Details for: SENP1

Gene ID: 29843

Symbol: SENP1

Ensembl ID: ENSG00000079387

Description: SUMO specific peptidase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 117.7150
    Cell Significance Index: -18.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 72.7399
    Cell Significance Index: -18.4500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 41.0275
    Cell Significance Index: -19.3700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 39.7778
    Cell Significance Index: -16.1600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 16.9784
    Cell Significance Index: -16.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.3128
    Cell Significance Index: -18.8800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.0142
    Cell Significance Index: -18.7900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.9618
    Cell Significance Index: -15.2400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.8403
    Cell Significance Index: -19.1000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.5045
    Cell Significance Index: -7.6700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.4343
    Cell Significance Index: 141.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.0686
    Cell Significance Index: 14.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9157
    Cell Significance Index: 181.7300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7690
    Cell Significance Index: 125.0700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7561
    Cell Significance Index: 82.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6627
    Cell Significance Index: 132.9400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5897
    Cell Significance Index: 35.4000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5479
    Cell Significance Index: 494.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4894
    Cell Significance Index: 27.4600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4470
    Cell Significance Index: 52.0900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4006
    Cell Significance Index: 277.1000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3960
    Cell Significance Index: 10.1800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3498
    Cell Significance Index: 125.4600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3468
    Cell Significance Index: 23.9900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3351
    Cell Significance Index: 9.3700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3135
    Cell Significance Index: 24.0600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2954
    Cell Significance Index: 18.6200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2583
    Cell Significance Index: 30.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2147
    Cell Significance Index: 26.4000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1866
    Cell Significance Index: 5.0000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1408
    Cell Significance Index: 3.0500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1338
    Cell Significance Index: 24.1200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1309
    Cell Significance Index: 57.8700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1170
    Cell Significance Index: 3.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1121
    Cell Significance Index: 15.4000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1008
    Cell Significance Index: 4.5700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.0953
    Cell Significance Index: 1.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0736
    Cell Significance Index: 40.2100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0505
    Cell Significance Index: 2.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0499
    Cell Significance Index: 3.0700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0363
    Cell Significance Index: 0.7700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0279
    Cell Significance Index: 1.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0242
    Cell Significance Index: 15.3400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0217
    Cell Significance Index: 40.7900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0157
    Cell Significance Index: 28.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0122
    Cell Significance Index: 18.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0092
    Cell Significance Index: 12.5000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0066
    Cell Significance Index: 3.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0044
    Cell Significance Index: -0.2300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0075
    Cell Significance Index: -0.3300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0135
    Cell Significance Index: -0.4800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0181
    Cell Significance Index: -13.2500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0206
    Cell Significance Index: -3.0000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0209
    Cell Significance Index: -15.4500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0213
    Cell Significance Index: -0.5700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0230
    Cell Significance Index: -17.4100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0274
    Cell Significance Index: -1.8500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0287
    Cell Significance Index: -16.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0296
    Cell Significance Index: -5.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0338
    Cell Significance Index: -21.0800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0393
    Cell Significance Index: -1.4900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0403
    Cell Significance Index: -2.8500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0544
