Details for: ING1

Gene ID: 3621

Symbol: ING1

Ensembl ID: ENSG00000153487

Description: inhibitor of growth family member 1

Associated with

  • Metal ion binding
    (GO:0046872)
  • Methylated histone binding
    (GO:0035064)
  • Negative regulation of cell growth
    (GO:0030308)
  • Negative regulation of cell migration
    (GO:0030336)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of stem cell population maintenance
    (GO:1902455)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Negative regulation of transforming growth factor beta receptor signaling pathway
    (GO:0030512)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of stem cell population maintenance
    (GO:1902459)
  • Protein binding
    (GO:0005515)
  • Protein import into nucleus
    (GO:0006606)
  • Regulation of programmed cell death
    (GO:0043067)
  • Sin3-type complex
    (GO:0070822)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 127.4870
    Cell Significance Index: -19.8300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 46.4976
    Cell Significance Index: -18.8900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 46.4074
    Cell Significance Index: -21.9100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 41.8558
    Cell Significance Index: -21.5300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 19.8273
    Cell Significance Index: -18.9300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.3486
    Cell Significance Index: -21.3900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.2344
    Cell Significance Index: -19.3800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.4890
    Cell Significance Index: -21.6600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.5744
    Cell Significance Index: -14.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.7142
    Cell Significance Index: 77.7000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.1915
    Cell Significance Index: 34.3300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9924
    Cell Significance Index: 59.5800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9345
    Cell Significance Index: 101.6400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.8931
    Cell Significance Index: 25.6000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8349
    Cell Significance Index: 43.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7840
    Cell Significance Index: 107.6700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7728
    Cell Significance Index: 125.6900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7592
    Cell Significance Index: 97.3300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7159
    Cell Significance Index: 15.5100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.6701
    Cell Significance Index: 17.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6680
    Cell Significance Index: 127.1300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6325
    Cell Significance Index: 8.6300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5669
    Cell Significance Index: 36.5800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.5179
    Cell Significance Index: 10.8400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5106
    Cell Significance Index: 278.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5023
    Cell Significance Index: 453.5000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4909
    Cell Significance Index: 33.9500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4463
    Cell Significance Index: 197.3200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4377
    Cell Significance Index: 43.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4208
    Cell Significance Index: 51.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4180
    Cell Significance Index: 75.3500
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.3275
    Cell Significance Index: 3.4800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3258
    Cell Significance Index: 15.1900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3207
    Cell Significance Index: 22.6800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2966
    Cell Significance Index: 13.9400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2873
    Cell Significance Index: 7.8200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.2667
    Cell Significance Index: 2.2400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2581
    Cell Significance Index: 16.2700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2398
    Cell Significance Index: 48.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.2194
    Cell Significance Index: 7.6200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2075
    Cell Significance Index: 7.2900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1856
    Cell Significance Index: 4.6400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1760
    Cell Significance Index: 3.6500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1661
    Cell Significance Index: 2.7800
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.0902
    Cell Significance Index: 0.5300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0800
    Cell Significance Index: 2.1400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.0616
    Cell Significance Index: 0.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0600
    Cell Significance Index: 7.7500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0566
    Cell Significance Index: 20.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0551
    Cell Significance Index: 10.9300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0484
    Cell Significance Index: 1.0300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0482
    Cell Significance Index: 5.6900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.0390
    Cell Significance Index: 0.5000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0191
    Cell Significance Index: 1.4200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0067
    Cell Significance Index: 0.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0044
    Cell Significance Index: -8.3400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0050
    Cell Significance Index: -7.7700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0085
    Cell Significance Index: -5.8600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0094
    Cell Significance Index: -17.3700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0123
    Cell Significance Index: -16.7600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0149
    Cell Significance Index: -10.9000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0175
    Cell Significance Index: -13.2100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0226
    Cell Significance Index: -2.3100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0244
    Cell Significance Index: -15.4900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0283
    Cell Significance Index: -20.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0351
    Cell Significance Index: -19.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0357
