Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 3.25
Marker Score: 15,040 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.62
Marker Score: 52,130 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.55
Marker Score: 38,071 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.53
Marker Score: 1,061 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.48
Marker Score: 19,046 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.44
Marker Score: 92,813 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.41
Marker Score: 765 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.4
Marker Score: 9,944 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.38
Marker Score: 3,993 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.35
Marker Score: 86,732 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.34
Marker Score: 4,763 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.18
Marker Score: 6,227 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.17
Marker Score: 8,373 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.14
Marker Score: 20,089 - Cell Name: mesangial cell (CL0000650)
Fold Change: 2.09
Marker Score: 2,522 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.06
Marker Score: 126,646 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.05
Marker Score: 21,123 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.98
Marker Score: 2,388 - Cell Name: neuron (CL0000540)
Fold Change: 1.93
Marker Score: 7,879 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.91
Marker Score: 523 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.91
Marker Score: 18,182 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.86
Marker Score: 16,004 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 1.86
Marker Score: 1,823 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.81
Marker Score: 1,710 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.64
Marker Score: 2,539 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.63
Marker Score: 3,753 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,919 - Cell Name: granule cell (CL0000120)
Fold Change: 1.44
Marker Score: 10,833 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.43
Marker Score: 519 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.42
Marker Score: 5,932 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.35
Marker Score: 403 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.26
Marker Score: 6,772 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.25
Marker Score: 823 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.23
Marker Score: 1,414 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.21
Marker Score: 2,839 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.16
Marker Score: 24,822 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.14
Marker Score: 598 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.14
Marker Score: 440 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.13
Marker Score: 2,288 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.09
Marker Score: 821 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.05
Marker Score: 5,509 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.04
Marker Score: 832 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.01
Marker Score: 567 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1
Marker Score: 480 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,805 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,030 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.98
Marker Score: 3,273 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 503 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.97
Marker Score: 570 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 457 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.92
Marker Score: 296 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,735 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5,183 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 322 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.89
Marker Score: 3,163 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 0.89
Marker Score: 1,248 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.88
Marker Score: 509 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,296 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.87
Marker Score: 5,201 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.87
Marker Score: 431 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.86
Marker Score: 13,452 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.85
Marker Score: 1,381 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.85
Marker Score: 2,418 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.83
Marker Score: 900 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.83
Marker Score: 493 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.81
Marker Score: 622 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.81
Marker Score: 1,775 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.81
Marker Score: 292 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.79
Marker Score: 247 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.79
Marker Score: 3,308 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.79
Marker Score: 972 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.78
Marker Score: 871 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.77
Marker Score: 309 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 392 - Cell Name: brush cell (CL0002204)
Fold Change: 0.75
Marker Score: 682 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 0.73
Marker Score: 190 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.73
Marker Score: 883 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.73
Marker Score: 294 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 0.72
Marker Score: 1,115 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.72
Marker Score: 313 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.72
Marker Score: 430 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.7
Marker Score: 871 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 176 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.68
Marker Score: 230 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.68
Marker Score: 196 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.68
Marker Score: 6,869 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.67
Marker Score: 155 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.67
Marker Score: 2,816 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.66
Marker Score: 22,393 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.66
Marker Score: 163 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.66
Marker Score: 340 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.64
Marker Score: 373 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.63
Marker Score: 548 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.6
Marker Score: 136 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.6
Marker Score: 1,163 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.6
Marker Score: 659 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.59
Marker Score: 568 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.58
Marker Score: 288
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1625338642
Symbol: DYN1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8101525
Title: Mutations in human dynamin block an intermediate stage in coated vesicle formation.
PubMed ID: 8101525
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7877694
Title: Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding.
PubMed ID: 7877694
DOI: 10.1038/374190a0
PubMed ID: 8910402
Title: Regulation of dynamin I GTPase activity by G protein betagamma subunits and phosphatidylinositol 4,5-bisphosphate.
PubMed ID: 8910402
PubMed ID: 9362482
Title: Domain structure and intramolecular regulation of dynamin GTPase.
