Details for: DCX

Gene ID: 1641

Symbol: DCX

Ensembl ID: ENSG00000077279

Description: doublecortin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 4.6888
    Cell Significance Index: 112.4500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 4.6510
    Cell Significance Index: 285.8700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.6479
    Cell Significance Index: 57.9800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.1046
    Cell Significance Index: 754.8800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.5194
    Cell Significance Index: 93.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0272
    Cell Significance Index: 206.0600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.8530
    Cell Significance Index: 37.7300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.8429
    Cell Significance Index: 31.9200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7004
    Cell Significance Index: 484.4500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6531
    Cell Significance Index: 41.1700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5037
    Cell Significance Index: 95.8600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.4877
    Cell Significance Index: 15.6200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4373
    Cell Significance Index: 19.8200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2165
    Cell Significance Index: 195.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0216
    Cell Significance Index: -3.5100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0250
    Cell Significance Index: -46.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0268
    Cell Significance Index: -50.3900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0310
    Cell Significance Index: -47.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0342
    Cell Significance Index: -1.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0355
    Cell Significance Index: -48.2700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0411
    Cell Significance Index: -4.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0473
    Cell Significance Index: -35.0600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0531
    Cell Significance Index: -0.6200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0642
    Cell Significance Index: -47.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0733
    Cell Significance Index: -46.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0743
    Cell Significance Index: -41.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0833
    Cell Significance Index: -2.4000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0884
    Cell Significance Index: -55.1800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1020
    Cell Significance Index: -46.3000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1299
    Cell Significance Index: -37.3800
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.1399
    Cell Significance Index: -0.9100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1785
    Cell Significance Index: -3.5300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1908
    Cell Significance Index: -4.7700
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.2018
    Cell Significance Index: -1.9200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2354
    Cell Significance Index: -49.5900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2429
    Cell Significance Index: -26.4200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2451
    Cell Significance Index: -6.8500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2593
    Cell Significance Index: -46.7500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2601
    Cell Significance Index: -5.5200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.2690
    Cell Significance Index: -53.3900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2711
    Cell Significance Index: -2.5700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2711
    Cell Significance Index: -37.2300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3121
    Cell Significance Index: -53.3000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3186
    Cell Significance Index: -46.3100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3334
    Cell Significance Index: -43.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3445
    Cell Significance Index: -19.3300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3519
    Cell Significance Index: -41.0100
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3630
    Cell Significance Index: -9.0500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3799
    Cell Significance Index: -46.7200
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.4070
    Cell Significance Index: -3.5200
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.4128
    Cell Significance Index: -6.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.4381
    Cell Significance Index: -30.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4474
    Cell Significance Index: -20.8600
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.4545
    Cell Significance Index: -6.3700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4649
    Cell Significance Index: -15.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4651
    Cell Significance Index: -47.5100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4765
    Cell Significance Index: -54.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4946
    Cell Significance Index: -51.5000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5125
    Cell Significance Index: -10.2900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5306
    Cell Significance Index: -13.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5437
    Cell Significance Index: -14.8000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5508
    Cell Significance Index: -11.5300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5964
    Cell Significance Index: -12.9200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.6095
    Cell Significance Index: -36.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6148
    Cell Significance Index: -45.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6785
    Cell Significance Index: -52.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7266
    Cell Significance Index: -23.1400
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.7328
    Cell Significance Index: -7.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.7573
    Cell Significance Index: -10.8500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7616
    Cell Significance Index: -26.6800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.7774
    Cell Significance Index: -9.8100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7934
    Cell Significance Index: -53.3500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.8112
    Cell Significance Index: -8.4500
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.8257
    Cell Significance Index: -6.5700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.8415
    Cell Significance Index: -18.1800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.8585
    Cell Significance Index: -40.3500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.9140
    Cell Significance Index: -18.9600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.9595
    Cell Significance Index: -10.9000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.9746
    Cell Significance Index: -20.3400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.9874
    Cell Significance Index: -24.6300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0026
    Cell Significance Index: -52.6400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.0207
    Cell Significance Index: -11.1200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.0538
    Cell Significance Index: -7.1400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.0562
    Cell Significance Index: -15.5900
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -1.0819
    Cell Significance Index: -6.4200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -1.1903
    Cell Significance Index: -12.9400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.2118
    Cell Significance Index: -20.8900
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -1.2243
    Cell Significance Index: -11.1300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.2531
    Cell Significance Index: -32.9500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -1.2665
    Cell Significance Index: -20.8700
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -1.3140
    Cell Significance Index: -17.0400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.3299
    Cell Significance Index: -37.9500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.3434
    Cell Significance Index: -38.5100
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -1.3622
    Cell Significance Index: -26.8100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.3642
    Cell Significance Index: -50.0800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -1.3776
    Cell Significance Index: -27.4700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.3965
    Cell Significance Index: -16.7000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3977
    Cell Significance Index: -48.5700
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -1.3987
    Cell Significance Index: -15.4500
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -1.4100
    Cell Significance Index: -15.3900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cytoskeletal protein:** DCX is a member of the doublecortin family of cytoskeletal proteins, which are involved in the regulation of microtubule dynamics and neuronal migration. 2. **Neuronal migration and differentiation:** DCX is highly expressed in neurons undergoing migration and differentiation, particularly during the embryonic and postnatal periods. 3. **Axon guidance and projection:** DCX is also involved in the guidance and projection of axons, ensuring proper neural circuit formation and connectivity. 4. **Regulation of microtubule dynamics:** DCX interacts with microtubules and microtubule-associated proteins, influencing their stability and dynamics. **Pathways and Functions:** 1. **Axoneme assembly:** DCX interacts with other cytoskeletal proteins to regulate axoneme assembly and stability. 2. **Intracellular signal transduction:** DCX is involved in the regulation of intracellular signaling pathways, including those mediated by L1cam and neurofascin. 3. **Cytoskeleton organization:** DCX plays a crucial role in maintaining the organization and stability of the cytoskeleton, particularly in neurons. 4. **Neurodevelopmental processes:** DCX is essential for various neurodevelopmental processes, including neuronal migration, differentiation, and projection. **Clinical Significance:** Dysregulation of DCX has been implicated in various neurological disorders, including: 1. **Neurodegenerative diseases:** DCX has been associated with neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Cognitive impairments:** DCX has been linked to cognitive impairments, including attention-deficit/hyperactivity disorder (ADHD) and schizophrenia. 3. **Psychiatric conditions:** DCX has been implicated in psychiatric conditions, including autism spectrum disorder (ASD) and bipolar disorder. 4. **Neurodevelopmental disorders:** DCX has been associated with neurodevelopmental disorders, such as intellectual disability and epilepsy. In conclusion, DCX is a critical gene that plays a pivotal role in the development and function of the nervous system. Its dysregulation has significant implications for various neurological disorders, highlighting the importance of further research into the mechanisms underlying DCX-mediated processes.