    Cell Significance Index: -16.2200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0387
    Cell Significance Index: -0.4400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0419
    Cell Significance Index: -26.1400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0442
    Cell Significance Index: -2.3200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0453
    Cell Significance Index: -0.8000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0462
    Cell Significance Index: -1.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0492
    Cell Significance Index: -14.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0532
    Cell Significance Index: -9.0900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0715
    Cell Significance Index: -8.3300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0715
    Cell Significance Index: -4.0100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0768
    Cell Significance Index: -4.7200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0905
    Cell Significance Index: -13.1600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1095
    Cell Significance Index: -2.5300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1148
    Cell Significance Index: -24.1700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1159
    Cell Significance Index: -3.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1172
    Cell Significance Index: -13.4300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1708
    Cell Significance Index: -2.5600
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.1947
    Cell Significance Index: -1.2100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2030
    Cell Significance Index: -21.1400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2135
    Cell Significance Index: -16.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2288
    Cell Significance Index: -14.0300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2388
    Cell Significance Index: -18.9100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2416
    Cell Significance Index: -2.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2417
    Cell Significance Index: -16.2500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2560
    Cell Significance Index: -2.6500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2564
    Cell Significance Index: -11.3400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2832
    Cell Significance Index: -14.7500
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.2902
    Cell Significance Index: -3.0300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2916
    Cell Significance Index: -5.3900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2926
    Cell Significance Index: -4.1900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2931
    Cell Significance Index: -2.3900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3191
    Cell Significance Index: -16.1300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3325
    Cell Significance Index: -13.6200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3528
    Cell Significance Index: -13.3600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ING1 is a member of the inhibitor of growth family, which consists of a group of proteins that regulate cell growth and proliferation. The ING1 protein is a nuclear protein that binds to specific DNA sequences, thereby inhibiting the expression of genes involved in cell growth and migration. ING1 is highly expressed in various cell types, including glandular epithelial cells, immune cells, and stem cells. **Pathways and Functions:** ING1 is involved in multiple signaling pathways that regulate cell growth, migration, and transcription. Some of the key pathways include: 1. **Negative regulation of cell growth:** ING1 inhibits the expression of genes involved in cell growth and proliferation, thereby regulating cell growth and preventing uncontrolled cell division. 2. **Negative regulation of cell migration:** ING1 inhibits the expression of genes involved in cell migration, thereby regulating cell migration and preventing uncontrolled cell movement. 3. **Negative regulation of transcription by RNA polymerase II:** ING1 inhibits the expression of genes involved in transcription by RNA polymerase II, thereby regulating gene expression and preventing uncontrolled transcription. 4. **Positive regulation of DNA-templated transcription:** ING1 activates the expression of genes involved in transcription, thereby regulating gene expression and promoting cell growth and differentiation. **Clinical Significance:** ING1 has been implicated in various diseases, including: 1. **Cancer:** ING1 is often downregulated in cancer cells, leading to uncontrolled cell growth and tumor formation. 2. **Autoimmune diseases:** ING1 has been shown to regulate immune cell function and prevent autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 3. **Cardiovascular disease:** ING1 has been implicated in the regulation of cardiac function and the prevention of cardiovascular disease. 4. **Neurological disorders:** ING1 has been shown to regulate neuronal function and the prevention of neurological disorders, such as Alzheimer's disease and Parkinson's disease. **Conclusion:** ING1 is a multifaceted gene that plays a crucial role in regulating various cellular processes, including cell growth, migration, and transcription. Its dysregulation has been implicated in various diseases, including cancer, autoimmune diseases, cardiovascular disease, and neurological disorders. Further research is needed to fully understand the role of ING1 in human health and disease, and to develop therapeutic strategies that target this gene. **Implications for Immunology:** ING1 has significant implications for immunology, as it regulates immune cell function and prevents autoimmune diseases. Understanding the role of ING1 in immune cell function and autoimmune disease can lead to the development of new therapeutic strategies for the treatment of autoimmune diseases. Additionally, ING1's role in regulating stem cell function and preventing cancer can lead to the development of new therapies for cancer treatment. **Future Directions:** Future research should focus on the following areas: 1. **Understanding the mechanisms of ING1 regulation:** Further research is needed to understand how ING1 is regulated at the transcriptional and post-transcriptional levels. 2. **Investigating the role of ING1 in different diseases:** ING1's role in different diseases, including cancer, autoimmune diseases, cardiovascular disease, and neurological disorders, should be further investigated. 3. **Developing therapeutic strategies:** Therapeutic strategies that target ING1 should be developed to treat diseases where ING1 is dysregulated. In conclusion, ING1 is a multifaceted gene that plays a crucial role in regulating various cellular processes, including cell growth, migration, and transcription. Its dysregulation has been implicated in various diseases, and further research is needed to fully understand its role in human health and disease.

