Details for: EPHA5

Gene ID: 2044

Symbol: EPHA5

Ensembl ID: ENSG00000145242

Description: EPH receptor A5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 10.9096
    Cell Significance Index: 612.1900
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 6.3657
    Cell Significance Index: 66.3100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 6.1348
    Cell Significance Index: 134.3300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 5.7557
    Cell Significance Index: 164.2500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 4.9384
    Cell Significance Index: 303.5400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 4.8635
    Cell Significance Index: 116.6400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.8381
    Cell Significance Index: -8.4000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.9026
    Cell Significance Index: 1041.1200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.8708
    Cell Significance Index: 193.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5394
    Cell Significance Index: 509.4000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.0460
    Cell Significance Index: 1415.1000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.2961
    Cell Significance Index: 27.7100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.5228
    Cell Significance Index: 6.7800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3964
    Cell Significance Index: 746.4000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3216
    Cell Significance Index: 12.1800
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.3155
    Cell Significance Index: 2.4200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.2654
    Cell Significance Index: 38.5800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.2599
    Cell Significance Index: 8.5100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.2009
    Cell Significance Index: 6.4000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1857
    Cell Significance Index: 285.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1693
    Cell Significance Index: 312.2500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.1580
    Cell Significance Index: 1.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1142
    Cell Significance Index: 72.5200
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.0845
    Cell Significance Index: 0.7000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0731
    Cell Significance Index: 1.8800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0687
    Cell Significance Index: 93.4600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0389
    Cell Significance Index: -0.3700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0459
    Cell Significance Index: -0.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0494
    Cell Significance Index: -36.6200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0531
    Cell Significance Index: -24.0800
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0570
    Cell Significance Index: -0.7600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0572
    Cell Significance Index: -41.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0623
    Cell Significance Index: -47.1900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0644
    Cell Significance Index: -2.8500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0750
    Cell Significance Index: -42.3200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0787
    Cell Significance Index: -49.1600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0966
    Cell Significance Index: -1.9400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1196
    Cell Significance Index: -1.5100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1212
    Cell Significance Index: -24.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1255
    Cell Significance Index: -36.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1276
    Cell Significance Index: -16.3600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1968
    Cell Significance Index: -41.4600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1975
    Cell Significance Index: -5.5200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2135
    Cell Significance Index: -38.4800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2174
    Cell Significance Index: -37.1300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2418
    Cell Significance Index: -33.2100
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.3086
    Cell Significance Index: -3.6000
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.3092
    Cell Significance Index: -5.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3271
    Cell Significance Index: -40.2200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.3365
    Cell Significance Index: -3.1900
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -0.3424
    Cell Significance Index: -3.5200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3487
    Cell Significance Index: -16.2600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.3490
    Cell Significance Index: -3.8500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3525
    Cell Significance Index: -6.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3545
    Cell Significance Index: -36.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3986
    Cell Significance Index: -46.4500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3994
    Cell Significance Index: -20.9700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4231
    Cell Significance Index: -48.4800
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.4278
    Cell Significance Index: -3.1100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4534
    Cell Significance Index: -11.3100
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.4683
    Cell Significance Index: -5.9100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4786
    Cell Significance Index: -10.3400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5277
    Cell Significance Index: -40.5000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5935
    Cell Significance Index: -8.5000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6086
    Cell Significance Index: -21.3200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.6320
    Cell Significance Index: -13.1900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6508
    Cell Significance Index: -41.0200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6512
