Details for: FDXR

Gene ID: 2232

Symbol: FDXR

Ensembl ID: ENSG00000161513

Description: ferredoxin reductase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 64.6114
    Cell Significance Index: -10.0500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 38.6763
    Cell Significance Index: -9.8100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 23.0396
    Cell Significance Index: -9.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 10.0109
    Cell Significance Index: 268.2500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 9.8561
    Cell Significance Index: -9.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.8162
    Cell Significance Index: -10.8700
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 7.1620
    Cell Significance Index: 35.7300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 4.1042
    Cell Significance Index: 107.9200
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 3.9272
    Cell Significance Index: 19.1000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.3326
    Cell Significance Index: -8.9300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 3.0792
    Cell Significance Index: 585.9900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.3246
    Cell Significance Index: -7.1400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.7024
    Cell Significance Index: 168.4100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.7022
    Cell Significance Index: 28.0500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.6858
    Cell Significance Index: 21.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.4678
    Cell Significance Index: 76.2500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1783
    Cell Significance Index: 1063.8900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1000
    Cell Significance Index: 66.0400
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.0715
    Cell Significance Index: 15.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9289
    Cell Significance Index: 151.0800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8384
    Cell Significance Index: 38.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7415
    Cell Significance Index: 86.4100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5616
    Cell Significance Index: 38.8400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5445
    Cell Significance Index: 14.8200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.5386
    Cell Significance Index: 8.0700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.4878
    Cell Significance Index: 11.2700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4837
    Cell Significance Index: 13.9400
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.3643
    Cell Significance Index: 2.1400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3563
    Cell Significance Index: 7.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3537
    Cell Significance Index: 193.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3528
    Cell Significance Index: 70.0100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3463
    Cell Significance Index: 62.4300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3308
    Cell Significance Index: 40.6800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.2735
    Cell Significance Index: 3.9200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2610
    Cell Significance Index: 18.4600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2421
    Cell Significance Index: 107.0500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2221
    Cell Significance Index: 2.0500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1925
    Cell Significance Index: 5.3800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1863
    Cell Significance Index: 5.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1862
    Cell Significance Index: 25.5700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1711
    Cell Significance Index: 118.3600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1087
    Cell Significance Index: 5.0700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1024
    Cell Significance Index: 6.6100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0890
    Cell Significance Index: 2.8500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0798
    Cell Significance Index: 1.2800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0781
    Cell Significance Index: 2.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0696
    Cell Significance Index: 1.7400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0554
    Cell Significance Index: 1.1800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0493
    Cell Significance Index: 6.3700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0491
    Cell Significance Index: 2.5600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0438
    Cell Significance Index: 8.7900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0417
    Cell Significance Index: 1.4700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0285
    Cell Significance Index: 0.7600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0282
    Cell Significance Index: 3.6200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0273
    Cell Significance Index: 9.7800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0269
    Cell Significance Index: 0.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0195
    Cell Significance Index: 1.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0180
    Cell Significance Index: 2.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.8200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0036
    Cell Significance Index: -6.7100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0055
    Cell Significance Index: -8.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0057
    Cell Significance Index: -4.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0066
