI: a new antigen in the Cromer blood group system.

PubMed ID: 12675719

DOI: 10.1046/j.1537-2995.2003.00319.x

PubMed ID: 1720702

Title: Biochemical studies on red blood cells from a patient with the Inab phenotype (decay-accelerating factor deficiency).

PubMed ID: 1720702

PubMed ID: 12499389

Title: Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A.

PubMed ID: 12499389

DOI: 10.1074/jbc.m212561200

PubMed ID: 14734808

Title: Complement regulation at the molecular level: the structure of decay-accelerating factor.

PubMed ID: 14734808

DOI: 10.1073/pnas.0307200101

PubMed ID: 12672958

Title: Solution structure of a functionally active fragment of decay-accelerating factor.

PubMed ID: 12672958

DOI: 10.1073/pnas.0730844100

PubMed ID: 28657829

Title: CD55 deficiency, early-onset protein-losing enteropathy, and thrombosis.

PubMed ID: 28657829

DOI: 10.1056/nejmoa1615887

Sequence Information:

  • Length: 381
  • Mass: 41400
  • Checksum: C1CBE5300F60C176
  • Sequence:
    • MTVARPSVPA ALPLLGELPR LLLLVLLCLP AVWGDCGLPP DVPNAQPALE GRTSFPEDTV 
ITYKCEESFV KIPGEKDSVI CLKGSQWSDI EEFCNRSCEV PTRLNSASLK QPYITQNYFP 
VGTVVEYECR PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI 
LFGATISFSC NTGYKLFGST SSFCLISGSS VQWSDPLPEC REIYCPAPPQ IDNGIIQGER 
DHYGYRQSVT YACNKGFTMI GEHSIYCTVN NDEGEWSGPP PECRGKSLTS KVPPTVQKPT 
TVNVPTTEVS PTSQKTTTKT TTPNAQATRS TPVSRTTKHF HETTPNKGSG TTSGTTRLLS 
GHTCFTLTGL LGTLVTMGLL T

Genular Protein ID: 943026165

Symbol: B1AP13_HUMAN

Name: N/A

UniProtKB Accession Codes:

B1AP13

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 NIAGADS 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 444
  • Mass: 49338
  • Checksum: 38B7D12413F52A23
  • Sequence:
    • MTVARPSVPA ALPLLGELPR LLLLVLLCLP AVWGDCGLPP DVPNAQPALE GRTSFPEDTV 
ITYKCEESFV KIPGEKDSVI CLKGSQWSDI EEFCNRSCEV PTRLNSASLK QPYITQNYFP 
VGTVVEYECR PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI 
LFGATISFSC NTGYKLFGST SSFCLISGSS VQWSDPLPEC REIYCPAPPQ IDNGIIQGER 
DHYGYRQSVT YACNKGFTMI GEHSIYCTVN NDEGEWSGPP PECRGKSLTS KVPPTVQKPT 
TVNVPTTEVS PTSQKTTTKT TTPNAQATRS TPVSRTTKHF HETTPNKGSG TTSGTTRLLS 
GSRPVTQAGM RWCDRSSLQS RTPGFKRSFH FSLPSSWYYR CVPRHPAKFL KFIFCRDRIF 
LCCPGWFQTP GRKRFFRPPK TLRL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.