Details for: ARID3A

Gene ID: 1820

Symbol: ARID3A

Ensembl ID: ENSG00000116017

Description: AT-rich interaction domain 3A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 113.7290
    Cell Significance Index: -17.6900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 62.9821
    Cell Significance Index: -15.9800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 40.6639
    Cell Significance Index: -16.5200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 40.1273
    Cell Significance Index: -18.9500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 36.0041
    Cell Significance Index: -18.5200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 14.3557
    Cell Significance Index: -17.7000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 9.7302
    Cell Significance Index: 259.8100
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 9.0207
    Cell Significance Index: 56.0500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.6596
    Cell Significance Index: -17.8400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.0953
    Cell Significance Index: -13.3400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.5172
    Cell Significance Index: -17.8300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.2400
    Cell Significance Index: 444.5400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.1692
    Cell Significance Index: 9.3400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0088
    Cell Significance Index: 910.8400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7932
    Cell Significance Index: 14.6600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.7469
    Cell Significance Index: 25.9600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.6698
    Cell Significance Index: 9.4000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6661
    Cell Significance Index: 65.8900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6410
    Cell Significance Index: 69.7200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6360
    Cell Significance Index: 121.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6360
    Cell Significance Index: 103.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6333
    Cell Significance Index: 35.5400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6083
    Cell Significance Index: 122.0300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5241
    Cell Significance Index: 31.4600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5135
    Cell Significance Index: 33.1300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.5054
    Cell Significance Index: 13.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3404
    Cell Significance Index: 23.5400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.3178
    Cell Significance Index: 1.9200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2926
    Cell Significance Index: 159.8000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2435
    Cell Significance Index: 12.7900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2420
    Cell Significance Index: 86.7900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1082
    Cell Significance Index: 8.3000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0944
    Cell Significance Index: 2.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0934
    Cell Significance Index: 127.0500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0901
    Cell Significance Index: 12.3800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0870
    Cell Significance Index: 2.3300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0838
    Cell Significance Index: 3.8000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0768
    Cell Significance Index: 144.6600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0648
    Cell Significance Index: 11.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0583
    Cell Significance Index: 2.0500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0578
    Cell Significance Index: 0.9900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0439
    Cell Significance Index: 19.4300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0410
    Cell Significance Index: 5.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0403
    Cell Significance Index: 62.0700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0345
    Cell Significance Index: 21.9000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0288
    Cell Significance Index: 53.1200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0257
    Cell Significance Index: 0.3500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0200
    Cell Significance Index: 3.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0117
    Cell Significance Index: 5.3100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0045
    Cell Significance Index: -0.0800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0070
    Cell Significance Index: -5.1700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0090
    Cell Significance Index: -6.6300
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.0092
    Cell Significance Index: -0.0400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0108
    Cell Significance Index: -8.1700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0114
    Cell Significance Index: -7.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0128
    Cell Significance Index: -1.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0143
    Cell Significance Index: -0.4000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0206
    Cell Significance Index: -2.9900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0210
    Cell Significance Index: -11.8400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0237
    Cell Significance Index: -0.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0420
    Cell Significance Index: -4.3000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0430
    Cell Significance Index: -9.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0460
    Cell Significance Index: -13.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0519
    Cell Significance Index: -6.7000
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0621
    Cell Significance Index: -0.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0647
    Cell Significance Index: -3.0400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0724
    Cell Significance Index: -4.4500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0728
    Cell Significance Index: -1.5500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0742
    Cell Significance Index: -5.5300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0788
    Cell Significance Index: -3.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0862
    Cell Significance Index: -9.8700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0895
    Cell Significance Index: -10.4300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0907
    Cell Significance Index: -10.7000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0995
    Cell Significance Index: -5.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1065
    Cell Significance Index: -7.1600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1216
    Cell Significance Index: -7.6700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1294
    Cell Significance Index: -13.4700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1300
    Cell Significance Index: -14.8500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1643
    Cell Significance Index: -3.5600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1742
    Cell Significance Index: -12.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1833
    Cell Significance Index: -8.1100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1875
    Cell Significance Index: -3.8900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1959
    Cell Significance Index: -4.1000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2040
    Cell Significance Index: -12.5100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2094
    Cell Significance Index: -10.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2122
    Cell Significance Index: -16.8100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2142
    Cell Significance Index: -6.1400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2152
    Cell Significance Index: -6.1400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2256
    Cell Significance Index: -6.6500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2344
    Cell Significance Index: -3.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2350
    Cell Significance Index: -8.9000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.3205
    Cell Significance Index: -3.9800
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.3230
    Cell Significance Index: -1.5500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3252
    Cell Significance Index: -8.1300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3373
    Cell Significance Index: -4.8300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3387
    Cell Significance Index: -9.2200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3419
    Cell Significance Index: -10.8900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3478
    Cell Significance Index: -11.1400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3567
    Cell Significance Index: -9.3800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3586
    Cell Significance Index: -11.7400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Domain structure:** The ARID3A protein contains an AT-rich interaction domain, which is essential for its function in chromatin remodeling and transcriptional regulation. 2. **Cellular localization:** ARID3A is predominantly found in the nucleus, where it interacts with other transcriptional regulators and chromatin remodeling complexes. 3. **Transcriptional regulation:** ARID3A acts as a transcriptional coregulator, enhancing the activity of RNA polymerase II and regulating the expression of target genes involved in cell cycle progression, apoptosis, and cellular stress responses. 4. **Interactions with other proteins:** ARID3A interacts with various proteins, including TP53, a tumor suppressor protein, and other transcriptional regulators, to modulate gene expression and transcriptional processes. **Pathways and Functions:** 1. **Chromatin remodeling:** ARID3A participates in chromatin remodeling complexes, facilitating the reorganization of chromatin structure and accessibility to transcriptional machinery. 2. **Transcriptional regulation by RNA polymerase II:** ARID3A enhances the activity of RNA polymerase II, a key enzyme in transcriptional initiation, and regulates the expression of target genes involved in cell cycle progression, apoptosis, and cellular stress responses. 3. **TP53-mediated transcriptional regulation:** ARID3A interacts with TP53, a tumor suppressor protein, to regulate the transcription of cell cycle genes and genes involved in G1 cell cycle arrest. 4. **Cellular stress responses:** ARID3A is involved in the regulation of transcriptional responses to cellular stress, including hypoxia and nutrient deprivation. **Clinical Significance:** 1. **Cancer:** Dysregulation of ARID3A has been implicated in various cancers, including breast cancer, lung cancer, and colorectal cancer, where it contributes to the development and progression of tumors. 2. **Cellular stress responses:** ARID3A plays a crucial role in regulating transcriptional responses to cellular stress, including hypoxia and nutrient deprivation, which are common in cancer and other diseases. 3. **Regulation of cell cycle progression:** ARID3A regulates the expression of cell cycle genes, including those involved in G1 cell cycle arrest, which is essential for maintaining genomic stability and preventing cancer. 4. **Therapeutic potential:** Targeting ARID3A and its interactions with other proteins may offer a novel therapeutic strategy for treating cancer and other diseases characterized by dysregulated transcriptional regulation and chromatin remodeling. In conclusion, the ARID3A gene plays a critical role in regulating gene expression and transcriptional processes, and its dysregulation has been implicated in various diseases, including cancer and cellular stress responses. Further research is necessary to fully understand the mechanisms of ARID3A and its role in human disease, with potential therapeutic implications for the treatment of cancer and other diseases.