    Cell Significance Index: -13.6300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6814
    Cell Significance Index: -35.5000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.6833
    Cell Significance Index: -4.6300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6837
    Cell Significance Index: -14.5100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7137
    Cell Significance Index: -12.2300
  • Cell Name: medial ganglionic eminence derived GABAergic cortical interneuron (CL4023069)
    Fold Change: -0.8073
    Cell Significance Index: -7.6300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.8107
    Cell Significance Index: -9.2100
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.8490
    Cell Significance Index: -8.4000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.9060
    Cell Significance Index: -42.5800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.9072
    Cell Significance Index: -18.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.9787
    Cell Significance Index: -26.6400
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.9807
    Cell Significance Index: -14.6700
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.9884
    Cell Significance Index: -6.4300
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.9988
    Cell Significance Index: -5.2300
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -1.0292
    Cell Significance Index: -13.4800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.0820
    Cell Significance Index: -39.7200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -1.1173
    Cell Significance Index: -21.9900
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -1.1284
    Cell Significance Index: -8.8500
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.1916
    Cell Significance Index: -14.2500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -1.2020
    Cell Significance Index: -15.7200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.2055
    Cell Significance Index: -42.3600
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -1.2064
    Cell Significance Index: -15.6100
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -1.2064
    Cell Significance Index: -17.1600
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.2153
    Cell Significance Index: -20.9500
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -1.2260
    Cell Significance Index: -16.3400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.2270
    Cell Significance Index: -18.1100
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -1.2608
    Cell Significance Index: -10.1800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -1.3050
    Cell Significance Index: -25.4700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.3263
    Cell Significance Index: -41.9500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -1.3528
    Cell Significance Index: -14.0000
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -1.3892
    Cell Significance Index: -16.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -1.3995
    Cell Significance Index: -37.3700
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -1.4425
    Cell Significance Index: -34.9400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** EPHA5 is a member of the Ephrin receptor family, which consists of 7 transmembrane receptors. These receptors are characterized by their unique structure, which includes an extracellular domain with an ephrin-binding site, a transmembrane domain, and an intracellular domain with tyrosine kinase activity. The EPHA5 receptor is specifically expressed in various cell types, including erythrocytes, Purkinje cells, and neurons. Its expression pattern suggests a role in axon guidance, neuronal development, and possibly immune cell function. **Pathways and Functions** EPHA5 is involved in several signaling pathways, including: 1. **Ephrin receptor activity**: EPHA5 binds to its ligand, ephrin-B2, and triggers a cascade of downstream signaling events that regulate cell migration, adhesion, and proliferation. 2. **Axon guidance**: EPHA5 is involved in the regulation of axon growth and guidance, which is crucial for neuronal development and connectivity. 3. **Neuronal development**: EPHA5 plays a role in the development and maturation of neurons, including the regulation of neuronal migration, differentiation, and synaptogenesis. 4. **Inflammation and immune response**: Although not its primary function, EPHA5 may also be involved in the regulation of immune responses, including the modulation of inflammatory processes and the activation of immune cells. **Clinical Significance** The EPHA5 gene has been studied in various disease models, including: 1. **Neurological disorders**: Mutations in the EPHA5 gene have been associated with neurological disorders, such as cerebral palsy and autism spectrum disorder. 2. **Cancer**: EPHA5 has been implicated in the development and progression of certain types of cancer, including breast and colon cancer. 3. **Inflammatory diseases**: EPHA5 may play a role in the regulation of inflammatory processes, which is relevant to the study of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, the EPHA5 gene encodes for a receptor that plays a critical role in the regulation of cellular processes, including axon guidance, neuronal development, and potentially immune cell function. Further studies are needed to elucidate the full extent of its clinical significance and to explore its potential as a therapeutic target for various diseases. **Recommendations for Future Research** 1. **Investigate the role of EPHA5 in the immune system**: Further studies are needed to elucidate the role of EPHA5 in the regulation of immune responses and to explore its potential as a therapeutic target for autoimmune diseases. 2. **Characterize the expression pattern of EPHA5**: A more detailed analysis of the expression pattern of EPHA5 in different cell types and tissues is needed to better understand its role in various physiological and pathological processes. 3. **Explore the therapeutic potential of EPHA5 inhibitors**: The development of EPHA5 inhibitors may provide a new avenue for the treatment of various diseases, including cancer and neurological disorders. By continuing to study the EPHA5 gene, we can gain a deeper understanding of its role in the regulation of cellular processes and its potential as a therapeutic target for various diseases.

