Details for: CERS2

Gene ID: 29956

Symbol: CERS2

Ensembl ID: ENSG00000143418

Description: ceramide synthase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 169.3398
    Cell Significance Index: -26.3400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 89.8506
    Cell Significance Index: -22.7900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 78.1167
    Cell Significance Index: -32.1800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 68.0111
    Cell Significance Index: -27.6300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 66.6776
    Cell Significance Index: -31.4800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 59.3232
    Cell Significance Index: -30.5200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 46.9284
    Cell Significance Index: -31.4900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 28.9607
    Cell Significance Index: -27.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.9830
    Cell Significance Index: -29.5700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.3230
    Cell Significance Index: -24.9800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.6456
    Cell Significance Index: -30.1700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.5306
    Cell Significance Index: -23.1300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.0072
    Cell Significance Index: -8.7700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.3625
    Cell Significance Index: 90.1000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.9505
    Cell Significance Index: 317.2300
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.7210
    Cell Significance Index: 18.2900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5943
    Cell Significance Index: 95.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.4229
    Cell Significance Index: 154.7700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3094
    Cell Significance Index: 35.6400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0881
    Cell Significance Index: 149.4200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.9991
    Cell Significance Index: 11.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9131
    Cell Significance Index: 181.2000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7970
    Cell Significance Index: 55.1200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7808
    Cell Significance Index: 704.9800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7205
    Cell Significance Index: 9.8300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6811
    Cell Significance Index: 50.7600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6635
    Cell Significance Index: 42.8100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5794
    Cell Significance Index: 74.2800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.5289
    Cell Significance Index: 3.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5227
    Cell Significance Index: 64.2700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.5082
    Cell Significance Index: 17.6600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.5006
    Cell Significance Index: 14.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4648
    Cell Significance Index: 253.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4534
    Cell Significance Index: 21.3100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3584
    Cell Significance Index: 64.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3509
    Cell Significance Index: 16.3600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3436
    Cell Significance Index: 44.3900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.3362
    Cell Significance Index: 8.8400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3257
    Cell Significance Index: 9.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3199
    Cell Significance Index: 141.4400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3174
    Cell Significance Index: 54.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2710
    Cell Significance Index: 14.0800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.2417
    Cell Significance Index: 1.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2242
    Cell Significance Index: 6.4600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2083
    Cell Significance Index: 4.3600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.1966
    Cell Significance Index: 3.4800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1716
    Cell Significance Index: 7.7800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1351
    Cell Significance Index: 27.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1258
    Cell Significance Index: 14.8300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1213
    Cell Significance Index: 8.5800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0891
    Cell Significance Index: 16.9600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0838
    Cell Significance Index: 63.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0521
    Cell Significance Index: 18.7000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0342
    Cell Significance Index: 1.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0322
    Cell Significance Index: 3.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0215
    Cell Significance Index: 40.4500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0176
    Cell Significance Index: 0.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0154
    Cell Significance Index: 10.6200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0012
    Cell Significance Index: 2.1300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0010
    Cell Significance Index: 1.5200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0015
    Cell Significance Index: -0.9500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0040
    Cell Significance Index: -2.9200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0067
    Cell Significance Index: -0.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0079
    Cell Significance Index: -4.9200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0127
    Cell Significance Index: -9.4200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0148
    Cell Significance Index: -20.1400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0248
    Cell Significance Index: -2.5300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0296
    Cell Significance Index: -0.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0317
    Cell Significance Index: -17.8900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0467
    Cell Significance Index: -21.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0608
    Cell Significance Index: -6.9600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0686
    Cell Significance Index: -14.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0760
    Cell Significance Index: -21.8800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0940
    Cell Significance Index: -10.9600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0977
    Cell Significance Index: -0.5900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1006
    Cell Significance Index: -2.1800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1206
    Cell Significance Index: -17.5400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1254
    Cell Significance Index: -14.3200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1441
    Cell Significance Index: -2.9900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1444
    Cell Significance Index: -3.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1467
    Cell Significance Index: -4.7000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1504
    Cell Significance Index: -11.5400
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.1613
    Cell Significance Index: -1.0300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1738
    Cell Significance Index: -8.7800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2012
    Cell Significance Index: -5.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2133
    Cell Significance Index: -5.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2423
    Cell Significance Index: -15.2700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2574
    Cell Significance Index: -2.3700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2755
    Cell Significance Index: -28.6900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2896
    Cell Significance Index: -17.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2953
    Cell Significance Index: -7.3800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3224
    Cell Significance Index: -25.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3391
    Cell Significance Index: -19.0300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3497
    Cell Significance Index: -9.3600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3780
    Cell Significance Index: -15.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3782
    Cell Significance Index: -25.4300
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.4114
    Cell Significance Index: -5.7700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4149
    Cell Significance Index: -4.3000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4368
    Cell Significance Index: -26.7800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4550
    Cell Significance Index: -23.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CERS2 is a member of the ceramide synthase family, which is responsible for the formation of ceramides through the condensation of sphingosine and fatty acyl-CoA molecules. The enzyme is characterized by its high specificity for dihydroceramide, a precursor molecule in the ceramide biosynthetic pathway. CERS2 is highly expressed in various tissues, including pneumocytes, epithelial cells, and placental villous trophoblasts, suggesting its importance in maintaining tissue homeostasis and regulating cellular processes. **Pathways and Functions:** CERS2 is involved in several key pathways, including: 1. **Ceramide biosynthetic process:** CERS2 is the primary enzyme responsible for the formation of ceramides, which are essential for various cellular processes, including lipid metabolism, cell signaling, and immune regulation. 2. **Negative regulation of axon regeneration:** CERS2 has been shown to inhibit axon regeneration by suppressing the expression of pro-regenerative genes and promoting the expression of anti-regenerative genes. 3. **Negative regulation of schwann cell migration and proliferation:** CERS2 also regulates the migration and proliferation of schwann cells, which are essential for the maintenance of the peripheral nervous system. 4. **Regulation of lipid metabolic process:** CERS2 is involved in the regulation of lipid metabolism, including the synthesis and degradation of ceramides, which play a crucial role in energy storage and cellular signaling. 5. **Sphingolipid biosynthetic process:** CERS2 is a key component of the sphingolipid biosynthetic pathway, which is essential for the formation of sphingolipids, including ceramides, sphingomyelin, and sphingosine-1-phosphate. **Clinical Significance:** CERS2 has been implicated in various immune-related disorders, including: 1. **Multiple sclerosis:** CERS2 has been shown to be involved in the regulation of axon regeneration and schwann cell migration, which are critical processes in the pathogenesis of multiple sclerosis. 2. **Autoimmune diseases:** CERS2 has been implicated in the regulation of immune cell function and the development of autoimmune diseases, including rheumatoid arthritis and lupus. 3. **Cancer:** CERS2 has been shown to be involved in the regulation of lipid metabolism and cell signaling, which are critical processes in cancer development and progression. 4. **Immobilization stress:** CERS2 has been shown to be involved in the regulation of lipid metabolism and immune cell function in response to immobilization stress. In conclusion, CERS2 is a critical enzyme involved in the biosynthesis of ceramides, which play a pivotal role in various cellular processes, including lipid metabolism, cell signaling, and immune regulation. Further studies are needed to fully elucidate the role of CERS2 in immune-related disorders and to explore its potential as a therapeutic target.