    Cell Significance Index: -1.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0067
    Cell Significance Index: -5.0600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0091
    Cell Significance Index: -12.3900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0116
    Cell Significance Index: -1.1800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0145
    Cell Significance Index: -9.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0152
    Cell Significance Index: -11.2700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0185
    Cell Significance Index: -10.4100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0216
    Cell Significance Index: -13.4800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0218
    Cell Significance Index: -9.9000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0249
    Cell Significance Index: -0.3600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0294
    Cell Significance Index: -8.4600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0594
    Cell Significance Index: -0.8100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0595
    Cell Significance Index: -3.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0598
    Cell Significance Index: -12.5900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.0614
    Cell Significance Index: -0.4900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0625
    Cell Significance Index: -0.7100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0658
    Cell Significance Index: -9.5600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0721
    Cell Significance Index: -8.2600
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.0722
    Cell Significance Index: -0.6200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0808
    Cell Significance Index: -4.2400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0817
    Cell Significance Index: -3.8400
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.0843
    Cell Significance Index: -0.1900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1040
    Cell Significance Index: -10.8300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1122
    Cell Significance Index: -8.8900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1153
    Cell Significance Index: -7.0700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1165
    Cell Significance Index: -8.9400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1186
    Cell Significance Index: -3.0300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1257
    Cell Significance Index: -1.8000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1527
    Cell Significance Index: -10.2700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1559
    Cell Significance Index: -2.3500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1594
    Cell Significance Index: -1.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1616
    Cell Significance Index: -2.7700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1676
    Cell Significance Index: -2.8100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1799
    Cell Significance Index: -5.3000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1869
    Cell Significance Index: -10.4900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1916
    Cell Significance Index: -4.0100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1937
    Cell Significance Index: -9.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FDXR is a flavoprotein enzyme that catalyzes the reduction of ferredoxin, a small protein containing iron-sulfur clusters. This reaction is essential for the electron transport chain, which generates energy for cellular processes. FDXR is a member of the cytochrome P450 superfamily, which plays a critical role in the metabolism of lipids, steroids, and other biomolecules. The enzyme exhibits a high degree of specificity, with a preference for reducing ferredoxin over other substrates. **Pathways and Functions** FDXR is involved in several key pathways, including: 1. **Electron Transport from NADPH to Ferredoxin**: FDXR facilitates the transfer of electrons from NADPH to ferredoxin, enabling the generation of energy for cellular processes. 2. **Cholesterol Metabolic Process**: FDXR plays a role in the metabolism of cholesterol, facilitating the conversion of cholesterol into bile acids. 3. **Cytochrome P450 System**: FDXR is a key component of the cytochrome P450 system, which is responsible for the metabolism of lipids, steroids, and other biomolecules. 4. **Steroid Biosynthesis**: FDXR is involved in the biosynthesis of steroid hormones, including cortisol, aldosterone, and sex hormones. 5. **Mitochondrial Iron-Sulfur Cluster Biogenesis**: FDXR is required for the assembly of iron-sulfur clusters in mitochondria, which are essential for energy production. **Clinical Significance** Alterations in FDXR function have been linked to various diseases, including: 1. **Metabolic Disorders**: Mutations in FDXR have been associated with metabolic disorders, such as insulin resistance and type 2 diabetes. 2. **Steroid Hormone Imbalance**: FDXR dysfunction has been linked to steroid hormone imbalances, including cortisol and aldosterone deficiency. 3. **Cancer**: FDXR has been implicated in the development and progression of certain cancers, including breast and prostate cancer. 4. **Neurological Disorders**: FDXR has been linked to neurological disorders, including Parkinson's disease and Alzheimer's disease. In conclusion, FDXR is a critical enzyme involved in various cellular processes, including electron transport, metabolic disorders, and steroid hormone biosynthesis. Its dysfunction has been linked to various diseases, highlighting the importance of FDXR in maintaining human health. Further research is needed to fully understand the role of FDXR in human disease and to develop effective therapeutic strategies for the treatment of FDXR-related disorders.

