Details for: EBF1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 238.9659
Cell Significance Index: -37.1700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 146.5838
Cell Significance Index: -37.1800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 30.1633
Cell Significance Index: -37.1900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 30.0011
Cell Significance Index: -65.6600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 18.1742
Cell Significance Index: 397.9500 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 14.8387
Cell Significance Index: 100.5400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 14.2226
Cell Significance Index: 277.5900 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 13.7077
Cell Significance Index: 172.6100 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 10.9947
Cell Significance Index: 114.5300 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 10.2247
Cell Significance Index: 44.5100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.3080
Cell Significance Index: -36.7300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 8.5219
Cell Significance Index: 146.0400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 7.9188
Cell Significance Index: 113.7200 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 6.3251
Cell Significance Index: 53.1300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 5.0058
Cell Significance Index: 107.0000 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.9056
Cell Significance Index: 41.7900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.6652
Cell Significance Index: 171.9500 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 2.0671
Cell Significance Index: 21.4100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.8695
Cell Significance Index: 70.8000 - Cell Name: perivascular cell (CL4033054)
Fold Change: 1.7673
Cell Significance Index: 8.1600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.0538
Cell Significance Index: 124.2700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.9951
Cell Significance Index: 127.5700 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.9206
Cell Significance Index: 11.4800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.7692
Cell Significance Index: 22.0500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.7489
Cell Significance Index: 102.8400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.5758
Cell Significance Index: 32.3100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.5693
Cell Significance Index: 10.0600 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.2963
Cell Significance Index: 1.7900 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: 0.2393
Cell Significance Index: 3.0200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1554
Cell Significance Index: 8.1600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1292
Cell Significance Index: 23.2900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0606
Cell Significance Index: 37.8200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0405
Cell Significance Index: 28.0200 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.0254
Cell Significance Index: 0.2100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0206
Cell Significance Index: 9.3400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0151
Cell Significance Index: -11.1800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0153
Cell Significance Index: -8.6500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0171
Cell Significance Index: -32.1400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0207
Cell Significance Index: -38.2200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0252
Cell Significance Index: -16.0300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0252
Cell Significance Index: -38.8700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0303
Cell Significance Index: -41.1700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.0349
Cell Significance Index: -0.5400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0367
Cell Significance Index: -2.8200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0509
Cell Significance Index: -38.5600 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0697
Cell Significance Index: -38.0600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0739
Cell Significance Index: -21.2500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0828
Cell Significance Index: -17.4500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0863
Cell Significance Index: -30.9700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0957
Cell Significance Index: -19.0000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1139
Cell Significance Index: -14.0000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1178
Cell Significance Index: -20.1100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1449
Cell Significance Index: -29.0600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1697
Cell Significance Index: -24.6700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2334
Cell Significance Index: -30.1500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2458
Cell Significance Index: -28.0600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.2565
Cell Significance Index: -5.3700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2794
Cell Significance Index: -28.5400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2913
Cell Significance Index: -33.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3396
Cell Significance Index: -25.3100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3424
Cell Significance Index: -39.2300 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.3429
Cell Significance Index: -5.4400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3547
Cell Significance Index: -36.9300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3849
Cell Significance Index: -18.0900 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: -0.3860
Cell Significance Index: -4.0600 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: -0.4000
Cell Significance Index: -4.6500 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: -0.4397
Cell Significance Index: -4.4000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.4869
Cell Significance Index: -25.3600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5320
Cell Significance Index: -35.7700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5322
Cell Significance Index: -32.6300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.5351
Cell Significance Index: -8.9600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.5551
Cell Significance Index: -34.1200 - Cell Name: mural cell (CL0008034)
Fold Change: -0.6095
Cell Significance Index: -7.4200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.6816
Cell Significance Index: -17.5200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.7236
Cell Significance Index: -37.5900 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.7520
Cell Significance Index: -7.2500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7817
Cell Significance Index: -49.2700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.7914
Cell Significance Index: -36.9000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.8159
Cell Significance Index: -11.6900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.8323
Cell Significance Index: -36.8200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.8379
Cell Significance Index: -29.1200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.9773
Cell Significance Index: -28.7900 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: -1.0137
Cell Significance Index: -9.3800 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -1.0161
Cell Significance Index: -20.6800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.0288
Cell Significance Index: -27.5200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.0363
Cell Significance Index: -38.0400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.0413
Cell Significance Index: -36.4800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.0709
Cell Significance Index: -31.4500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.0907
Cell Significance Index: -29.2300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.1002
Cell Significance Index: -36.0200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.1515
Cell Significance Index: -36.6800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -1.1601
Cell Significance Index: -28.1000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -1.1762
Cell Significance Index: -37.2000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -1.1874
Cell Significance Index: -29.6100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -1.1933
Cell Significance Index: -41.9300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -1.2056
Cell Significance Index: -32.1900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.2581
Cell Significance Index: -32.1400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.2727
Cell Significance Index: -36.3200 - Cell Name: adipocyte (CL0000136)
Fold Change: -1.2963
Cell Significance Index: -17.2800 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -1.3076
Cell Significance Index: -16.1800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2664861519
Symbol: COE1_HUMAN
Name: Transcription factor COE1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10942392
Title: Cloning of human early B-cell factor and identification of target genes suggest a conserved role in B-cell development in man and mouse.