Genular Protein ID: 3438490169

Symbol: DCX_HUMAN

Name: Neuronal migration protein doublecortin

UniProtKB Accession Codes:

O43602 A6NFY6 A9Z1V8 D3DUY8 D3DUY9 D3DUZ0 O43911 Q5JYZ5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 20 EMDB 6 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 14 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9489699

Title: A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome.

PubMed ID: 9489699

DOI: 10.1016/s0092-8674(00)80898-3

PubMed ID: 9489700

Title: Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein.

PubMed ID: 9489700

DOI: 10.1016/s0092-8674(00)80899-5

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 22359282

Title: Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology.

PubMed ID: 22359282

DOI: 10.1002/cm.21021

PubMed ID: 24607389

Title: Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growth.

PubMed ID: 24607389

DOI: 10.1016/j.ajhg.2014.02.004

PubMed ID: 12692530

Title: The DCX-domain tandems of doublecortin and doublecortin-like kinase.

PubMed ID: 12692530

DOI: 10.1038/nsb918

PubMed ID: 9668176

Title: Human doublecortin (DCX) and the homologous gene in mouse encode a putative Ca2+-dependent signaling protein which is mutated in human X-linked neuronal migration defects.

PubMed ID: 9668176

DOI: 10.1093/hmg/7.8.1327

PubMed ID: 9817918

Title: LIS1 and XLIS (DCX) mutations cause most classical lissencephaly, but different patterns of malformation.

PubMed ID: 9817918

DOI: 10.1093/hmg/7.13.2029

PubMed ID: 9618162

Title: Doublecortin is the major gene causing X-linked subcortical laminar heterotopia (SCLH).

PubMed ID: 9618162

DOI: 10.1093/hmg/7.7.1063

PubMed ID: 9989615

Title: Characterization of mutations in the gene doublecortin in patients with double cortex syndrome.

PubMed ID: 9989615

DOI: 10.1002/1531-8249(199902)45:2<146::aid-ana3>3.0.co;2-n

PubMed ID: 10369164

Title: A novel mutation of the doublecortin gene in Japanese patients with X-linked lissencephaly and subcortical band heterotopia.

