Details for: SARDH

Gene ID: 1757

Symbol: SARDH

Ensembl ID: ENSG00000123453

Description: sarcosine dehydrogenase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 25.7160
    Cell Significance Index: -4.0000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 14.4691
    Cell Significance Index: -3.6700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 9.3783
    Cell Significance Index: -3.8100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.8349
    Cell Significance Index: 64.5000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 3.2280
    Cell Significance Index: -3.9800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.0111
    Cell Significance Index: -3.9900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 0.7912
    Cell Significance Index: -2.4300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.7329
    Cell Significance Index: 12.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6269
    Cell Significance Index: 124.4200
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.2699
    Cell Significance Index: 1.6700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2183
    Cell Significance Index: 4.5700
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.2164
    Cell Significance Index: 2.1700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.1468
    Cell Significance Index: 1.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1346
    Cell Significance Index: 17.2600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.1315
    Cell Significance Index: 2.1100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1183
    Cell Significance Index: 1.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0989
    Cell Significance Index: 19.8400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0833
    Cell Significance Index: 1.2300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0604
    Cell Significance Index: 1.7800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0599
    Cell Significance Index: 10.2300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0411
    Cell Significance Index: 0.9000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0347
    Cell Significance Index: 4.7600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0341
    Cell Significance Index: 0.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0333
    Cell Significance Index: 11.9400
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.0275
    Cell Significance Index: 0.1500
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.0144
    Cell Significance Index: 0.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0134
    Cell Significance Index: 25.2400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0119
    Cell Significance Index: 8.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0054
    Cell Significance Index: 8.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0049
    Cell Significance Index: 9.0100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0030
    Cell Significance Index: 0.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0028
    Cell Significance Index: 1.5500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0008
    Cell Significance Index: 0.5000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0005
    Cell Significance Index: -0.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0007
    Cell Significance Index: -0.1300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0011
    Cell Significance Index: -0.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0021
    Cell Significance Index: -0.9700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0028
    Cell Significance Index: -1.2400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0042
    Cell Significance Index: -3.1100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0045
    Cell Significance Index: -3.2900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0053
    Cell Significance Index: -4.0000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0058
    Cell Significance Index: -3.2900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0065
    Cell Significance Index: -0.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0069
    Cell Significance Index: -4.3100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0077
    Cell Significance Index: -0.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0080
    Cell Significance Index: -2.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0124
    Cell Significance Index: -1.4500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0198
    Cell Significance Index: -4.1600
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0224
    Cell Significance Index: -0.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0228
    Cell Significance Index: -2.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0238
    Cell Significance Index: -2.7300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0244
    Cell Significance Index: -1.5000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0278
    Cell Significance Index: -3.5900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0290
    Cell Significance Index: -2.9600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0290
    Cell Significance Index: -3.4200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0290
    Cell Significance Index: -0.8100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0314
    Cell Significance Index: -3.2700
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0321
    Cell Significance Index: -0.5100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0364
    Cell Significance Index: -1.8400
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: -0.0373
    Cell Significance Index: -0.2200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0425
    Cell Significance Index: -3.1700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0429
    Cell Significance Index: -3.2900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0436
    Cell Significance Index: -2.8100
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0445
    Cell Significance Index: -0.6300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0451
    Cell Significance Index: -3.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0491
