Details for: POLL

Gene ID: 27343

Symbol: POLL

Ensembl ID: ENSG00000166169

Description: DNA polymerase lambda

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 89.5238
    Cell Significance Index: -13.9300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 50.1886
    Cell Significance Index: -12.7300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 34.6579
    Cell Significance Index: -14.0800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 33.2964
    Cell Significance Index: -15.7200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 30.3275
    Cell Significance Index: -15.6000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 14.8207
    Cell Significance Index: -14.1500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 11.6630
    Cell Significance Index: -14.3800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.2914
    Cell Significance Index: -14.1800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.9913
    Cell Significance Index: -15.7500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.8451
    Cell Significance Index: -11.8100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.1521
    Cell Significance Index: 134.2600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0988
    Cell Significance Index: 992.1400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8430
    Cell Significance Index: 50.6100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8412
    Cell Significance Index: 91.5000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.7380
    Cell Significance Index: 11.8400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7258
    Cell Significance Index: 118.0500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4701
    Cell Significance Index: 94.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4606
    Cell Significance Index: 91.4100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4441
    Cell Significance Index: 30.7100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4086
    Cell Significance Index: 18.5200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4083
    Cell Significance Index: 40.3900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4059
    Cell Significance Index: 21.0900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3643
    Cell Significance Index: 7.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3445
    Cell Significance Index: 4.7000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3349
    Cell Significance Index: 9.6500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3042
    Cell Significance Index: 57.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2789
    Cell Significance Index: 50.2800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2762
    Cell Significance Index: 17.4100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2734
    Cell Significance Index: 7.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2651
    Cell Significance Index: 12.3600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2633
    Cell Significance Index: 143.7700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2554
    Cell Significance Index: 91.6200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1811
    Cell Significance Index: 24.8700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1544
    Cell Significance Index: 8.0400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1535
    Cell Significance Index: 18.8800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.1331
    Cell Significance Index: 3.4000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1250
    Cell Significance Index: 14.7400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1187
    Cell Significance Index: 52.4700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1181
    Cell Significance Index: 15.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1066
    Cell Significance Index: 8.1800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1053
    Cell Significance Index: 5.5300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0934
    Cell Significance Index: 6.0300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0870
    Cell Significance Index: 2.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0855
    Cell Significance Index: 14.6100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0820
    Cell Significance Index: 2.0500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0810
    Cell Significance Index: 2.3800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0797
    Cell Significance Index: 4.4700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0748
    Cell Significance Index: 2.6300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0536
    Cell Significance Index: 3.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0521
    Cell Significance Index: 2.4500
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.0485
    Cell Significance Index: 0.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0470
    Cell Significance Index: 32.5100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0339
    Cell Significance Index: 4.3400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0273
    Cell Significance Index: 51.4000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0229
    Cell Significance Index: 14.5600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0198
    Cell Significance Index: 0.5200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0084
    Cell Significance Index: 15.5200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0041
    Cell Significance Index: 6.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0021
    Cell Significance Index: 0.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0017
    Cell Significance Index: 0.1300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0041
