Details for: LAIR1

Gene ID: 3903

Symbol: LAIR1

Ensembl ID: ENSG00000167613

Description: leukocyte associated immunoglobulin like receptor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 73.1620
    Cell Significance Index: -11.3800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 25.7978
    Cell Significance Index: -13.2700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 17.9279
    Cell Significance Index: -12.0300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.1812
    Cell Significance Index: -11.3200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 5.7913
    Cell Significance Index: 89.6000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 3.5089
    Cell Significance Index: -0.8900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.9751
    Cell Significance Index: -11.7400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.3531
    Cell Significance Index: -5.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.2939
    Cell Significance Index: -6.1500
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 2.2007
    Cell Significance Index: 14.6000
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 2.0693
    Cell Significance Index: 13.2100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.4920
    Cell Significance Index: 32.6700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.2916
    Cell Significance Index: 83.3300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.1416
    Cell Significance Index: 21.1000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.1371
    Cell Significance Index: 28.4300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.6566
    Cell Significance Index: 19.2900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2991
    Cell Significance Index: 56.9200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2079
    Cell Significance Index: 187.7500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1827
    Cell Significance Index: 18.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1193
    Cell Significance Index: 2.5900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0626
    Cell Significance Index: 10.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0038
    Cell Significance Index: 0.7600
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.0018
    Cell Significance Index: 0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0016
    Cell Significance Index: -3.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0050
    Cell Significance Index: -0.5100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0053
    Cell Significance Index: -9.8100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0062
    Cell Significance Index: -9.5900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0083
    Cell Significance Index: -11.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0092
    Cell Significance Index: -3.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0104
    Cell Significance Index: -1.1400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0127
    Cell Significance Index: -9.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0170
    Cell Significance Index: -12.6200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0174
    Cell Significance Index: -0.6100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0175
    Cell Significance Index: -11.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0176
    Cell Significance Index: -12.8700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0186
    Cell Significance Index: -8.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0189
    Cell Significance Index: -10.3300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0228
    Cell Significance Index: -4.5200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0228
    Cell Significance Index: -12.8400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0258
    Cell Significance Index: -11.6900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0388
    Cell Significance Index: -0.9900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0388
    Cell Significance Index: -11.1500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0400
    Cell Significance Index: -2.5200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0408
    Cell Significance Index: -1.8500
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0409
    Cell Significance Index: -0.4100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0478
    Cell Significance Index: -2.9300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0499
    Cell Significance Index: -9.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0528
    Cell Significance Index: -1.5200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0544
    Cell Significance Index: -6.9800
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0571
    Cell Significance Index: -0.8400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0609
    Cell Significance Index: -12.8300
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0642
    Cell Significance Index: -0.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0672
    Cell Significance Index: -7.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0675
    Cell Significance Index: -7.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0692
    Cell Significance Index: -10.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0735
    Cell Significance Index: -10.0900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0741
    Cell Significance Index: -5.1300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0837
    Cell Significance Index: -14.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0844
    Cell Significance Index: -10.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0907
    Cell Significance Index: -11.7200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0997
    Cell Significance Index: -5.1800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1031
    Cell Significance Index: -10.7300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1050
    Cell Significance Index: -8.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1075
    Cell Significance Index: -12.3200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1214
    Cell Significance Index: -5.2800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1270
    Cell Significance Index: -5.9700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1343
    Cell Significance Index: -9.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1385
    Cell Significance Index: -3.8700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1579
    Cell Significance Index: -11.7700
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1731
    Cell Significance Index: -2.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1733
    Cell Significance Index: -9.1000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1738
    Cell Significance Index: -10.4400
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1855
    Cell Significance Index: -3.1500
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1862
    Cell Significance Index: -2.3600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1980
    Cell Significance Index: -9.2300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2022
    Cell Significance Index: -5.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2026
    Cell Significance Index: -11.3700
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.2236
    Cell Significance Index: -1.9700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2269
    Cell Significance Index: -7.9500
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.2321
    Cell Significance Index: -2.3700
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.2402
    Cell Significance Index: -2.1000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2504
    Cell Significance Index: -12.6600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2604
    Cell Significance Index: -11.5200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2743
    Cell Significance Index: -8.9800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2851
    Cell Significance Index: -9.0800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.2878
    Cell Significance Index: -4.0900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.2912
    Cell Significance Index: -5.0200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2922
    Cell Significance Index: -9.3600
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: -0.2955
    Cell Significance Index: -1.2300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3066
    Cell Significance Index: -11.6100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.3084
    Cell Significance Index: -6.0300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3187
    Cell Significance Index: -11.7000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3327
    Cell Significance Index: -7.0900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3509
    Cell Significance Index: -9.0200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3516
    Cell Significance Index: -8.7700
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.3621
    Cell Significance Index: -6.2200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3691
    Cell Significance Index: -3.0100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3761
    Cell Significance Index: -13.0700
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.3857
    Cell Significance Index: -5.6000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3942
    Cell Significance Index: -11.3000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LAIR1 is a type II transmembrane protein that belongs to the immunoglobulin superfamily. It is characterized by its unique structure, which consists of an extracellular immunoglobulin-like domain, a transmembrane domain, and an intracellular cytoplasmic domain. The protein is expressed on a variety of immune cells, including monocytes, macrophages, and thymocytes, as well as on certain non-immune cells, such as Hofbauer cells. LAIR1 is also known for its ability to interact with other immune molecules, including Fc receptors, integrins, and chemokine receptors. **Pathways and Functions:** LAIR1 is involved in several key immune pathways, including: 1. **Immune system regulation:** LAIR1 modulates the interactions between lymphoid and non-lymphoid cells, influencing the development, activation, and function of immune cells. 2. **Adaptive immune response:** LAIR1 is involved in the regulation of T cell activation, proliferation, and differentiation, as well as the production of cytokines and chemokines. 3. **Innate immune response:** LAIR1 interacts with pattern recognition receptors (PRRs) and Toll-like receptors (TLRs), influencing the recognition and response to pathogens. 4. **Neutrophil degranulation:** LAIR1 is involved in the regulation of neutrophil function, including degranulation and the production of reactive oxygen species. **Clinical Significance:** LAIR1 has been implicated in various immune-related disorders, including: 1. **Autoimmune diseases:** LAIR1 has been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where its dysregulation can contribute to immune system dysfunction. 2. **Cancer:** LAIR1 is overexpressed in certain types of cancer, including leukemia and lymphoma, where it may contribute to tumorigenesis and immune evasion. 3. **Infectious diseases:** LAIR1 has been implicated in the regulation of immune responses to infectious diseases, such as HIV and tuberculosis. In conclusion, LAIR1 is a critical component of the immune system that plays a pivotal role in regulating immune responses. Its dysregulation has been implicated in various immune-related disorders, highlighting the importance of LAIR1 in maintaining immune homeostasis. Further research is needed to fully elucidate the mechanisms by which LAIR1 regulates the immune system and to explore its therapeutic potential in immune-related diseases.

