Details for: NDST1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 160.5321
Cell Significance Index: -24.9700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 96.7500
Cell Significance Index: -24.5400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 53.9055
Cell Significance Index: -25.4500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 20.2440
Cell Significance Index: -24.9600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.3177
Cell Significance Index: -24.9300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.2989
Cell Significance Index: 437.4900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.0428
Cell Significance Index: 206.9500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8688
Cell Significance Index: 174.2900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8500
Cell Significance Index: 767.5100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8499
Cell Significance Index: 138.2300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.6816
Cell Significance Index: 196.1200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6633
Cell Significance Index: 65.6200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.4913
Cell Significance Index: 37.7100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4845
Cell Significance Index: 52.7000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4371
Cell Significance Index: 156.7700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4348
Cell Significance Index: 26.1000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3968
Cell Significance Index: 18.5000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3362
Cell Significance Index: 232.5200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2797
Cell Significance Index: 6.0600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.2498
Cell Significance Index: 14.0200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2475
Cell Significance Index: 17.1200 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.2262
Cell Significance Index: 3.8100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2103
Cell Significance Index: 5.6400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1528
Cell Significance Index: 6.7600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.1242
Cell Significance Index: 4.7100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1162
Cell Significance Index: 51.3900 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.1119
Cell Significance Index: 1.6100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1019
Cell Significance Index: 2.9400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0964
Cell Significance Index: 11.2400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0826
Cell Significance Index: 45.0900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0752
Cell Significance Index: 10.3300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0593
Cell Significance Index: 2.7900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0432
Cell Significance Index: 0.5900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0333
Cell Significance Index: 1.5100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0331
Cell Significance Index: 60.9800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0268
Cell Significance Index: 0.6700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0232
Cell Significance Index: 35.7400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0225
Cell Significance Index: 4.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0141
Cell Significance Index: 26.5800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0113
Cell Significance Index: 0.7600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0110
Cell Significance Index: 15.0200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0007
Cell Significance Index: 0.0400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0052
Cell Significance Index: -0.6300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0055
Cell Significance Index: -3.4800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0098
Cell Significance Index: -0.6200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0177
Cell Significance Index: -8.0400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0221
Cell Significance Index: -16.1900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0240
Cell Significance Index: -18.1300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0256
Cell Significance Index: -18.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0304
Cell Significance Index: -0.8500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0344
Cell Significance Index: -5.8800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0365
Cell Significance Index: -4.7200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0379
Cell Significance Index: -5.5100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0407
Cell Significance Index: -22.9600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0451
Cell Significance Index: -28.1500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0566
Cell Significance Index: -1.5100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0701
Cell Significance Index: -4.9600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0795
Cell Significance Index: -10.1900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0833
Cell Significance Index: -9.5500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1172
Cell Significance Index: -1.7300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1280
Cell Significance Index: -26.9600 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1324
Cell Significance Index: -0.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1341
Cell Significance Index: -13.7000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1411
Cell Significance Index: -3.0900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1505
Cell Significance Index: -11.2200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2022
Cell Significance Index: -23.8500 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2047
Cell Significance Index: -2.2300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2270
Cell Significance Index: -23.6400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2449
Cell Significance Index: -6.4400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2724
Cell Significance Index: -14.1500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2802
Cell Significance Index: -4.6900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2881
Cell Significance Index: -14.5600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2909
Cell Significance Index: -23.0400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2933
Cell Significance Index: -5.7300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3292
Cell Significance Index: -20.1800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3306
Cell Significance Index: -9.0000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.3340
Cell Significance Index: -11.7400 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3481
Cell Significance Index: -7.4400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3571
Cell Significance Index: -9.1800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3584
Cell Significance Index: -23.1200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3702
Cell Significance Index: -10.5700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3821
Cell Significance Index: -20.0600 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.3921
Cell Significance Index: -6.2900 - Cell Name: medium spiny neuron (CL1001474)
Fold Change: -0.4009
Cell Significance Index: -5.4100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.4370
Cell Significance Index: -10.4800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4456
Cell Significance Index: -9.4900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4490
Cell Significance Index: -9.3200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4587
Cell Significance Index: -14.6100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.4692
Cell Significance Index: -6.7200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.4730
Cell Significance Index: -7.1300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4792
Cell Significance Index: -7.0800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4899
Cell Significance Index: -16.0400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5075
Cell Significance Index: -17.7800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5151
Cell Significance Index: -17.9000 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.5327
Cell Significance Index: -9.2100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.5344
Cell Significance Index: -11.5500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5479
Cell Significance Index: -17.5500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5480
Cell Significance Index: -11.6300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.5505
Cell Significance Index: -15.7800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.5595
Cell Significance Index: -20.5400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1459161897
Symbol: NDST1_HUMAN
Name: Glucosaminyl N-deacetylase/N-sulfotransferase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7601448
Title: Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1.
