Details for: IGHMBP2

Gene ID: 3508

Symbol: IGHMBP2

Ensembl ID: ENSG00000132740

Description: immunoglobulin mu DNA binding protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 71.8119
    Cell Significance Index: -11.1700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 45.5758
    Cell Significance Index: -11.5600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 32.6741
    Cell Significance Index: -13.4600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 27.7164
    Cell Significance Index: -11.2600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 27.7047
    Cell Significance Index: -13.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.7814
    Cell Significance Index: -12.0600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.6326
    Cell Significance Index: -12.4100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.1120
    Cell Significance Index: -12.2800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.6684
    Cell Significance Index: -5.8400
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.7859
    Cell Significance Index: 12.9500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6907
    Cell Significance Index: 68.3300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5732
    Cell Significance Index: 517.5500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5211
    Cell Significance Index: 7.1100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4366
    Cell Significance Index: 19.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4242
    Cell Significance Index: 85.1000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4043
    Cell Significance Index: 43.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4031
    Cell Significance Index: 11.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3811
    Cell Significance Index: 22.8800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3666
    Cell Significance Index: 59.6300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3479
    Cell Significance Index: 18.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3417
    Cell Significance Index: 67.8100
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.3329
    Cell Significance Index: 2.2100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2718
    Cell Significance Index: 31.6700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2234
    Cell Significance Index: 4.8400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.2144
    Cell Significance Index: 3.4400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2036
    Cell Significance Index: 14.0800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2027
    Cell Significance Index: 5.2100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1990
    Cell Significance Index: 35.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1729
    Cell Significance Index: 62.0100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1709
    Cell Significance Index: 13.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1535
    Cell Significance Index: 106.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1506
    Cell Significance Index: 9.4900
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.1343
    Cell Significance Index: 1.8900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1336
    Cell Significance Index: 6.2300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1317
    Cell Significance Index: 3.6800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0981
    Cell Significance Index: 1.4700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0939
    Cell Significance Index: 11.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0888
    Cell Significance Index: 3.1200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0751
    Cell Significance Index: 41.0300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0729
    Cell Significance Index: 10.0100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0496
    Cell Significance Index: 3.2000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0376
    Cell Significance Index: 0.8000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0293
    Cell Significance Index: 12.9600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0228
    Cell Significance Index: 1.4000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0216
    Cell Significance Index: 0.5800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0179
    Cell Significance Index: 3.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0159
    Cell Significance Index: 7.2400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0121
    Cell Significance Index: 1.5500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0082
    Cell Significance Index: 0.1400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0082
    Cell Significance Index: 15.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0032
    Cell Significance Index: 5.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0028
    Cell Significance Index: 4.2800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0011
    Cell Significance Index: -0.0300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0011
    Cell Significance Index: -0.0500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0017
    Cell Significance Index: -2.2800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0029
    Cell Significance Index: -0.5500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0037
    Cell Significance Index: -2.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0077
    Cell Significance Index: -0.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0113
    Cell Significance Index: -8.3100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0134
    Cell Significance Index: -10.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0143
    Cell Significance Index: -10.5600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0154
    Cell Significance Index: -0.8100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0206
    Cell Significance Index: -0.7800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0210
    Cell Significance Index: -11.8300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0217
    Cell Significance Index: -13.5800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0245
    Cell Significance Index: -1.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0328
    Cell Significance Index: -3.7600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0358
    Cell Significance Index: -3.6600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0367
    Cell Significance Index: -10.5700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0380
    Cell Significance Index: -1.0400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0463
    Cell Significance Index: -3.1100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0509
    Cell Significance Index: -6.5800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0521
    Cell Significance Index: -1.0800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0525
    Cell Significance Index: -7.6300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0596
    Cell Significance Index: -2.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0663
    Cell Significance Index: -13.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0712
    Cell Significance Index: -5.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0824
    Cell Significance Index: -2.0600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0831
    Cell Significance Index: -1.3900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0839
    Cell Significance Index: -8.7400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1045
    Cell Significance Index: -1.7600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1088
    Cell Significance Index: -2.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1090
    Cell Significance Index: -3.4900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1179
    Cell Significance Index: -3.3800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1189
    Cell Significance Index: -3.1800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1204
    Cell Significance Index: -7.3800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1405
    Cell Significance Index: -11.1300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1430
    Cell Significance Index: -4.9700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1513
    Cell Significance Index: -7.8800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1571
    Cell Significance Index: -4.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1605
    Cell Significance Index: -3.3600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1729
    Cell Significance Index: -5.0800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1906
    Cell Significance Index: -4.8700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1931
    Cell Significance Index: -2.8500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1932
    Cell Significance Index: -3.7700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2253
    Cell Significance Index: -6.4300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2264
    Cell Significance Index: -5.4300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2286
    Cell Significance Index: -7.2800
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.2306
    Cell Significance Index: -1.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** IGHMBP2 is a unique gene that exhibits a wide range of expression patterns across different cell types. It is significantly expressed in germ cells, cerebral cortex GABAergic interneurons, forebrain radial glial cells, absorptive cells, intestinal crypt stem cells, tuft cells of the colon, cardiac muscle myoblasts, BEST4+ intestinal epithelial cells, and human cells in general. This widespread expression suggests that IGHMBP2 may play a pivotal role in the development and maintenance of various tissues and organs. **Pathways and Functions:** IGHMBP2 is involved in several critical pathways, including: 1. **5'-3' DNA helicase activity:** IGHMBP2 exhibits 5'-3' DNA helicase activity, which is essential for unwinding double-stranded DNA and facilitating DNA replication and repair processes. 2. **5'-3' RNA helicase activity:** This activity is crucial for unwinding single-stranded RNA, which is necessary for RNA processing, splicing, and translation. 3. **ATP-dependent activity:** IGHMBP2 requires ATP hydrolysis to perform its functions, highlighting its dependence on energy sources for DNA and RNA processes. 4. **DNA binding and duplex unwinding:** IGHMBP2 binds to DNA and unwinds double-stranded DNA, which is essential for transcription factor binding, gene expression regulation, and DNA repair. 5. **RNA binding and secondary structure unwinding:** IGHMBP2 binds to RNA and unwinds single-stranded RNA, facilitating RNA processing, splicing, and translation. **Clinical Significance:** IGHMBP2 has significant implications for various diseases and disorders, including: 1. **Cancer:** Alterations in IGHMBP2 expression have been observed in various types of cancer, including leukemia, lymphoma, and breast cancer. IGHMBP2 may play a role in cancer development and progression. 2. **Neurological disorders:** IGHMBP2 is expressed in GABAergic interneurons, which are involved in neurological disorders such as epilepsy and Parkinson's disease. Alterations in IGHMBP2 expression may contribute to these disorders. 3. **Immunological disorders:** IGHMBP2 may play a role in regulating immune responses, and alterations in its expression may contribute to immunological disorders such as autoimmune diseases and immunodeficiency. In conclusion, IGHMBP2 is a multifaceted gene that plays a crucial role in regulating DNA and RNA processes across various cell types. Its widespread expression and involvement in critical pathways make it a valuable target for understanding disease mechanisms and developing novel therapeutic strategies. Further research is necessary to fully elucidate the functions and clinical significance of IGHMBP2, but its potential implications for human health and disease are undeniable.

