Details for: INSIG1

Gene ID: 3638

Symbol: INSIG1

Ensembl ID: ENSG00000186480

Description: insulin induced gene 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 288.0834
    Cell Significance Index: -44.8100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 174.6941
    Cell Significance Index: -44.3100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 118.0004
    Cell Significance Index: -48.6100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 89.7382
    Cell Significance Index: -46.1600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.7524
    Cell Significance Index: -47.7800
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 16.4552
    Cell Significance Index: 21.2900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.8836
    Cell Significance Index: -42.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.1767
    Cell Significance Index: -48.0500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.5743
    Cell Significance Index: -35.5500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.3877
    Cell Significance Index: -13.9800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 5.5988
    Cell Significance Index: 40.2100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 5.0721
    Cell Significance Index: 89.6300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 3.9629
    Cell Significance Index: 66.7600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.2459
    Cell Significance Index: 86.9800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.5717
    Cell Significance Index: 75.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.2977
    Cell Significance Index: 120.6400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.4217
    Cell Significance Index: 183.6700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.0227
    Cell Significance Index: 47.6900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.0070
    Cell Significance Index: 47.3300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9550
    Cell Significance Index: 862.2500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7346
    Cell Significance Index: 6.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6863
    Cell Significance Index: 19.7800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.6337
    Cell Significance Index: 108.2100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.5996
    Cell Significance Index: 8.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5986
    Cell Significance Index: 97.3600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.5777
    Cell Significance Index: 16.5600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5656
    Cell Significance Index: 29.3800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5453
    Cell Significance Index: 14.5600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5438
    Cell Significance Index: 59.1500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4730
    Cell Significance Index: 58.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4702
    Cell Significance Index: 60.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4605
    Cell Significance Index: 251.5000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4515
    Cell Significance Index: 81.3900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4297
    Cell Significance Index: 19.4800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3202
    Cell Significance Index: 19.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.3093
    Cell Significance Index: 23.0500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3066
    Cell Significance Index: 109.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2927
    Cell Significance Index: 58.7300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2909
    Cell Significance Index: 57.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2903
    Cell Significance Index: 6.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2342
    Cell Significance Index: 440.9000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2138
    Cell Significance Index: 290.7000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1928
    Cell Significance Index: 22.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1867
    Cell Significance Index: 18.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1519
    Cell Significance Index: 10.5100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1167
    Cell Significance Index: 7.5300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0999
    Cell Significance Index: 3.5100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0871
    Cell Significance Index: 65.8900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0831
    Cell Significance Index: 15.8100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0710
    Cell Significance Index: 109.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0614
    Cell Significance Index: 27.1400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0179
    Cell Significance Index: 11.3900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0143
    Cell Significance Index: 26.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0063
    Cell Significance Index: -4.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0136
    Cell Significance Index: -8.5000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0240
    Cell Significance Index: -3.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0249
    Cell Significance Index: -17.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0465
    Cell Significance Index: -4.7500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0489
    Cell Significance Index: -35.8400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0526
    Cell Significance Index: -29.6700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0672
    Cell Significance Index: -7.6700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0699
    Cell Significance Index: -3.9200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0866
    Cell Significance Index: -39.3000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1110
