Details for: IL1R1

Gene ID: 3554

Symbol: IL1R1

Ensembl ID: ENSG00000115594

Description: interleukin 1 receptor type 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 191.6484
    Cell Significance Index: -29.8100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 118.2369
    Cell Significance Index: -29.9900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 58.9465
    Cell Significance Index: -27.8300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 58.1651
    Cell Significance Index: -23.6300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 24.0641
    Cell Significance Index: -29.6700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.5176
    Cell Significance Index: -29.6700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.3700
    Cell Significance Index: -16.1300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 6.5015
    Cell Significance Index: 186.3700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.9158
    Cell Significance Index: -18.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 3.6479
    Cell Significance Index: 84.2800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 3.0866
    Cell Significance Index: 189.2400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.3933
    Cell Significance Index: 51.8500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.9474
    Cell Significance Index: 30.1300
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.6315
    Cell Significance Index: 12.8800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.5352
    Cell Significance Index: 25.8600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4648
    Cell Significance Index: 290.7000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.3696
    Cell Significance Index: 8.5100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 1.3529
    Cell Significance Index: 33.0100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.3127
    Cell Significance Index: 25.6200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.2447
    Cell Significance Index: 22.0000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1570
    Cell Significance Index: 220.1800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1513
    Cell Significance Index: 628.7700
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.0952
    Cell Significance Index: 3.8100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.0085
    Cell Significance Index: 129.2800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9811
    Cell Significance Index: 97.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.9286
    Cell Significance Index: 589.7800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.9119
    Cell Significance Index: 24.8200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.8781
    Cell Significance Index: 12.6300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.8723
    Cell Significance Index: 9.9100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.8518
    Cell Significance Index: 21.9000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.8275
    Cell Significance Index: 7.6200
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.7682
    Cell Significance Index: 7.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5091
    Cell Significance Index: 459.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.4734
    Cell Significance Index: 23.9200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3525
    Cell Significance Index: 16.4400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3446
    Cell Significance Index: 152.3700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3368
    Cell Significance Index: 54.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3053
    Cell Significance Index: 41.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2069
    Cell Significance Index: 22.5100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2043
    Cell Significance Index: 14.4500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1745
    Cell Significance Index: 31.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1559
    Cell Significance Index: 17.8700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1482
    Cell Significance Index: 279.1300
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.1329
    Cell Significance Index: 1.1300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0827
    Cell Significance Index: 10.1700
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.0802
    Cell Significance Index: 0.8500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0502
    Cell Significance Index: 34.7000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0479
    Cell Significance Index: 2.1700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0266
    Cell Significance Index: 12.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0255
    Cell Significance Index: 4.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0193
    Cell Significance Index: 2.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0159
    Cell Significance Index: 12.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0153
    Cell Significance Index: 28.2600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0113
    Cell Significance Index: 0.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0091
    Cell Significance Index: 0.6300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0087
    Cell Significance Index: 0.5200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0061
    Cell Significance Index: 9.3500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0102
    Cell Significance Index: -0.3600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0104
    Cell Significance Index: -7.7100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0179
    Cell Significance Index: -11.2000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0185
    Cell Significance Index: -13.5800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0211
    Cell Significance Index: -28.6400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0219
    Cell Significance Index: -0.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0226
    Cell Significance Index: -12.7200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0280
    Cell Significance Index: -0.7000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0307
    Cell Significance Index: -2.3600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0580
    Cell Significance Index: -20.8000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0624
    Cell Significance Index: -4.6500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0722
    Cell Significance Index: -10.5000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0793
    Cell Significance Index: -1.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0823
    Cell Significance Index: -23.6900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0827
    Cell Significance Index: -17.4100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0911
    Cell Significance Index: -4.2800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0963
    Cell Significance Index: -19.3200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1107
    Cell Significance Index: -1.5100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1261
    Cell Significance Index: -16.2900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1465
    Cell Significance Index: -7.6100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1691
    Cell Significance Index: -8.8100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1759
    Cell Significance Index: -17.9700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1775
    Cell Significance Index: -20.2600
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.1906
    Cell Significance Index: -0.8800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2357
    Cell Significance Index: -27.8000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2535
    Cell Significance Index: -26.4000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2609
    Cell Significance Index: -7.2900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3028
    Cell Significance Index: -23.9900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3167
    Cell Significance Index: -6.5700
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.3801
    Cell Significance Index: -6.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4244
    Cell Significance Index: -28.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4252
    Cell Significance Index: -27.4300
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.4557
    Cell Significance Index: -2.1800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4559
    Cell Significance Index: -7.6300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4706
    Cell Significance Index: -29.6600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4760
    Cell Significance Index: -29.2600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5083
    Cell Significance Index: -7.3000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5155
    Cell Significance Index: -18.9300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5317
    Cell Significance Index: -13.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5603
    Cell Significance Index: -31.4400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5810
    Cell Significance Index: -3.5100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5833
    Cell Significance Index: -8.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IL1R1 is a type I interleukin receptor, characterized by its ability to bind to interleukin-1 (IL-1), a pro-inflammatory cytokine that plays a central role in the regulation of immune responses. The IL1R1 receptor is composed of two subunits: a ligand-binding subunit (IL1R1) and an intracellular signaling subunit (IL1R1-IL1R1). Upon binding to IL-1, the receptor undergoes dimerization, triggering a series of signaling events that ultimately lead to the activation of downstream transcription factors and the production of pro-inflammatory cytokines. **Pathways and Functions** The IL1R1 receptor is involved in multiple signaling pathways, including: 1. **Cytokine signaling pathway**: IL1R1 mediates the binding of IL-1 to its receptor, triggering a cascade of signaling events that activate transcription factors, such as NF-κB and AP-1, leading to the expression of pro-inflammatory cytokines. 2. **Inflammatory response pathway**: IL1R1 plays a critical role in the regulation of inflammatory responses, including the production of pro-inflammatory cytokines, chemokines, and other inflammatory mediators. 3. **Immune response pathway**: IL1R1 is involved in the activation of immune cells, such as macrophages and T cells, leading to the production of cytokines and the activation of immune responses. **Clinical Significance** The dysregulation of IL1R1 has been implicated in various diseases, including: 1. **Inflammatory disorders**: IL1R1 has been implicated in the pathogenesis of inflammatory disorders, such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. 2. **Neurological disorders**: IL1R1 has been implicated in the pathogenesis of neurological disorders, such as multiple sclerosis and Alzheimer's disease. 3. **Cancer**: IL1R1 has been implicated in the progression of various cancers, including breast, lung, and colon cancer. 4. **SARS-CoV infections**: IL1R1 has been implicated in the pathogenesis of SARS-CoV infections, highlighting its potential as a therapeutic target for the treatment of COVID-19. In conclusion, the IL1R1 gene plays a critical role in the regulation of immune responses and inflammation. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the molecular mechanisms underlying IL1R1-mediated signaling pathways. Further research is needed to fully elucidate the role of IL1R1 in immune homeostasis and its potential as a therapeutic target for the treatment of various diseases.