    Cell Significance Index: -6.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0567
    Cell Significance Index: -16.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0574
    Cell Significance Index: -3.7000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0582
    Cell Significance Index: -1.2400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0636
    Cell Significance Index: -1.0900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0832
    Cell Significance Index: -8.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0974
    Cell Significance Index: -20.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1080
    Cell Significance Index: -5.0800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1130
    Cell Significance Index: -1.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1181
    Cell Significance Index: -13.5400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1184
    Cell Significance Index: -15.3000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1417
    Cell Significance Index: -4.5400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1484
    Cell Significance Index: -3.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1588
    Cell Significance Index: -16.5400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1899
    Cell Significance Index: -3.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1908
    Cell Significance Index: -14.2200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.2033
    Cell Significance Index: -4.9600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2098
    Cell Significance Index: -16.6200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.2152
    Cell Significance Index: -1.3000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2171
    Cell Significance Index: -13.3100
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.2176
    Cell Significance Index: -3.3100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2197
    Cell Significance Index: -5.9800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2452
    Cell Significance Index: -5.8800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2519
    Cell Significance Index: -2.3200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2520
    Cell Significance Index: -7.2300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2615
    Cell Significance Index: -3.8600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2719
    Cell Significance Index: -4.5500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3125
    Cell Significance Index: -16.4100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3305
    Cell Significance Index: -4.9800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3343
    Cell Significance Index: -3.9900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3424
    Cell Significance Index: -10.0600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3480
    Cell Significance Index: -17.5900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3590
    Cell Significance Index: -7.6200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3611
    Cell Significance Index: -11.5000
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.3634
    Cell Significance Index: -5.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3681
    Cell Significance Index: -12.7900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3700
    Cell Significance Index: -9.7300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3738
    Cell Significance Index: -10.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Desumoylase activity:** SENP1 is a specific desumoylase that cleaves SMTs from target proteins, leading to the removal of sumoylation tags. 2. **High expression levels:** SENP1 is significantly expressed in various cell types, including germ cells, neurons, and intestinal epithelial cells. 3. **Multiple cellular functions:** SENP1 is involved in regulating protein stability, transcriptional activity, and apoptosis, among other cellular processes. 4. **Signaling pathway involvement:** SENP1 is implicated in various signaling pathways, including the apoptotic signaling pathway, transcriptional regulation, and protein metabolism. **Pathways and Functions:** 1. **Apoptotic signaling pathway:** SENP1 is involved in regulating the apoptotic process by desumoylating target proteins that are involved in apoptosis. 2. **Transcriptional regulation:** SENP1 influences transcriptional activity by desumoylating transcription factors and other regulatory proteins. 3. **Protein metabolism:** SENP1 regulates protein degradation and stability by desumoylating target proteins. 4. **Signaling by Rho GTPases:** SENP1 is involved in the regulation of Rho GTPase signaling pathways, which play a crucial role in various cellular processes, including cell migration, cytoskeleton organization, and apoptosis. **Clinical Significance:** 1. **Cancer research:** SENP1 has been implicated in various cancers, including breast, lung, and colon cancer, where it is involved in regulating tumor cell proliferation, apoptosis, and metastasis. 2. **Neurological disorders:** SENP1 has been linked to neurological disorders, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, where it influences protein aggregation, neuronal survival, and synaptic function. 3. **Immune system regulation:** SENP1 plays a crucial role in regulating immune responses, including the activation of immune cells and the modulation of inflammation. 4. **Pharmacological targeting:** SENP1 is a potential therapeutic target for various diseases, including cancer, neurological disorders, and inflammatory conditions, where it can be targeted by small molecule inhibitors. In conclusion, SENP1 is a multifunctional enzyme that plays a critical role in regulating various cellular processes, including protein stability, transcriptional activity, and apoptosis. Its involvement in multiple signaling pathways and its high expression levels in various cell types make it a promising target for therapeutic interventions in various diseases.

