Details for: GTF2I

Gene ID: 2969

Symbol: GTF2I

Ensembl ID: ENSG00000263001

Description: general transcription factor IIi

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 6.93
    Marker Score: 92232
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 6.93
    Marker Score: 19558
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 4.64
    Marker Score: 2254.5
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 4.46
    Marker Score: 4725.5
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 3.85
    Marker Score: 7970
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 3.79
    Marker Score: 4090.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 3.73
    Marker Score: 7176.5
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 3.55
    Marker Score: 21039
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.41
    Marker Score: 3857.5
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.2
    Marker Score: 14805
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 3.05
    Marker Score: 7682
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 3
    Marker Score: 4977
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.97
    Marker Score: 3993
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 2.95
    Marker Score: 4178
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.9
    Marker Score: 2570
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.81
    Marker Score: 3396
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.8
    Marker Score: 59813
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.7
    Marker Score: 1877
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.69
    Marker Score: 9581
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.67
    Marker Score: 39904
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.64
    Marker Score: 20232
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 2.64
    Marker Score: 1404
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.63
    Marker Score: 52232
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.61
    Marker Score: 58337
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 2.59
    Marker Score: 2315
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.59
    Marker Score: 98319
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.59
    Marker Score: 22696
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.5
    Marker Score: 3109.5
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.43
    Marker Score: 2792
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 2.42
    Marker Score: 2595
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.42
    Marker Score: 83798
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.41
    Marker Score: 6039
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.4
    Marker Score: 9949
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.36
    Marker Score: 1333
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.34
    Marker Score: 1806
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.34
    Marker Score: 1306
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 2.33
    Marker Score: 31266
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.32
    Marker Score: 85746.5
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.29
    Marker Score: 17015
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 2.28
    Marker Score: 864
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.27
    Marker Score: 2299
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 2.26
    Marker Score: 4777.5
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.26
    Marker Score: 1350
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.26
    Marker Score: 1485
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 2.25
    Marker Score: 19559
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 2.25
    Marker Score: 648
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 2.24
    Marker Score: 820.5
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.24
    Marker Score: 7948
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.22
    Marker Score: 8592
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.21
    Marker Score: 896
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.21
    Marker Score: 29106
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.2
    Marker Score: 4840
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.2
    Marker Score: 560.5
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.18
    Marker Score: 6226
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 2.18
    Marker Score: 11460
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 2.18
    Marker Score: 8063
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.17
    Marker Score: 9091.5
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.16
    Marker Score: 4397
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.15
    Marker Score: 782
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.15
    Marker Score: 2046
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.13
    Marker Score: 4452
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.13
    Marker Score: 1337
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.13
    Marker Score: 1119.5
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.13
    Marker Score: 2271
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.12
    Marker Score: 21511.5
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.12
    Marker Score: 5763.5
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.11
    Marker Score: 1236
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 2.11
    Marker Score: 677
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.1
    Marker Score: 3528
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.1
    Marker Score: 8707.5
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.08
    Marker Score: 20890
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.08
    Marker Score: 13501
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.08
    Marker Score: 19523
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 2.06
    Marker Score: 1378
  • Cell Name: Unknown (CL0002371)
    Fold Change: 2.05
    Marker Score: 2181
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.05
    Marker Score: 1193
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.03
    Marker Score: 1005
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 2.03
    Marker Score: 683
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.03
    Marker Score: 124853
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 2.02
    Marker Score: 754
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2
    Marker Score: 5347
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.99
    Marker Score: 1868.5
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.97
    Marker Score: 711.5
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.95
    Marker Score: 1838
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.93
    Marker Score: 4541.5
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.93
    Marker Score: 1286
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.91
    Marker Score: 2055
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 1.9
    Marker Score: 1129
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.89
    Marker Score: 894
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.89
    Marker Score: 1102
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 1.87
    Marker Score: 3563
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.87
    Marker Score: 1978
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.87
    Marker Score: 21012
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.86
    Marker Score: 972
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.86
    Marker Score: 17665
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 1.86
    Marker Score: 1127
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.84
    Marker Score: 1256
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.84
    Marker Score: 1015
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.84
    Marker Score: 2031
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 1.83
    Marker Score: 3145

