Details for: GSN

Gene ID: 2934

Symbol: GSN

Ensembl ID: ENSG00000148180

Description: gelsolin

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 7.17
    Marker Score: 4,721
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 4.29
    Marker Score: 5,345
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 4.02
    Marker Score: 3,431
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 4.01
    Marker Score: 13,142
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.53
    Marker Score: 120,131
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 3.52
    Marker Score: 3,354
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 3.4
    Marker Score: 6,201
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 3.34
    Marker Score: 21,318
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 3.23
    Marker Score: 8,213
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 3.16
    Marker Score: 735
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 3.13
    Marker Score: 8,195
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 3.12
    Marker Score: 4,067
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 3.1
    Marker Score: 4,509
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 3.05
    Marker Score: 1,313
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 3.05
    Marker Score: 2,923
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 3.04
    Marker Score: 6,065
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 3.03
    Marker Score: 7,257
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 3.03
    Marker Score: 5,686
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 3.01
    Marker Score: 2,592
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 3
    Marker Score: 1,251
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.96
    Marker Score: 3,387
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.94
    Marker Score: 4,981
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 2.92
    Marker Score: 2,079
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.9
    Marker Score: 4,203
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.84
    Marker Score: 12,231
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.83
    Marker Score: 1,536
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.78
    Marker Score: 6,114
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 2.78
    Marker Score: 2,687
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2.73
    Marker Score: 4,973
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.73
    Marker Score: 3,669
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.69
    Marker Score: 20,056
  • Cell Name: tracheobronchial goblet cell (CL0019003)
    Fold Change: 2.63
    Marker Score: 721
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 2.61
    Marker Score: 2,592
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 2.58
    Marker Score: 22,387
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.53
    Marker Score: 1,416
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 2.53
    Marker Score: 19,768
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.53
    Marker Score: 1,442
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 2.52
    Marker Score: 21,738
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.52
    Marker Score: 4,469
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 2.5
    Marker Score: 1,234
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 2.49
    Marker Score: 1,641
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 2.48
    Marker Score: 644
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 2.47
    Marker Score: 901
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 2.46
    Marker Score: 2,650
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.45
    Marker Score: 1,636
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.43
    Marker Score: 2,561
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 2.43
    Marker Score: 2,288
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 2.41
    Marker Score: 764
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 2.41
    Marker Score: 554
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.37
    Marker Score: 969
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.37
    Marker Score: 50,628
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 2.34
    Marker Score: 2,824
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 2.32
    Marker Score: 6,009
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.32
    Marker Score: 59,332
  • Cell Name: pericyte (CL0000669)
    Fold Change: 2.3
    Marker Score: 1,345
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 2.28
    Marker Score: 567
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 2.27
    Marker Score: 941
  • Cell Name: club cell (CL0000158)
    Fold Change: 2.27
    Marker Score: 2,648
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 2.26
    Marker Score: 567
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.24
    Marker Score: 2,009
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.24
    Marker Score: 25,225
  • Cell Name: basal cell (CL0000646)
    Fold Change: 2.23
    Marker Score: 2,883
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 2.23
    Marker Score: 643
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.22
    Marker Score: 1,103
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.22
    Marker Score: 8,549
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.21
    Marker Score: 697
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.2
    Marker Score: 2,533
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.19
    Marker Score: 793
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 2.19
    Marker Score: 620
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 2.19
    Marker Score: 619
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.16
    Marker Score: 839
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.13
    Marker Score: 4,098
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 2.11
    Marker Score: 1,334
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 2.11
    Marker Score: 4,014
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 2.1
    Marker Score: 1,900
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 2.1
    Marker Score: 2,887
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 2.09
    Marker Score: 654
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 2.09
    Marker Score: 612
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 2.08
    Marker Score: 1,012
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 2.08
    Marker Score: 1,278
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 2.07
    Marker Score: 440
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 2.06
    Marker Score: 2,540
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.05
    Marker Score: 523
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 2.01
    Marker Score: 11,932
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.96
    Marker Score: 1,143
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.95
    Marker Score: 2,159
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.93
    Marker Score: 1,267
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 1.92
    Marker Score: 682
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.92
    Marker Score: 66,445
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.91
    Marker Score: 2,241
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 1.91
    Marker Score: 461
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.91
    Marker Score: 558
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.91
    Marker Score: 10,028
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 1.91
    Marker Score: 797
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 1.89
    Marker Score: 640
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.88
    Marker Score: 4,595
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.87
    Marker Score: 18,982
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.87
    Marker Score: 806
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.86
    Marker Score: 459
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.86
    Marker Score: 868

