Details for: NQO1

Gene ID: 1728

Symbol: NQO1

Ensembl ID: ENSG00000181019

Description: NAD(P)H quinone dehydrogenase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 146.2597
    Cell Significance Index: -22.7500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 86.7360
    Cell Significance Index: -22.0000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 67.1930
    Cell Significance Index: -27.6800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 19.9059
    Cell Significance Index: -19.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.4759
    Cell Significance Index: -22.7800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.4775
    Cell Significance Index: -22.7100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.8388
    Cell Significance Index: -23.0400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 4.9005
    Cell Significance Index: 69.7600
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 2.7301
    Cell Significance Index: 23.4600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.4157
    Cell Significance Index: 52.3400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.7468
    Cell Significance Index: 104.8700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.6419
    Cell Significance Index: 15.1200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5665
    Cell Significance Index: 170.3900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4008
    Cell Significance Index: 278.0000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.2982
    Cell Significance Index: 96.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1412
    Cell Significance Index: 185.6100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.9522
    Cell Significance Index: 171.6600
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.9319
    Cell Significance Index: 5.7400
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.9245
    Cell Significance Index: 6.6400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8540
    Cell Significance Index: 24.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6322
    Cell Significance Index: 77.7400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.6030
    Cell Significance Index: 10.6600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5764
    Cell Significance Index: 314.7900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4955
    Cell Significance Index: 25.7400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.4811
    Cell Significance Index: 54.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4028
    Cell Significance Index: 10.0700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4003
    Cell Significance Index: 28.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3768
    Cell Significance Index: 10.5300
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.3511
    Cell Significance Index: 3.7300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.3424
    Cell Significance Index: 9.1800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3268
    Cell Significance Index: 6.9600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3122
    Cell Significance Index: 14.1500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2271
    Cell Significance Index: 2.5800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1711
    Cell Significance Index: 32.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1392
    Cell Significance Index: 61.5400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1298
    Cell Significance Index: 16.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0874
    Cell Significance Index: 8.6500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0607
    Cell Significance Index: 12.1800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0480
    Cell Significance Index: 30.4800
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.0426
    Cell Significance Index: 0.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0366
    Cell Significance Index: 67.5900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0334
    Cell Significance Index: 2.1100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0269
    Cell Significance Index: 0.7900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0234
    Cell Significance Index: 17.1300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0199
    Cell Significance Index: 0.1200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0111
    Cell Significance Index: 17.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0057
    Cell Significance Index: 10.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0019
    Cell Significance Index: 0.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0069
    Cell Significance Index: -4.3200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0084
    Cell Significance Index: -1.1500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0087
    Cell Significance Index: -6.4400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0091
    Cell Significance Index: -1.5500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0121
    Cell Significance Index: -9.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0129
    Cell Significance Index: -7.2900
  • Cell Name: colon endothelial cell (CL1001572)
    Fold Change: -0.0131
    Cell Significance Index: -0.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0148
    Cell Significance Index: -20.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0194
    Cell Significance Index: -13.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0281
    Cell Significance Index: -4.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0337
    Cell Significance Index: -15.3000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0462
    Cell Significance Index: -0.6300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0495
    Cell Significance Index: -14.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0499
    Cell Significance Index: -5.1000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0512
    Cell Significance Index: -1.6400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0533
    Cell Significance Index: -11.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0738
    Cell Significance Index: -1.9700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0759
    Cell Significance Index: -3.5400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0774
    Cell Significance Index: -1.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0820
    Cell Significance Index: -10.6000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0869
    Cell Significance Index: -2.3700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0902
    Cell Significance Index: -10.3300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1085
    Cell Significance Index: -12.6400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1367
    Cell Significance Index: -7.1200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1458
    Cell Significance Index: -7.3700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1761
    Cell Significance Index: -13.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1903
    Cell Significance Index: -22.4400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2120
    Cell Significance Index: -22.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2178
    Cell Significance Index: -10.2400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2428
    Cell Significance Index: -6.2400
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2489
    Cell Significance Index: -2.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2512
    Cell Significance Index: -19.2800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2554
    Cell Significance Index: -16.4800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2844
    Cell Significance Index: -12.5800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2940
    Cell Significance Index: -11.1300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3023
    Cell Significance Index: -20.3300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3029
    Cell Significance Index: -18.6200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3128
    Cell Significance Index: -4.8400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3484
    Cell Significance Index: -9.1600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3557
    Cell Significance Index: -4.2400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3773
    Cell Significance Index: -23.1300
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.3914
    Cell Significance Index: -5.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3999
    Cell Significance Index: -22.4400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4013
    Cell Significance Index: -21.0700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.4067
    Cell Significance Index: -6.8400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4298
    Cell Significance Index: -12.3200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4308
    Cell Significance Index: -4.4600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.4310
    Cell Significance Index: -3.6200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4354
    Cell Significance Index: -15.1300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4545
    Cell Significance Index: -9.7200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4930
    Cell Significance Index: -20.2000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5010
    Cell Significance Index: -7.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Antioxidant function**: NQO1 is a NAD(P)H-dependent enzyme that catalyzes the reduction of quinones, thereby protecting cells against oxidative stress and damage caused by ROS. 2. **Detoxification**: NQO1 is involved in the metabolism of various xenobiotics, including flavonoids, alkaloids, and certain amino acids, facilitating their detoxification and elimination from the body. 3. **Redox regulation**: NQO1 regulates the activity of other redox-sensitive enzymes, including NAD(P)H dehydrogenase and superoxide dismutase, thereby modulating the cellular redox status. 4. **Apoptosis regulation**: NQO1 has been shown to inhibit apoptosis in certain cell types, suggesting a role in promoting cell survival and preventing programmed cell death. 5. **Metabolic regulation**: NQO1 is involved in the metabolism of amino acids, polyamines, and vitamins, including vitamin E and vitamin K. **Pathways and Functions** NQO1 is involved in various cellular pathways, including: 1. **Keap1-Nrf2 pathway**: NQO1 is a key component of the Keap1-Nrf2 pathway, which regulates the expression of antioxidant and detoxification genes in response to oxidative stress. 2. **Cellular redox homeostasis**: NQO1 helps maintain cellular redox homeostasis by reducing ROS and regulating the activity of other redox-sensitive enzymes. 3. **Detoxification**: NQO1 is involved in the metabolism of various xenobiotics, facilitating their detoxification and elimination from the body. 4. **Apoptosis regulation**: NQO1 inhibits apoptosis in certain cell types, promoting cell survival and preventing programmed cell death. 5. **Metabolic regulation**: NQO1 is involved in the metabolism of amino acids, polyamines, and vitamins, including vitamin E and vitamin K. **Clinical Significance** Dysregulation of NQO1 has been implicated in various diseases, including: 1. **Cancer**: Reduced NQO1 expression has been observed in various types of cancer, suggesting a role in tumorigenesis and cancer progression. 2. **Neurodegenerative diseases**: NQO1 has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 3. **Metabolic disorders**: NQO1 is involved in the metabolism of amino acids and polyamines, and its dysregulation has been implicated in metabolic disorders, including diabetes and obesity. 4. **Toxicity**: NQO1 is involved in the metabolism of xenobiotics, and its dysregulation can lead to increased toxicity and sensitivity to certain chemicals. In conclusion, NQO1 is a critical gene involved in maintaining cellular redox homeostasis, antioxidant defenses, and detoxification processes. Its dysregulation has been implicated in various diseases, highlighting the importance of NQO1 in maintaining cellular health and preventing disease.

