Details for: LPAR1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac neuron (CL0010022)
Fold Change: 5.17
Marker Score: 6,437 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 2.88
Marker Score: 747 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.48
Marker Score: 1,382 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.48
Marker Score: 4,774 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.44
Marker Score: 5,849 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 2.29
Marker Score: 1,504 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.15
Marker Score: 3,019 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.1
Marker Score: 1,044 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2
Marker Score: 986 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.62
Marker Score: 925 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.54
Marker Score: 2,923 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,573 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.38
Marker Score: 47,050 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.36
Marker Score: 1,566 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.23
Marker Score: 1,092 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.22
Marker Score: 280 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.21
Marker Score: 300 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 1.15
Marker Score: 286 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.14
Marker Score: 476 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 1.14
Marker Score: 286 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.12
Marker Score: 2,287 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.12
Marker Score: 779 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.07
Marker Score: 11,054 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 1.04
Marker Score: 234 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.03
Marker Score: 4,459 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 1.02
Marker Score: 6,122 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,791 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,016 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,406 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.97
Marker Score: 500 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.96
Marker Score: 3,728 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.96
Marker Score: 454 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,411 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 0.93
Marker Score: 400 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.93
Marker Score: 336 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 0.92
Marker Score: 2,414 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.92
Marker Score: 368 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,738 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.9
Marker Score: 10,112 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.89
Marker Score: 321 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.89
Marker Score: 17,678 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5,045 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.87
Marker Score: 229 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,273 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.83
Marker Score: 500 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.81
Marker Score: 260 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.8
Marker Score: 279 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.8
Marker Score: 611 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.79
Marker Score: 971 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.78
Marker Score: 10,257 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,261 - Cell Name: neural cell (CL0002319)
Fold Change: 0.77
Marker Score: 373 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.76
Marker Score: 337 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.76
Marker Score: 11,860 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.75
Marker Score: 390 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.74
Marker Score: 214 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.74
Marker Score: 3,100 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.73
Marker Score: 1,127 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.73
Marker Score: 382 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.72
Marker Score: 184 - Cell Name: brush cell (CL0002204)
Fold Change: 0.72
Marker Score: 657 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 177 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.68
Marker Score: 657 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.66
Marker Score: 134 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.66
Marker Score: 187 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.65
Marker Score: 713 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.64
Marker Score: 1,411 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 0.62
Marker Score: 532 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.62
Marker Score: 652 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.62
Marker Score: 724 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.6
Marker Score: 135 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.6
Marker Score: 193 - Cell Name: fat cell (CL0000136)
Fold Change: 0.6
Marker Score: 334 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.57
Marker Score: 237 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.56
Marker Score: 490 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.56
Marker Score: 2,334 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.56
Marker Score: 352 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: club cell (CL0000158)
Fold Change: 0.55
Marker Score: 647 - Cell Name: reticular cell (CL0000432)
Fold Change: 0.54
Marker Score: 198 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.54
Marker Score: 8,610 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.53
Marker Score: 2,043 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.52
Marker Score: 138 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.52
Marker Score: 343 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.52
Marker Score: 247 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 0.51
Marker Score: 706 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.5
Marker Score: 1,228 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.5
Marker Score: 564 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.49
Marker Score: 329 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 0.48
Marker Score: 238 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.47
Marker Score: 307 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.47
Marker Score: 1,097 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.46
Marker Score: 778 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.45
Marker Score: 143 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.45
Marker Score: 1,092 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.44
Marker Score: 2,882 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.44
Marker Score: 805 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.44
Marker Score: 475 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.44
Marker Score: 311 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.44
Marker Score: 9,300
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 453174699
Symbol: LPAR1_HUMAN
Name: Lysophosphatidic acid receptor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9070858
Title: Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
PubMed ID: 9070858
PubMed ID: 9069262
Title: Lysophosphatidic acid: G-protein signalling and cellular responses.
PubMed ID: 9069262
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11093753
PubMed ID: 18066075
Title: The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.
PubMed ID: 18066075
DOI: 10.1038/nm1685
PubMed ID: 19306925
Title: Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.
PubMed ID: 19306925
PubMed ID: 19656035
Title: Lysophosphatidic acid signals through specific lysophosphatidic acid receptor subtypes to control key regenerative responses of human gingival and periodontal ligament fibroblasts.
PubMed ID: 19656035
PubMed ID: 19733258
Title: Lysophosphatidic acid mediates migration of human mesenchymal stem cells stimulated by synovial fluid of patients with rheumatoid arthritis.
PubMed ID: 19733258
PubMed ID: 25025571
Title: Molecular regulation of lysophosphatidic acid receptor 1 trafficking to the cell surface.
PubMed ID: 25025571
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25732591
Title: Comparative analyses of lysophosphatidic acid receptor-mediated signaling.
PubMed ID: 25732591
PubMed ID: 31204173
Title: Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.
PubMed ID: 31204173
PubMed ID: 26091040
Title: Crystal structure of antagonist bound human lysophosphatidic acid receptor 1.
PubMed ID: 26091040
Sequence Information:
- Length: 364
- Mass: 41109
- Checksum: 4CA6262FD00DFE74
- Sequence:
MAAISTSIPV ISQPQFTAMN EPQCFYNESI AFFYNRSGKH LATEWNTVSK LVMGLGITVC IFIMLANLLV MVAIYVNRRF HFPIYYLMAN LAAADFFAGL AYFYLMFNTG PNTRRLTVST WLLRQGLIDT SLTASVANLL AIAIERHITV FRMQLHTRMS NRRVVVVIVV IWTMAIVMGA IPSVGWNCIC DIENCSNMAP LYSDSYLVFW AIFNLVTFVV MVVLYAHIFG YVRQRTMRMS RHSSGPRRNR DTMMSLLKTV VIVLGAFIIC WTPGLVLLLL DVCCPQCDVL AYEKFFLLLA EFNSAMNPII YSYRDKEMSA TFRQILCCQR SENPTGPTEG SDRSASSLNH TILAGVHSND HSVV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.