Genular Protein ID: 1157721331

Symbol: LAIR1_HUMAN

Name: Leukocyte-associated immunoglobulin-like receptor 1

UniProtKB Accession Codes:

Q6GTX8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 14 EvolutionaryTrace 1 ExpressionAtlas 1 GO 5 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 2 RefSeq 4 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9285412

Title: LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes.

PubMed ID: 9285412

DOI: 10.1016/s1074-7613(00)80530-0

PubMed ID: 10229813

Title: Leukocyte-associated Ig-like receptor-1 functions as an inhibitory receptor on cytotoxic T cells.

PubMed ID: 10229813

PubMed ID: 10764762

Title: Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells.

PubMed ID: 10764762

DOI: 10.1074/jbc.m001313200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9692876

Title: p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor.

PubMed ID: 9692876

DOI: 10.1002/(sici)1521-4141(199807)28:07<2086::aid-immu2086>3.0.co;2-t

PubMed ID: 10540327

Title: Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is differentially expressed during human B cell differentiation and inhibits B cell receptor-mediated signaling.

PubMed ID: 10540327

DOI: 10.1002/(sici)1521-4141(199910)29:10<3160::aid-immu3160>3.0.co;2-s

PubMed ID: 11069054

Title: Engagement of the leukocyte-associated Ig-like receptor-1 induces programmed cell death and prevents NF-kappaB nuclear translocation in human myeloid leukemias.

PubMed ID: 11069054

DOI: 10.1002/1521-4141(200010)30:10<2751::aid-immu2751>3.0.co;2-l

PubMed ID: 11160222

Title: Constitutive association of SHP-1 with leukocyte-associated Ig-like receptor-1 in human T cells.

