Details for: KPNA1

Gene ID: 3836

Symbol: KPNA1

Ensembl ID: ENSG00000114030

Description: karyopherin subunit alpha 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 291.5551
    Cell Significance Index: -45.3500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 189.0055
    Cell Significance Index: -47.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 106.5401
    Cell Significance Index: -50.3000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 98.5090
    Cell Significance Index: -40.0200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 90.1853
    Cell Significance Index: -46.3900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 42.2522
    Cell Significance Index: -40.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.4442
    Cell Significance Index: -47.4000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.0632
    Cell Significance Index: -45.7100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.1631
    Cell Significance Index: -40.4300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.5442
    Cell Significance Index: -49.5000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.1709
    Cell Significance Index: -22.2600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 2.8923
    Cell Significance Index: 70.5700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.5346
    Cell Significance Index: 65.1500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.2529
    Cell Significance Index: 451.9300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.7829
    Cell Significance Index: 123.3000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6087
    Cell Significance Index: 319.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.4968
    Cell Significance Index: 83.9900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.2534
    Cell Significance Index: 96.1900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2174
    Cell Significance Index: 16.6100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0941
    Cell Significance Index: 392.4400
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.9117
    Cell Significance Index: 14.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8940
    Cell Significance Index: 97.2400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8673
    Cell Significance Index: 141.0500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7982
    Cell Significance Index: 552.0400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.7885
    Cell Significance Index: 19.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6752
    Cell Significance Index: 25.5700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.6436
    Cell Significance Index: 28.4700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6123
    Cell Significance Index: 75.2900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6078
    Cell Significance Index: 109.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6025
    Cell Significance Index: 40.5100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5654
    Cell Significance Index: 15.8000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4835
    Cell Significance Index: 29.7200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.4773
    Cell Significance Index: 12.7900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4253
    Cell Significance Index: 12.2600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4125
    Cell Significance Index: 8.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3754
    Cell Significance Index: 37.1400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.3494
    Cell Significance Index: 4.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2937
    Cell Significance Index: 160.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2897
    Cell Significance Index: 18.2600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.2810
    Cell Significance Index: 8.0200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2542
    Cell Significance Index: 5.5700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2409
    Cell Significance Index: 4.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1911
    Cell Significance Index: 294.1700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1831
    Cell Significance Index: 9.5400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1765
    Cell Significance Index: 112.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1719
    Cell Significance Index: 323.6900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1620
    Cell Significance Index: 220.2700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1555
    Cell Significance Index: 68.7700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1491
    Cell Significance Index: 274.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1444
    Cell Significance Index: 6.7900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.1404
    Cell Significance Index: 2.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1392
    Cell Significance Index: 19.1100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0950
    Cell Significance Index: 18.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0822
    Cell Significance Index: 37.3000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0579
    Cell Significance Index: 9.8800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0342
    Cell Significance Index: 1.2000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0255
    Cell Significance Index: 3.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0016
    Cell Significance Index: 0.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0026
    Cell Significance Index: -0.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0182
    Cell Significance Index: -13.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0182
    Cell Significance Index: -11.4000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0246
    Cell Significance Index: -0.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0269
    Cell Significance Index: -3.9200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0290