Genular Protein ID: 3928961782

Symbol: EPHA5_HUMAN

Name: Ephrin type-A receptor 5

UniProtKB Accession Codes:

P54756 Q7Z3F2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 2 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 18 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIRSF 1 PRINTS 2 PRO 1 PROSITE 9 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 3 RefSeq 5 Rhea 3 SIGNOR 1 SMART 5 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9191074

Title: Extensive splice variation and localization of the EHK-1 receptor tyrosine kinase in adult human brain and glial tumors.

PubMed ID: 9191074

DOI: 10.1016/s0169-328x(96)00268-9

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 7898931

Title: cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

PubMed ID: 7898931

PubMed ID: 7748564

Title: Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation.

PubMed ID: 7748564

DOI: 10.1016/0896-6273(95)90335-6

PubMed ID: 9267020

Title: Unified nomenclature for Eph family receptors and their ligands, the ephrins.

PubMed ID: 9267020

DOI: 10.1016/s0092-8674(00)80500-0

PubMed ID: 10375373

Title: Immunohistochemical localization of EphA5 in the adult human central nervous system.

PubMed ID: 10375373

DOI: 10.1177/002215549904700702

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1037
  • Mass: 114803
  • Checksum: 578C2F4D950DE419
  • Sequence:
    • MRGSGPRGAG RRRPPSGGGD TPITPASLAG CYSAPRRAPL WTCLLLCAAL RTLLASPSNE 
VNLLDSRTVM GDLGWIAFPK NGWEEIGEVD ENYAPIHTYQ VCKVMEQNQN NWLLTSWISN 
EGASRIFIEL KFTLRDCNSL PGGLGTCKET FNMYYFESDD QNGRNIKENQ YIKIDTIAAD 
ESFTELDLGD RVMKLNTEVR DVGPLSKKGF YLAFQDVGAC IALVSVRVYY KKCPSVVRHL 
AVFPDTITGA DSSQLLEVSG SCVNHSVTDE PPKMHCSAEG EWLVPIGKCM CKAGYEEKNG 
TCQVCRPGFF KASPHIQSCG KCPPHSYTHE EASTSCVCEK DYFRRESDPP TMACTRPPSA 
PRNAISNVNE TSVFLEWIPP ADTGGRKDVS YYIACKKCNS HAGVCEECGG HVRYLPRQSG 
LKNTSVMMVD LLAHTNYTFE IEAVNGVSDL SPGARQYVSV NVTTNQAAPS PVTNVKKGKI 
AKNSISLSWQ EPDRPNGIIL EYEIKYFEKD QETSYTIIKS KETTITAEGL KPASVYVFQI 
RARTAAGYGV FSRRFEFETT PVFAASSDQS QIPVIAVSVT VGVILLAVVI GVLLSGSCCE 
CGCGRASSLC AVAHPSLIWR CGYSKAKQDP EEEKMHFHNG HIKLPGVRTY IDPHTYEDPN 
QAVHEFAKEI EASCITIERV IGAGEFGEVC SGRLKLPGKR ELPVAIKTLK VGYTEKQRRD 
FLGEASIMGQ FDHPNIIHLE GVVTKSKPVM IVTEYMENGS LDTFLKKNDG QFTVIQLVGM 
LRGISAGMKY LSDMGYVHRD LAARNILINS NLVCKVSDFG LSRVLEDDPE AAYTTRGGKI 
PIRWTAPEAI AFRKFTSASD VWSYGIVMWE VVSYGERPYW EMTNQDVIKA VEEGYRLPSP 
MDCPAALYQL MLDCWQKERN SRPKFDEIVN MLDKLIRNPS SLKTLVNASC RVSNLLAEHS 
PLGSGAYRSV GEWLEAIKMG RYTEIFMENG YSSMDAVAQV TLEDLRRLGV TLVGHQKKIM 
NSLQEMKVQL VNGMVPL