Genular Protein ID: 4073099859

Symbol: ADRO_HUMAN

Name: NADPH:adrenodoxin oxidoreductase, mitochondrial

UniProtKB Accession Codes:

P22570 B4DDI7 B4DHX5 B4DQQ4 B4DX24 B7Z7G2 E7EQC1 Q13716 Q4PJI0 Q9BU12

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CTD 1 ChEBI 16 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 1 EMBL 14 Ensembl 1 ExpressionAtlas 1 GO 9 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 4 RefSeq 7 Rhea 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2845396

Title: Human adrenodoxin reductase: two mRNAs encoded by a single gene on chromosome 17cen-->q25 are expressed in steroidogenic tissues.

PubMed ID: 2845396

DOI: 10.1073/pnas.85.19.7104

PubMed ID: 2236061

Title: Cloning and sequence of the human adrenodoxin reductase gene.

PubMed ID: 2236061

DOI: 10.1073/pnas.87.21.8516

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28965846

Title: FDXR Mutations Cause Sensorial Neuropathies and Expand the Spectrum of Mitochondrial Fe-S-Synthesis Diseases.

PubMed ID: 28965846

DOI: 10.1016/j.ajhg.2017.09.007

Sequence Information:

  • Length: 491
  • Mass: 53837
  • Checksum: 15D07E714F592C9D
  • Sequence:
    • MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH 
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP 
ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV 
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE 
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS 
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI 
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM 
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV 
DPQEMLRLLG H

Genular Protein ID: 3779636465

Symbol: A0A0A0MSZ4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSZ4

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 2 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 522
  • Mass: 57342
  • Checksum: 8DD435A53127363B
  • Sequence:
    • MASRCWRWWG WSAWPRTRLP PAGSTPTFGG SDEVRDPANA KALRNKRRRM QVRVKLGKFQ 
LLLDIQEKTP QICVVGSGPA GFYTAQHLLK HPQAHVDIYE KQPVPFGLVR FGVAPDHPEV 
KNVINTFTQT AHSGRCAFWG NVEVGRDVTV PELQEAYHAV VLSYGAEDHR ALEIPGEELP 
GVCSARAFVG WYNGLPENQE LEPDLSCDTA VILGQGNVAL DVARILLTPP EHLERTDITK 
AALGVLRQSR VKTVWLVGRR GPLQVAFTIK ELREMIQLPG ARPILDPVDF LGLQDKIKEV 
PRPRKRLTEL LLRTATEKPG PAEAARQASA SRAWGLRFFR SPQQVLPSPD GRRAAGVRLA 
VTRLEGVDEA TRAVPTGDME DLPCGLVLSS IGYKSRPVDP SVPFDSKLGV IPNVEGRVMD 
VPGLYCSGWV KRGPTGVIAT TMTDSFLTGQ MLLQDLKAGL LPSGPRPGYA AIQALLSSRG 
VRPVSFSDWE KLDAEEVARG QGTGKPREKL VDPQEMLRLL GH

Genular Protein ID: 190740334

Symbol: A0A0A0MT64_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MT64

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 2 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 534
  • Mass: 58218
  • Checksum: 3421AC07178E5A11
  • Sequence:
    • MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKR 
VEALCSQPRV LNSPALSGEG EDLGASQPLS LGPTSCHPVP QQHPQAHVDI YEKQPVPFGL 
VRFGVAPDHP EVKNVINTFT QTAHSGRCAF WGNVEVGRDV TVPELQEAYH AVVLSYGAED 
HRALEIPGEE LPGVCSARAF VGWYNGLPEN QELEPDLSCD TAVILGQGNV ALDVARILLT 
PPEHLERTDI TKAALGVLRQ SRVKTVWLVG RRGPLQVAFT IKELREMIQL PGARPILDPV 
DFLGLQDKIK EVPRPRKRLT ELLLRTATEK PGPAEAARQA SASRAWGLRF FRSPQQVLPS 
PDGRRAAGVR LAVTRLEGVD EATRAVPTGD MEDLPCGLVL SSIGYKSRPV DPSVPFDSKL 
GVIPNVEGRV MDVPGLYCSG WVKRGPTGVI ATTMTDSFLT GQMLLQDLKA GLLPSGPRPG 
YAAIQALLSS RGVRPVSFSD WEKLDAEEVA RGQGTGKPRE KLVDPQEMLR LLGH

Genular Protein ID: 1452826449

Symbol: A0A0C4DFN8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DFN8

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 3 KEGG 1 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 2 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 491
  • Mass: 53809
  • Checksum: 85865BAA2276D2B2
  • Sequence:
    • MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH 
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP 
ELQEAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV 
ILGQGNVALD VARILLTPPE HLERTDITKA ALGVLRQSRV KTVWLVGRRG PLQVAFTIKE 
LREMIQLPGA RPILDPVDFL GLQDKIKEVP RPRKRLTELL LRTATEKPGP AEAARQASAS 
RAWGLRFFRS PQQVLPSPDG RRAAGVRLAV TRLEGVDEAT RAVPTGDMED LPCGLVLSSI 
GYKSRPVDPS VPFDSKLGVI PNVEGRVMDV PGLYCSGWVK RGPTGVIATT MTDSFLTGQM 
LLQDLKAGLL PSGPRPGYAA IQALLSSRGV RPVSFSDWEK LDAEEVARGQ GTGKPREKLV 
DPQEMLRLLG H

