Details for: CFI

Gene ID: 3426

Symbol: CFI

Ensembl ID: ENSG00000205403

Description: complement factor I

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: 2
    Marker Score: 1256
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.78
    Marker Score: 570
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.7
    Marker Score: 7314
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.63
    Marker Score: 3265
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.61
    Marker Score: 18171
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.51
    Marker Score: 15154
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.5
    Marker Score: 4090
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.47
    Marker Score: 7878
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.42
    Marker Score: 4646
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.37
    Marker Score: 2203
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.34
    Marker Score: 852
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.33
    Marker Score: 5759
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 1.26
    Marker Score: 1743
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.25
    Marker Score: 3262
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.21
    Marker Score: 4281
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.19
    Marker Score: 7716
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.18
    Marker Score: 252
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.17
    Marker Score: 3127
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.16
    Marker Score: 6906
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.16
    Marker Score: 7477
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.14
    Marker Score: 1210
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.13
    Marker Score: 4725
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.13
    Marker Score: 2847
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.12
    Marker Score: 1141
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.11
    Marker Score: 1151
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251756
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.03
    Marker Score: 35851
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.03
    Marker Score: 1463
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.02
    Marker Score: 779
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.01
    Marker Score: 378
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71775
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48001
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 0.98
    Marker Score: 395
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.98
    Marker Score: 1429
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30405
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.97
    Marker Score: 579
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 455
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.95
    Marker Score: 825
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2408
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.94
    Marker Score: 225
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 368
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.91
    Marker Score: 962
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2737
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.9
    Marker Score: 5877
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.9
    Marker Score: 907
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.89
    Marker Score: 321
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.88
    Marker Score: 1481
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 0.87
    Marker Score: 788
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.87
    Marker Score: 781
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5265
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.86
    Marker Score: 909
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4890
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 0.85
    Marker Score: 206
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 0.84
    Marker Score: 723
  • Cell Name: cardiac mesenchymal cell (CL0000569)
    Fold Change: 0.84
    Marker Score: 206
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.84
    Marker Score: 213
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.83
    Marker Score: 1350
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.83
    Marker Score: 1220
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 0.82
    Marker Score: 1133
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.79
    Marker Score: 386
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.79
    Marker Score: 851
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.79
    Marker Score: 154
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.78
    Marker Score: 224
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.77
    Marker Score: 381
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.76
    Marker Score: 214
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.76
    Marker Score: 389
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 391
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 0.74
    Marker Score: 392
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.71
    Marker Score: 652
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.71
    Marker Score: 276
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.71
    Marker Score: 443
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.71
    Marker Score: 2959
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 177
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.68
    Marker Score: 844
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 0.67
    Marker Score: 1118
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.67
    Marker Score: 3515
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.64
    Marker Score: 233
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.64
    Marker Score: 10305
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.64
    Marker Score: 422
  • Cell Name: tracheobronchial goblet cell (CL0019003)
    Fold Change: 0.63
    Marker Score: 172
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.62
    Marker Score: 480
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.62
    Marker Score: 958
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.61
    Marker Score: 972
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.61
    Marker Score: 273
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6
    Marker Score: 386
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.58
    Marker Score: 1422.5
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 0.58
    Marker Score: 134
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.58
    Marker Score: 1050
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.57
    Marker Score: 549
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.56
    Marker Score: 283
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.56
    Marker Score: 654
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.55
    Marker Score: 147
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.55
    Marker Score: 543
  • Cell Name: adipose microvascular endothelial cell (CL2000072)
    Fold Change: 0.55
    Marker Score: 164
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.55
    Marker Score: 1248
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.55
    Marker Score: 1292
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.54
    Marker Score: 172
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.53
    Marker Score: 284

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Other Information

**Key characteristics:** * CFI is a large protein with a molecular weight of approximately 150 kDa. * It is a glycoprotein composed of three identical subunits. * It is produced by the liver and is secreted by epithelial cells and macrophages. * It is a key regulator of inflammation and immune responses. **Pathways and functions:** * CFI is involved in the classical pathway of the complement system, a complex cascade of protein-protein interactions that lead to the formation of membrane attack complexes that can damage target cells. * It is expressed in high levels in the kidney, where it helps to regulate blood pressure and inflammation. * It is also expressed in the lungs, where it is involved in the regulation of inflammation in the airways. * CFI is a major regulator of immune responses, and its dysfunction can lead to a variety of diseases, including autoimmune disorders and infections. **Clinical significance:** * Mutations in the CFI gene have been linked to a number of human diseases, including systemic sclerosis, rheumatoid arthritis, and liver disease. * CFI inhibitors are being investigated as potential treatments for these diseases. * CFI is a promising target for the development of new drugs that are used to treat inflammatory diseases.