Genular Protein ID: 1079695373

Symbol: ING1_HUMAN

Name: Inhibitor of growth protein 1

UniProtKB Accession Codes:

Q9UK53 O00532 O43658 Q53ZR3 Q5T9G8 Q5T9G9 Q5T9H0 Q5T9H1 Q9H007 Q9HD98 Q9HD99 Q9NS83 Q9P0U6 Q9UBC6 Q9UIJ1 Q9UIJ2 Q9UIJ3 Q9UIJ4 Q9UK52

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CTD 1 ChEBI 8 ChiTaRS 1 ComplexPortal 3 DIP 3 DMDM 1 DNASU 1 DisGeNET 1 EMBL 32 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 7 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8944021

Title: Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation.

PubMed ID: 8944021

DOI: 10.1038/ng1296-415

PubMed ID: 10626813

Title: Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene.

PubMed ID: 10626813

PubMed ID: 10779953

Title: Genomic organization of the suppressor gene for tumor growth ING1.

PubMed ID: 10779953

PubMed ID: 10866301

Title: Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas.

PubMed ID: 10866301

PubMed ID: 10807544

Title: p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1.

PubMed ID: 10807544

DOI: 10.1007/s100380050206

PubMed ID: 11481424

Title: DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53.

PubMed ID: 11481424

DOI: 10.1073/pnas.161151798

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9440695

Title: The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control.

PubMed ID: 9440695

DOI: 10.1038/34675

PubMed ID: 16728974

Title: ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

PubMed ID: 16728974

DOI: 10.1038/nature04835

PubMed ID: 22419112

Title: Nucleolar protein CSIG is required for p33ING1 function in UV-induced apoptosis.

PubMed ID: 22419112

DOI: 10.1038/cddis.2012.22

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 18533182

Title: Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.

PubMed ID: 18533182

DOI: 10.1016/j.jmb.2008.04.061

Sequence Information:

  • Length: 422
  • Mass: 46738
  • Checksum: 03D6AEEAA6E39090
  • Sequence:
    • MSFVECPYHS PAERLVAEAD EGGPSAITGM GLCFRCLLFS FSGRSGVEGG RVDLNVFGSL 
GLQPWIGSSR CWGGPCSSAL RCGWFSSWPP PSKSAIPIGG GSRGAGRVSR WPPPHWLEAW 
RVSPLPLSPL SPATFGRGFI AVAVIPGLWA RGRGCSSDRL PRPAGPARRQ FQAASLLTRG 
WGRAWPWKQI LKELDECYER FSRETDGAQK RRMLHCVQRA LIRSQELGDE KIQIVSQMVE 
LVENRTRQVD SHVELFEAQQ ELGDTAGNSG KAGADRPKGE AAAQADKPNS KRSRRQRNNE 
NRENASSNHD HDDGASGTPK EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ 
VSYGEMIGCD NDECPIEWFH FSCVGLNHKP KGKWYCPKCR GENEKTMDKA LEKSKKERAY 
NR

Genular Protein ID: 2879243553

Symbol: A0A0C4DFW2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DFW2

Database IDs:

ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 8 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 4 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 422
  • Mass: 46781
  • Checksum: 606EC90D3EF324C1
  • Sequence:
    • MSFVECPYHS PAERLVAEAD EGGPSAITGM GLCFRCLLFS FSGRSGVEGG RVDLNVFGSL 
GLQPWIGSSR CWGGPCSSAL RCGWFSSWPP PSKSAIPIGG GSRGAGRVSR WPPPHWLEAW 
RVSPRPLSPL SPATFGRGFI AVAVIPGLWA RGRGCSSDRL PRPAGPARRQ FQAASLLTRG 
WGRAWPWKQI LKELDECYER FSRETDGAQK RRMLHCVQRA LIRSQELGDE KIQIVSQMVE 
LVENRTRQVD SHVELFEAQQ ELGDTAGNSG KAGADRPKGE AAAQADKPNS KRSRRQRNNE 
NRENASSNHD HDDGASGTPK EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ 
VSYGEMIGCD NDECPIEWFH FSCVGLNHKP KGKWYCPKCR GENEKTMDKA LEKSKKERAY 
NR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.