    Cell Significance Index: -3.3000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0528
    Cell Significance Index: -1.0300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0539
    Cell Significance Index: -3.4000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0549
    Cell Significance Index: -2.8500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0575
    Cell Significance Index: -1.5400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0603
    Cell Significance Index: -1.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0630
    Cell Significance Index: -2.9600
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0641
    Cell Significance Index: -0.4900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0658
    Cell Significance Index: -3.4300
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.0661
    Cell Significance Index: -0.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0694
    Cell Significance Index: -3.0700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0696
    Cell Significance Index: -2.4200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0706
    Cell Significance Index: -0.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0718
    Cell Significance Index: -3.7700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0738
    Cell Significance Index: -2.3500
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0748
    Cell Significance Index: -1.2900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0763
    Cell Significance Index: -0.8300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0801
    Cell Significance Index: -2.0600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0818
    Cell Significance Index: -2.1500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0840
    Cell Significance Index: -2.7500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0858
    Cell Significance Index: -1.4700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0859
    Cell Significance Index: -3.0100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0866
    Cell Significance Index: -3.2800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0871
    Cell Significance Index: -2.1100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0885
    Cell Significance Index: -1.5300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0902
    Cell Significance Index: -2.2500
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -0.0988
    Cell Significance Index: -2.0600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0991
    Cell Significance Index: -1.9600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0994
    Cell Significance Index: -3.6500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1007
    Cell Significance Index: -3.5400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1018
    Cell Significance Index: -3.2200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1023
    Cell Significance Index: -2.5500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1042
    Cell Significance Index: -2.1200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1074
    Cell Significance Index: -2.2800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1080
    Cell Significance Index: -1.3400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzyme specificity:** SARDH is a mitochondrial enzyme that catalyzes the conversion of sarcosine to glycine and succinic semialdehyde. This reaction is a critical step in the sarcosine catabolic pathway, which is essential for energy production and the regulation of various cellular processes. 2. **Tissue distribution:** SARDH is highly expressed in various tissues, including the kidney, liver, retina, and brain, where it plays a crucial role in maintaining cellular homeostasis and regulating metabolic pathways. 3. **Cellular localization:** SARDH is primarily localized in the mitochondrial matrix, where it is involved in the regulation of energy metabolism and the synthesis of succinic semialdehyde, a key intermediate in the citric acid cycle. 4. **Regulatory mechanisms:** SARDH is subject to post-translational modifications, such as phosphorylation and ubiquitination, which regulate its activity and interaction with other enzymes and proteins. **Pathways and Functions:** 1. **Choline catabolism:** SARDH is involved in the degradation of sarcosine, a byproduct of choline metabolism. This pathway is crucial for the regulation of energy production and the synthesis of neurotransmitters, such as GABA. 2. **Metabolism of amino acids and derivatives:** SARDH is part of the broader metabolic network that regulates the catabolism of various amino acids and derivatives, including sarcosine, glycine, and succinic semialdehyde. 3. **Mitochondrial matrix:** SARDH is localized in the mitochondrial matrix, where it regulates energy metabolism, the synthesis of succinic semialdehyde, and the regulation of the citric acid cycle. 4. **Neurotransmission:** SARDH is expressed in the brain, where it is involved in the regulation of GABAergic neurotransmission and the synthesis of neurotransmitters. **Clinical Significance:** 1. **Neurological disorders:** Alterations in SARDH expression and activity have been linked to various neurological disorders, including epilepsy, schizophrenia, and autism spectrum disorder. 2. **Cancer:** SARDH has been identified as a potential biomarker for cancer diagnosis and prognosis, particularly in liver and kidney cancers. 3. **Metabolic disorders:** SARDH plays a crucial role in regulating energy metabolism and the catabolism of amino acids and derivatives. Alterations in SARDH expression and activity may contribute to the development of metabolic disorders, such as obesity and type 2 diabetes. 4. **Pharmacological applications:** SARDH inhibitors have been investigated as potential therapeutic agents for the treatment of various diseases, including cancer, neurological disorders, and metabolic disorders. In conclusion, SARDH is a critical enzyme involved in the catabolism of sarcosine and the regulation of energy metabolism, neurotransmission, and cellular homeostasis. Further research on SARDH and its role in various biological processes will provide valuable insights into the development of novel therapeutic strategies for various diseases.