    Cell Significance Index: -23.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1140
    Cell Significance Index: -32.8000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.1829
    Cell Significance Index: -2.8300
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.2110
    Cell Significance Index: -2.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2250
    Cell Significance Index: -26.2300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2264
    Cell Significance Index: -25.9400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2628
    Cell Significance Index: -38.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3102
    Cell Significance Index: -10.7800
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.3108
    Cell Significance Index: -5.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3149
    Cell Significance Index: -8.8000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3200
    Cell Significance Index: -22.6300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.3288
    Cell Significance Index: -5.5300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3746
    Cell Significance Index: -9.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3818
    Cell Significance Index: -12.2300
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: -0.4074
    Cell Significance Index: -1.5600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4187
    Cell Significance Index: -43.6000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4623
    Cell Significance Index: -8.5500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5349
    Cell Significance Index: -35.9700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5484
    Cell Significance Index: -43.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6370
    Cell Significance Index: -48.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.6714
    Cell Significance Index: -41.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.6800
    Cell Significance Index: -18.5100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.6821
    Cell Significance Index: -8.4600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7167
    Cell Significance Index: -45.1700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.7362
    Cell Significance Index: -15.4100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7430
    Cell Significance Index: -12.4400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7454
    Cell Significance Index: -19.9400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7512
    Cell Significance Index: -19.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7836
    Cell Significance Index: -48.0500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.8423
    Cell Significance Index: -21.0600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.8996
    Cell Significance Index: -10.2200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.9169
    Cell Significance Index: -33.6600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.9631
    Cell Significance Index: -13.1400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.9960
    Cell Significance Index: -44.0600
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -1.0115
    Cell Significance Index: -6.2900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.0410
    Cell Significance Index: -22.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.1326
    Cell Significance Index: -32.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** INSIG1 is a transcriptional regulator that belongs to the insulin-induced gene family. It is induced by insulin and is involved in the negative regulation of various metabolic pathways. The protein is primarily localized to the endoplasmic reticulum (ER) and is involved in the sequestration of cholesterol and oxysterols. INSIG1 interacts with SREBP, a transcription factor that regulates cholesterol synthesis and uptake, thereby modulating the activity of the SREBP pathway. **Pathways and Functions:** INSIG1 is involved in the following pathways: 1. **Cellular response to insulin stimulus:** INSIG1 is induced by insulin and plays a crucial role in modulating the insulin signaling pathway. 2. **Cholesterol biosynthetic process:** INSIG1 regulates the activity of SREBP, which is essential for cholesterol synthesis. 3. **Cholesterol homeostasis:** INSIG1 helps maintain cholesterol homeostasis by regulating the expression of genes involved in cholesterol synthesis and uptake. 4. **Metabolism of lipids and steroids:** INSIG1 is involved in the negative regulation of lipid and steroid biosynthesis. 5. **Protein secretion and exit from the ER:** INSIG1 regulates the secretion of proteins from the ER and their exit from the ER. 6. **SREBP signaling pathway:** INSIG1 interacts with SREBP, modulating its activity and regulating the expression of genes involved in cholesterol synthesis and uptake. **Clinical Significance:** Dysregulation of INSIG1 has been implicated in various diseases, including: 1. **Atherosclerosis:** INSIG1 plays a crucial role in maintaining cholesterol homeostasis, and its dysregulation can contribute to the development of atherosclerosis. 2. **Metabolic disorders:** INSIG1 is involved in the regulation of lipid and steroid biosynthesis, and its dysregulation can contribute to metabolic disorders, such as obesity and diabetes. 3. **Cancer:** INSIG1 has been implicated in the regulation of cell growth and differentiation, and its dysregulation can contribute to cancer development and progression. 4. **Neurological disorders:** INSIG1 is expressed in neurons and is involved in the regulation of cholesterol homeostasis, and its dysregulation can contribute to neurological disorders, such as Alzheimer's disease. In conclusion, INSIG1 is a critical regulator of cholesterol homeostasis and metabolic pathways. Its dysregulation can contribute to various diseases, highlighting the importance of understanding its mechanisms of action and its role in maintaining tissue homeostasis.

