Details for: GAB1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac neuron (CL0010022)
Fold Change: 3.98
Marker Score: 4963 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 3.46
Marker Score: 8276 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 3.45
Marker Score: 77014 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 2.68
Marker Score: 2198 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.55
Marker Score: 2933 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.4
Marker Score: 51252 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.4
Marker Score: 2648 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.38
Marker Score: 1321 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 2.34
Marker Score: 6717 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.27
Marker Score: 9482.5 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.25
Marker Score: 1260 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.23
Marker Score: 11710 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.15
Marker Score: 4142 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.11
Marker Score: 1623 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.03
Marker Score: 1185 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.97
Marker Score: 1175 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.96
Marker Score: 1144 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.79
Marker Score: 9632 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.79
Marker Score: 3934 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 1.77
Marker Score: 2094 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.76
Marker Score: 28214 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.76
Marker Score: 2172 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.76
Marker Score: 1405 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.67
Marker Score: 2252 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.61
Marker Score: 5714 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.59
Marker Score: 784 - Cell Name: contractile cell (CL0000183)
Fold Change: 1.57
Marker Score: 853 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.54
Marker Score: 95007.5 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.54
Marker Score: 1466 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.52
Marker Score: 30280 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.44
Marker Score: 3401 - Cell Name: fat cell (CL0000136)
Fold Change: 1.41
Marker Score: 789 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.41
Marker Score: 979 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.4
Marker Score: 1208 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.4
Marker Score: 408 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.38
Marker Score: 432 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.36
Marker Score: 1651 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.33
Marker Score: 1438 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.32
Marker Score: 870 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.32
Marker Score: 1496 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.31
Marker Score: 48312.5 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.29
Marker Score: 20203.5 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.28
Marker Score: 636 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.28
Marker Score: 1132 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.2
Marker Score: 453 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.2
Marker Score: 10300 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.17
Marker Score: 377 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.17
Marker Score: 1014 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.17
Marker Score: 4891 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.15
Marker Score: 3781.5 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.14
Marker Score: 411.5 - Cell Name: endocardial cell (CL0002350)
Fold Change: 1.07
Marker Score: 606 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.05
Marker Score: 332 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.04
Marker Score: 1114 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.03
Marker Score: 39094 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.02
Marker Score: 205 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1
Marker Score: 3363 - Cell Name: microglial cell (CL0000129)
Fold Change: 1
Marker Score: 1824 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1
Marker Score: 480 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71737 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1
Marker Score: 362 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47960.5 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.99
Marker Score: 1408 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.99
Marker Score: 17603 - Cell Name: neural cell (CL0002319)
Fold Change: 0.99
Marker Score: 478 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.99
Marker Score: 285 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30400 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.98
Marker Score: 1182 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.98
Marker Score: 2447 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.97
Marker Score: 248 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.97
Marker Score: 10008.5 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 497 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.96
Marker Score: 1955 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.96
Marker Score: 452 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.95
Marker Score: 1005 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.95
Marker Score: 357 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.95
Marker Score: 5735 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2406 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.94
Marker Score: 1520 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.93
Marker Score: 3301 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.93
Marker Score: 1230.5 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.92
Marker Score: 12196.5 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.91
Marker Score: 2484 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2721 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.89
Marker Score: 320 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.89
Marker Score: 534 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.88
Marker Score: 419 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5295 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.87
Marker Score: 2137 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.87
Marker Score: 5563 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.86
Marker Score: 569 - Cell Name: IgM plasma cell (CL0000986)
Fold Change: 0.86
Marker Score: 301 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.86
Marker Score: 361 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 0.86
Marker Score: 1030 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4868 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.84
Marker Score: 221 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.83
Marker Score: 803 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.83
Marker Score: 482 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.83
Marker Score: 631.5 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.82
Marker Score: 327.5
Hover over a box to see details here...
Hover over a box to see details here...
Hover over a box to see details here...
Other Information
Genular Protein ID: 437945626
Symbol: GAB1_HUMAN
Name: GRB2-associated-binding protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8596638
Title: A Grb2-associated docking protein in EGF- and insulin-receptor signalling.
PubMed ID: 8596638
DOI: 10.1038/379560a0
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12486104
Title: Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.
PubMed ID: 12486104
DOI: 10.1084/jem.20021405
PubMed ID: 12475979
Title: Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1.
PubMed ID: 12475979
PubMed ID: 15010462
Title: Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.
PubMed ID: 15010462
PubMed ID: 15863030
Title: Cellular signaling by fibroblast growth factor receptors.
PubMed ID: 15863030
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 29408807
Title: Modifier variant of METTL13 suppresses human GAB1-associated profound deafness.
PubMed ID: 29408807
DOI: 10.1172/jci97350
Sequence Information:
- Length: 694
- Mass: 76616
- Checksum: E0FAC78772B6677B
- Sequence:
MSGGEVVCSG WLRKSPPEKK LKRYAWKRRW FVLRSGRLTG DPDVLEYYKN DHAKKPIRII DLNLCQQVDA GLTFNKKEFE NSYIFDINTI DRIFYLVADS EEEMNKWVRC ICDICGFNPT EEDPVKPPGS SLQAPADLPL AINTAPPSTQ ADSSSATLPP PYQLINVPPH LETLGIQEDP QDYLLLINCQ SKKPEPTRTH ADSAKSTSSE TDCNDNVPSH KNPASSQSKH GMNGFFQQQM IYDSPPSRAP SASVDSSLYN LPRSYSHDVL PKVSPSSTEA DGELYVFNTP SGTSSVETQM RHVSISYDIP PTPGNTYQIP RTFPEGTLGQ TSKLDTIPDI PPPRPPKPHP AHDRSPVETC SIPRTASDTD SSYCIPTAGM SPSRSNTIST VDLNKLRKDA SSQDCYDIPR AFPSDRSSSL EGFHNHFKVK NVLTVGSVSS EELDENYVPM NPNSPPRQHS SSFTEPIQEA NYVPMTPGTF DFSSFGMQVP PPAHMGFRSS PKTPPRRPVP VADCEPPPVD RNLKPDRKVK PAPLEIKPLP EWEELQAPVR SPITRSFARD SSRFPMSPRP DSVHSTTSSS DSHDSEENYV PMNPNLSSED PNLFGSNSLD GGSSPMIKPK GDKQVEYLDL DLDSGKSTPP RKQKSSGSGS SVADERVDYV VVDQQKTLAL KSTREAWTDG RQSTESETPA KSVK
Genular Protein ID: 837024928
Symbol: Q9HA84_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 275
- Mass: 30334
- Checksum: 3E305D407169FD1F
- Sequence:
MNPNSPPRQH SSSFTEPIQE ANYVPMTPGT FDFSSFGMQV PPPAHMGFRS SPKTPPRRPV PVADCEPPPV DRNLKPDRKG QSPKILRLKP HGLERTDSQT IGDFATRRKV KPAPLEIKPL PEWEELQAPV RSPITRSFAR DSSRFPMSPR PDSVHSTTSS SDSHDSEENY VPMNPNLSSE DPNLFGSNSL DGGSSPMIKP KGDKQVEYLD LDLDSGKSTP PRKQKSSSSG SSVADERVDY VVVDQQKTLA LKSTREAWTD GRQSTESETP AKSVK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.