Genular Protein ID: 2337204373

Symbol: CERS2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96G23 D3DV06 Q5SZE5 Q9HD96 Q9NW79

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 100 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 11 Ensembl 2 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 42 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11543633

Title: Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

PubMed ID: 11543633

DOI: 10.1006/geno.2001.6614

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12869556

Title: Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast.

PubMed ID: 12869556

DOI: 10.1074/jbc.m307554200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16263699

Title: Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.

PubMed ID: 16263699

DOI: 10.1074/mcp.m500324-mcp200

PubMed ID: 17977534

Title: Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine.

PubMed ID: 17977534

DOI: 10.1016/j.febslet.2007.10.018

PubMed ID: 18165233

Title: Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.

PubMed ID: 18165233

DOI: 10.1074/jbc.m707386200

PubMed ID: 18541923

Title: 2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length.

PubMed ID: 18541923

DOI: 10.1194/jlr.m800158-jlr200

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19728861

Title: Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response.

PubMed ID: 19728861

DOI: 10.1042/bj20090699

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20937905

Title: ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.

PubMed ID: 20937905

DOI: 10.1073/pnas.1005572107

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22661289

Title: A fluorescent assay for ceramide synthase activity.

PubMed ID: 22661289

DOI: 10.1194/jlr.d025627

PubMed ID: 22144673

Title: Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain.

PubMed ID: 22144673

DOI: 10.1074/jbc.m111.280271

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26887952

Title: Enzyme activities of the ceramide synthases CERS2-6 are regulated by phosphorylation in the C-terminal region.

PubMed ID: 26887952

DOI: 10.1074/jbc.m115.695858

PubMed ID: 29632068

Title: Eleven residues determine the acyl chain specificity of ceramide synthases.

PubMed ID: 29632068

DOI: 10.1074/jbc.ra118.001936

Sequence Information:

  • Length: 380
  • Mass: 44876
  • Checksum: C8CEAF6AAD0B4577
  • Sequence:
    • MLQTLYDYFW WERLWLPVNL TWADLEDRDG RVYAKASDLY ITLPLALLFL IVRYFFELYV 
ATPLAALLNI KEKTRLRAPP NATLEHFYLT SGKQPKQVEV ELLSRQSGLS GRQVERWFRR 
RRNQDRPSLL KKFREASWRF TFYLIAFIAG MAVIVDKPWF YDMKKVWEGY PIQSTIPSQY 
WYYMIELSFY WSLLFSIASD VKRKDFKEQI IHHVATIILI SFSWFANYIR AGTLIMALHD 
SSDYLLESAK MFNYAGWKNT CNNIFIVFAI VFIITRLVIL PFWILHCTLV YPLELYPAFF 
GYYFFNSMMG VLQLLHIFWA YLILRMAHKF ITGKLVEDER SDREETESSE GEEAAAGGGA 
KSRPLANGHP ILNNNHRKND

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.