Details for: KCNC1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.34
Marker Score: 9687 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.17
Marker Score: 80193 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.17
Marker Score: 688 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.15
Marker Score: 42826 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.01
Marker Score: 76393 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.98
Marker Score: 29640 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.96
Marker Score: 3985 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.91
Marker Score: 7395 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.83
Marker Score: 14047 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 1.78
Marker Score: 3680 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.7
Marker Score: 2053 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.68
Marker Score: 1586.5 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.66
Marker Score: 102090 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.6
Marker Score: 1166 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.55
Marker Score: 14567 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.49
Marker Score: 2293 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.48
Marker Score: 12701 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 169092 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.43
Marker Score: 13593 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.38
Marker Score: 577 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.31
Marker Score: 1582.5 - Cell Name: neuron (CL0000540)
Fold Change: 1.1
Marker Score: 4466 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.05
Marker Score: 6956 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.04
Marker Score: 704 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 792 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71818 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48043 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 505 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.98
Marker Score: 267 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 458 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.97
Marker Score: 402 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.96
Marker Score: 1285 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5336 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.92
Marker Score: 370 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2743 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.91
Marker Score: 895 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.91
Marker Score: 5488 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.91
Marker Score: 418 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.91
Marker Score: 2588 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 322 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5284 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.85
Marker Score: 3567 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.81
Marker Score: 12733 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.81
Marker Score: 3364 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.78
Marker Score: 4187 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1261 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 706 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.76
Marker Score: 447 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 393 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 176 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.66
Marker Score: 208 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.65
Marker Score: 2720 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.64
Marker Score: 1028 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.64
Marker Score: 1211.5 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.59
Marker Score: 380 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.59
Marker Score: 199 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.56
Marker Score: 285 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.54
Marker Score: 171 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.53
Marker Score: 1238 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.52
Marker Score: 1055 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.51
Marker Score: 5282 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.49
Marker Score: 322 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.47
Marker Score: 2189 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.43
Marker Score: 174 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.41
Marker Score: 159 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.41
Marker Score: 120 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.41
Marker Score: 13861 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.41
Marker Score: 129 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: 0.39
Marker Score: 139 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.37
Marker Score: 7949 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.37
Marker Score: 620 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.36
Marker Score: 146 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.35
Marker Score: 123 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.34
Marker Score: 3468 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.33
Marker Score: 412 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.33
Marker Score: 102 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.32
Marker Score: 195 - Cell Name: glial cell (CL0000125)
Fold Change: 0.32
Marker Score: 350 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.31
Marker Score: 164 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.3
Marker Score: 305 - Cell Name: macroglial cell (CL0000126)
Fold Change: 0.3
Marker Score: 694 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.3
Marker Score: 656.5 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.28
Marker Score: 321 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.28
Marker Score: 304 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.27
Marker Score: 305.5 - Cell Name: granule cell (CL0000120)
Fold Change: 0.27
Marker Score: 2045 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.26
Marker Score: 70 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.26
Marker Score: 89 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.26
Marker Score: 1364 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.26
Marker Score: 82 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.26
Marker Score: 164 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.25
Marker Score: 121 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.25
Marker Score: 224 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.25
Marker Score: 237 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 0.25
Marker Score: 407 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.25
Marker Score: 243 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.24
Marker Score: 146
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Other Information
Genular Protein ID: 3682779263
Symbol: KCNC1_HUMAN
Name: Potassium voltage-gated channel subfamily C member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8449507
Title: Localization of a highly conserved human potassium channel gene (NGK2-KV4; KCNC1) to chromosome 11p15.
PubMed ID: 8449507
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1400413
Title: The Shaw-related potassium channel gene, Kv3.1, on human chromosome 11, encodes the type l K+ channel in T cells.
PubMed ID: 1400413
PubMed ID: 23734863
Title: Spinocerebellar ataxia-13 Kv3.3 potassium channels: arginine-to-histidine mutations affect both functional and protein expression on the cell surface.
PubMed ID: 23734863
DOI: 10.1042/bj20130034
PubMed ID: 25401298
Title: A recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy.
PubMed ID: 25401298
DOI: 10.1038/ng.3144
Sequence Information:
- Length: 511
- Mass: 57942
- Checksum: 10A93478F7120ABB
- Sequence:
MGQGDESERI VINVGGTRHQ TYRSTLRTLP GTRLAWLAEP DAHSHFDYDP RADEFFFDRH PGVFAHILNY YRTGKLHCPA DVCGPLYEEE LAFWGIDETD VEPCCWMTYR QHRDAEEALD SFGGAPLDNS ADDADADGPG DSGDGEDELE MTKRLALSDS PDGRPGGFWR RWQPRIWALF EDPYSSRYAR YVAFASLFFI LVSITTFCLE THERFNPIVN KTEIENVRNG TQVRYYREAE TEAFLTYIEG VCVVWFTFEF LMRVIFCPNK VEFIKNSLNI IDFVAILPFY LEVGLSGLSS KAAKDVLGFL RVVRFVRILR IFKLTRHFVG LRVLGHTLRA STNEFLLLII FLALGVLIFA TMIYYAERIG AQPNDPSASE HTHFKNIPIG FWWAVVTMTT LGYGDMYPQT WSGMLVGALC ALAGVLTIAM PVPVIVNNFG MYYSLAMAKQ KLPKKKKKHI PRPPQLGSPN YCKSVVNSPH HSTQSDTCPL AQEEILEINR AGRKPLRGMS I
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.