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** Gelsolin is a 20-kDa protein that belongs to the actin-binding protein family. It is composed of three domains: a proline-rich domain, a calcium-binding domain, and a globular domain. The protein's ability to bind and hydrolyze actin filaments is mediated by its globular domain, which contains two actin-binding sites. Gelsolin's actin-binding properties allow it to regulate actin filament organization, polymerization, and depolymerization, influencing various cellular processes. Gelsolin's unique characteristics include: 1. **Actin-binding properties**: Gelsolin's ability to bind and hydrolyze actin filaments is mediated by its globular domain. 2. **Calcium-dependent**: Gelsolin's activity is regulated by calcium ions, which bind to its calcium-binding domain. 3. **Proline-rich domain**: Gelsolin's proline-rich domain is involved in protein-protein interactions and regulates its activity. 4. **Multifunctional**: Gelsolin's unique properties allow it to regulate various cellular processes, including cell migration, division, and apoptosis. **Pathways and Functions** Gelsolin's involvement in various cellular processes is mediated through its regulation of the actin cytoskeleton. Some of the key pathways and functions include: 1. **Actin filament organization**: Gelsolin regulates actin filament organization, influencing cell shape, migration, and division. 2. **Cell migration**: Gelsolin's regulation of actin filament organization is essential for cell migration, a critical process in development, tissue repair, and disease. 3. **Apoptosis**: Gelsolin's ability to regulate actin filament organization and polymerization is also involved in apoptosis, a critical process in cellular development and tissue homeostasis. 4. **Cytoskeleton regulation**: Gelsolin's regulation of actin filament organization and polymerization is essential for maintaining cytoskeleton homeostasis, influencing cellular behavior and function. 5. **Cell signaling**: Gelsolin's regulation of actin filament organization is also involved in cell signaling, influencing the transmission of signals between cells. **Clinical Significance** Dysregulation of Gelsolin's activity has been implicated in various diseases, including: 1. **Muscular dystrophy**: Gelsolin's dysregulation has been linked to muscular dystrophy, a group of genetic disorders characterized by progressive muscle weakness and degeneration. 2. **Cancer**: Gelsolin's dysregulation has been implicated in cancer, influencing tumor cell migration, invasion, and metastasis. 3. **Neurological disorders**: Gelsolin's dysregulation has been linked to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 4. **Cardiovascular disease**: Gelsolin's dysregulation has been implicated in cardiovascular disease, influencing cardiac muscle contraction and relaxation. In conclusion, Gelsolin is a multifunctional protein that plays a critical role in regulating the actin cytoskeleton, influencing various cellular processes, including cell migration, division, and apoptosis. Its dysregulation has been implicated in various diseases, highlighting the importance of maintaining its activity and function in maintaining cellular homeostasis and preventing disease.

Genular Protein ID: 532905611

Symbol: GELS_HUMAN

Name: Gelsolin

UniProtKB Accession Codes:

P06396 A2A418 A8MUD1 A8MYN7 B7Z373 B7Z5V1 F5H1A8 Q5T0I2 Q8WVV7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 6 CORUM 1 CPTAC 2 CPTC 1 CTD 1 ChEBI 29 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 EMBL 13 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 54 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 82 PDBsum 58 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 4 RefSeq 25 SABIO-RK 1 SAM 1 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3020431

Title: Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.

PubMed ID: 3020431

DOI: 10.1038/323455a0

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 6092370

Title: Human plasma gelsolin binds to fibronectin.

PubMed ID: 6092370

DOI: 10.1016/s0021-9258(18)90687-3

PubMed ID: 2157434

Title: Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein.

PubMed ID: 2157434

DOI: 10.1016/0006-291x(90)90612-q

PubMed ID: 2153578

Title: Finnish hereditary amyloidosis. Amino acid sequence homology between the amyloid fibril protein and human plasma gelsoline.

PubMed ID: 2153578

DOI: 10.1016/0014-5793(90)80072-q

PubMed ID: 8703941

Title: The plasma and cytoplasmic forms of human gelsolin differ in disulfide structure.

PubMed ID: 8703941

DOI: 10.1021/bi960920n

PubMed ID: 9003812

Title: Functional consequences of disulfide bond formation in gelsolin.

PubMed ID: 9003812

DOI: 10.1016/s0014-5793(96)01439-1

PubMed ID: 10210201

Title: Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach.

PubMed ID: 10210201

DOI: 10.1110/ps.8.1.234

PubMed ID: 20393563

Title: Functional genomic screen for modulators of ciliogenesis and cilium length.

PubMed ID: 20393563

DOI: 10.1038/nature08895

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 8395021

Title: Structure of gelsolin segment 1-actin complex and the mechanism of filament severing.