Genular Protein ID: 2818594775

Symbol: CFAI_HUMAN

Name: Complement factor I

UniProtKB Accession Codes:

P05156 O60442

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CPTAC 3 CTD 1 ChEBI 12 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EC 2 EMBL 4 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 4 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 17 KEGG 1 MANE-Select 1 MEROPS 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 6 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PROSITE 7 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SWISS-2DPAGE 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2954545

Title: Characterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones.

PubMed ID: 2954545

DOI: 10.1042/bj2420849

PubMed ID: 2956252

Title: Human complement factor I: analysis of cDNA-derived primary structure and assignment of its gene to chromosome 4.

PubMed ID: 2956252

DOI: 10.1016/s0021-9258(18)61076-2

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 9479036

Title: Cloning and characterization of the promoter for the human complement factor I (C3b/C4b inactivator) gene.

PubMed ID: 9479036

DOI: 10.1016/s0378-1119(97)00632-x

PubMed ID: 6444659

Title: Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes.

PubMed ID: 6444659

DOI: 10.1084/jem.151.3.501

PubMed ID: 7360115

Title: The physiological breakdown of the third component of human complement.

PubMed ID: 7360115

DOI: 10.1016/0161-5890(80)90119-4

PubMed ID: 6327681

Title: Biosynthesis and postsynthetic processing of human C3b/C4b inactivator (factor I) in three hepatoma cell lines.

PubMed ID: 6327681

DOI: 10.1016/s0021-9258(20)82168-1

PubMed ID: 2141838

Title: Regulation of proteolytic activity of complement factor I by pH: C3b/C4b receptor (CR1) and membrane cofactor protein (MCP) have different pH optima for factor I-mediated cleavage of C3b.

PubMed ID: 2141838

DOI: 10.1093/oxfordjournals.jbchem.a123044

PubMed ID: 7672128

Title: Beta-sheet secondary structure of an LDL receptor domain from complement factor I by consensus structure predictions and spectroscopy.

PubMed ID: 7672128

DOI: 10.1016/0014-5793(95)00916-w

PubMed ID: 9291131

Title: Interactions between human complement components factor H, factor I and C3b.

PubMed ID: 9291131

DOI: 10.1042/bj3260553

PubMed ID: 9605165

Title: Interaction of vaccinia virus complement control protein with human complement proteins: factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway.

PubMed ID: 9605165

PubMed ID: 12055245

Title: Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells.

PubMed ID: 12055245

DOI: 10.4049/jimmunol.168.12.6298

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17320177

Title: Human keratinocytes produce the complement inhibitor factor I: Synthesis is regulated by interferon-gamma.

PubMed ID: 17320177

DOI: 10.1016/j.molimm.2007.01.007

PubMed ID: 18544012

Title: Staphylococcus aureus clumping factor A binds to complement regulator factor I and increases factor I cleavage of C3b.

PubMed ID: 18544012

DOI: 10.1086/588825

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 21768352

Title: Structural basis for complement factor I control and its disease-associated sequence polymorphisms.

PubMed ID: 21768352

DOI: 10.1073/pnas.1102167108

PubMed ID: 28671664

Title: Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.

PubMed ID: 28671664

DOI: 10.1038/nsmb.3427

PubMed ID: 8613545

Title: The molecular basis of hereditary complement factor I deficiency.

PubMed ID: 8613545

DOI: 10.1172/jci118515

PubMed ID: 12562389

Title: Molecular characterization of homozygous hereditary factor I deficiency.

PubMed ID: 12562389

DOI: 10.1046/j.1365-2249.2003.02077.x

PubMed ID: 15173250

Title: Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome.

PubMed ID: 15173250

DOI: 10.1136/jmg.2004.019083

PubMed ID: 16621965

Title: Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.

PubMed ID: 16621965

DOI: 10.1182/blood-2005-10-007252

PubMed ID: 17018561

Title: Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome.

PubMed ID: 17018561

DOI: 10.1136/jmg.2006.045328

PubMed ID: 17106690

Title: A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome.