Genular Protein ID: 969656208

Symbol: SARDH_HUMAN

Name: BPR-2

UniProtKB Accession Codes:

Q9UL12 B2RMR5 B4DPI2 B7ZLT6 Q5SYV0 Q9Y280 Q9Y2Y3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 31 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 Rhea 6 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10444331

Title: Cloning and mapping of the cDNA for human sarcosine dehydrogenase, a flavoenzyme defective in patients with sarcosinemia.

PubMed ID: 10444331

DOI: 10.1006/geno.1999.5886

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10686491

Title: Physical and cDNA mapping in the DBH region of human chromosome 9q34.

PubMed ID: 10686491

DOI: 10.1159/000022905

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 22825317

Title: Mutations in the sarcosine dehydrogenase gene in patients with sarcosinemia.

PubMed ID: 22825317

DOI: 10.1007/s00439-012-1207-x

Sequence Information:

  • Length: 918
  • Mass: 101037
  • Checksum: 4ADA132D5F44B37A
  • Sequence:
    • MASLSRALRV AAAHPRQSPT RGMGPCNLSS AAGPTAEKSV PYQRTLKEGQ GTSVVAQGPS 
RPLPSTANVV VIGGGSLGCQ TLYHLAKLGM SGAVLLERER LTSGTTWHTA GLLWQLRPSD 
VEVELLAHTR RVVSRELEEE TGLHTGWIQN GGLFIASNRQ RLDEYKRLMS LGKAYGVESH 
VLSPAETKTL YPLMNVDDLY GTLYVPHDGT MDPAGTCTTL ARAASARGAQ VIENCPVTGI 
RVWTDDFGVR RVAGVETQHG SIQTPCVVNC AGVWASAVGR MAGVKVPLVA MHHAYVVTER 
IEGIQNMPNV RDHDASVYLR LQGDALSVGG YEANPIFWEE VSDKFAFGLF DLDWEVFTQH 
IEGAINRVPV LEKTGIKSTV CGPESFTPDH KPLMGEAPEL RGFFLGCGFN SAGMMLGGGC 
GQELAHWIIH GRPEKDMHGY DIRRFHHSLT DHPRWIRERS HESYAKNYSV VFPHDEPLAG 
RNMRRDPLHE ELLGQGCVFQ ERHGWERPGW FHPRGPAPVL EYDYYGAYGS RAHEDYAYRR 
LLADEYTFAF PPHHDTIKKE CLACRGAAAV FDMSYFGKFY LVGLDARKAA DWLFSADVSR 
PPGSTVYTCM LNHRGGTESD LTVSRLAPSH QASPLAPAFE GDGYYLAMGG AVAQHNWSHI 
TTVLQDQKSQ CQLIDSSEDL GMISIQGPAS RAILQEVLDA DLSNEAFPFS THKLLRAAGH 
LVRAMRLSFV GELGWELHIP KASCVPVYRA VMAAGAKHGL INAGYRAIDS LSIEKGYRHW 
HADLRPDDSP LEAGLAFTCK LKSPVPFLGR EALEQQRAAG LRRRLVCFTM EDKVPMFGLE 
AIWRNGQVVG HVRRADFGFA IDKTIAYGYI HDPSGGPVSL DFVKSGDYAL ERMGVTYGAQ 
AHLKSPFDPN NKRVKGIY

Genular Protein ID: 2469320583

Symbol: A8K596_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K596

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 4 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 8 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 4

Sequence Information:

  • Length: 918
  • Mass: 100972
  • Checksum: E04923BE95CDDFAA
  • Sequence:
    • MASLSRALRV AAAHPRQSPT RGMGPCNLSS AAGPTAEKSV PYQRTLKEGQ GTSVVAQGPS 
RPLPSTANVV VIGGGSLGCQ TLYHLAKLGM SGAVLLERER LTSGTTWHTA GLLWQLRPSD 
VEVELLAHTR RVVSRELEEE TGLHTGWIQN GGLFIASNRQ RLDEYKRLMS LGKAYGVESH 
VLSPAETKTL YPLMNVDDLY GTLYVPHDGT MDPAGTCTTL ARAASARGAQ VIENCPVTGI 
RVWTDDFGVR RVAGVETQHG SIQTPCVVNC AGVWASAVGR MAGVKVPLVA MHHAYVVTER 
IEGIQNMPNV RDHDASVYLR LQGDALSVGG YEANPIFWEE VSDKFAFGLF DLDWEVFTQH 
IEGAINRVPV LDKTGIKSTV CGPESFTPDH KPLMGEAPEL RGFFLGCGFN SAGMMLGGGC 
GQELAHWIIH GRPEKDMHGY DIRRFHHSLT DHPRWIRERS HESYAKNYSV VFPHDEPLAG 
RNMRRDPLHE ELLGQGCVFQ ERHGWERPGW FHPRGPAPVL EYDYYGAYGS RAHEDYAYRR 
LLADEYTFAF PPHHDTIKKE CLACRGAAAV FDMSYFGKFY LVGLDARKAA DWLFSADVSR 
PPGSTVYTCM LNHHGGTESD LTVSRLAPSH QASPLAPAFE GDGYYLAVGG AVAQHNWSHI 
TTVLQDQKSQ CQLIDSSEDL GMISIQGPAS RAILQEVLDA DLSNEAFPFS THKLLRAAGH 
LVRAMRLSFV GELGWELHIP KASCVPVYRA VMAAGAKHGL INAGYRAIDS LSIEKGYRHW 
HADLRPDDSP LEAGLAFTCK LKSPVPFLGR EALEQQRAAG LRRRLVCFTM EDKVPMFGLE 
AIWRNGQVVG HVRRADFGFA IDKTIAYGYI HDPSGGPVSL DFVKSGDYAL ERMGVTYGAQ 
AHLKSPFDPN NKRVKGIY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.