PubMed ID: 8395021

DOI: 10.1038/364685a0

PubMed ID: 8599675

Title: Spectroscopic studies of a phosphoinositide-binding peptide from gelsolin: behavior in solutions of mixed solvent and anionic micelles.

PubMed ID: 8599675

DOI: 10.1016/s0006-3495(95)80140-2

PubMed ID: 12460571

Title: The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex.

PubMed ID: 12460571

DOI: 10.1016/s0022-2836(02)01131-2

PubMed ID: 16466744

Title: Calcium ion exchange in crystalline gelsolin.

PubMed ID: 16466744

DOI: 10.1016/j.jmb.2006.01.026

PubMed ID: 19666512

Title: Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.

PubMed ID: 19666512

DOI: 10.1073/pnas.0812374106

PubMed ID: 23009842

Title: Structural states and dynamics of the D-loop in actin.

PubMed ID: 23009842

DOI: 10.1016/j.bpj.2012.07.030

PubMed ID: 2176481

Title: Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type.

PubMed ID: 2176481

DOI: 10.1042/bj2720827

PubMed ID: 1338910

Title: Gelsolin-derived familial amyloidosis caused by asparagine or tyrosine substitution for aspartic acid at residue 187.

PubMed ID: 1338910

DOI: 10.1038/ng1092-157

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 782
  • Mass: 85698
  • Checksum: 8CEBC52257A160F7
  • Sequence:
    • MAPHRPAPAL LCALSLALCA LSLPVRAATA SRGASQAGAP QGRVPEARPN SMVVEHPEFL 
KAGKEPGLQI WRVEKFDLVP VPTNLYGDFF TGDAYVILKT VQLRNGNLQY DLHYWLGNEC 
SQDESGAAAI FTVQLDDYLN GRAVQHREVQ GFESATFLGY FKSGLKYKKG GVASGFKHVV 
PNEVVVQRLF QVKGRRVVRA TEVPVSWESF NNGDCFILDL GNNIHQWCGS NSNRYERLKA 
TQVSKGIRDN ERSGRARVHV SEEGTEPEAM LQVLGPKPAL PAGTEDTAKE DAANRKLAKL 
YKVSNGAGTM SVSLVADENP FAQGALKSED CFILDHGKDG KIFVWKGKQA NTEERKAALK 
TASDFITKMD YPKQTQVSVL PEGGETPLFK QFFKNWRDPD QTDGLGLSYL SSHIANVERV 
PFDAATLHTS TAMAAQHGMD DDGTGQKQIW RIEGSNKVPV DPATYGQFYG GDSYIILYNY 
RHGGRQGQII YNWQGAQSTQ DEVAASAILT AQLDEELGGT PVQSRVVQGK EPAHLMSLFG 
GKPMIIYKGG TSREGGQTAP ASTRLFQVRA NSAGATRAVE VLPKAGALNS NDAFVLKTPS 
AAYLWVGTGA SEAEKTGAQE LLRVLRAQPV QVAEGSEPDG FWEALGGKAA YRTSPRLKDK 
KMDAHPPRLF ACSNKIGRFV IEEVPGELMQ EDLATDDVML LDTWDQVFVW VGKDSQEEEK 
TEALTSAKRY IETDPANRDR RTPITVVKQG FEPPSFVGWF LGWDDDYWSV DPLDRAMAEL 
AA

Genular Protein ID: 1785533618

Symbol: A0A0A0MS51_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MS51

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 6 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRIDE 1 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 748
  • Mass: 82526
  • Checksum: 01F62E541304E853
  • Sequence:
    • MAEEEALRGN SDPWPNSMVV EHPEFLKAGK EPGLQIWRVE KFDLVPVPTN LYGDFFTGDA 
YVILKTVQLR NGNLQYDLHY WLGNECSQDE SGAAAIFTVQ LDDYLNGRAV QHREVQGFES 
ATFLGYFKSG LKYKKGGVAS GFKHVVPNEV VVQRLFQVKG RRVVRATEVP VSWESFNNGD 
CFILDLGNNI HQWCGSNSNR YERLKATQVS KGIRDNERSG RARVHVSEEG TEPEAMLQVL 
GPKPALPAGT EDTAKEDAAN RKLAKLYKVS NGAGTMSVSL VADENPFAQG ALKSEDCFIL 
DHGKDGKIFV WKGKQANTEE RKAALKTASD FITKMDYPKQ TQVSVLPEGG ETPLFKQFFK 
NWRDPDQTDG LGLSYLSSHI ANVERVPFDA ATLHTSTAMA AQHGMDDDGT GQKQIWRIEG 
SNKVPVDPAT YGQFYGGDSY IILYNYRHGG RQGQIIYNWQ GAQSTQDEVA ASAILTAQLD 
EELGGTPVQS RVVQGKEPAH LMSLFGGKPM IIYKGGTSRE GGQTAPASTR LFQVRANSAG 
ATRAVEVLPK AGALNSNDAF VLKTPSAAYL WVGTGASEAE KTGAQELLRV LRAQPVQVAE 
GSEPDGFWEA LGGKAAYRTS PRLKDKKMDA HPPRLFACSN KIGRFVIEEV PGELMQEDLA 
TDDVMLLDTW DQVFVWVGKD SQEEEKTEAL TSAKRYIETD PANRDRRTPI TVVKQGFEPP 
SFVGWFLGWD DDYWSVDPLD RAMAELAA