Genular Protein ID: 466829677

Symbol: ARI3A_HUMAN

Name: AT-rich interactive domain-containing protein 3A

UniProtKB Accession Codes:

Q99856 Q5I858 Q6P9C6 Q8IZA7 Q8N4Z3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9722953

Title: The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome.

PubMed ID: 9722953

DOI: 10.1006/geno.1998.5259

PubMed ID: 9780002

Title: A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer.

PubMed ID: 9780002

DOI: 10.1038/sj.onc.1202163

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11812999

Title: A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

PubMed ID: 11812999

DOI: 10.1038/ncb742

PubMed ID: 12692263

Title: E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53.

PubMed ID: 12692263

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16738337

Title: Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I.

PubMed ID: 16738337

DOI: 10.1128/mcb.02009-05

PubMed ID: 17400556

Title: REKLES is an ARID3-restricted multifunctional domain.

PubMed ID: 17400556

DOI: 10.1074/jbc.m700397200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 20455271

Title: Solution NMR structure of the ARID domain of human AT-rich interactive domain-containing protein 3A: a human cancer protein interaction network target.

PubMed ID: 20455271

DOI: 10.1002/prot.22718

Sequence Information:

  • Length: 593
  • Mass: 62889
  • Checksum: 4D09131E168A2880
  • Sequence:
    • MKLQAVMETL LQRQQRARQE LEARQQLPPD PPAAPPGRAR AAPDEDREPE SARMQRAQMA 
ALAAMRAAAA GLGHPASPGG SEDGPPGSEE EDAAREGTPG SPGRGREGPG EEHFEDMASD 
EDMKPKWEEE EMEEDLGEDE EEEEEDYEDE EEEEDEEGLG PPGPASLGTT ALFPRKAQPP 
QAFRGDGVPR VLGGQERPGP GPAHPGGAAH VAPQLQPPDH GDWTYEEQFK QLYELDGDPK 
RKEFLDDLFS FMQKRGTPVN RIPIMAKQVL DLFMLYVLVT EKGGLVEVIN KKLWREITKG 
LNLPTSITSA AFTLRTQYMK YLYPYECEKR GLSNPNELQA AIDSNRREGR RQSFGGSLFA 
YSPGGAHGML SSPKLPVSSL GLAASTNGSS ITPAPKIKKE EDSAIPITVP GRLPVSLAGH 
PVVAAQAAAV QAAAAQAAVA AQAAALEQLR EKLESAEPPE KKMALVADEQ QRLMQRALQQ 
NFLAMAAQLP MSIRINSQAS ESRQDSAVNL TGTNGSNSIS MSVEINGIMY TGVLFAQPPA 
PTPTSAPNKG GGGGGGSSSN AGGRGGNTGT SGGQAGPAGL STPSTSTSNN SLP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.