Genular Protein ID: 327896400

Symbol: SMBP2_HUMAN

Name: DNA-binding protein SMUBP-2

UniProtKB Accession Codes:

P38935 A0PJD2 Q00443 Q14177

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEBI 22 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 27 Gene3D 4 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 Rhea 4 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8349627

Title: The human S mu bp-2, a DNA-binding protein specific to the single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.

PubMed ID: 8349627

DOI: 10.1016/s0021-9258(19)85357-7

PubMed ID: 10049831

Title: Smubp-2 represses the Epstein-Barr virus lytic switch promoter.

PubMed ID: 10049831

DOI: 10.1006/viro.1998.9588

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1714899

Title: A recombinant cDNA derived from human brain encodes a DNA binding protein that stimulates transcription of the human neurotropic virus JCV.

PubMed ID: 1714899

DOI: 10.1016/s0021-9258(18)98490-5

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19158098

Title: IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1).

PubMed ID: 19158098

DOI: 10.1093/hmg/ddp028

PubMed ID: 19299493

Title: Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.

PubMed ID: 19299493

DOI: 10.1093/hmg/ddp134

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 30218034

Title: UPF1-like helicase grip on nucleic acids dictates processivity.

PubMed ID: 30218034

DOI: 10.1038/s41467-018-06313-y

PubMed ID: 12547203

Title: Solution structure of the R3H domain from human Smubp-2.

PubMed ID: 12547203

DOI: 10.1016/s0022-2836(02)01381-5

PubMed ID: 22999958

Title: Structural basis for 5'-end-specific recognition of single-stranded DNA by the R3H domain from human Smubp-2.