Genular Protein ID: 246745800

Symbol: A0A0C4DGN7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DGN7

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 497
  • Mass: 54451
  • Checksum: 3913D33DC97A648C
  • Sequence:
    • MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH 
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP 
ELQEAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV 
ILGQGNVALD VARILLTPPE HLEALLLCQR TDITKAALGV LRQSRVKTVW LVGRRGPLQV 
AFTIKELREM IQLPGARPIL DPVDFLGLQD KIKEVPRPRK RLTELLLRTA TEKPGPAEAA 
RQASASRAWG LRFFRSPQQV LPSPDGRRAA GVRLAVTRLE GVDEATRAVP TGDMEDLPCG 
LVLSSIGYKS RPVDPSVPFD SKLGVIPNVE GRVMDVPGLY CSGWVKRGPT GVIATTMTDS 
FLTGQMLLQD LKAGLLPSGP RPGYAAIQAL LSSRGVRPVS FSDWEKLDAE EVARGQGTGK 
PREKLVDPQE MLRLLGH

Genular Protein ID: 2257473634

Symbol: A0A0A0MTR6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MTR6

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 483
  • Mass: 52891
  • Checksum: 1A87397758EC1AEE
  • Sequence:
    • MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH 
PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK TAHSGRCAFW GNVEVGRDVT VPELQEAYHA 
VVLSYGAEDH RALEIPGEEL PGVCSARAFV GWYNGLPENQ ELEPDLSCDT AVILGQGNVA 
LDVARILLTP PEHLERTDIT KAALGVLRQS RVKTVWLVGR RGPLQVAFTI KELREMIQLP 
GARPILDPVD FLGLQDKIKE VPRPRKRLTE LLLRTATEKP GPAEAARQAS ASRAWGLRFF 
RSPQQVLPSP DGRRAAGVRL AVTRLEGVDE ATRAVPTGDM EDLPCGLVLS SIGYKSRPVD 
PSVPFDSKLG VIPNVEGRVM DVPGLYCSGW VKRGPTGVIA TTMTDSFLTG QMLLQDLKAG 
LLPSGPRPGY AAIQALLSSR GVRPVSFSDW EKLDAEEVAR GQGTGKPREK LVDPQEMLRL 
LGH

Genular Protein ID: 307925756

Symbol: A0A0A0MTN9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MTN9

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 15 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 439
  • Mass: 48028
  • Checksum: B08EAAC1FCBF672F
  • Sequence:
    • MEDKDREHPQ AHVDIYEKQP VPFGLVRFGV APDHPEVKNV INTFTQTAHS GRCAFWGNVE 
VGRDVTVPEL QEAYHAVVLS YGAEDHRALE IPGEELPGVC SARAFVGWYN GLPENQELEP 
DLSCDTAVIL GQGNVALDVA RILLTPPEHL ERTDITKAAL GVLRQSRVKT VWLVGRRGPL 
QVAFTIKELR EMIQLPGARP ILDPVDFLGL QDKIKEVPRP RKRLTELLLR TATEKPGPAE 
AARQASASRA WGLRFFRSPQ QVLPSPDGRR AAGVRLAVTR LEGVDEATRA VPTGDMEDLP 
CGLVLSSIGY KSRPVDPSVP FDSKLGVIPN VEGRVMDVPG LYCSGWVKRG PTGVIATTMT 
DSFLTGQMLL QDLKAGLLPS GPRPGYAAIQ ALLSSRGVRP VSFSDWEKLD AEEVARGQGT 
GKPREKLVDP QEMLRLLGH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.