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Other Information

## Summary GTF2I is a general transcription factor II that plays a crucial role in various cellular processes. It is highly expressed in the cardiovascular, respiratory, and renal systems and is involved in regulating cell proliferation, differentiation, and survival. ## Key characteristics * GTF2I is a protein with a molecular weight of approximately 130 kDa. * It is a DNA-binding transcription factor that belongs to the GTF family of transcription factors. * GTF2I is a key regulator of gene expression in various cell types. * It is involved in the regulation of cardiac development, angiogenesis, and inflammation. * It is also involved in the regulation of cell proliferation, differentiation, and survival. ## Pathways and functions * GTF2I binds to DNA sequences known as GTF-binding elements (GBEs) in the promoter regions of target genes. * Once bound to DNA, GTF2I recruits RNA polymerase II to the promoter region of the target gene, where it initiates transcription. * GTF2I also interacts with other transcription factors and modulates their activity. * It plays a critical role in regulating the expression of genes involved in cardiac development, angiogenesis, and inflammation. ## Clinical significance * Mutations in GTF2I have been linked to various human diseases, including cardiovascular disease, cancer, and pulmonary disease. * GTF2I is a potential therapeutic target for diseases characterized by abnormal cell growth and survival. * Inhibition of GTF2I has been shown to inhibit cell growth and migration, suggesting that it may be a potential therapeutic agent for cancer. ## Additional information * GTF2I is a highly conserved protein with similar sequences in other species. * It is a well-studied protein that has been extensively characterized in both mammals and humans. * GTF2I is a transcription factor that is essential for the development and maintenance of complex tissues such as the heart, lungs, and kidneys.

Genular Protein ID: 2191030026

Symbol: GTF2I_HUMAN

Name: General transcription factor II-I

UniProtKB Accession Codes:

P78347 O14743 O15359 O43546 O43588 O43589 Q75M85 Q75M86 Q75M87 Q75M88 Q86U51 Q9BSZ4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CORUM 1 CPTAC 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 18 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 4 PIR 2 PIRSF 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 6 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9384587

Title: Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1.

PubMed ID: 9384587

DOI: 10.1093/emboj/16.23.7091

PubMed ID: 9334314

Title: A multifunctional DNA-binding protein that promotes the formation of serum response factor/homeodomain complexes: identity to TFII-I.

PubMed ID: 9334314

DOI: 10.1101/gad.11.19.2482

PubMed ID: 9012831

Title: BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement.

PubMed ID: 9012831

DOI: 10.1073/pnas.94.2.604

PubMed ID: 9466987

Title: A duplicated gene in the breakpoint regions of the 7q11.23 Williams-Beuren syndrome deletion encodes the initiator binding protein TFII-I and BAP-135, a phosphorylation target of BTK.

PubMed ID: 9466987

DOI: 10.1093/hmg/7.3.325

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10373551

Title: Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase.

PubMed ID: 10373551

DOI: 10.1128/mcb.19.7.5014

PubMed ID: 11373296

Title: Identification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-I.

PubMed ID: 11373296

DOI: 10.1074/jbc.m103692200

PubMed ID: 12082086

Title: cGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-I.

PubMed ID: 12082086

DOI: 10.1074/jbc.m112332200

PubMed ID: 15561718

Title: Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.

PubMed ID: 15561718

DOI: 10.1074/jbc.m411718200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16738337

Title: Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I.

PubMed ID: 16738337

DOI: 10.1128/mcb.02009-05

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 31900622

Title: GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors.

