Details for: HADH
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 169.7898
Cell Significance Index: -26.4100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 94.6605
Cell Significance Index: -24.0100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 76.3785
Cell Significance Index: -36.0600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 71.3587
Cell Significance Index: -28.9900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 66.0011
Cell Significance Index: -33.9500 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 53.8097
Cell Significance Index: -36.1100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 30.6051
Cell Significance Index: -29.2200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 26.4973
Cell Significance Index: -32.6700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 11.1876
Cell Significance Index: -29.9700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.5833
Cell Significance Index: -33.8700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 6.3748
Cell Significance Index: -19.5800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.5685
Cell Significance Index: -7.8100 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.8706
Cell Significance Index: 46.0600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 2.5427
Cell Significance Index: 296.3300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.9751
Cell Significance Index: 321.2300 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.5877
Cell Significance Index: 17.2600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.5614
Cell Significance Index: 81.1100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.2643
Cell Significance Index: 18.9500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.1539
Cell Significance Index: 1041.9200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.0227
Cell Significance Index: 184.3600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.0044
Cell Significance Index: 21.7600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.9716
Cell Significance Index: 67.1900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9644
Cell Significance Index: 74.0100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.9545
Cell Significance Index: 19.9800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.8958
Cell Significance Index: 63.3600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.8808
Cell Significance Index: 22.6400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8163
Cell Significance Index: 22.2200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.8097
Cell Significance Index: 99.5600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.8064
Cell Significance Index: 440.4200 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.7997
Cell Significance Index: 10.0700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.7835
Cell Significance Index: 7.2200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.7229
Cell Significance Index: 143.4600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7114
Cell Significance Index: 142.7100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.6941
Cell Significance Index: 32.3600 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.6854
Cell Significance Index: 88.5500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6800
Cell Significance Index: 80.1900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6672
Cell Significance Index: 66.0000 - Cell Name: peg cell (CL4033014)
Fold Change: 0.6458
Cell Significance Index: 14.9200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.6364
Cell Significance Index: 8.1500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.5076
Cell Significance Index: 69.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4795
Cell Significance Index: 22.5400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4681
Cell Significance Index: 89.0900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.4615
Cell Significance Index: 14.7800 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.4605
Cell Significance Index: 12.1100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4555
Cell Significance Index: 163.4000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4406
Cell Significance Index: 19.9700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.4381
Cell Significance Index: 10.6900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4167
Cell Significance Index: 26.8900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4143
Cell Significance Index: 183.1700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.3361
Cell Significance Index: 11.6800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3186
Cell Significance Index: 40.8400 - Cell Name: sebaceous gland cell (CL2000021)
Fold Change: 0.3053
Cell Significance Index: 0.4000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3009
Cell Significance Index: 8.4100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.3006
Cell Significance Index: 16.8700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.2780
Cell Significance Index: 4.1100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1962
Cell Significance Index: 33.5000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.1787
Cell Significance Index: 4.7800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1268
Cell Significance Index: 87.7300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0857
Cell Significance Index: 3.0100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0625
Cell Significance Index: 1.6800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0615
Cell Significance Index: 4.5800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0465
Cell Significance Index: 2.8600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0349
Cell Significance Index: 65.7300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0286
Cell Significance Index: 20.9900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0124
Cell Significance Index: 9.3800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0080
Cell Significance Index: 3.6500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0027
Cell Significance Index: 0.0500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0051
Cell Significance Index: -3.2600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0060
Cell Significance Index: -3.7700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0073
Cell Significance Index: -11.2300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0081
Cell Significance Index: -14.9700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0138
Cell Significance Index: -0.7200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0154
Cell Significance Index: -11.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0176
Cell Significance Index: -23.9400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0282
Cell Significance Index: -15.9000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0293
Cell Significance Index: -2.9900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0376
Cell Significance Index: -0.9600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0433
Cell Significance Index: -9.1100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0732
Cell Significance Index: -10.6500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0870
Cell Significance Index: -25.0300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1256
Cell Significance Index: -3.1400 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.1269
Cell Significance Index: -1.7800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1339
Cell Significance Index: -15.3400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1787
Cell Significance Index: -14.1500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1865
Cell Significance Index: -4.9800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2005
Cell Significance Index: -13.4800 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2143
Cell Significance Index: -3.6100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2217
Cell Significance Index: -23.0800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2272
Cell Significance Index: -10.0500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.2507
Cell Significance Index: -2.6000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2700
Cell Significance Index: -17.0200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2778
Cell Significance Index: -10.5200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3002
Cell Significance Index: -8.6500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3042
Cell Significance Index: -34.7200 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.3152
Cell Significance Index: -2.5700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3379
Cell Significance Index: -17.7400 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.3495
Cell Significance Index: -5.6400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3567
Cell Significance Index: -21.8700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3711
Cell Significance Index: -10.9000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.4434
Cell Significance Index: -6.0500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1347108401
Symbol: HCDH_HUMAN
Name: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8687463
Title: Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence.
PubMed ID: 8687463
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 29192674
Title: Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.
PubMed ID: 29192674
DOI: 10.1038/cr.2017.149
PubMed ID: 10231530
Title: Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism.
PubMed ID: 10231530
DOI: 10.1021/bi9829027
PubMed ID: 10840044
Title: Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase.
PubMed ID: 10840044
PubMed ID: 16176262
Title: 3-hydroxyacyl-CoA dehydrogenase and short chain 3-hydroxyacyl-CoA dehydrogenase in human health and disease.
PubMed ID: 16176262
PubMed ID: 11489939
Title: Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.
PubMed ID: 11489939
DOI: 10.1172/jci11294
PubMed ID: 16725361
Title: Reye-like syndrome resulting from novel missense mutations in mitochondrial medium- and short-chain l-3-hydroxy-acyl-CoA dehydrogenase.
PubMed ID: 16725361
Sequence Information:
- Length: 314
- Mass: 34294
- Checksum: 0C6F7C01BBCE646A
- Sequence:
MAFVTRQFMR SVSSSSTASA SAKKIIVKHV TVIGGGLMGA GIAQVAAATG HTVVLVDQTE DILAKSKKGI EESLRKVAKK KFAENLKAGD EFVEKTLSTI ATSTDAASVV HSTDLVVEAI VENLKVKNEL FKRLDKFAAE HTIFASNTSS LQITSIANAT TRQDRFAGLH FFNPVPVMKL VEVIKTPMTS QKTFESLVDF SKALGKHPVS CKDTPGFIVN RLLVPYLMEA IRLYERGDAS KEDIDTAMKL GAGYPMGPFE LLDYVGLDTT KFIVDGWHEM DAENPLHQPS PSLNKLVAEN KFGKKTGEGF YKYK
Genular Protein ID: 1726570359
Symbol: B3KTT6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 318
- Mass: 35221
- Checksum: F1BEB5F4ED620D9C
- Sequence:
MCRTALGVTT LQDLGVCWRK EHDPAEMLRV GRAELGGWKP SWEAIVKEVA AATGHTVVLV DQTEDILAKS KKGIEESLRK VAKKKFAENP KAGDEFVEKT LSTIATSTDA ASVVHSTDLV VEAIVENLKV KNELFKRLDK FAAEHTIFAS NTSSLQITSI ANATTRQDRF AGLHFFNPVP VMKLVEVIKT PMTSQKTFES LVDFSKALGK HPVSCKDTPG FIVNRLLVPY LMEAIRLYER GDASKEDIDT AMKLGAGYPM GPFELLDYVG LDTTKFIVDG WHEMDAENPL HQPSPSLNKL VAENKFGKKT GEGFYKYK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.