Details for: CD82

Gene ID: 3732

Symbol: CD82

Ensembl ID: ENSG00000085117

Description: CD82 molecule

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 4.76
    Marker Score: 3812
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.86
    Marker Score: 4138
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.55
    Marker Score: 10426
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 2.24
    Marker Score: 562.5
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 2.11
    Marker Score: 1527
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.06
    Marker Score: 13165
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.05
    Marker Score: 2160
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.04
    Marker Score: 1229
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 2.01
    Marker Score: 5108
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.01
    Marker Score: 1342
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 2
    Marker Score: 974.5
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.99
    Marker Score: 17133
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.98
    Marker Score: 634
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.97
    Marker Score: 14660
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.92
    Marker Score: 15024.5
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 1.89
    Marker Score: 1781
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.86
    Marker Score: 1990
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.77
    Marker Score: 398
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.77
    Marker Score: 1393
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.74
    Marker Score: 502
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.7
    Marker Score: 5040
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.69
    Marker Score: 598
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.67
    Marker Score: 2368
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 1.66
    Marker Score: 746
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.65
    Marker Score: 772
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 1.65
    Marker Score: 3007
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.65
    Marker Score: 576
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.64
    Marker Score: 2258
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 1.64
    Marker Score: 1231
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.63
    Marker Score: 804
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 1.62
    Marker Score: 6931
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 1.59
    Marker Score: 379
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.59
    Marker Score: 931
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.56
    Marker Score: 1181.5
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.55
    Marker Score: 626
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 1.54
    Marker Score: 20734
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.54
    Marker Score: 573
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.51
    Marker Score: 1050
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.51
    Marker Score: 9606
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.49
    Marker Score: 999
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.47
    Marker Score: 3352
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.46
    Marker Score: 12848
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 1.46
    Marker Score: 2252
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.44
    Marker Score: 2510
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 1.43
    Marker Score: 452
  • Cell Name: basophil (CL0000767)
    Fold Change: 1.4
    Marker Score: 664
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.39
    Marker Score: 1533
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 1.39
    Marker Score: 1046
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 1.39
    Marker Score: 3828
  • Cell Name: centroblast (CL0009112)
    Fold Change: 1.38
    Marker Score: 678
  • Cell Name: tracheobronchial goblet cell (CL0019003)
    Fold Change: 1.37
    Marker Score: 376
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.37
    Marker Score: 929
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.36
    Marker Score: 6671
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.36
    Marker Score: 715
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.35
    Marker Score: 3298
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.34
    Marker Score: 13285
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.33
    Marker Score: 1507
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.31
    Marker Score: 2152
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 1.31
    Marker Score: 948
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.31
    Marker Score: 20473.5
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.31
    Marker Score: 1686
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 1.3
    Marker Score: 364
  • Cell Name: club cell (CL0000158)
    Fold Change: 1.29
    Marker Score: 1510
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.28
    Marker Score: 1072
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.27
    Marker Score: 4381
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 1.27
    Marker Score: 731
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 1.27
    Marker Score: 927
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.27
    Marker Score: 1863.5
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.26
    Marker Score: 3173.5
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.24
    Marker Score: 3250
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 1.24
    Marker Score: 1029
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.23
    Marker Score: 740
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 1.22
    Marker Score: 745
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.2
    Marker Score: 2724
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.2
    Marker Score: 5737
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.18
    Marker Score: 807
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 1.18
    Marker Score: 272
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.17
    Marker Score: 13627
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 1.17
    Marker Score: 331
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 1.13
    Marker Score: 1004
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.1
    Marker Score: 354
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.09
    Marker Score: 11067
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.09
    Marker Score: 1001
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 1.09
    Marker Score: 937
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.09
    Marker Score: 1101
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.09
    Marker Score: 469
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 1.07
    Marker Score: 259
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 1.07
    Marker Score: 273
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.05
    Marker Score: 658
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.05
    Marker Score: 2476
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.05
    Marker Score: 2058
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.04
    Marker Score: 55152
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 1.04
    Marker Score: 1087
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.04
    Marker Score: 258
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 1.03
    Marker Score: 256
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 1.03
    Marker Score: 427.5
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 1.02
    Marker Score: 256
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.01
    Marker Score: 685
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1
    Marker Score: 1003.5
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71641.5

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** * CD82 is a cell surface glycoprotein that is expressed on a variety of cell types. * It is a member of the CD8 family of cell surface glycoproteins, which are involved in the regulation of cell-cell interactions and immune responses. * CD82 is expressed on a number of immune cells, including dendritic cells, macrophages, and lymphocytes. * It is a key regulator of the activation of cytotoxic T cells. **Pathways and functions:** * CD82 is involved in the regulation of cell-cell interactions. * It is expressed on a variety of immune cells, including dendritic cells, macrophages, and lymphocytes. * CD82 is a key regulator of the activation of cytotoxic T cells. * It is involved in the regulation of inflammation and immune responses. **Clinical significance:** * Mutations in the CD82 gene have been linked to a number of human diseases, including cancer and autoimmune disorders. * CD82 is a potential target for cancer immunotherapy. * Inhibition of CD82 has been shown to be effective in inhibiting cancer growth and metastasis. **Conclusion:** The CD82 molecule is a key regulator of cell-cell interactions and immune responses. It is expressed on a variety of cell types, including dendritic cells, macrophages, and lymphocytes. CD82 is a key regulator of the activation of cytotoxic T cells. Mutations in the CD82 gene have been linked to a number of human diseases, including cancer and autoimmune disorders.

Genular Protein ID: 546798646

Symbol: CD82_HUMAN

Name: CD82 antigen

UniProtKB Accession Codes:

P27701 D3DQN6 E9PC70 Q7Z2D4 Q7Z5N2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 17 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1842498

Title: A new superfamily of lymphoid and melanoma cell proteins with extensive homology to Schistosoma mansoni antigen Sm23.

PubMed ID: 1842498

DOI: 10.1002/eji.1830210219

PubMed ID: 1401919

Title: C33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1-induced syncytium formation is a member of a new family of transmembrane proteins including CD9, CD37, CD53, and CD63.

PubMed ID: 1401919

PubMed ID: 7754374

Title: KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2.

PubMed ID: 7754374

DOI: 10.1126/science.7754374

PubMed ID: 9126478

Title: Genomic organization of the human KAI1 metastasis-suppressor gene.

PubMed ID: 9126478

DOI: 10.1006/geno.1997.4618

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12750295

Title: EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells.

PubMed ID: 12750295

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 30463011

Title: A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote alpha-Toxin Cytotoxicity.

PubMed ID: 30463011

DOI: 10.1016/j.celrep.2018.10.088

Sequence Information:

  • Length: 267
  • Mass: 29626
  • Checksum: FC379855BD1CABDE
  • Sequence:
    • MGSACIKVTK YFLFLFNLIF FILGAVILGF GVWILADKSS FISVLQTSSS SLRMGAYVFI 
GVGAVTMLMG FLGCIGAVNE VRCLLGLYFA FLLLILIAQV TAGALFYFNM GKLKQEMGGI 
VTELIRDYNS SREDSLQDAW DYVQAQVKCC GWVSFYNWTD NAELMNRPEV TYPCSCEVKG 
EEDNSLSVRK GFCEAPGNRT QSGNHPEDWP VYQEGCMEKV QAWLQENLGI ILGVGVGVAI 
IELLGMVLSI CLCRHVHSED YSKVPKY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.