Details for: FOSL2

Gene ID: 2355

Symbol: FOSL2

Ensembl ID: ENSG00000075426

Description: FOS like 2, AP-1 transcription factor subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 302.9987
    Cell Significance Index: -47.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 177.2962
    Cell Significance Index: -44.9700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 99.9105
    Cell Significance Index: -47.1700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 95.4629
    Cell Significance Index: -38.7800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 86.2972
    Cell Significance Index: -44.3900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 70.1169
    Cell Significance Index: -47.0500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 41.5347
    Cell Significance Index: -39.6600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.2171
    Cell Significance Index: -47.1200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.6974
    Cell Significance Index: -44.7300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.0120
    Cell Significance Index: -47.4000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.8320
    Cell Significance Index: -33.2700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.3446
    Cell Significance Index: -22.6400
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 5.7574
    Cell Significance Index: 12.9800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 5.2045
    Cell Significance Index: 139.4600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.9509
    Cell Significance Index: 34.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.8396
    Cell Significance Index: 95.5600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.8179
    Cell Significance Index: 1641.4600
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.7516
    Cell Significance Index: 12.5800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6614
    Cell Significance Index: 204.2900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.6161
    Cell Significance Index: 43.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5784
    Cell Significance Index: 284.5300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5569
    Cell Significance Index: 93.4700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.4687
    Cell Significance Index: 31.8200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.4262
    Cell Significance Index: 155.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4113
    Cell Significance Index: 63.9700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.3106
    Cell Significance Index: 37.7600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0692
    Cell Significance Index: 29.8800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.0334
    Cell Significance Index: 6.3600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.0246
    Cell Significance Index: 29.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9763
    Cell Significance Index: 134.0700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9700
    Cell Significance Index: 72.2900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.9398
    Cell Significance Index: 22.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8434
    Cell Significance Index: 39.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7344
    Cell Significance Index: 72.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7330
    Cell Significance Index: 324.0900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6939
    Cell Significance Index: 88.9500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6477
    Cell Significance Index: 49.7100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.6401
    Cell Significance Index: 11.8300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.6223
    Cell Significance Index: 7.0700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6220
    Cell Significance Index: 14.3700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.5879
    Cell Significance Index: 15.7300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4546
    Cell Significance Index: 29.3300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4528
    Cell Significance Index: 73.6400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4241
    Cell Significance Index: 3.9100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.4165
    Cell Significance Index: 5.9900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4004
    Cell Significance Index: 218.6600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3498
    Cell Significance Index: 658.6200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3399
    Cell Significance Index: 24.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3295
    Cell Significance Index: 66.0900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.3103
    Cell Significance Index: 4.6500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2590
    Cell Significance Index: 6.4800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2485
    Cell Significance Index: 12.9500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1894
    Cell Significance Index: 6.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1862
    Cell Significance Index: 118.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1406
    Cell Significance Index: 18.1700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0705
    Cell Significance Index: 13.9800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0654
    Cell Significance Index: 12.4400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0648
    Cell Significance Index: 44.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0602
    Cell Significance Index: 27.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0378
    Cell Significance Index: 69.6500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0319
    Cell Significance Index: 49.0900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0041
    Cell Significance Index: 0.1100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0037
    Cell Significance Index: -1.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0180
    Cell Significance Index: -0.8400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0235
    Cell Significance Index: -31.9100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0268
    Cell Significance Index: -19.6400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0301
    Cell Significance Index: -0.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0318
    Cell Significance Index: -3.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0377
    Cell Significance Index: -28.5600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0388
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0603
    Cell Significance Index: -44.6800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0611
    Cell Significance Index: -0.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0792
    Cell Significance Index: -13.5200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0803
    Cell Significance Index: -50.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0831
    Cell Significance Index: -46.8600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1116
    Cell Significance Index: -5.6400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1298
    Cell Significance Index: -18.8700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1311
    Cell Significance Index: -37.7100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1520
    Cell Significance Index: -1.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1583
    Cell Significance Index: -2.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2255
    Cell Significance Index: -25.8300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2380
    Cell Significance Index: -50.1300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2589
    Cell Significance Index: -30.1700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3454
    Cell Significance Index: -40.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4005
    Cell Significance Index: -41.7000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4057
    Cell Significance Index: -27.2800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.4088
    Cell Significance Index: -2.5400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4145
    Cell Significance Index: -13.2800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4902
    Cell Significance Index: -5.0700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5027
    Cell Significance Index: -30.8200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5054
    Cell Significance Index: -40.0300
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.5256
    Cell Significance Index: -8.4800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.6334
    Cell Significance Index: -25.9500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.6543
    Cell Significance Index: -9.8600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6847
    Cell Significance Index: -17.6000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7066
    Cell Significance Index: -25.9400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.7233
    Cell Significance Index: -44.4600
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.7294
    Cell Significance Index: -7.6200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.7315
    Cell Significance Index: -41.0500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7540
    Cell Significance Index: -47.5200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FOSL2 is a transcription factor that belongs to the AP-1 family of proteins, which are known to regulate gene expression in response to a variety of stimuli, including growth factors, cytokines, and stress signals. The FOSL2 protein is a subunit of the AP-1 complex, which is composed of different members, including FOS, JUN, and ATF. FOSL2 is specifically involved in the regulation of gene expression in response to various signals, including those that promote cell growth, differentiation, and survival. **Pathways and Functions** FOSL2 is involved in several cellular pathways, including: 1. **Cell growth and proliferation**: FOSL2 regulates the expression of genes involved in cell growth and proliferation, such as those involved in the cell cycle and DNA synthesis. 2. **Differentiation**: FOSL2 is involved in the regulation of gene expression that promotes cell differentiation, such as the differentiation of T cells and B cells. 3. **Survival**: FOSL2 regulates the expression of genes involved in cell survival, such as those that promote anti-apoptotic signaling pathways. 4. **Inflammatory response**: FOSL2 is involved in the regulation of gene expression that promotes the inflammatory response, such as the expression of genes involved in the production of cytokines and chemokines. **Clinical Significance** FOSL2 has been implicated in several diseases, including: 1. **Immune disorders**: FOSL2 has been associated with immune disorders, such as autoimmune diseases and immunodeficiency disorders. 2. **Cancer**: FOSL2 has been implicated in the development and progression of various types of cancer, including leukemia and lymphoma. 3. **Cardiovascular disease**: FOSL2 has been associated with cardiovascular disease, including atherosclerosis and cardiac hypertrophy. 4. **Neurological disorders**: FOSL2 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, FOSL2 is a gene that plays a crucial role in regulating cell growth, differentiation, and survival, which are essential for the proper functioning of the immune system. Its dysregulation has been implicated in several diseases, highlighting the importance of further research into the functions and clinical significance of FOSL2. **Significantly expressed cells** * Skeletal muscle satellite stem cell * Decidual natural killer cell * Human, conjunctival epithelial cell * Glandular epithelial cell * Bladder urothelial cell * Pancreatic acinar cell * Cerebral cortex endothelial cell * Cortical cell of adrenal gland * Foveolar cell of stomach * Corneal epithelial cell **Proteins** * FOSL2_HUMAN (Fos-related antigen 2) * Q9H5M2_HUMAN

