Details for: DDX11

Gene ID: 1663

Symbol: DDX11

Ensembl ID: ENSG00000013573

Description: DEAD/H-box helicase 11

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.15
    Marker Score: 922
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71773
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47997
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30403
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2406
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 484
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 440
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2719.5
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4993
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5295
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 308
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.81
    Marker Score: 1158
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.81
    Marker Score: 232
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.79
    Marker Score: 537
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1266
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.78
    Marker Score: 2113
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.75
    Marker Score: 2227
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.74
    Marker Score: 11607
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.73
    Marker Score: 832
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.73
    Marker Score: 916
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 377
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.73
    Marker Score: 555
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.72
    Marker Score: 289
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.68
    Marker Score: 2859
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.68
    Marker Score: 905
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.67
    Marker Score: 615
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.67
    Marker Score: 499
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.66
    Marker Score: 270
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.66
    Marker Score: 169
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 0.65
    Marker Score: 616
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.6
    Marker Score: 1137.5
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.58
    Marker Score: 621
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.58
    Marker Score: 584
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.58
    Marker Score: 4298.5
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.56
    Marker Score: 406
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.55
    Marker Score: 136
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.55
    Marker Score: 145
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.55
    Marker Score: 930
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.55
    Marker Score: 603
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 432
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.52
    Marker Score: 856
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.52
    Marker Score: 311
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.51
    Marker Score: 1046
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.51
    Marker Score: 1872
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.49
    Marker Score: 1164
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.49
    Marker Score: 277
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.48
    Marker Score: 1317
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.48
    Marker Score: 237
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.48
    Marker Score: 994
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.47
    Marker Score: 2846
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.46
    Marker Score: 1643
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 0.46
    Marker Score: 111
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.44
    Marker Score: 292
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.44
    Marker Score: 569
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.43
    Marker Score: 898
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.42
    Marker Score: 409
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.41
    Marker Score: 633
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.41
    Marker Score: 170
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.4
    Marker Score: 1627
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.4
    Marker Score: 364
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 0.4
    Marker Score: 243
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.4
    Marker Score: 164
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.39
    Marker Score: 220
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.38
    Marker Score: 134
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.38
    Marker Score: 399
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.38
    Marker Score: 461
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.38
    Marker Score: 260
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.38
    Marker Score: 175
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.38
    Marker Score: 188
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.37
    Marker Score: 8370
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.37
    Marker Score: 103
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.37
    Marker Score: 195
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.37
    Marker Score: 111
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.37
    Marker Score: 382.5
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.37
    Marker Score: 4943
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.37
    Marker Score: 229.5
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.37
    Marker Score: 862
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.37
    Marker Score: 13473.5
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.36
    Marker Score: 183
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.36
    Marker Score: 199
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.36
    Marker Score: 104
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.36
    Marker Score: 224
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.36
    Marker Score: 503
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.35
    Marker Score: 176
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.35
    Marker Score: 3314
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.35
    Marker Score: 3309
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.35
    Marker Score: 231
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.35
    Marker Score: 4583
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.35
    Marker Score: 232
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.35
    Marker Score: 325
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.34
    Marker Score: 167.5
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.34
    Marker Score: 342
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.34
    Marker Score: 96
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.34
    Marker Score: 359
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.34
    Marker Score: 661
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.34
    Marker Score: 375
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.34
    Marker Score: 494
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.33
    Marker Score: 1293
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.33
    Marker Score: 237
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.33
    Marker Score: 107

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Other Information

**Key characteristics:** * DDX11 is a nuclear protein that is found in the nucleus of eukaryotic cells. * It is a helicase, which means that it can break DNA strands apart. * DDX11 is a member of the DEAD (double-strand exonuclease) family of DNA helicases. * It is a highly conserved protein that is found in organisms from yeast to humans. **Pathways and functions:** * DDX11 is involved in a variety of cellular processes, including DNA repair, replication, and transcription. * It is a key protein in the repair of DNA damage caused by ionizing radiation, chemicals, and viruses. * It is also involved in the replication of DNA in non-dividing cells. * DDX11 is a regulator of gene expression. It is involved in the regulation of the expression of genes involved in DNA repair, replication, and transcription. **Clinical significance:** * Mutations in the DDX11 gene have been linked to a number of human diseases, including cancer and neurodegenerative diseases. * These diseases are characterized by DNA damage and mutations, which can be caused by DDX11 mutations. * Therefore, DDX11 is a promising target for the treatment of cancer and neurodegenerative diseases.