PubMed ID: 22999958

DOI: 10.1016/j.jmb.2012.09.010

PubMed ID: 22965130

Title: The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1.

PubMed ID: 22965130

DOI: 10.1093/nar/gks792

PubMed ID: 11528396

Title: Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1.

PubMed ID: 11528396

DOI: 10.1038/ng703

PubMed ID: 14681881

Title: Infantile spinal muscular atrophy with respiratory distress type 1 (SMARD1).

PubMed ID: 14681881

DOI: 10.1002/ana.10755

PubMed ID: 15290238

Title: Genomic rearrangements at the IGHMBP2 gene locus in two patients with SMARD1.

PubMed ID: 15290238

DOI: 10.1007/s00439-004-1156-0

PubMed ID: 15108294

Title: Allelic heterogeneity of SMARD1 at the IGHMBP2 locus.

PubMed ID: 15108294

DOI: 10.1002/humu.9241

PubMed ID: 15797190

Title: A new mutation of IGHMBP2 gene in spinal muscular atrophy with respiratory distress type 1.

PubMed ID: 15797190

DOI: 10.1016/j.pediatrneurol.2004.11.003

PubMed ID: 17431882

Title: Clinical and mutational profile in spinal muscular atrophy with respiratory distress (SMARD): defining novel phenotypes through hierarchical cluster analysis.

PubMed ID: 17431882

DOI: 10.1002/humu.20525

PubMed ID: 18802676

Title: Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.

PubMed ID: 18802676

DOI: 10.1007/s00109-008-0402-7

PubMed ID: 25439726

Title: Truncating and missense mutations in IGHMBP2 cause Charcot-Marie Tooth disease type 2.

PubMed ID: 25439726

DOI: 10.1016/j.ajhg.2014.10.002

Sequence Information:

  • Length: 993
  • Mass: 109149
  • Checksum: DE785579EE60E26F
  • Sequence:
    • MASAAVESFV TKQLDLLELE RDAEVEERRS WQENISLKEL QSRGVCLLKL QVSSQRTGLY 
GRLLVTFEPR RYGSAAALPS NSFTSGDIVG LYDAANEGSQ LATGILTRVT QKSVTVAFDE 
SHDFQLSLDR ENSYRLLKLA NDVTYRRLKK ALIALKKYHS GPASSLIEVL FGRSAPSPAS 
EIHPLTFFNT CLDTSQKEAV LFALSQKELA IIHGPPGTGK TTTVVEIILQ AVKQGLKVLC 
CAPSNIAVDN LVERLALCKQ RILRLGHPAR LLESIQQHSL DAVLARSDSA QIVADIRKDI 
DQVFVKNKKT QDKREKSNFR NEIKLLRKEL KEREEAAMLE SLTSANVVLA TNTGASADGP 
LKLLPESYFD VVVIDECAQA LEASCWIPLL KARKCILAGD HKQLPPTTVS HKAALAGLSL 
SLMERLAEEY GARVVRTLTV QYRMHQAIMR WASDTMYLGQ LTAHSSVARH LLRDLPGVAA 
TEETGVPLLL VDTAGCGLFE LEEEDEQSKG NPGEVRLVSL HIQALVDAGV PARDIAVVSP 
YNLQVDLLRQ SLVHRHPELE IKSVDGFQGR EKEAVILSFV RSNRKGEVGF LAEDRRINVA 
VTRARRHVAV ICDSRTVNNH AFLKTLVEYF TQHGEVRTAF EYLDDIVPEN YSHENSQGSS 
HAATKPQGPA TSTRTGSQRQ EGGQEAAAPA RQGRKKPAGK SLASEAPSQP SLNGGSPEGV 
ESQDGVDHFR AMIVEFMASK KMQLEFPPSL NSHDRLRVHQ IAEEHGLRHD SSGEGKRRFI 
TVSKRAPRPR AALGPPAGTG GPAPLQPVPP TPAQTEQPPR EQRGPDQPDL RTLHLERLQR 
VRSAQGQPAS KEQQASGQQK LPEKKKKKAK GHPATDLPTE EDFEALVSAA VKADNTCGFA 
KCTAGVTTLG QFCQLCSRRY CLSHHLPEIH GCGERARAHA RQRISREGVL YAGSGTKNGS 
LDPAKRAQLQ RRLDKKLSEL SNQRTSRRKE RGT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.