Genular Protein ID: 2581031366

Symbol: FOSL2_HUMAN

Name: Fos-related antigen 2

UniProtKB Accession Codes:

P15408 B2RD58 B3KP27 B4DYV4 Q6FG46

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 56 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2107490

Title: Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.

PubMed ID: 2107490

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 36197437

Title: FOSL2 truncating variants in the last exon cause a neurodevelopmental disorder with scalp and enamel defects.

PubMed ID: 36197437

DOI: 10.1016/j.gim.2022.09.002

Sequence Information:

  • Length: 326
  • Mass: 35193
  • Checksum: F61738BE23C5026F
  • Sequence:
    • MYQDYPGNFD TSSRGSSGSP AHAESYSSGG GGQQKFRVDM PGSGSAFIPT INAITTSQDL 
QWMVQPTVIT SMSNPYPRSH PYSPLPGLAS VPGHMALPRP GVIKTIGTTV GRRRRDEQLS 
PEEEEKRRIR RERNKLAAAK CRNRRRELTE KLQAETEELE EEKSGLQKEI AELQKEKEKL 
EFMLVAHGPV CKISPEERRS PPAPGLQPMR SGGGSVGAVV VKQEPLEEDS PSSSSAGLDK 
AQRSVIKPIS IAGGFYGEEP LHTPIVVTST PAVTPGTSNL VFTYPSVLEQ ESPASPSESC 
SKAHRRSSSS GDQSSDSLNS PTLLAL

Genular Protein ID: 1004375905

Symbol: Q9H5M2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9H5M2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 23950983

Title: Direct detection of alternative open reading frames translation products in human significantly expands the proteome.

PubMed ID: 23950983

DOI: 10.1371/journal.pone.0070698

Sequence Information:

  • Length: 122
  • Mass: 12957
  • Checksum: 701BAD1E6D421AD6
  • Sequence:
    • MSVGLDLPQM LPGSPSPSLK EAFAEDGEAG EGGGRPSLEW RLQQLLPQHP LSLSWLLTSP 
QGTGPFLPSV VICHLLDQVL SLLHSPVPTP VHSSGPGSKQ AVNSWPELSL WLVAHAPFLV 
VC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.