PubMed ID: 11160222

DOI: 10.4049/jimmunol.166.3.1763

PubMed ID: 12072189

Title: Surface density expression of the leukocyte-associated Ig-like receptor-1 is directly related to inhibition of human T-cell functions.

PubMed ID: 12072189

DOI: 10.1016/s0198-8859(02)00409-3

PubMed ID: 14565933

Title: Differential contribution of the immunoreceptor tyrosine-based inhibitory motifs of human leukocyte-associated Ig-like receptor-1 to inhibitory function and phosphatase recruitment.

PubMed ID: 14565933

DOI: 10.1093/intimm/dxg134

PubMed ID: 12757266

Title: Chronic active Epstein-Barr virus infection associated with low expression of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) on natural killer cells.

PubMed ID: 12757266

DOI: 10.1023/a:1022580929226

PubMed ID: 14604962

Title: Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection.

PubMed ID: 14604962

DOI: 10.1182/blood-2003-07-2375

PubMed ID: 15939744

Title: Inhibitory receptors CD85j, LAIR-1, and CD152 down-regulate immunoglobulin and cytokine production by human B lymphocytes.

PubMed ID: 15939744

DOI: 10.1128/cdli.12.6.705-712.2005

PubMed ID: 15950745

Title: The inhibitory leukocyte-associated Ig-like receptor-1 (LAIR-1) is expressed at high levels by human naive T cells and inhibits TCR mediated activation.

PubMed ID: 15950745

DOI: 10.1016/j.molimm.2005.01.004

PubMed ID: 16380958

Title: Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase.

PubMed ID: 16380958

DOI: 10.1002/eji.200535226

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 20007810

Title: Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI.

PubMed ID: 20007810

DOI: 10.1182/blood-2009-10-246322

Sequence Information:

  • Length: 287
  • Mass: 31469
  • Checksum: E2A921D84F426B35
  • Sequence:
    • MSPHPTALLG LVLCLAQTIH TQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL 
ERDSRSTYND TEDVSQASPS ESEARFRIDS VREGNAGLYR CIYYKPPKWS EQSDYLELLV 
KESSGGPDSP DTEPGSSAGP TQRPSDNSHN EHAPASQGLK AEHLYILIGV SVVFLFCLLL 
LVLFCLHRQN QIKQGPPRSK DEEQKPQQRP DLAVDVLERT ADKATVNGLP EKDRETDTSA 
LAAGSSQEVT YAQLDHWALT QRTARAVSPQ STKPMAESIT YAAVARH

Genular Protein ID: 1322833300

Symbol: D3YTC8_HUMAN

Name: N/A

UniProtKB Accession Codes:

D3YTC8

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 286
  • Mass: 31340
  • Checksum: 53FCE0F650369F0D
  • Sequence:
    • MSPHPTALLG LVLCLAQTIH TQEDLPRPSI SAEPGTVIPL GSHVTFVCRG PVGVQTFRLE 
RDSRSTYNDT EDVSQASPSE SEARFRIDSV REGNAGLYRC IYYKPPKWSE QSDYLELLVK 
ESSGGPDSPD TEPGSSAGPT QRPSDNSHNE HAPASQGLKA EHLYILIGVS VVFLFCLLLL 
VLFCLHRQNQ IKQGPPRSKD EEQKPQQRPD LAVDVLERTA DKATVNGLPE KDRETDTSAL 
AAGSSQEVTY AQLDHWALTQ RTARAVSPQS TKPMAESITY AAVARH

Genular Protein ID: 3920772421

Symbol: A8MZ84_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8MZ84

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 269
  • Mass: 29690
  • Checksum: A8B327C4E6DA9B1A
  • Sequence:
    • MEREMEDLPR PSISAEPGTV IPLGSHVTFV CRGPVGVQTF RLERDSRSTY NDTEDVSQAS 
PSESEARFRI DSVREGNAGL YRCIYYKPPK WSEQSDYLEL LVKESSGGPD SPDTEPGSSA 
GPTQRPSDNS HNEHAPASQG LKAEHLYILI GVSVVFLFCL LLLVLFCLHR QNQIKQGPPR 
SKDEEQKPQQ RPDLAVDVLE RTADKATVNG LPEKDRETDT SALAAGSSQE VTYAQLDHWA 
LTQRTARAVS PQSTKPMAES ITYAAVARH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.