Genular Protein ID: 2335877857

Symbol: B7ZKW7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZKW7

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 7 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 Ensembl 2 GO 3 Gene3D 6 GeneTree 1 HGNC 1 InterPro 18 MANE-Select 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 13 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SAM 2 SMART 5 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1016
  • Mass: 112663
  • Checksum: 983E8C0B79387CD3
  • Sequence:
    • MRGSGPRGAG RRRPPSGGGD TPITPASLAG CYSAPRRAPL WTCLLLCAAL RTLLASPSNE 
VNLLDSRTVM GDLGWIAFPK NGWEEIGEVD ENYAPIHTYQ VCKVMEQNQN NWLLTSWISN 
EGASRIFIEL KFTLRDCNSL PGGLGTCKET FNMYYFESDD QNGRNIKENQ YIKIDTIAAD 
ESFTELDLGD RVMKLNTEVR DVGPLSKKGF YLAFQDVGAC IALVSVRVYY KKCPSVVRHL 
AVFPDTITGA DSSQLLEVSG SCVNHSVTDE PPKMHCSAEG EWLVPIGKCM CKAGYEEKNG 
TCQVCRPGFF KASPHIQSCG KCPPHSYTHE EASTSCVCEK DYFRRESDPP TMACTRPPSA 
PRNAISNVNE TSVFLEWIPP ADTGGRKDVS YYIACKKCNS HAGVCEECGG HVRYLPRQSG 
LKNTSVMMVD LLAHTNYTFE IEAVNGVSDL SPGARQYVSV NVTTNQAAPS PVTNVKKGKI 
AKNSISLSWQ EPDRPNGIIL EYEIKYFEKD QETSYTIIKS KETTITAEGL KPASVYVFQI 
RARTAAGYGV FSRRFEFETT PVSVAASSDQ SQIPVIAVSV TVGVILLAVV IGVLLSGRRC 
GYSKAKQDPE EEKMHFHNGH IKLPGVRTYI DPHTYEDPNQ AVHEFAKEIE ASCITIERVI 
GAGEFGEVCS GRLKLPGKRE LPVAIKTLKV GYTEKQRRDF LGEASIMGQF DHPNIIHLEG 
VVTKSKPVMI VTEYMENGSL DTFLKKNDGQ FTVIQLVGML RGISAGMKYL SDMGYVHRDL 
AARNILINSN LVCKVSDFGL SRVLEDDPEA AYTTRGGKIP IRWTAPEAIA FRKFTSASDV 
WSYGIVMWEV VSYGERPYWE MTNQDVIKAV EEGYRLPSPM DCPAALYQLM LDCWQKERNS 
RPKFDEIVNM LDKLIRNPSS LKTLVNASCR VSNLLAEHSP LGSGAYRSVG EWLEAIKMGR 
YTEIFMENGY SSMDAVAQVT LEDLRRLGVT LVGHQKKIMN SLQEMKVQLV NGMVPL

Genular Protein ID: 428884320

Symbol: Q59FT4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FT4

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 7 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 3 Gene3D 6 InterPro 19 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 12 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 5 RefSeq 3 Rhea 3 SAM 1 SMART 4 SUPFAM 5

Sequence Information:

  • Length: 1017
  • Mass: 112188
  • Checksum: 93223CA1C38E6F87
  • Sequence:
    • AARDSGTGGG SEKMRGSGPR GAGRRRPPSG GGDTPITPAS LAGCYSAPRR APLWTCLLLC 
AALRTLLASP SNEVNLLDSR TVMGDLGWIA FPKNGWEEIG EVDENYAPIH TYQVCKVMEQ 
NQNNWLLTSW ISNEGASRIF IELKFTLRDC NSLPGGLGTC KETFNMYYFE SDDQNGRNIK 
ENQYIKIDTI AADESFTELD LGDRVMKLNT EVRDVGPLSK KGFYLAFQDV GACIALVSVR 
VYYKKCPSVV RHLAVFPDTI TGADSSQLLE VSGSCVNHSV TDEPPKMHCS AEGEWLVPIG 
KCMCKAGYEE KNGTCQVCRP GFFKASPHIQ SCGKCPPHSY THEEASTSCV CEKDYFRRES 
DPPTMACTRP PSAPRNAISN VNETSVFLEW IPPADTGGRK DVSYYIACKK CNSHAGVCEE 
CGGHVRYLPR QSGLKNTSVM MVDLLAHTNY TFEIEAVNGV SDLSPGARQY VSVNVTTNQA 
APSPVTNVKK GKIAKNSISL SWQEPDRPNG IILEYEIKYF EKDQETSYTI IKSKETTITA 
EGLKPASVYV FQIRARTAAG YGVFSRRFEF ETTPVSVAAS SDQSQIPVIA VSVTVGVILL 
AVVIGVLLSG SCCECGCGRA SSLCAVAHPS LIWRCGYSKA KQDPEEEKMH FHNGHIKLPG 
VRTYIDPHTY EDPNQAVHEF AKEIEASCIT IERVIGAGEF GEVCSGRLKL PGKRELPVAI 
KTLKVGYTEK QRRDFLGEAS IMGQFDHPNI IHLEGVVTKS KPVMIVTEYM ENGSLDTFLK 
KNDGQFTVIQ LVGMLRGISA GMKYLSDMGY VHRDLAARNI LINSNLVCKV SDFGLSRVLE 
DDPEAAYTTR GGKIPIRWTA PEAIAFRKFT SASDVWSYGI VMWEVVSYGE RPYWEMTNQD 
VIKAVEEGYR LPSPMDCPAA LYQLMLDCWQ KERNSRPKFD EIVNMLDKLI RNPSSLKTLV 
NASCRVSNLL AEHSPLGSGA YRSVGEWLEA IKMGRYTEIF MENGYSSMDA VAQVTLE