    Cell Significance Index: -0.1800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0061
    Cell Significance Index: -8.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0080
    Cell Significance Index: -5.8400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0092
    Cell Significance Index: -6.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0115
    Cell Significance Index: -1.6700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0131
    Cell Significance Index: -0.3500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0136
    Cell Significance Index: -0.2900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0143
    Cell Significance Index: -0.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0170
    Cell Significance Index: -12.6000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0193
    Cell Significance Index: -1.9700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0234
    Cell Significance Index: -13.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0239
    Cell Significance Index: -1.6100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0279
    Cell Significance Index: -17.4000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0314
    Cell Significance Index: -0.3300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0378
    Cell Significance Index: -1.4300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0445
    Cell Significance Index: -1.2100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0462
    Cell Significance Index: -13.2800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0550
    Cell Significance Index: -0.9200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0590
    Cell Significance Index: -2.0500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0663
    Cell Significance Index: -1.3800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0719
    Cell Significance Index: -4.4200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0782
    Cell Significance Index: -8.9600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0795
    Cell Significance Index: -16.7600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0809
    Cell Significance Index: -1.8700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0868
    Cell Significance Index: -1.9000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0898
    Cell Significance Index: -1.8800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1240
    Cell Significance Index: -3.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1332
    Cell Significance Index: -13.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1679
    Cell Significance Index: -10.3000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1801
    Cell Significance Index: -14.2600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2153
    Cell Significance Index: -3.6900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2225
    Cell Significance Index: -6.3500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2254
    Cell Significance Index: -4.4000
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2810
    Cell Significance Index: -2.3600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2815
    Cell Significance Index: -8.2900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2827
    Cell Significance Index: -5.2300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2904
    Cell Significance Index: -9.2500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.2918
    Cell Significance Index: -2.3300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3051
    Cell Significance Index: -9.9900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3079
    Cell Significance Index: -4.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **DNA Polymerase Activity:** POLL exhibits 5'-to 3' DNA polymerase activity, which is essential for DNA replication and repair. 2. **5'-Deoxyribose-5-Phosphate Lyase Activity:** This activity is involved in the repair of DNA damage by removing 5'-deoxyribose-5-phosphate groups. 3. **Metal Ion Binding:** POLL binds to metal ions, such as magnesium and manganese, which are required for its enzymatic activity. 4. **DNA Binding:** POLL interacts with DNA through its C-terminal domain, facilitating its role in DNA replication and repair. **Pathways and Functions:** 1. **Base-Excision Repair (BER):** POLL is involved in the repair of DNA damage caused by oxidative stress and alkylation. 2. **Nucleotide-Excision Repair (NER):** POLL participates in the excision of bulky DNA lesions, such as those caused by UV irradiation. 3. **Homologous Recombination Repair (HRR):** POLL is required for the repair of double-strand breaks through homologous recombination. 4. **Double-Strand Break Repair via Nonhomologous End Joining (NHEJ):** POLL interacts with DNA ligases and other proteins involved in NHEJ. 5. **DNA Replication:** POLL is essential for DNA replication in germ cells and other cell types. 6. **Somatic Hypermutation of Immunoglobulin Genes:** POLL is involved in the somatic hypermutation process, which generates diversity in antibodies. **Clinical Significance:** Dysregulation of POLL has been implicated in various diseases, including: 1. **Cancer:** Impaired DNA repair mechanisms, including those involving POLL, can contribute to cancer development and progression. 2. **Genetic Disorders:** Mutations in the POLL gene can lead to genetic disorders, such as Fanconi anemia and Bloom syndrome. 3. **Immunological Disorders:** Alterations in POLL expression or function may contribute to immunological disorders, such as autoimmune diseases and immunodeficiencies. In conclusion, DNA polymerase lambda is a critical enzyme involved in maintaining genome stability through DNA repair, replication, and immunological processes. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding its mechanisms and regulation.

