Details for: DNAI1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 10.4740
Cell Significance Index: -10.0000 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.8972
Cell Significance Index: 8.8900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.8424
Cell Significance Index: 37.2600 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.8116
Cell Significance Index: 19.6600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.7109
Cell Significance Index: 26.9200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4751
Cell Significance Index: 26.6600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.3343
Cell Significance Index: 7.3200 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.3332
Cell Significance Index: 3.2600 - Cell Name: helper T cell (CL0000912)
Fold Change: 0.3188
Cell Significance Index: 4.5300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2704
Cell Significance Index: 54.2500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1389
Cell Significance Index: 96.0900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1365
Cell Significance Index: 74.5200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0460
Cell Significance Index: 16.5000 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.0427
Cell Significance Index: 0.7300 - Cell Name: glioblast (CL0000030)
Fold Change: 0.0414
Cell Significance Index: 0.2600 - Cell Name: radial glial cell (CL0000681)
Fold Change: 0.0303
Cell Significance Index: 0.1800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0134
Cell Significance Index: 25.2300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0128
Cell Significance Index: 23.5800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0033
Cell Significance Index: 5.0500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0013
Cell Significance Index: 0.8300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0030
Cell Significance Index: -0.2100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0067
Cell Significance Index: -9.1200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0076
Cell Significance Index: -1.5100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0120
Cell Significance Index: -8.9100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0130
Cell Significance Index: -9.5600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0162
Cell Significance Index: -12.2600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0177
Cell Significance Index: -10.0100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0197
Cell Significance Index: -12.3000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0223
Cell Significance Index: -10.1200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0258
Cell Significance Index: -0.3700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0264
Cell Significance Index: -7.6000 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: -0.0359
Cell Significance Index: -0.3300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0459
Cell Significance Index: -6.6700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0490
Cell Significance Index: -8.8300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0563
Cell Significance Index: -11.8600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0617
Cell Significance Index: -1.3100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0666
Cell Significance Index: -9.1500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0717
Cell Significance Index: -12.2400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0777
Cell Significance Index: -9.5600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0871
Cell Significance Index: -11.2600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0946
Cell Significance Index: -2.6400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0960
Cell Significance Index: -10.0000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0963
Cell Significance Index: -9.8400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0982
Cell Significance Index: -11.4400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0984
Cell Significance Index: -11.2700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0997
Cell Significance Index: -7.6500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1100
Cell Significance Index: -12.9700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1256
Cell Significance Index: -9.9500 - Cell Name: ciliated cell (CL0000064)
Fold Change: -0.1302
Cell Significance Index: -1.4100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1331
Cell Significance Index: -8.3900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1385
Cell Significance Index: -10.3300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1560
Cell Significance Index: -9.5900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1626
Cell Significance Index: -7.0700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1716
Cell Significance Index: -6.0100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1875
Cell Significance Index: -9.8500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1975
Cell Significance Index: -10.2900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1979
Cell Significance Index: -4.1300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2029
Cell Significance Index: -5.7900 - Cell Name: neuron (CL0000540)
Fold Change: -0.2110
Cell Significance Index: -2.0000 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.2148
Cell Significance Index: -1.8600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2187
Cell Significance Index: -7.1600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2189
Cell Significance Index: -9.9200 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2194
Cell Significance Index: -5.0700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2198
Cell Significance Index: -7.0000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2249
Cell Significance Index: -10.5700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2260
Cell Significance Index: -11.7400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2463
Cell Significance Index: -6.3300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2498
Cell Significance Index: -9.1700 - Cell Name: neural cell (CL0002319)
Fold Change: -0.2503
Cell Significance Index: -2.9200 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.2903
Cell Significance Index: -3.6200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2947
Cell Significance Index: -5.0500 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: -0.2957
Cell Significance Index: -2.3200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2973
Cell Significance Index: -10.3300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3063
Cell Significance Index: -7.6400 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.3067
Cell Significance Index: -9.7000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.3186
Cell Significance Index: -11.2000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3272
Cell Significance Index: -4.1300 - Cell Name: ependymal cell (CL0000065)
Fold Change: -0.3335
Cell Significance Index: -3.9300 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.3343
Cell Significance Index: -2.2600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3373
Cell Significance Index: -6.6700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3373
Cell Significance Index: -9.1800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3393
Cell Significance Index: -7.3300 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3439
Cell Significance Index: -10.1300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.3516
Cell Significance Index: -7.3600 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.3607
Cell Significance Index: -9.1900 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3730
Cell Significance Index: -6.4500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.3765
Cell Significance Index: -9.0300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3792
Cell Significance Index: -10.9300 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -0.3838
Cell Significance Index: -2.7900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3905
Cell Significance Index: -7.8400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3907
Cell Significance Index: -11.2000 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.3921
Cell Significance Index: -5.4400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3942
Cell Significance Index: -10.5300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.4196
Cell Significance Index: -8.9700 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.4214
Cell Significance Index: -8.2400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4241
Cell Significance Index: -11.3500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.4250
Cell Significance Index: -10.6300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4266
Cell Significance Index: -11.4300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.4290
Cell Significance Index: -11.2800 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.4302
Cell Significance Index: -5.9000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 630330321
Symbol: DNAI1_HUMAN
Name: Dynein axonemal intermediate chain 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10577904
Title: Loss-of-function mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia.