Genular Protein ID: 3375672751

Symbol: F8W9W0_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8W9W0

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 5 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 17 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 13 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 3 SAM 1 SMART 4 SMR 1 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 874
  • Mass: 96882
  • Checksum: C4963B7597211ECC
  • Sequence:
    • MRGSGPRGAG RRRPPSGGGD TPITPASLAG CYSAPRRAPL WTCLLLCAAL RTLLASPSNE 
VNLLDSRTVM GDLGWIAFPK NGWEEIGEVD ENYAPIHTYQ VCKVMEQNQN NWLLTSWISN 
EGASRIFIEL KFTLRDCNSL PGGLGTCKET FNMYYFESDD QNGRNIKENQ YIKIDTIAAD 
ESFTELDLGD RVMKLNTEVR DVGPLSKKGF YLAFQDVGAC IALVSVRVYY KKCPSVVRHL 
AVFPDTITGA DSSQLLEVSG SCVNHSVTDE PPKMHCSAEG EWLVPIGKCM CKAGYEEKNG 
TCQAPSPVTN VKKGKIAKNS ISLSWQEPDR PNGIILEYEI KYFEKDQETS YTIIKSKETT 
ITAEGLKPAS VYVFQIRART AAGYGVFSRR FEFETTPVSV AASSDQSQIP VIAVSVTVGV 
ILLAVVIGVL LSGSCCECGC GRASSLCAVA HPSLIWRCGY SKAKQDPEEE KMHFHNGHIK 
LPGVRTYIDP HTYEDPNQAV HEFAKEIEAS CITIERVIGA GEFGEVCSGR LKLPGKRELP 
VAIKTLKVGY TEKQRRDFLG EASIMGQFDH PNIIHLEGVV TKSKPVMIVT EYMENGSLDT 
FLKKNDGQFT VIQLVGMLRG ISAGMKYLSD MGYVHRDLAA RNILINSNLV CKVSDFGLSR 
VLEDDPEAAY TTRGGKIPIR WTAPEAIAFR KFTSASDVWS YGIVMWEVVS YGERPYWEMT 
NQDVIKAVEE GYRLPSPMDC PAALYQLMLD CWQKERNSRP KFDEIVNMLD KLIRNPSSLK 
TLVNASCRVS NLLAEHSPLG SGAYRSVGEW LEAIKMGRYT EIFMENGYSS MDAVAQVTLE 
DLRRLGVTLV GHQKKIMNSL QEMKVQLVNG MVPL

Genular Protein ID: 2037988719

Symbol: F8VP57_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8VP57

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 7 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 6 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 19 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 13 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 3 SAM 1 SMART 4 SMR 1 SUPFAM 5 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1004
  • Mass: 111014
  • Checksum: DDF3AB992B67DAA5
  • Sequence:
    • MRGSGPRGAG RRRPPSGGGD TPITPASLAG CYSAPRRAPL WTCLLLCAAL RTLLASPSNE 
VNLLDSRTVM GDLGWIAFPK NGWEEIGEVD ENYAPIHTYQ VCKVMEQNQN NWLLTSWISN 
EGASRIFIEL KFTLRDCNSL PGGLGTCKET FNMYYFESDD QNGRNIKENQ YIKIDTIAAD 
ESFTELDLGD RVMKLNTEVR DVGPLSKKGF YLAFQDVGAC IALVSVRVYY KKCPSVVRHL 
AVFPDTITGA DSSQLLEVSG SCVNHSVTDE PPKMHCSAEG EWLVPIGKCM CKAGYEEKNG 
TCQVCRPGFF KASPHIQSCG KCPPHSYTHE EASTSCVCEK DYFRRESDPP TMACTRPPSA 
PRNAISNVNE TSVFLEWIPP ADTGGRKDVS YYIACKKCNS HAGVCEECGG HVRYLPRQSG 
LKNTSVMMVD LLAHTNYTFE IEAVNGVSDL SPGARQYVSV NVTTNQAAPS PVTNVKKGKI 
AKNSISLSWQ EPDRPNGIIL EYEIKYFEKD QETSYTIIKS KETTITAEGL KPASVYVFQI 
RARTAAGYGV FSRRFEFETT PVSVAASSDQ SQIPVIAVSV TVGVILLAVV IGVLLSGSCC 
ECGCGRASSL CAVAHPSLIW RCGYSKAKQD PEEEKMHFHN GHIKLPGVRT YIDPHTYEDP 
NQAVHEFAKE IEASCITIER VIGAGEFGEV CSGRLKLPGK RELPVAIKTL KVGYTEKQRR 
DFLGEASIMG QFDHPNIIHL EGVVTKSKPV MIVTEYMENG SLDTFLKKND GQFTVIQLVG 
MLRGISAGMK YLSDMGYVHR DLAARNILIN SNLVCKVSDF GLSRVLEDDP EAAYTTRGGK 
IPIRWTAPEA IAFRKFTSAS DVWSYGIVMW EVVSYGERPY WEMTNQDVIK AVEEGYRLPS 
PMDCPAALYQ LMLDCWQKER NSRPKFDEIV NMLDKLIRNP SSLKTLVNAS CRVSNLLAEH 
SPLGSGAYRS VGEWLEAIKM GRYTEIFMEN GYSSMDAVAQ VTLE