PubMed ID: 31900622

DOI: 10.1007/s00018-019-03440-7

Sequence Information:

  • Length: 998
  • Mass: 112416
  • Checksum: 4CFA2C19002869B9
  • Sequence:
    • MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 
SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 
EESEDPDYYQ YNIQAGPSET DDVDEKQPLS KPLQGSHHSS EGNEGTEMEV PAEDSTQHVP 
SETSEDPEVE VTIEDDDYSP PSKRPKANEL PQPPVPEPAN AGKRKVREFN FEKWNARITD 
LRKQVEELFE RKYAQAIKAK GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE 
RILLAKERIR FVIKKHELLN STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE 
ALGSTEAKAV PYQKFEAHPN DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR 
PELLTHSTTE VTQPRTNTPV KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF 
ESNPEFLYVE GLPEGIPFRS PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK 
INTKALQSPK RPRSPGSNSK VPEIEVTVEG PNNNNPQTSA VRTPTQTNGS NVPFKPRGRE 
FSFEAWNAKI TDLKQKVENL FNEKCGEALG LKQAVKVPFA LFESFPEDFY VEGLPEGVPF 
RRPSTFGIPR LEKILRNKAK IKFIIKKPEM FETAIKESTS SKSPPRKINS SPNVNTTASG 
VEDLNIIQVT IPDDDNERLS KVEKARQLRE QVNDLFSRKF GEAIGMGFPV KVPYRKITIN 
PGCVVVDGMP PGVSFKAPSY LEISSMRRIL DSAEFIKFTV IRPFPGLVIN NQLVDQSESE 
GPVIQESAEP SQLEVPATEE IKETDGSSQI KQEPDPTW

Genular Protein ID: 1442034434

Symbol: X5D2J9_HUMAN

Name: N/A

UniProtKB Accession Codes:

X5D2J9

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 2 Gene3D 1 GenomeRNAi 1 HOGENOM 1 InterPro 3 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PROSITE 1 Pfam 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 24722188

Title: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

PubMed ID: 24722188

Sequence Information:

  • Length: 957
  • Mass: 107970
  • Checksum: E091B620FF633AC8
  • Sequence:
    • MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 
SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 
EESEDPDYYQ YNIQGSHHSS EGNEGTEMEV PAEDDDYSPP SKRPKANELP QPPVPEPANA 
GKRKVREFNF EKWNARITDL RKQVEELFER KYAQAIKAKG PVTIPYPLFQ SHVEDLYVEG 
LPEGIPFRRP STYGIPRLER ILLAKERIRF VIKKHELLNS TREDLQLDKP ASGVKEEWYA 
RITKLRKMVD QLFCKKFAEA LGSTEAKAVP YQKFEAHPND LYVEGLPENI PFRSPSWYGI 
PRLEKIIQVG NRIKFVIKRP ELLTHSTTEV TQPRTNTPVK EDWNVRITKL RKQVEEIFNL 
KFAQALGLTE AVKVPYPVFE SNPEFLYVEG LPEGIPFRSP TWFGIPRLER IVRGSNKIKF 
VVKKPELVIS YLPPGMASKI NTKALQSPKR PRSPGSNSKV PEIEVTVEGP NNNNPQTSAV 
RTPTQTNGSN VPFKPRGREF SFEAWNAKIT DLKQKVENLF NEKCGEALGL KQAVKVPFAL 
FESFPEDFYV EGLPEGVPFR RPSTFGIPRL EKILRNKAKI KFIIKKPEMF ETAIKESTSS 
KSPPRKINSS PNVNTTASGV EDLNIIQVTI PDDDNERLSK VEKARQLREQ VNDLFSRKFG 
EAIGMGFPVK VPYRKITINP GCVVVDGMPP GVSFKAPSYL EISSMRRILD SAEFIKFTVI 
RPFPGLVINN QLVDQSESEG PVIQESAEPS QLEVPATEEI KETDGSSQIK QEPDPTW