    Cell Significance Index: -1.3500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0429
    Cell Significance Index: -31.4500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0470
    Cell Significance Index: -6.0300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0484
    Cell Significance Index: -1.1600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0503
    Cell Significance Index: -38.0400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0553
    Cell Significance Index: -7.1400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0582
    Cell Significance Index: -32.8100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0719
    Cell Significance Index: -2.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0812
    Cell Significance Index: -4.2200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0895
    Cell Significance Index: -1.9400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0916
    Cell Significance Index: -1.5700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1026
    Cell Significance Index: -0.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1324
    Cell Significance Index: -27.8900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1440
    Cell Significance Index: -41.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1547
    Cell Significance Index: -15.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1840
    Cell Significance Index: -8.3400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1873
    Cell Significance Index: -21.3800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2072
    Cell Significance Index: -13.3700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2426
    Cell Significance Index: -5.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2457
    Cell Significance Index: -28.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2617
    Cell Significance Index: -30.5000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2719
    Cell Significance Index: -19.2300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2888
    Cell Significance Index: -30.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3770
    Cell Significance Index: -8.0300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.4746
    Cell Significance Index: -4.3700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4782
    Cell Significance Index: -7.0600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5172
    Cell Significance Index: -40.9600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5264
    Cell Significance Index: -7.7700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5472
    Cell Significance Index: -33.5500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5989
    Cell Significance Index: -8.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6226
    Cell Significance Index: -32.6900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.7587
    Cell Significance Index: -9.4100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7617
    Cell Significance Index: -24.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7770
    Cell Significance Index: -25.4400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7858
    Cell Significance Index: -27.3100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.8601
    Cell Significance Index: -22.6200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8870
    Cell Significance Index: -18.8300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** KPNA1 is a nuclear pore complex (NPC) subunit that is primarily located in the nucleoplasm. It is a multifunctional protein that exhibits a high degree of sequence homology with other importin-alpha subunits. KPNA1 has a characteristic NLS (nuclear localization signal) domain, which is essential for its nuclear import function. The protein also contains a C-terminal domain that interacts with other NPC subunits, facilitating its binding to the nuclear pore complex. KPNA1 has been shown to interact with various cellular proteins, including transcription factors, signaling molecules, and viral proteins, influencing their localization and activity. **Pathways and Functions** KPNA1 plays a critical role in various cellular pathways, including: 1. **Apoptosis**: KPNA1 is involved in the regulation of apoptotic processes, including the assembly of the orc (optimal reading frame) complex at the origin of replication and the regulation of canonical Wnt signaling pathway. 2. **Immune Response**: KPNA1 is essential for the transport of immune-related proteins into the nucleus, where they can interact with transcription factors and signaling molecules to regulate immune responses. 3. **Viral Infection**: KPNA1 is involved in the nuclear import of viral proteins, including Vpr (viral protein R), which is essential for the replication and transcription of HIV. 4. **DNA Replication**: KPNA1 regulates the assembly of the pre-replicative complex and the regulation of DNA recombination. 5. **Cytokine Signaling**: KPNA1 is involved in the regulation of cytokine signaling in the immune system, including the transport of cytokine receptors into the nucleus. **Clinical Significance** Dysregulation of KPNA1 has been implicated in several diseases, including: 1. **Cancer**: KPNA1 overexpression has been observed in various types of cancer, including breast, lung, and colon cancer. 2. **Neurodegenerative Disorders**: KPNA1 has been implicated in neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. 3. **Infectious Diseases**: KPNA1 plays a critical role in the replication and transcription of HIV, and its dysregulation has been implicated in HIV-related diseases. 4. **Immune System Disorders**: KPNA1 is involved in the regulation of immune responses, and its dysregulation has been implicated in autoimmune diseases, such as rheumatoid arthritis and lupus. In conclusion, KPNA1 is a multifunctional protein that plays a critical role in various cellular pathways, including apoptosis, immune response, and viral infection. Its dysregulation has been implicated in several diseases, highlighting the importance of KPNA1 in maintaining cellular homeostasis and regulating disease progression.