Genular Protein ID: 527201935

Symbol: DPOLL_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9UGP5 D3DR76 Q5JQP5 Q6NUM2 Q9BTN8 Q9HA10 Q9HB35

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEBI 11 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 12 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 87 PDBsum 87 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 6 Rhea 3 SABIO-RK 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10982892

Title: Two novel human and mouse DNA polymerases of the polX family.

PubMed ID: 10982892

DOI: 10.1093/nar/28.18.3684

PubMed ID: 10887191

Title: Identification and characterization of human DNA polymerase beta 2, a DNA polymerase beta-related enzyme.

PubMed ID: 10887191

DOI: 10.1074/jbc.m004263200

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11457865

Title: Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair.

PubMed ID: 11457865

DOI: 10.1074/jbc.m106336200

PubMed ID: 12809503

Title: Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study.

PubMed ID: 12809503

DOI: 10.1021/bi034198m

PubMed ID: 14627824

Title: Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities.

PubMed ID: 14627824

DOI: 10.1093/nar/gkg896

PubMed ID: 15358682

Title: The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1.

PubMed ID: 15358682

DOI: 10.1096/fj.04-2268fje

PubMed ID: 15537631

Title: DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A.

PubMed ID: 15537631

DOI: 10.1074/jbc.m411650200

PubMed ID: 19806195

Title: Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ.

PubMed ID: 19806195

DOI: 10.1371/journal.pone.0007290

PubMed ID: 20693240

Title: The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway.

PubMed ID: 20693240

DOI: 10.1093/carcin/bgq166

PubMed ID: 30250067

Title: PAXX and its paralogs synergistically direct DNA polymerase lambda activity in DNA repair.

PubMed ID: 30250067

DOI: 10.1038/s41467-018-06127-y

PubMed ID: 12911298

Title: Solution structure of the lyase domain of human DNA polymerase lambda.

PubMed ID: 12911298

DOI: 10.1021/bi034298s

PubMed ID: 14992725

Title: A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology.

PubMed ID: 14992725

DOI: 10.1016/s1097-2765(04)00061-9

PubMed ID: 17475573

Title: Role of the catalytic metal during polymerization by DNA polymerase lambda.

PubMed ID: 17475573

DOI: 10.1016/j.dnarep.2007.03.005

Sequence Information:

  • Length: 575
  • Mass: 63482
  • Checksum: FD9196A1C94923C4
  • Sequence:
    • MDPRGILKAF PKRQKIHADA SSKVLAKIPR REEGEEAEEW LSSLRAHVVR TGIGRARAEL 
FEKQIVQHGG QLCPAQGPGV THIVVDEGMD YERALRLLRL PQLPPGAQLV KSAWLSLCLQ 
ERRLVDVAGF SIFIPSRYLD HPQPSKAEQD ASIPPGTHEA LLQTALSPPP PPTRPVSPPQ 
KAKEAPNTQA QPISDDEASD GEETQVSAAD LEALISGHYP TSLEGDCEPS PAPAVLDKWV 
CAQPSSQKAT NHNLHITEKL EVLAKAYSVQ GDKWRALGYA KAINALKSFH KPVTSYQEAC 
SIPGIGKRMA EKIIEILESG HLRKLDHISE SVPVLELFSN IWGAGTKTAQ MWYQQGFRSL 
EDIRSQASLT TQQAIGLKHY SDFLERMPRE EATEIEQTVQ KAAQAFNSGL LCVACGSYRR 
GKATCGDVDV LITHPDGRSH RGIFSRLLDS LRQEGFLTDD LVSQEENGQQ QKYLGVCRLP 
GPGRRHRRLD IIVVPYSEFA CALLYFTGSA HFNRSMRALA KTKGMSLSEH ALSTAVVRNT 
HGCKVGPGRV LPTPTEKDVF RLLGLPYREP AERDW

Genular Protein ID: 3693916792

Symbol: A8K860_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K860

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 4 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 5 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 2 PROSITE 3 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 Rhea 3 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 4

Sequence Information:

  • Length: 483
  • Mass: 53537
  • Checksum: 83E653AC9586C8D6
  • Sequence:
    • MDPRGILKAF PKRQKIHADA SSKVLAKIPR REEGEEAEEW LSSLRAHVVR TGIGRARAEL 
FEKQIVQHGG QLCPAQGPGV THIVVDEGMD YERALRLLRL PQLPPGAQLV KSAWLSLCLQ 
ERRLVDVAGF SIFIPSRYLD HPQPSKAEQD ASIPPGTHEA LLQTALSPPP PPTRPVSPPQ 
KAKEAPNTQA QPISDDEASD GEETQEACSI PGIGKRMAEK IIEILESGHL RKLDHISESV 
PVLELFSNIW GAGTKTAQMW YQQGFRSLED IRSQASLTTQ QAIGLKHYSD FLERMPREEA 
TEIEQTVQKA AQAFNSGLLC VACGSYRRGK ATCGDVDVLI THPDGRSHRG IFSRLLDSLR 
QEGFLTDDLV SQEENGQQQK YLGVCRLPGP GRRHRRLDII VVPYSEFACA LLYFTGSAHF 
NRSMRALAKT KGMSLSEHAL STAVVRNTHG CKVGPGRVLP TPTEKDVFRL LGLPYREPAE 
RDW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.