Genular Protein ID: 3358848327

Symbol: IL1R1_HUMAN

Name: Interleukin-1 receptor type 1

UniProtKB Accession Codes:

P14778 Q587I7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 ComplexPortal 7 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EC 1 EMBL 8 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 3 RefSeq 16 Rhea 2 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2532321

Title: Sequence of the cDNA for the human fibroblast type interleukin-1 receptor.

PubMed ID: 2532321

DOI: 10.1093/nar/17.23.10114

PubMed ID: 2530587

Title: Cloning the interleukin 1 receptor from human T cells.

PubMed ID: 2530587

DOI: 10.1073/pnas.86.22.8946

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2950091

Title: The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.

PubMed ID: 2950091

DOI: 10.1016/s0021-9258(18)61450-4

PubMed ID: 8142597

Title: Specific binding of interleukin 1 (IL-1) beta and IL-1 receptor antagonist (IL-1ra) to human serum. High-affinity binding of IL-1ra to soluble IL-1 receptor type I.

PubMed ID: 8142597

DOI: 10.1016/1043-4666(93)90032-z

PubMed ID: 7989776

Title: Elevated levels of shed type II IL-1 receptor in sepsis. Potential role for type II receptor in regulation of IL-1 responses.

PubMed ID: 7989776

PubMed ID: 9371760

Title: Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein.