PubMed ID: 9362482
PubMed ID: 9922133
Title: Dual function C-terminal domain of dynamin-1: modulation of self-assembly by interaction of the assembly site with SH3 domains.
PubMed ID: 9922133
DOI: 10.1021/bi981180g
PubMed ID: 9765310
Title: The pleckstrin homology domains of dynamin isoforms require oligomerization for high affinity phosphoinositide binding.
PubMed ID: 9765310
PubMed ID: 10074457
Title: Dominant-negative inhibition of receptor-mediated endocytosis by a dynamin-1 mutant with a defective pleckstrin homology domain.
PubMed ID: 10074457
PubMed ID: 12198492
Title: Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits.
PubMed ID: 12198492
DOI: 10.1038/ncb837
PubMed ID: 15703209
Title: SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.
PubMed ID: 15703209
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17257598
Title: Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis.
PubMed ID: 17257598
PubMed ID: 19084269
Title: GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission.
PubMed ID: 19084269
PubMed ID: 18353773
Title: A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
PubMed ID: 18353773
PubMed ID: 18088087
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23325789
Title: cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells.
PubMed ID: 23325789
PubMed ID: 29668686
Title: A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells.
PubMed ID: 29668686
PubMed ID: 25262651
Title: De novo mutations in synaptic transmission genes including DNM1 cause epileptic encephalopathies.
PubMed ID: 25262651
PubMed ID: 25533962
Title: Large-scale discovery of novel genetic causes of developmental disorders.
PubMed ID: 25533962
DOI: 10.1038/nature14135
PubMed ID: 7850421
Title: Three-dimensional solution structure of the pleckstrin homology domain from dynamin.
PubMed ID: 7850421
PubMed ID: 7954789
Title: Crystal structure at 2.2-A resolution of the pleckstrin homology domain from human dynamin.
PubMed ID: 7954789
PubMed ID: 7634088
Title: Crystal structure of the pleckstrin homology domain from dynamin.
PubMed ID: 7634088
DOI: 10.1038/nsb1194-782
PubMed ID: 20428113
Title: G domain dimerization controls dynamin's assembly-stimulated GTPase activity.
PubMed ID: 20428113
DOI: 10.1038/nature09032
PubMed ID: 26612256
Title: Crystal structure of the GTPase domain and the bundle signalling element of dynamin in the GDP state.
PubMed ID: 26612256
PubMed ID: 30069048
Title: Cryo-EM of the dynamin polymer assembled on lipid membrane.
PubMed ID: 30069048
PubMed ID: 27476654
Title: De novo mutations in SLC1A2 and CACNA1A are important causes of epileptic encephalopathies.
PubMed ID: 27476654
PubMed ID: 36553519
Title: Clinical, Radiological, and Genetic Characterization of a Patient with a Novel Homoallelic Loss-of-Function Variant in DNM1.
PubMed ID: 36553519
PubMed ID: 34172529
Title: Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state.
PubMed ID: 34172529
Sequence Information:
- Length: 864
- Mass: 97408
- Checksum: 7FCD8CB572FFEAEF
- Sequence:
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG SGIVTRRPLV LQLVNATTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD LANSDALKVA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL QSQLLSIEKE VEEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP PGVPSRSGQA SPSRPESPRP PFDL
Genular Protein ID: 3920745040
Symbol: B7ZAC0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 851
- Mass: 95823
- Checksum: 430C59CBEC697BAA
- Sequence:
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG SGIVTRRPLV LQLVNATTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD LANSDALKVA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL QSQLLSIEKE VEEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDLAFE ATVKKQVQKL KEPSIKCVDM VVSELTATIR KCSEKLQQYP RLREEMERIV TTHIREREGR TKGQVMLLID IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP PGVPRITISD P
Genular Protein ID: 183585983
Symbol: B4DK06_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 851
- Mass: 95828
- Checksum: 7BEDB48D8F649E69
- Sequence:
MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG SGIVTRRLLV LQLVNATTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD LANSDALKVA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL QSQLLSIEKE VEEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDLAFE ATVKKQVQKL KEPSIKCVDM VVSELTATIR KCSEKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SCLQVQSVPA GRRSPTSSPT PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP PGVPRITISD P
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.