PubMed ID: 17106690

DOI: 10.1007/s00467-006-0320-2

PubMed ID: 20513133

Title: Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.

PubMed ID: 20513133

DOI: 10.1002/humu.21256

PubMed ID: 23685748

Title: A functional variant in the CFI gene confers a high risk of age-related macular degeneration.

PubMed ID: 23685748

DOI: 10.1038/ng.2640

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 583
  • Mass: 65750
  • Checksum: F06070EFE6B572A1
  • Sequence:
    • MKLLHVFLLF LCFHLRFCKV TYTSQEDLVE KKCLAKKYTH LSCDKVFCQP WQRCIEGTCV 
CKLPYQCPKN GTAVCATNRR SFPTYCQQKS LECLHPGTKF LNNGTCTAEG KFSVSLKHGN 
TDSEGIVEVK LVDQDKTMFI CKSSWSMREA NVACLDLGFQ QGADTQRRFK LSDLSINSTE 
CLHVHCRGLE TSLAECTFTK RRTMGYQDFA DVVCYTQKAD SPMDDFFQCV NGKYISQMKA 
CDGINDCGDQ SDELCCKACQ GKGFHCKSGV CIPSQYQCNG EVDCITGEDE VGCAGFASVT 
QEETEILTAD MDAERRRIKS LLPKLSCGVK NRMHIRRKRI VGGKRAQLGD LPWQVAIKDA 
SGITCGGIYI GGCWILTAAH CLRASKTHRY QIWTTVVDWI HPDLKRIVIE YVDRIIFHEN 
YNAGTYQNDI ALIEMKKDGN KKDCELPRSI PACVPWSPYL FQPNDTCIVS GWGREKDNER 
VFSLQWGEVK LISNCSKFYG NRFYEKEMEC AGTYDGSIDA CKGDSGGPLV CMDANNVTYV 
WGVVSWGENC GKPEFPGVYT KVANYFDWIS YHVGRPFISQ YNV

Genular Protein ID: 3308021736

Symbol: Q8WW88_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8WW88

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 Gene3D 3 GenomeRNAi 1 InterPro 11 NCBI Taxonomy 1 OrthoDB 1 PANTHER 1 PRINTS 1 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SMART 3 SMR 1 SUPFAM 3

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 377
  • Mass: 42432
  • Checksum: D5B65AFBEEE9B86C
  • Sequence:
    • MKLLHVFLLF LCFHLRFCKV TYTSQEDLVE KKCLAKKYTH LSCDKVFCQP WQRCIEGTCV 
CKLPYQCPKN GTAVCATNRR SFPTYCQQKS LECLHPGTKF LNNGTCTAEG KFSVSLKHGN 
TDSEGIVEVK LVDQDKTMFI CKSSWSMREA NVACLDLGFQ QGADTQRRFK LSDLSINSTE 
CLHVHCRGLE TSLAECTFTK RRTMGYQDFA DVVCYTQKAD SPMDDFFQCV NGKYISQMKA 
CDGINDCGDQ SDELCCKACQ GKGFHCKSGV CIPSQYQCNG EVDCITGEDE VGCAGFASVA 
QEETEILTAD MDAERRRIKS LLPKLSCGVK NRMHIRRKRI VGGKRAQLGK MKQISLDIFK 
GLHRVYAILE FCCIILK

Genular Protein ID: 1790138657

Symbol: A8K3L0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K3L0

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 4 Genevisible 1 GenomeRNAi 1 InterPro 17 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 10 PROSITE-ProRule 2 Pfam 5 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 1 SMART 4 SUPFAM 4

Sequence Information:

  • Length: 583
  • Mass: 65721
  • Checksum: 343FF30388AAE69F
  • Sequence:
    • MKLLHVFLLF LCFHLRFCKV TYTSQEDLVE KKCLAKKYTH LSCDKVFCQP WQRCIEGTCV 
CKLPYQCPKN GTAVCATNRR SFPTYCQQKS LECLHPGTKF LNNGTCTAEG KFSVSLKHGN 
TDSEGIVEVE LVDQDKTMFI CKSSWSMREA NVACLDLGFQ QGADTQRRFK LSDLSINSTE 
CLHVHCRGLE TSLAECTFTK RRTMGYQDFA DVVCYTQKAD SPMDDFFQCV NGKYISQMKA 
CDGINDCGDQ SDELCCKACQ GKGFHCKSGV CIPSQYQCNG EVDCITGEDE VGCAGFASVA 
QEETEILTAD MDAERRRIKS LLPKLSCGVK NRMHIRRKRI VGGKRAQLGD LPWQVAIKDA 
SGITCGGIYI GGCWILTAAH CLRASKTHRY QIWTTVVDWI HPDLKRIVIE YVDRIIFHEN 
YNAGTYQNDI ALIEMKKDGN KKDCELPRSI PACVPWSPYL FQPNDTCIVS GWGREKDNER 
VFSLQWGEVK LISNCSKFYG NRFYEKEMEC AGTYDGSIDA CKGDSGGPLV CMDANNVTYV 
WGVVSWGENC GKPEFPGVYT KVANYFDWIS YHVGRPFISQ YNV