PubMed ID: 10369164

DOI: 10.1007/s004390050963

PubMed ID: 10441340

Title: Subcortical band heterotopia in rare affected males can be caused by missense mutations in DCX (XLIS) or LIS1.

PubMed ID: 10441340

DOI: 10.1093/hmg/8.9.1757

PubMed ID: 10807542

Title: Genetic alteration of the DCX gene in Japanese patients with subcortical laminar heterotopia or isolated lissencephaly sequence.

PubMed ID: 10807542

DOI: 10.1007/s100380050204

PubMed ID: 11601509

Title: Mutation of the doublecortin gene in male patients with double cortex syndrome: somatic mosaicism detected by hair root analysis.

PubMed ID: 11601509

DOI: 10.1002/ana.1231

PubMed ID: 11175293

Title: Mutation analysis of the DCX gene and genotype/phenotype correlation in subcortical band heterotopia.

PubMed ID: 11175293

DOI: 10.1038/sj.ejhg.5200548

PubMed ID: 11468322

Title: Incomplete penetrance with normal MRI in a woman with germline mutation of the DCX gene.

PubMed ID: 11468322

DOI: 10.1212/wnl.57.2.327

PubMed ID: 12390976

Title: Subcortical band heterotopia (SBH) in males: clinical, imaging and genetic findings in comparison with females.

PubMed ID: 12390976

DOI: 10.1093/brain/awf248

PubMed ID: 12027577

Title: So-called 'cryptogenic' partial seizures resulting from a subtle cortical dysgenesis due to a doublecortin gene mutation.

PubMed ID: 12027577

DOI: 10.1053/seiz.2001.0607

PubMed ID: 12552055

Title: Somatic mosaicism and variable penetrance in doublecortin-associated migration disorders.

PubMed ID: 12552055

DOI: 10.1212/01.wnl.0000042091.90361.d2

PubMed ID: 27292316

Title: A novel DCX missense mutation in a family with X-linked lissencephaly and subcortical band heterotopia syndrome inherited from a low-level somatic mosaic mother: Genetic and functional studies.

PubMed ID: 27292316

DOI: 10.1016/j.ejpn.2016.05.010

Sequence Information:

  • Length: 365
  • Mass: 40574
  • Checksum: 1E859F2114CC3BB1
  • Sequence:
    • MELDFGHFDE RDKTSRNMRG SRMNGLPSPT HSAHCSFYRT RTLQALSNEK KAKKVRFYRN 
GDRYFKGIVY AVSSDRFRSF DALLADLTRS LSDNINLPQG VRYIYTIDGS RKIGSMDELE 
EGESYVCSSD NFFKKVEYTK NVNPNWSVNV KTSANMKAPQ SLASSNSAQA RENKDFVRPK 
LVTIIRSGVK PRKAVRVLLN KKTAHSFEQV LTDITEAIKL ETGVVKKLYT LDGKQVTCLH 
DFFGDDDVFI ACGPEKFRYA QDDFSLDENE CRVMKGNPSA TAGPKASPTP QKTSAKSPGP 
MRRSKSPADS GNDQDANGTS SSQLSTPKSK QSPISTPTSP GSLRKHKDLY LPLSLDDSDS 
LGDSM

Genular Protein ID: 1499922566

Symbol: A8K340_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K340

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 4 GO 13 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MANE-Select 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 1 SMART 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

Sequence Information:

  • Length: 366
  • Mass: 40673
  • Checksum: 8179C53CA5EE3448
  • Sequence:
    • MELDFGHFDE RDKTSRNMRG SRMNGLPSPT HSAHCSFYRT RTLQALSNEK KAKKVRFYRN 
GDRYFKGIVY AVSSDRFRSF DALLADLTRS LSDNINLPQG VRYIYTIDGS RKIGSMDELE 
EGESYVCSSD NFFKKVEYTK NVNPNWSVNV KTSANMKAPQ SLASSNSAQA RENKDFVRPK 
LVTIIRSGVK PRKAVRVLLN KKTAHSFEQV LTDITEAIKL ETGVVKKLYT LDGKQVTCLH 
DFFGDDDVFI ACGPEKFRYA QDDFSLDENE CRVMKGNPSA TAGPKASPTP QKTSAKSPGP 
MRRSKSPADS GNDQDANGTS SSQLSTPKSK QSPISTPTSP GSLRKHKVDL YLPLSLDDSD 
SLGDSM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.