Genular Protein ID: 970077289

Symbol: DDX11_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96FC9 Q13333 Q86VQ4 Q86W62 Q92498 Q92770 Q92998 Q92999

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CORUM 1 CPTC 1 CTD 1 ChEBI 11 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 EPD 1 Ensembl 5 ExpressionAtlas 1 GO 42 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 Rhea 1 SAM 1 SMART 2 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8798685

Title: The human homologue of the yeast CHL1 gene is a novel keratinocyte growth factor regulated gene.

PubMed ID: 8798685

DOI: 10.1074/jbc.271.40.24337

PubMed ID: 9013641

Title: Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1.

PubMed ID: 9013641

DOI: 10.1074/jbc.272.6.3823

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10648783

Title: Characterization of the enzymatic activity of hChlR1, a novel human DNA helicase.

PubMed ID: 10648783

DOI: 10.1093/nar/28.4.917

PubMed ID: 17105772

Title: The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells.

PubMed ID: 17105772

DOI: 10.1242/jcs.03262

PubMed ID: 17189189

Title: ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance.

PubMed ID: 17189189

DOI: 10.1016/j.molcel.2006.11.005

PubMed ID: 18499658

Title: Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1.

PubMed ID: 18499658

DOI: 10.1074/jbc.m802696200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20137776

Title: Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1.

PubMed ID: 20137776

DOI: 10.1016/j.ajhg.2010.01.008

PubMed ID: 20124417

Title: Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion.

PubMed ID: 20124417

DOI: 10.1242/jcs.057984

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21854770

Title: Mammalian ChlR1 has a role in heterochromatin organization.

PubMed ID: 21854770

DOI: 10.1016/j.yexcr.2011.08.006

PubMed ID: 22102414

Title: Biochemical characterization of Warsaw breakage syndrome helicase.

PubMed ID: 22102414

DOI: 10.1074/jbc.m111.276022

PubMed ID: 23116066

Title: The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas.

PubMed ID: 23116066

DOI: 10.1186/1476-4598-11-82

PubMed ID: 23797032

Title: Roles of ChlR1 DNA helicase in replication recovery from DNA damage.

PubMed ID: 23797032

DOI: 10.1016/j.yexcr.2013.06.005

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26089203

Title: The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development.

PubMed ID: 26089203

DOI: 10.1093/hmg/ddv213

PubMed ID: 27477908

Title: A Long Noncoding RNA Regulates Sister Chromatid Cohesion.

PubMed ID: 27477908

DOI: 10.1016/j.molcel.2016.06.031

PubMed ID: 26503245

Title: Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway.

PubMed ID: 26503245

DOI: 10.1093/nar/gkv1112

PubMed ID: 32705708

Title: Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.

PubMed ID: 32705708

DOI: 10.15252/embj.2019104185

PubMed ID: 23033317

Title: Identification and biochemical characterization of a novel mutation in DDX11 causing warsaw breakage syndrome.

PubMed ID: 23033317

DOI: 10.1002/humu.22226

Sequence Information:

  • Length: 970
  • Mass: 108313
  • Checksum: 5BF49FE74E912B48
  • Sequence:
    • MANETQKVGA IHFPFPFTPY SIQEDFMAEL YRVLEAGKIG IFESPTGTGK SLSLICGALS 
WLRDFEQKKR EEEARLLETG TGPLHDEKDE SLCLSSSCEG AAGTPRPAGE PAWVTQFVQK 
KEERDLVDRL KAEQARRKQR EERLQQLQHR VQLKYAAKRL RQEEEERENL LRLSREMLET 
GPEAERLEQL ESGEEELVLA EYESDEEKKV ASRVDEDEDD LEEEHITKIY YCSRTHSQLA 
QFVHEVKKSP FGKDVRLVSL GSRQNLCVNE DVKSLGSVQL INDRCVDMQR SRHEKKKGAE 
EEKPKRRRQE KQAACPFYNH EQMGLLRDEA LAEVKDMEQL LALGKEARAC PYYGSRLAIP 
AAQLVVLPYQ MLLHAATRQA AGIRLQDQVV IIDEAHNLID TITGMHSVEV SGSQLCQAHS 
QLLQYVERYG KRLKAKNLMY LKQILYLLEK FVAVLGGNIK QNPNTQSLSQ TGTELKTIND 
FLFQSQIDNI NLFKVQRYCE KSMISRKLFG FTERYGAVFS SREQPKLAGF QQFLQSLQPR 
TTEALAAPAD ESQASTLRPA SPLMHIQGFL AALTTANQDG RVILSRQGSL SQSTLKFLLL 
NPAVHFAQVV KECRAVVIAG GTMQPVSDFR QQLLACAGVE AERVVEFSCG HVIPPDNILP 
LVICSGISNQ PLEFTFQKRE LPQMMDEVGR ILCNLCGVVP GGVVCFFPSY EYLRQVHAHW 
EKGGLLGRLA ARKKIFQEPK SAHQVEQVLL AYSRCIQACG QERGQVTGAL LLSVVGGKMS 
EGINFSDNLG RCVVMVGMPF PNIRSAELQE KMAYLDQTLS PRPGTPREGS GGEPVHEGRQ 
PVHRQGHQAP EGFCQRSAPG PAICPAPCPG QAAGLDPSPC GGQSYLWPRH CCCAEVSPGE 
VGLFLMGNHT TAWRRALPLS CPLETVFVVG VVCGDPVTKV KPRRRVWSPE CCQDPGTGVS 
SRRRKWGNPE

Genular Protein ID: 3463577510

Symbol: Q2NKM7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2NKM7

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 3 SAM 2 SMART 2 SUPFAM 1 iPTMnet 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 906
  • Mass: 101622
  • Checksum: 2C4916339682C62B
  • Sequence:
    • MANETQKVGA IHFPFPFTPY SIQEDFMAEL YRVLEAGKIG IFESPTGTGK SLSLICGALS 
WLRDFEQKKR EEEARLLETG TGPLHDEKDE SLCLSSSCEG AAGTPRPAGE PAWVTQFVQK 
KEERDLVDRL KAEQARRKQR EERLQQLQHR VQLKYAAKRL RQEEEERENL LRLSREMLET 
GPEAERLEQL ESGEEELVLA EYESDEEKKV ASRVDEDEDD LEEEHITKIY YCSRTHSQLA 
QFVHEVKKSP FGKDVRLVSL GSRQNLCVNE DVKSLGSVQL INDRCVDMQR SRHEKKKGAE 
EEKPKRRRQE KQAACPFYNH EQMGLLRDEA LAEVKDMEQL LALGKEARAC PYYGSRLAIP 
AAQLVVLPYQ MLLHAATRQA AGIRLQDQVV IIDEAHNLID TITGMHSVEV SGSQLCQAHS 
QLLQYVERYG KRLKAKNLMY LKQILYLLEK FVAVLGGNIK QNPNTQSLSQ TGTELKTIND 
FLFQSQIDNI NLFKVQRYCE KSMISRKLFG FTERYGAVFS SREQPKLAGF QQFLQSLQPR 
TTEALAAPAD ESQASVPQPA SPLMHIEGFL AALTTANQDG RVILSRQGSL SQSTLKFLLL 
NPAVHFAQVV KECRAVVIAG GTMQPVSDFR QQLLACAGVE AERVVEFSCG HVIPPDNILP 
LVICIGVSNQ PLEFTFQKRD LPQMMDEVGR ILCNLCSVVS GGVVCFFPSY EYLRQVHAHW 
EKGGLLGHLA ARKKIFQEPK SAHQVEQVLL AYSRCIQACG QERGPVTGAL LLSVVGGKMS 
EGINFSDNLG RCVVMVGMPF PNIRSAELQE KMAYLDQTLP RAPGQAPPGK ALVENLCMKA 
VNQSIGRAIR HQKDFASIVL LDQRYARPPV LAKLPAWIRA RVEVKATFGP AIAAVQKFHR 
EKSASS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.