Genular Protein ID: 1809831614

Symbol: B4DRF2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DRF2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 4 GenomeRNAi 1 InterPro 17 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 10 PROSITE-ProRule 2 Pfam 5 RefSeq 1 RuleBase 1 SAM 1 SMART 4 SUPFAM 4

Sequence Information:

  • Length: 591
  • Mass: 66695
  • Checksum: CA49C95543EE7085
  • Sequence:
    • MKLLHVFLLF LCFHLRFCKV TYTSQEDLVE KKCLAKKYTH LSCDKVFCQP WQRCIEGTCV 
CKLPYQCPKN GTAVCATNRR SFPTYCQQKS LECLHPGTKF LNNGTCTAEG KFSVSLKHGN 
TDSEEIVEVK LVDQDKTMFI CKSSWSMREA NVACLDLGFQ QGADTQRRFK LSDLSINSTE 
CLHVHCRGLE TSLAECTFTK RRTMGYQDFA DVVCYTQKAD SPMDDFFQCV NGKYISQMKA 
CDGINDCGDQ SDELCCKACQ GRGFHCKSGV CIPSQYQCNG EVDCITGEDE VGCAAARHPT 
IQGFASVAQE ETEILTADMD AERRRIKSLL PKLSCGVKNR MHIRRKRIVG GKRAQLGDLP 
WQVAIKDASG ITCGGIYIGG CWILTAAHCL RASKTHRYQI WTTVVDWIHP DLKRIVIEYV 
DRIIFHENYN AGTYQNDIAL IEMKKDGNKK DCELPRSIPA CVPWSPYLFQ PNDTCIVSGW 
GREKDNERVF SLQWGEVKLI SNCSKFYGNR FYEKEMECAG TYDGSIDACK GDSGGPLVCM 
DANNVTYVWG VVSWGENCGK PEFPGVYTKV ANYFDWISYH VGRPFISQYN V

Genular Protein ID: 2845088494

Symbol: G3XAM2_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3XAM2

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 2 GO 3 Gene3D 4 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 17 MEROPS 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 10 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 4 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 576
  • Mass: 65060
  • Checksum: AB001AED6C1BF94A
  • Sequence:
    • MKLLHVFLLF LCFHLRFCKV TYTSQEDLVE KKCLAKKYTH LSCDKVFCQP WQRCIEGTCV 
CKLPYQCPKN GTAVCATNRR SFPTYCQQKS LECLHPGTKF LNNGTCTAEG KFSVSLKHGN 
TDSEGIVEVK LVDQDKTMFI CKSSWSMREA NVACLDLGFQ QGADTQRRFK LSDLSINSTE 
CLHVHCRGLE TSLAECTFTK RRTMGYQDFA DVVCYTQKAD SPMDDFFQCV NGKYISQMKA 
CDGINDCGDQ SDELCCKACQ GKGFHCKSGV CIPSQYQCNG EVDCITGEDE VGCAEETEIL 
TADMDAERRR IKSLLPKLSC GVKNRMHIRR KRIVGGKRAQ LGDLPWQVAI KDASGITCGG 
IYIGGCWILT AAHCLRASKT HRYQIWTTVV DWIHPDLKRI VIEYVDRIIF HENYNAGTYQ 
NDIALIEMKK DGNKKDCELP RSIPACVPWS PYLFQPNDTC IVSGWGREKD NERVFSLQWG 
EVKLISNCSK FYGNRFYEKE MECAGTYDGS IDACKGDSGG PLVCMDANNV TYVWGVVSWG 
ENCGKPEFPG VYTKVANYFD WISYHVGRPF ISQYNV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.