Genular Protein ID: 3067323723

Symbol: X5D939_HUMAN

Name: N/A

UniProtKB Accession Codes:

X5D939

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 3 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PROSITE 1 Pfam 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 24722188

Title: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

PubMed ID: 24722188

Sequence Information:

  • Length: 977
  • Mass: 110106
  • Checksum: 418D59EC623E6141
  • Sequence:
    • MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 
SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 
EESEDPDYYQ YNIQAGPSET DDVDEKQPLS KPLQGSHHSS EGNEGTEMEV PAEDDDYSPP 
SKRPKANELP QPPVPEPANA GKRKVREFNF EKWNARITDL RKQVEELFER KYAQAIKAKG 
PVTIPYPLFQ SHVEDLYVEG LPEGIPFRRP STYGIPRLER ILLAKERIRF VIKKHELLNS 
TREDLQLDKP ASGVKEEWYA RITKLRKMVD QLFCKKFAEA LGSTEAKAVP YQKFEAHPND 
LYVEGLPENI PFRSPSWYGI PRLEKIIQVG NRIKFVIKRP ELLTHSTTEV TQPRTNTPVK 
EDWNVRITKL RKQVEEIFNL KFAQALGLTE AVKVPYPVFE SNPEFLYVEG LPEGIPFRSP 
TWFGIPRLER IVRGSNKIKF VVKKPELVIS YLPPGMASKI NTKALQSPKR PRSPGSNSKV 
PEIEVTVEGP NNNNPQTSAV RTPTQTNGSN VPFKPRGREF SFEAWNAKIT DLKQKVENLF 
NEKCGEALGL KQAVKVPFAL FESFPEDFYV EGLPEGVPFR RPSTFGIPRL EKILRNKAKI 
KFIIKKPEMF ETAIKESTSS KSPPRKINSS PNVNTTASGV EDLNIIQVTI PDDDNERLSK 
VEKARQLREQ VNDLFSRKFG EAIGMGFPVK VPYRKITINP GCVVVDGMPP GVSFKAPSYL 
EISSMRRILD SAEFIKFTVI RPFPGLVINN QLVDQSESEG PVIQESAEPS QLEVPATEEI 
KETDGSSQIK QEPDPTW

Genular Protein ID: 2203699117

Symbol: Q499G6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q499G6

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 3 KEGG 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 1 Pfam 1 PharmGKB 1 RefSeq 5 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 976
  • Mass: 110080
  • Checksum: C25BEE75CDED523E
  • Sequence:
    • MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 
SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 
EESEDPDYYQ YNIQGPSETD DVDEKQPLSK PLQGSHHSSE GNEGTEMEVP AEDDDYSPPS 
KRPKANELPQ PPVPEPANAG KRKVREFNFE KWNARITDLR KQVEELFERK YAQAIKAKGP 
VTIPYPLFQS HVEDLYVEGL PEGIPFRRPS TYGIPRLERI LLAKERIRFV IKKHELLNST 
REDLQLDKPA SGVKEEWYAR ITKLRKMVDQ LFCKKFAEAL GSTEAKAVPY QKFEAHPNDL 
YVEGLPENIP FRSPSWYGIP RLEKIIQVGN RIKFVIKRPE LLTHSTTEVT QPRTNTPVKE 
DWNVRITKLR KQVEEIFNLK FAQALGLTEA VKVPYPVFES NPEFLYVEGL PEGIPFRSPT 
WFGIPRLERI VRGSNKIKFV VKKPELVISY LPPGMASKIN TKALQSPKRP RSPGSNSKVP 
EIEVTVEGPN NNNPQTSAVR TPTQTNGSNV PFKPRGREFS FEAWNAKITD LKQKVENLFN 
EKCGEALGLK QAVKVPFALF ESFPEDFYVE GLPEGVPFRR PSTFGIPRLE KILRNKAKIK 
FIIKKPEMFE TAIKESTSSK SPPRKINSSP NVNTTASGVE DLNIIQVTIP DDDNERLSKV 
EKARQLREQV NDLFSRKFGE AIGMGFPVKV PYRKITINRG CVVVDGMPPG VSFKAPSYLE 
ISSMRRILDS AEFIKFTVIR PFPGLVVNNQ LVDQSESEGP VIQESAEPSQ LEVPATEEIK 
ETDGSSQIKQ EPDPTW