Genular Protein ID: 1265421833

Symbol: NQO1_HUMAN

Name: NAD(P)H dehydrogenase [quinone] 1

UniProtKB Accession Codes:

P15559 B2R5Y9 B4DNM7 B7ZAD1 Q86UK1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChEBI 28 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 20 DrugCentral 1 EC 2 EMBL 14 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 50 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 23 PDBsum 23 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 Rhea 8 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2843525

Title: Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.

PubMed ID: 2843525

DOI: 10.1016/s0021-9258(18)68280-8

PubMed ID: 1657151

Title: Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin.

PubMed ID: 1657151

DOI: 10.1021/bi00108a007

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8999809

Title: Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse.

PubMed ID: 8999809

DOI: 10.1074/jbc.272.3.1437

PubMed ID: 9271353

Title: The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant.

PubMed ID: 9271353

DOI: 10.1124/mol.52.2.300

PubMed ID: 15102952

Title: NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger.

PubMed ID: 15102952

DOI: 10.1124/mol.65.5.1238

PubMed ID: 15687255

Title: A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73.

PubMed ID: 15687255

DOI: 10.1101/gad.319905

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21636573

Title: Actin cytoskeleton remodeling by the alternatively spliced isoform of PDLIM4/RIL protein.

PubMed ID: 21636573

DOI: 10.1074/jbc.m111.241554

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28291250

Title: Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism.

PubMed ID: 28291250

DOI: 10.1038/srep44532

PubMed ID: 10543876

Title: Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954).

PubMed ID: 10543876

DOI: 10.1021/jm991060m

PubMed ID: 10706635

Title: Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release.

PubMed ID: 10706635

DOI: 10.1073/pnas.97.7.3177

PubMed ID: 11735396

Title: Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches.

PubMed ID: 11735396

DOI: 10.1021/bi011324i

PubMed ID: 11587640

Title: Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones.

PubMed ID: 11587640

DOI: 10.1016/s0969-2126(01)00636-0

PubMed ID: 16700548

Title: The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.

PubMed ID: 16700548

DOI: 10.1021/bi0600087

PubMed ID: 1737339

Title: NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.

PubMed ID: 1737339

PubMed ID: 10447260

Title: No linkage of P187S polymorphism in NAD(P)H: quinone oxidoreductase (NQO1/DIA4) and type 1 diabetes in the Danish population.

PubMed ID: 10447260

DOI: 10.1002/(sici)1098-1004(1999)14:1<67::aid-humu8>3.0.co;2-5

Sequence Information:

  • Length: 274
  • Mass: 30868
  • Checksum: A4010462AD00F3FE
  • Sequence:
    • MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL 
KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QFPLQWFGVP AILKGWFERV 
FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG IHGDMNVILW PIQSGILHFC 
GFQVLEPQLT YSIGHTPADA RIQILEGWKK RLENIWDETP LYFAPSSLFD LNFQAGFLMK 
KEVQDEEKNK KFGLSVGHHL GKSIPTDNQI KARK

Genular Protein ID: 3207259120

Symbol: B4DLR8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DLR8

Database IDs:

ARBA 17 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 21 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 3 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 8 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 202
  • Mass: 22793
  • Checksum: 845809C562CA8320
  • Sequence:
    • MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL 
KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QSGILHFCGF QVLEPQLTYS 
IGHTPADARI QILEGWKKRL ENIWDETPLY FAPSSLFDLN FQAGFLMKKE VQDEEKNKKF 
GLSVGHHLGK SIPTDNQIKA RK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.