Genular Protein ID: 1808108869

Symbol: A0A0A0MT01_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MT01

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 6 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRIDE 1 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 767
  • Mass: 84745
  • Checksum: 0AFF281D6076CC6F
  • Sequence:
    • MNTGLTRLLW PSWLPDGDMS HPQPELFLFP KAQPNSMVVE HPEFLKAGKE PGLQIWRVEK 
FDLVPVPTNL YGDFFTGDAY VILKTVQLRN GNLQYDLHYW LGNECSQDES GAAAIFTVQL 
DDYLNGRAVQ HREVQGFESA TFLGYFKSGL KYKKGGVASG FKHVVPNEVV VQRLFQVKGR 
RVVRATEVPV SWESFNNGDC FILDLGNNIH QWCGSNSNRY ERLKATQVSK GIRDNERSGR 
ARVHVSEEGT EPEAMLQVLG PKPALPAGTE DTAKEDAANR KLAKLYKVSN GAGTMSVSLV 
ADENPFAQGA LKSEDCFILD HGKDGKIFVW KGKQANTEER KAALKTASDF ITKMDYPKQT 
QVSVLPEGGE TPLFKQFFKN WRDPDQTDGL GLSYLSSHIA NVERVPFDAA TLHTSTAMAA 
QHGMDDDGTG QKQIWRIEGS NKVPVDPATY GQFYGGDSYI ILYNYRHGGR QGQIIYNWQG 
AQSTQDEVAA SAILTAQLDE ELGGTPVQSR VVQGKEPAHL MSLFGGKPMI IYKGGTSREG 
GQTAPASTRL FQVRANSAGA TRAVEVLPKA GALNSNDAFV LKTPSAAYLW VGTGASEAEK 
TGAQELLRVL RAQPVQVAEG SEPDGFWEAL GGKAAYRTSP RLKDKKMDAH PPRLFACSNK 
IGRFVIEEVP GELMQEDLAT DDVMLLDTWD QVFVWVGKDS QEEEKTEALT SAKRYIETDP 
ANRDRRTPIT VVKQGFEPPS FVGWFLGWDD DYWSVDPLDR AMAELAA

Genular Protein ID: 3004336481

Symbol: B7Z4U6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z4U6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 5 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 689
  • Mass: 75752
  • Checksum: 22FEF22DD9D9B51D
  • Sequence:
    • MAEEEALRGN SDPWPNSMVV EHPEFLKAGK EPGLQIWRVE KFDLVPVPTN LYGDFFTGDA 
YVILKTVQLR NGNLQYDLHY WLGNECSQDE SGAAAIFTVQ LDDYLNGRAV QHREVQGFES 
ATFLGYFKSG LKYKKGGVAS GFKHVVPNEV VVQRLFQVKG RRVVRATEVP VSWESFNNGD 
CFILDLGNNI HQWCGSNSNR YERLKATQVS KGIRDNERSG RARVHVSEEG TEPEAMLQVL 
GPKPALPAGT EDTAKEDAAN HKLAKLYKVS NGAGTMSVSL VADENPFAQG ALKSEDCFIL 
DHGKDGKIFV WKGKQANTEE RKAALKTASD FITKMDYPKQ TQVSVLPEGG ETPLFKQFFK 
NWRDPDQTDG LGLSYLSSHI ANVERVPFDA ATLHTSTAMA AQHGMDDDGT GQKQIWRIEG 
SNKVPVDPAT YGQFYGGDSY IILYNYRHGG RQGQIIYNWQ GAQSTQDEVA ASAILTAQLD 
EELGGTPVQS RVVQGKEPAH LMSLFGGKPM IIYKGGTSRE GGQTAPASTR LFQVRANSAG 
ATRAVEVLPK AGALNSNDAF VLKTPSAAYL WVGTGASEAE KTGAQELLRV LRAQPVQVAE 
GSEPDGFWEA LGGKAAYRTS PRLKDKKMDA HPPRLFACSN KIGRFVIEEV PGELMQEDLA 
TDDVMLLDTW DQVFVWVGKD SQEEEKTEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.