PubMed ID: 7601448
PubMed ID: 9230113
Title: Localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase to the trans-Golgi network.
PubMed ID: 9230113
DOI: 10.1042/bj3250351
PubMed ID: 19880432
Title: Identification and functional analyses of 11,769 full-length human cDNAs focused on alternative splicing.
PubMed ID: 19880432
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9744796
Title: A role of Lys614 in the sulfotransferase activity of human heparan sulfate N-deacetylase/N-sulfotransferase.
PubMed ID: 9744796
PubMed ID: 22660413
Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
PubMed ID: 22660413
DOI: 10.1038/ncb2502
PubMed ID: 35137078
Title: A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation.
PubMed ID: 35137078
PubMed ID: 10196134
Title: Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/N-sulfotransferase 1.
PubMed ID: 10196134
PubMed ID: 25125150
Title: NDST1 missense mutations in autosomal recessive intellectual disability.
PubMed ID: 25125150
DOI: 10.1002/ajmg.a.36723
Sequence Information:
- Length: 882
- Mass: 100868
- Checksum: D4B716B84A0BF4C4
- Sequence:
MPALACLRRL CRHVSPQAVL FLLFIFCLFS VFISAYYLYG WKRGLEPSAD APEPDCGDPP PVAPSRLLPL KPVQAATPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL AKTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRAHIP NFTFNLGYSG KFFHTGTNAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WSIRVTSTEE YPHLKPARYR RGFIHNGIMV LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELFLTVLL NPISIFMTHL SNYGNDRLGL YTFKHLVRFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKVL TILINPADRA YSWYQHQRAH DDPVALKYTF HEVITAGSDA SSKLRALQNR CLVPGWYATH IERWLSAYHA NQILVLDGKL LRTEPAKVMD MVQKFLGVTN TIDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM DLDSRAFLKD YYRDHNIELS KLLYKMGQTL PTWLREDLQN TR
Genular Protein ID: 1776505003
Symbol: A8K8T3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 882
- Mass: 100838
- Checksum: 973888A8CDAFA604
- Sequence:
MPALACLRRL CRHVSPQAVL FLLFIFCLFS VFISAYYLYG WKRGLEPSAD APEPDCGDPP PVAPSRLLPL KPVQAATPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG DMPTLTDKGR GRFALIIYEN ILKYVNLDAW DRELLDKYCV AYGVGIIGFF KANENSLLSA QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL ARTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRAHIP NFTFNLGYSG KFFHTGTNAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WSIRVTSTEE YPHLKPARYR RGFIHNGIMV LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELSLTVLL NPISIFMTHL SNYGNDRLGL YTFKHLVRFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HEDIWSKEKT CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKVL TILINPADRA YSWYQHQRAH DDPVALKYTF HEVITAGSDA SSKLRALQNR CLVPGWYATH IERWLSAYHA NQILVLDGKL LRTEPAKVMD MVQKFLGVTN TIDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM DLDSRAFLKD YYRDHNIELS KLLYKMGQTL PTWLREDLQN TR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.