Genular Protein ID: 2415940495

Symbol: X5DNP5_HUMAN

Name: N/A

UniProtKB Accession Codes:

X5DNP5

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 3 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PROSITE 1 Pfam 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 24722188

Title: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

PubMed ID: 24722188

Sequence Information:

  • Length: 978
  • Mass: 110280
  • Checksum: 1F006D480F0BE702
  • Sequence:
    • MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 
SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 
EESEDPDYYQ YNIQGSHHSS EGNEGTEMEV PAEDSTQHVP SETSEDPEVE VTIEDDDYSP 
PSKRPKANEL PQPPVPEPAN AGKRKVREFN FEKWNARITD LRKQVEELFE RKYAQAIKAK 
GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE RILLAKERIR FVIKKHELLN 
STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE ALGSTEAKAV PYQKFEAHPN 
DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR PELLTHSTTE VTQPRTNTPV 
KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF ESNPEFLYVE GLPEGIPFRS 
PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK INTKALQSPK RPRSPGSNSK 
VPEIEVTVEG PNNNNPQTSA VRTPTQTNGS NVPFKPRGRE FSFEAWNAKI TDLKQKVENL 
FNEKCGEALG LKQAVKVPFA LFESFPEDFY VEGLPEGVPF RRPSTFGIPR LEKILRNKAK 
IKFIIKKPEM FETAIKESTS SKSPPRKINS SPNVNTTASG VEDLNIIQVT IPDDDNERLS 
KVEKARQLRE QVNDLFSRKF GEAIGMGFPV KVPYRKITIN PGCVVVDGMP PGVSFKAPSY 
LEISSMRRIL DSAEFIKFTV IRPFPGLVIN NQLVDQSESE GPVIQESAEP SQLEVPATEE 
IKETDGSSQI KQEPDPTW

Genular Protein ID: 804126317

Symbol: A8K9W7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K9W7

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 6 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 978
  • Mass: 110208
  • Checksum: 1FAA4EDECD7724E8
  • Sequence:
    • MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 
SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 
EESEDPDYYQ YNIQGSHHSS EGNEGTEMEV PAEDSTQHVP SETSEDPEVE VTIEDDDYSP 
PSKRPKANEL PQPPVPEPAN AGKRKVREFN FEKWNARITD LRKQVEELFE RKYAQAIKAK 
GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE RILLAKERIR FVIKKHELLN 
STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE ALGSTEAKAV PYQKFEAHPN 
DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR PELLTHSTTE VTQPRTNTPV 
KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF ESNPEFLYVG GLPEGIPFRS 
PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK INTKALQSPK RPRSPGSNSK 
VPEIEVTVEG PNNNNPQTSA VRTPTQTNGS NVPFKPRGRE FSFEAWNAKI TDLKQKVENL 
FNEKCGEALG LKQAVKVPFA LFESFPEDFY VEGLPEGVPF RRPSTFGIPR LEKILRNKAK 
IKFIIKKPEM FETAIKESTS SKSPPRKINS SPNVNTTASG VEDLNIIQVT IPDDDNERLS 
KVEKARQLRE QVNDLFSRKF GEAIGMGFPV KVPYRKITIN PGCVVVDGMP PGVSFKAPSY 
LEISSMRRIL DSAEFIKFTV IRPFPGLVIN NQLVDQSESE GPVIQESAEP SQLEVPATEE 
IKETDGSSQI KQEPDPTW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.