Genular Protein ID: 2305971876

Symbol: SENP1_HUMAN

Name: Sentrin-specific protease 1

UniProtKB Accession Codes:

Q9P0U3 A8K7P5 Q86XC8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10652325

Title: Differential regulation of sentrinized proteins by a novel sentrin-specific protease.

PubMed ID: 10652325

DOI: 10.1074/jbc.275.5.3355

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14563852

Title: Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1.

PubMed ID: 14563852

DOI: 10.1074/jbc.m306195200

PubMed ID: 15199155

Title: SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1.

PubMed ID: 15199155

DOI: 10.1128/mcb.24.13.6021-6028.2004

PubMed ID: 15487983

Title: Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1.

PubMed ID: 15487983

DOI: 10.1042/bj20041210

PubMed ID: 16253240

Title: Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.

PubMed ID: 16253240

DOI: 10.1016/j.febslet.2005.10.010

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21965678

Title: SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function.

PubMed ID: 21965678

DOI: 10.1074/jbc.m111.267237

PubMed ID: 21829689

Title: SUMOylation of DEC1 protein regulates its transcriptional activity and enhances its stability.

PubMed ID: 21829689

DOI: 10.1371/journal.pone.0023046

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23160374

Title: CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-alpha.

PubMed ID: 23160374

DOI: 10.1038/onc.2012.518

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24943844

Title: SUMOylation of GPS2 protein regulates its transcription-suppressing function.

PubMed ID: 24943844

DOI: 10.1091/mbc.e13-12-0733

PubMed ID: 25406032

Title: Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage.

PubMed ID: 25406032

DOI: 10.1038/ncomms6483

PubMed ID: 29506078

Title: SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function.

PubMed ID: 29506078

DOI: 10.1093/nar/gky156

PubMed ID: 34048572

Title: Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response.

PubMed ID: 34048572

DOI: 10.1093/nar/gkab415

PubMed ID: 37257451

Title: RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity.

PubMed ID: 37257451

DOI: 10.1016/j.molcel.2023.05.010

PubMed ID: 16553580

Title: The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing.

PubMed ID: 16553580

DOI: 10.1042/bj20052030

PubMed ID: 16712526

Title: Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease.

PubMed ID: 16712526

DOI: 10.1042/bj20060526

PubMed ID: 17099698

Title: SUMO protease SENP1 induces isomerization of the scissile peptide bond.

PubMed ID: 17099698

DOI: 10.1038/nsmb1172

Sequence Information:

  • Length: 644
  • Mass: 73481
  • Checksum: 941951A8B341EC64
  • Sequence:
    • MDDIADRMRM DAGEVTLVNH NSVFKTHLLP QTGFPEDQLS LSDQQILSSR QGHLDRSFTC 
STRSAAYNPS YYSDNPSSDS FLGSGDLRTF GQSANGQWRN STPSSSSSLQ KSRNSRSLYL 
ETRKTSSGLS NSFAGKSNHH CHVSAYEKSF PIKPVPSPSW SGSCRRSLLS PKKTQRRHVS 
TAEETVQEEE REIYRQLLQM VTGKQFTIAK PTTHFPLHLS RCLSSSKNTL KDSLFKNGNS 
CASQIIGSDT SSSGSASILT NQEQLSHSVY SLSSYTPDVA FGSKDSGTLH HPHHHHSVPH 
QPDNLAASNT QSEGSDSVIL LKVKDSQTPT PSSTFFQAEL WIKELTSVYD SRARERLRQI 
EEQKALALQL QNQRLQEREH SVHDSVELHL RVPLEKEIPV TVVQETQKKG HKLTDSEDEF 
PEITEEMEKE IKNVFRNGNQ DEVLSEAFRL TITRKDIQTL NHLNWLNDEI INFYMNMLME 
RSKEKGLPSV HAFNTFFFTK LKTAGYQAVK RWTKKVDVFS VDILLVPIHL GVHWCLAVVD 
FRKKNITYYD SMGGINNEAC RILLQYLKQE SIDKKRKEFD TNGWQLFSKK SQEIPQQMNG 
SDCGMFACKY ADCITKDRPI NFTQQHMPYF RKRMVWEILH RKLL

Genular Protein ID: 3213283373

Symbol: Q7Z3G1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z3G1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 RefSeq 1

Sequence Information:

  • Length: 123
  • Mass: 13575
  • Checksum: 4EC4E27EE1EB5A9F
  • Sequence:
    • MRMDAGEVTL VNHNSVFKTH LLPQTGFPED QLSLSDQQIL SSRQGHLDRS FTCSARSAAY 
NPSYYSGPGL GVLARYSWGK MLTFGGHHGV TLMQIRHMAV AGFSSFINFQ IILPQTVFLA 
QAI

Genular Protein ID: 3719458352

Symbol: Q6N001_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6N001

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 ProteomicsDB 1 RefSeq 2

Sequence Information:

  • Length: 162
  • Mass: 17790
  • Checksum: 657C8A42AC76E47C
  • Sequence:
    • MKIPLTATIC LPGSSPPGLC IFAKVSDVKR LEMDDIADRM RMDAGEVTLV NHNSVFKTHL 
LPQTGFPEDQ LSLSDQQILS SRQGHLDRSF TCSTRSAAYN PSYYSGPGLG VLARYSWGKM 
LTFGGHHGVT LMQIRHMAVA GFSSFINFQI ILPQTVFLAQ AI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.