Genular Protein ID: 658836652

Symbol: B7ZKJ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZKJ3

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 7 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 10 Ensembl 2 GO 3 Gene3D 6 GeneTree 1 HGNC 1 InterPro 19 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 13 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 4 Rhea 3 SAM 1 SMART 5 SUPFAM 5 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1038
  • Mass: 114842
  • Checksum: 8BF8E00B05D28EDD
  • Sequence:
    • MRGSGPRGAG RRRPPSGGGD TPITPASLAG CYSAPRRAPL WTCLLLCAAL RTLLASPSNE 
VNLLDSRTVM GDLGWIAFPK NGWEEIGEVD ENYAPIHTYQ VCKVMEQNQN NWLLTSWISN 
EGASRIFIEL KFTLRDCNSL PGGLGTCKET FNMYYFESDD QNGRNIKENQ YIKIDTIAAD 
ESFTELDLGD RVMKLNTEVR DVGPLSKKGF YLAFQDVGAC IALVSVRVYY KKCPSVVRHL 
AVFPDTITGA DSSQLLEVSG SCVNHSVTDE PPKMHCSAEG EWLVPIGKCM CKAGYEEKNG 
TCQVCRPGFF KASPHIQSCG KCPPHSYTHE EASTSCVCEK DYFRRESDPP TMACTRPPSA 
PRNAISNVNE TSVFLEWIPP ADTGGRKDVS YYIACKKCNS HAGVCEECGG HVRYLPRQSG 
LKNTSVMMVD LLAHTNYTFE IEAVNGVSDL SPGARQYVSV NVTTNQAAPS PVTNVKKGKI 
AKNSISLSWQ EPDRPNGIIL EYEIKYFEKD QETSYTIIKS KETTITAEGL KPASVYVFQI 
RARTAAGYGV FSRRFEFETT PVSVAASSDQ SQIPVIAVSV TVGVILLAVV IGVLLSGSCC 
ECGCGRASSL CAVAHPSLIW RCGYSKAKQD PEEEKMHFHN GHIKLPGVRT YIDPHTYEDP 
NQAVHEFAKE IEASCITIER VIGAGEFGEV CSGRLKLPGK RELPVAIKTL KVGYTEKQRR 
DFLGEASIMG QFDHPNIIHL EGVVTKSKPV MIVTEYMENG SLDTFLKKND GQFTVIQLVG 
MLRGISAGMK YLSDMGYVHR DLAARNILIN SNLVCKVSDF GLSRVLEDDP EAAYTTRGGK 
IPIRWTAPEA IAFRKFTSAS DVWSYGIVMW EVVSYGERPY WEMTNQDVIK AVEEGYRLPS 
PMDCPAALYQ LMLDCWQKER NSRPKFDEIV NMLDKLIRNP SSLKTLVNAS CRVSNLLAEH 
SPLGSGAYRS VGEWLEAIKM GRYTEIFMEN GYSSMDAVAQ VTLEDLRRLG VTLVGHQKKI 
MNSLQEMKVQ LVNGMVPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.