Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 61.7184
Cell Significance Index: -9.6000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 35.3646
Cell Significance Index: -8.9700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 20.8844
Cell Significance Index: -9.8600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 7.9240
Cell Significance Index: -9.7700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.2700
Cell Significance Index: -8.7600 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 2.9796
Cell Significance Index: 7.8600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 2.9007
Cell Significance Index: 83.5800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.3120
Cell Significance Index: 138.8000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.6989
Cell Significance Index: 184.7900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 1.4895
Cell Significance Index: -4.5800 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 1.2669
Cell Significance Index: 12.7800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.1963
Cell Significance Index: 237.4000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.1239
Cell Significance Index: 24.3500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.0789
Cell Significance Index: 175.4800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0223
Cell Significance Index: 923.0500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.9779
Cell Significance Index: 67.6300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5498
Cell Significance Index: 54.3900 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.4634
Cell Significance Index: 6.6400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.4351
Cell Significance Index: 7.3300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3737
Cell Significance Index: 19.6200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3727
Cell Significance Index: 70.9200 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.2812
Cell Significance Index: 4.7300 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.2142
Cell Significance Index: 1.7100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1412
Cell Significance Index: 16.4600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1366
Cell Significance Index: 27.4000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1235
Cell Significance Index: 5.7600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1222
Cell Significance Index: 84.5400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.1118
Cell Significance Index: 1.6500 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.1012
Cell Significance Index: 0.8500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0891
Cell Significance Index: 4.0400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0859
Cell Significance Index: 2.7500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0851
Cell Significance Index: 37.6200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0789
Cell Significance Index: 22.7100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0751
Cell Significance Index: 2.6400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.0726
Cell Significance Index: 5.7500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0618
Cell Significance Index: 22.1700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0313
Cell Significance Index: 17.1000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0129
Cell Significance Index: 1.6600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0066
Cell Significance Index: 4.8500 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0025
Cell Significance Index: 0.3200 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.0013
Cell Significance Index: 0.0100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0016
Cell Significance Index: -0.2800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0019
Cell Significance Index: -0.1200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0032
Cell Significance Index: -6.0100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0052
Cell Significance Index: -9.5500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0060
Cell Significance Index: -9.2100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0085
Cell Significance Index: -0.6000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0088
Cell Significance Index: -11.9500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0090
Cell Significance Index: -0.2400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0096
Cell Significance Index: -7.2900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0108
Cell Significance Index: -7.9900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0128
Cell Significance Index: -8.1500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0129
Cell Significance Index: -0.3600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0138
Cell Significance Index: -7.7700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0144
Cell Significance Index: -1.4700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0160
Cell Significance Index: -10.0100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0210
Cell Significance Index: -9.5400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0222
Cell Significance Index: -3.0500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0230
Cell Significance Index: -1.4900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0277
Cell Significance Index: -3.2700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0310
Cell Significance Index: -0.8300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0316
Cell Significance Index: -0.7900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0332
Cell Significance Index: -5.9800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0429
Cell Significance Index: -4.9100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0456
Cell Significance Index: -5.6100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0470
Cell Significance Index: -6.8300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0496
Cell Significance Index: -10.4500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0580
Cell Significance Index: -0.8300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0607
Cell Significance Index: -1.0400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0657
Cell Significance Index: -4.1400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0668
Cell Significance Index: -4.9800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0684
Cell Significance Index: -4.6000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0728
Cell Significance Index: -1.5500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0797
Cell Significance Index: -0.8300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0825
Cell Significance Index: -5.0600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0857
Cell Significance Index: -3.7900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0949
Cell Significance Index: -9.8800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1199
Cell Significance Index: -4.5400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1221
Cell Significance Index: -5.7400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1261
Cell Significance Index: -9.6800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.1290
Cell Significance Index: -1.6000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1304
Cell Significance Index: -4.5300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1326
Cell Significance Index: -2.2200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1332
Cell Significance Index: -6.9200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1390
Cell Significance Index: -2.9100 - Cell Name: medium spiny neuron (CL1001474)
Fold Change: -0.1438
Cell Significance Index: -1.9400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1508
Cell Significance Index: -8.4600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1544
Cell Significance Index: -3.9700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1594
Cell Significance Index: -4.3400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.1762
Cell Significance Index: -2.6400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1849
Cell Significance Index: -2.1000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1964
Cell Significance Index: -6.8800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2041
Cell Significance Index: -5.4700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2051
Cell Significance Index: -3.0900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2119
Cell Significance Index: -4.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2132
Cell Significance Index: -6.7900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2181
Cell Significance Index: -7.1400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2192
Cell Significance Index: -5.6000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2247
Cell Significance Index: -5.3900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2300
Cell Significance Index: -4.9700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 287416363
Symbol: KHK_HUMAN
Name: Hepatic fructokinase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7833921
Title: Molecular basis of essential fructosuria: molecular cloning and mutational analysis of human ketohexokinase (fructokinase).
PubMed ID: 7833921
DOI: 10.1093/hmg/3.9.1627
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9799106
Title: Structure and alternative splicing of the ketohexokinase gene.
PubMed ID: 9799106
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 19237742
Title: Structures of alternatively spliced isoforms of human ketohexokinase.
PubMed ID: 19237742
PubMed ID: 12941785
Title: Properties of normal and mutant recombinant human ketohexokinases and implications for the pathogenesis of essential fructosuria.
PubMed ID: 12941785
Sequence Information:
- Length: 298
- Mass: 32523
- Checksum: BE77FC325CAC5721
- Sequence:
MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTVL SLLGAPCAFM GSMAPGHVAD FLVADFRRRG VDVSQVAWQS KGDTPSSCCI INNSNGNRTI VLHDTSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV
Genular Protein ID: 4261838461
Symbol: C9JDL1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 343
- Mass: 37622
- Checksum: A4803569FCA20887
- Sequence:
MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTVL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDSFLVAD FRRRGVDVSQ VAWQSKGDTP SSCCIINNSN GNRTIVLHDT SLPDVSATDF EKVDLTQFKW IHIEGRNASE QVKMLQRIDA HNTRQPPEQK IRVSVEVEKP REELFQLFGY GDVVFVSKDV AKHLGFQSAE EALRGLYGRV RKGAVLVCAW AEEGADALGP DGKLLHSDAF PPPRVVDTLG AGDTFNASVI FSLSQGRSVQ EALRFGCQVA GKKCGLQGFD GIV
Genular Protein ID: 2529234734
Symbol: A0A140VJM6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 298
- Mass: 32730
- Checksum: 1BA47BDC60C1B89F
- Sequence:
MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTVL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDRSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.