Genular Protein ID: 2908025333

Symbol: IMA5_HUMAN

Name: Importin subunit alpha-5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7831767

Title: NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein.

PubMed ID: 7831767

DOI: 10.1016/s0042-6822(95)80026-3

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8052633

Title: RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1.

PubMed ID: 8052633

DOI: 10.1073/pnas.91.16.7633

PubMed ID: 7892216

Title: Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes.

PubMed ID: 7892216

DOI: 10.1073/pnas.92.6.2008

PubMed ID: 8692858

Title: The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence.

PubMed ID: 8692858

DOI: 10.1073/pnas.93.13.6572

PubMed ID: 7604027

Title: Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.

PubMed ID: 7604027

DOI: 10.1073/pnas.92.14.6532

PubMed ID: 9463369

Title: Viral protein R regulates nuclear import of the HIV-1 pre-integration complex.

PubMed ID: 9463369

DOI: 10.1093/emboj/17.4.909

PubMed ID: 10612665

Title: Epstein-barr virus nuclear antigen-1 binds to nuclear transporter karyopherin alpha1/NPI-1 in addition to karyopherin alpha2/Rch1.

PubMed ID: 10612665

DOI: 10.1006/viro.1999.0054

PubMed ID: 12610148

Title: A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway.

PubMed ID: 12610148

DOI: 10.1128/jvi.77.6.3734-3748.2003

PubMed ID: 15942031

Title: Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).

PubMed ID: 15942031

DOI: 10.1093/nar/gki641

PubMed ID: 16698996

Title: Ebola virus VP24 binds karyopherin alpha-1 and blocks STAT1 nuclear accumulation.

PubMed ID: 16698996

DOI: 10.1128/jvi.02349-05

PubMed ID: 17652399

Title: Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2.

PubMed ID: 17652399

DOI: 10.1128/jvi.00371-07

PubMed ID: 17928350

Title: Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

PubMed ID: 17928350

DOI: 10.1128/jvi.01097-07

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19118899

Title: Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase.

PubMed ID: 19118899

DOI: 10.1016/j.molimm.2008.11.009

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21454664

Title: Importin alpha protein acts as a negative regulator for Snail protein nuclear import.

PubMed ID: 21454664

DOI: 10.1074/jbc.m110.213579

PubMed ID: 21385873

Title: CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31.

PubMed ID: 21385873

DOI: 10.1074/jbc.m110.208769

PubMed ID: 22500989

Title: Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A).

PubMed ID: 22500989

DOI: 10.1016/j.febslet.2012.02.053

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27713473

Title: Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation.

PubMed ID: 27713473

DOI: 10.1038/srep34614

PubMed ID: 28552616

Title: Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.

PubMed ID: 28552616

DOI: 10.1016/j.molcel.2017.04.026

PubMed ID: 29599122

Title: Intersectin goes nuclear: secret life of an endocytic protein.

PubMed ID: 29599122

DOI: 10.1042/bcj20170897

PubMed ID: 30576860

Title: Nucleocytoplasmic shuttling of the human parainfluenza virus type 2 phosphoprotein.

PubMed ID: 30576860

DOI: 10.1016/j.virol.2018.12.005

PubMed ID: 35446349

Title: Tumor suppressor BAP1 nuclear import is governed by transportin-1.

PubMed ID: 35446349

DOI: 10.1083/jcb.202201094

Sequence Information:

  • Length: 538
  • Mass: 60222
  • Checksum: E8407A3352D6051C
  • Sequence:
  • MTTPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV ATAEEETEEE 
    VMSDGGFHEA QISNMEMAPG GVITSDMIEM IFSKSPEQQL SATQKFRKLL SKEPNPPIDE 
    VISTPGVVAR FVEFLKRKEN CTLQFESAWV LTNIASGNSL QTRIVIQAGA VPIFIELLSS 
    EFEDVQEQAV WALGNIAGDS TMCRDYVLDC NILPPLLQLF SKQNRLTMTR NAVWALSNLC 
    RGKSPPPEFA KVSPCLNVLS WLLFVSDTDV LADACWALSY LSDGPNDKIQ AVIDAGVCRR 
    LVELLMHNDY KVVSPALRAV GNIVTGDDIQ TQVILNCSAL QSLLHLLSSP KESIKKEACW 
    TISNITAGNR AQIQTVIDAN IFPALISILQ TAEFRTRKEA AWAITNATSG GSAEQIKYLV 
    ELGCIKPLCD LLTVMDSKIV QVALNGLENI LRLGEQEAKR NGTGINPYCA LIEEAYGLDK 
    IEFLQSHENQ EIYQKAFDLI EHYFGTEDED SSIAPQVDLN QQQYIFQQCE APMEGFQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.