Genular Protein ID: 749189692

Symbol: INSI1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9268630

Title: Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene.

PubMed ID: 9268630

DOI: 10.1006/geno.1997.4821

PubMed ID: 12202038

Title: Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.

PubMed ID: 12202038

DOI: 10.1016/s0092-8674(02)00872-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12535518

Title: Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain.

PubMed ID: 12535518

DOI: 10.1016/s1097-2765(02)00822-5

PubMed ID: 14660594

Title: Membrane topology of human insig-1, a protein regulator of lipid synthesis.

PubMed ID: 14660594

DOI: 10.1074/jbc.m312623200

PubMed ID: 15899885

Title: Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.

PubMed ID: 15899885

DOI: 10.1074/jbc.m504041200

PubMed ID: 16168377

Title: Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.

PubMed ID: 16168377

DOI: 10.1016/j.molcel.2005.08.009

PubMed ID: 16399501

Title: Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.

PubMed ID: 16399501

DOI: 10.1016/j.cmet.2005.11.014

PubMed ID: 17043353

Title: Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.

PubMed ID: 17043353

DOI: 10.1074/jbc.m608999200

PubMed ID: 16606821

Title: Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis.

PubMed ID: 16606821

DOI: 10.1073/pnas.0601923103

PubMed ID: 20068067

Title: The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways.

PubMed ID: 20068067

DOI: 10.1158/1541-7786.mcr-08-0491

PubMed ID: 22143767

Title: Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.

PubMed ID: 22143767

DOI: 10.1073/pnas.1112831108

PubMed ID: 28604676

Title: Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

PubMed ID: 28604676

DOI: 10.1038/ncb3551

PubMed ID: 29184177

Title: Corrigendum: Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

PubMed ID: 29184177

DOI: 10.1038/ncb3651

PubMed ID: 28849786

Title: SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.

PubMed ID: 28849786

DOI: 10.1038/nrendo.2017.91

PubMed ID: 29374057

Title: Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

PubMed ID: 29374057

DOI: 10.1074/jbc.ra117.001260

PubMed ID: 32322062

Title: The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.

PubMed ID: 32322062

DOI: 10.1038/s41586-020-2183-2

PubMed ID: 23481256

Title: Rules for the recognition of dilysine retrieval motifs by coatomer.

PubMed ID: 23481256

DOI: 10.1038/emboj.2013.41

Sequence Information:

  • Length: 277
  • Mass: 29987
  • Checksum: 198068D53C658A58
  • Sequence:
  • MPRLHDHFWS CSCAHSARRR GPPRASAAGL AAKVGEMINV SVSGPSLLAA HGAPDADPAP 
    RGRSAAMSGP EPGSPYPNTW HHRLLQRSLV LFSVGVVLAL VLNLLQIQRN VTLFPEEVIA 
    TIFSSAWWVP PCCGTAAAVV GLLYPCIDSH LGEPHKFKRE WASVMRCIAV FVGINHASAK 
    LDFANNVQLS LTLAALSLGL WWTFDRSRSG LGLGITIAFL ATLITQFLVY NGVYQYTSPD 
    FLYIRSWLPC IFFSGGVTVG NIGRQLAMGV PEKPHSD

Genular Protein ID: 2342973333

Symbol: F5H6P3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 178
  • Mass: 20370
  • Checksum: 8FD0FAD53542FE0F
  • Sequence:
  • MPRLHDHFWS CSCAHSARRR GPPRASAKLD FANNVQLSLT LAALSLGLWW TFDRSRSGLG 
    LGITIAFLAT LITQFLVYNG VYQYTSPDFL YIRSWLPCIF FSGGVTVGNI GRQLAMLIPF 
    CEELNLKTTW LFHKTRSNYR VFLKSPIVIE SSKPPILRAR KILEENLTVD YDKDYLFS

Genular Protein ID: 136794793

Symbol: A4D2M9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

Sequence Information:

  • Length: 330
  • Mass: 36452
  • Checksum: 26F51232C0875C9D
  • Sequence:
  • MPRLHDHFWS CSCAHSARRR GPPRASAAGL AAKVGEMINV SVSGPSLLAA HGAPDADPAP 
    RGRSAAMSGP EPGSPYPNTW HHRLLQRSLV LFSVGVVLAL VLNLLQIQRN VTLFPEEVIA 
    TIFSSAWWVP PCCGTAAAVV GLLYPCIDSH LGEPHKFKRE WASVMRCIAV FVGINHASAK 
    LDFANNVQLS LTLAALSLGL WWTFDRSRSG LGLGITIAFL ATLITQFLVY NGVYQYTSPD 
    FLYIRSWLPC IFFSGGVTVG NIGRQLAMLI PFCEELNLKT TWLFHKTRSN YRVFLKSPIV 
    IESSKPPILR ARKILEENLT VDYDKDYLFS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.