PubMed ID: 9371760

DOI: 10.1073/pnas.94.24.12829

PubMed ID: 9821957

Title: Phosphatidylinositol 3-kinase is recruited to a specific site in the activated IL-1 receptor I.

PubMed ID: 9821957

DOI: 10.1016/s0014-5793(98)01270-8

PubMed ID: 10653850

Title: IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells.

PubMed ID: 10653850

DOI: 10.1093/intimm/12.2.151

PubMed ID: 10671496

Title: Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways.

PubMed ID: 10671496

DOI: 10.1074/jbc.275.7.4670

PubMed ID: 9062193

Title: Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.

PubMed ID: 9062193

DOI: 10.1038/386190a0

PubMed ID: 9062194

Title: A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.

PubMed ID: 9062194

DOI: 10.1038/386194a0

PubMed ID: 10903327

Title: X-ray crystal structure of a small antagonist peptide bound to interleukin-1 receptor type 1.

PubMed ID: 10903327

DOI: 10.1074/jbc.m006071200

PubMed ID: 37315560

Title: Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design.

PubMed ID: 37315560

DOI: 10.1016/j.immuni.2023.05.014

Sequence Information:

  • Length: 569
  • Mass: 65402
  • Checksum: 5BAA83F8F0225C25
  • Sequence:
    • MKVLLRLICF IALLISSLEA DKCKEREEKI ILVSSANEID VRPCPLNPNE HKGTITWYKD 
DSKTPVSTEQ ASRIHQHKEK LWFVPAKVED SGHYYCVVRN SSYCLRIKIS AKFVENEPNL 
CYNAQAIFKQ KLPVAGDGGL VCPYMEFFKN ENNELPKLQW YKDCKPLLLD NIHFSGVKDR 
LIVMNVAEKH RGNYTCHASY TYLGKQYPIT RVIEFITLEE NKPTRPVIVS PANETMEVDL 
GSQIQLICNV TGQLSDIAYW KWNGSVIDED DPVLGEDYYS VENPANKRRS TLITVLNISE 
IESRFYKHPF TCFAKNTHGI DAAYIQLIYP VTNFQKHMIG ICVTLTVIIV CSVFIYKIFK 
IDIVLWYRDS CYDFLPIKAS DGKTYDAYIL YPKTVGEGST SDCDIFVFKV LPEVLEKQCG 
YKLFIYGRDD YVGEDIVEVI NENVKKSRRL IIILVRETSG FSWLGGSSEE QIAMYNALVQ 
DGIKVVLLEL EKIQDYEKMP ESIKFIKQKH GAIRWSGDFT QGPQSAKTRF WKNVRYHMPV 
QRRSPSSKHQ LLSPATKEKL QREAHVPLG

Genular Protein ID: 582624846

Symbol: B8ZZW4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B8ZZW4

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 10 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 4 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 538
  • Mass: 62029
  • Checksum: DDBACC413E9618E5
  • Sequence:
    • MKVLLRLICF IALLISSLEA DKCKEREEKI ILVSSANEID VRPCPLNPNE HKGTITWYKD 
DSKTPVSTEQ ASRIHQHKEK LWFVPAKVED SGHYYCVVRN SSYCLRIKIS AKFVENEPNL 
CYNAQAIFKQ KLPVAGDGGL VCPYMEFFKN ENNELPKLQW YKDCKPLLLD NIHFSGVKDR 
LIVMNVAEKH RGNYTCHASY TYLGKQYPIT RVIEFITLEE NKPTRPVIVS PANETMEVDL 
GSQIQLICNV TGQLSDIAYW KWNGSVIDED DPVLGEDYYS VENPANKRRS TLITVLNISE 
IESRFYKHPF TCFAKNTHGI DAAYIQLIYP VTNFQKHMIG ICVTLTVIIV CSVFIYKIFK 
IDIVLWYRDS CYDFLPIKVL PEVLEKQCGY KLFIYGRDDY VGEDIVEVIN ENVKKSRRLI 
IILVRETSGF SWLGGSSEEQ IAMYNALVQD GIKVVLLELE KIQDYEKMPE SIKFIKQKHG 
AIRWSGDFTQ GPQSAKTRFW KNVRYHMPVQ RRSPSSKHQL LSPATKEKLQ REAHVPLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.