PubMed ID: 10577904
DOI: 10.1086/302683
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12509440
Title: Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.
PubMed ID: 12509440
PubMed ID: 23664119
Title: Molecular defects in the motor adaptor BICD2 cause proximal spinal muscular atrophy with autosomal-dominant inheritance.
PubMed ID: 23664119
PubMed ID: 27120127
Title: Mutations in GAS8, a gene encoding a nexin-dynein regulatory complex subunit, cause primary ciliary dyskinesia with axonemal disorganization.
PubMed ID: 27120127
DOI: 10.1002/humu.23005
PubMed ID: 33263282
Title: Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins.
PubMed ID: 33263282
DOI: 10.7554/elife.58662
PubMed ID: 33139725
Title: CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.
PubMed ID: 33139725
PubMed ID: 11231901
Title: Axonemal dynein intermediate-chain gene (DNAI1) mutations result in situs inversus and primary ciliary dyskinesia (Kartagener syndrome).
PubMed ID: 11231901
DOI: 10.1086/319511
PubMed ID: 25186273
Title: Ciliary beat pattern and frequency in genetic variants of primary ciliary dyskinesia.
PubMed ID: 25186273
Sequence Information:
- Length: 699
- Mass: 79283
- Checksum: F7E2CF9D09A1F8BD
- Sequence:
MIPASAKAPH KQPHKQSISI GRGTRKRDED SGTEVGEGTD EWAQSKATVR PPDQLELTDA ELKEEFTRIL TANNPHAPQN IVRYSFKEGT YKPIGFVNQL AVHYTQVGNL IPKDSDEGRR QHYRDELVAG SQESVKVISE TGNLEEDEEP KELETEPGSQ TDVPAAGAAE KVTEEELMTP KQPKERKLTN QFNFSERASQ TYNNPVRDRE CQTEPPPRTN FSATANQWEI YDAYVEELEK QEKTKEKEKA KTPVAKKSGK MAMRKLTSME SQTDDLIKLS QAAKIMERMV NQNTYDDIAQ DFKYYDDAAD EYRDQVGTLL PLWKFQNDKA KRLSVTALCW NPKYRDLFAV GYGSYDFMKQ SRGMLLLYSL KNPSFPEYMF SSNSGVMCLD IHVDHPYLVA VGHYDGNVAI YNLKKPHSQP SFCSSAKSGK HSDPVWQVKW QKDDMDQNLN FFSVSSDGRI VSWTLVKRKL VHIDVIKLKV EGSTTEVPEG LQLHPVGCGT AFDFHKEIDY MFLVGTEEGK IYKCSKSYSS QFLDTYDAHN MSVDTVSWNP YHTKVFMSCS SDWTVKIWDH TIKTPMFIYD LNSAVGDVAW APYSSTVFAA VTTDGKAHIF DLAINKYEAI CNQPVAAKKN RLTHVQFNLI HPIIIVGDDR GHIISLKLSP NLRKMPKEKK GQEVQKGPAV EIAKLDKLLN LVREVKIKT
Genular Protein ID: 1535556040
Symbol: A0A087WWV9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 703
- Mass: 79760
- Checksum: EF6A6477C4C17A23
- Sequence:
MIPASAKAPH KQPHKQSISI GRGTRKRDED SGTEVGEGTD EWAQSKATVR PPDQLELTDA ELKEEFTRIL TANNPHAPQN IVRYSFKEGT YKPIGFVNQL AVHYTQVGNL IPKDSDEGRR QHYRDELVAV SYQGSQESVK VISETGNLEE DEEPKELETE PGSQTDVPAA GAAEKVTEEE LMTPKQPKER KLTNQFNFSE RASQTYNNPV RDRECQTEPP PRTNFSATAN QWEIYDAYVE ELEKQEKTKE KEKAKTPVAK KSGKMAMRKL TSMESQTDDL IKLSQAAKIM ERMVNQNTYD DIAQDFKYYD DAADEYRDQV GTLLPLWKFQ NDKAKRLSVT ALCWNPKYRD LFAVGYGSYD FMKQSRGMLL LYSLKNPSFP EYMFSSNSGV MCLDIHVDHP YLVAVGHYDG NVAIYNLKKP HSQPSFCSSA KSGKHSDPVW QVKWQKDDMD QNLNFFSVSS DGRIVSWTLV KRKLVHIDVI KLKVEGSTTE VPEGLQLHPV GCGTAFDFHK EIDYMFLVGT EEGKIYKCSK SYSSQFLDTY DAHNMSVDTV SWNPYHTKVF MSCSSDWTVK IWDHTIKTPM FIYDLNSAVG DVAWAPYSST VFAAVTTDGK AHIFDLAINK YEAICNQPVA AKKNRLTHVQ FNLIHPIIIV GDDRGHIISL KLSPNLRKMP KEKKGQEVQK GPAVEIAKLD KLLNLVREVK IKT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.