PubMed ID: 10942392
PubMed ID: 14630787
Title: Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.
PubMed ID: 14630787
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 26819314
Title: Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor.
PubMed ID: 26819314
DOI: 10.1128/jvi.03227-15
PubMed ID: 27807034
Title: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.
PubMed ID: 27807034
PubMed ID: 28968461
Title: EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.
PubMed ID: 28968461
PubMed ID: 20592035
Title: Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif.
PubMed ID: 20592035
Sequence Information:
- Length: 591
- Mass: 64464
- Checksum: E47797B6FC1E5071
- Sequence:
MFGIQESIQR SGSSMKEEPL GSGMNAVRTW MQGAGVLDAN TAAQSGVGLA RAHFEKQPPS NLRKSNFFHF VLALYDRQGQ PVEIERTAFV GFVEKEKEAN SEKTNNGIHY RLQLLYSNGI RTEQDFYVRL IDSMTKQAIV YEGQDKNPEM CRVLLTHEIM CSRCCDKKSC GNRNETPSDP VIIDRFFLKF FLKCNQNCLK NAGNPRDMRR FQVVVSTTVN VDGHVLAVSD NMFVHNNSKH GRRARRLDPS EGTPSYLEHA TPCIKAISPS EGWTTGGATV IIIGDNFFDG LQVIFGTMLV WSELITPHAI RVQTPPRHIP GVVEVTLSYK SKQFCKGTPG RFIYTALNEP TIDYGFQRLQ KVIPRHPGDP ERLPKEVILK RAADLVEALY GMPHNNQEII LKRAADIAEA LYSVPRNHNQ LPALANTSVH AGMMGVNSFS GQLAVNVSEA SQATNQGFTR NSSSVSPHGY VPSTTPQQTN YNSVTTSMNG YGSAAMSNLG GSPTFLNGSA ANSPYAIVPS SPTMASSTSL PSNCSSSSGI FSFSPANMVS AVKQKSAFAP VVRPQTSPPP TCTSTNGNSL QAISGMIVPP M
Genular Protein ID: 554347143
Symbol: B4E2U8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 578
- Mass: 63026
- Checksum: F617F7E252D128C5
- Sequence:
MKEEPLGSGM NAVRTWMQGA GVLDANTAAQ SGVGLARAHF EKQPPSNLRK SNFFHFVLAL YDRQGQPVEI ERTAFVGFVE KEKEANSEKT NNGIHYRLQL LYSNGIRTEQ DFYVRLIDSM TKQAIVYEGQ DKNPEMCRVL LTHEIMCSRC CDKKSCGNRN ETPSDPVIID RFFLKFFLKC NQNCLKNAGN PRDMRRFQVV VSTTVNVDGH VLAVSDNMFV HNNSKHGRRA RRLDPSEGTP SYLEHAATPC IKAISPSEGW TTGGATVIII GDNFFDGLQV IFGTMLVWSE LITPHAIRVQ TPPRHIPGVV EVTLSYKSKQ FCKGTPGRFI YTALNEPTID YGFQRLQKVI PRHPGDPERL PKEVILKRAA DLVEALYGMP HNNQEIILKR AADIAEALYS VPRNHNQLPA LANTSVHAGM MGVNSFSGQL AVNVSEASQA TNQGFTRNSS SVSPHGYVPS TTPQQTNYNS VTTSMNGYGS AAMSNLGGSP TFLNGSAANS PYAIVPSSPT MASSTSLPSN CSSSSGIFSF SPANMVSAVK QKSAFAPVVR PQTSPPPTCT STNGNSLQAI SGMIVPPM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.