Details for: FADS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 194.7986
Cell Significance Index: -30.3000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 109.5633
Cell Significance Index: -27.7900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 71.7822
Cell Significance Index: -33.8900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 64.1958
Cell Significance Index: -26.0800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 26.1039
Cell Significance Index: -32.1900 - Cell Name: sebaceous gland cell (CL2000021)
Fold Change: 19.0908
Cell Significance Index: 24.7000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.2969
Cell Significance Index: -32.7400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 5.1952
Cell Significance Index: 166.4000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.1573
Cell Significance Index: -6.9100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.7612
Cell Significance Index: 61.2000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.5135
Cell Significance Index: 84.9300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4061
Cell Significance Index: 279.0400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.0466
Cell Significance Index: 28.0500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.7305
Cell Significance Index: 15.2900 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.7214
Cell Significance Index: 18.4300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6117
Cell Significance Index: 60.5100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6103
Cell Significance Index: 83.8100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.5483
Cell Significance Index: 34.5600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4954
Cell Significance Index: 99.3900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4807
Cell Significance Index: 262.5300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3068
Cell Significance Index: 212.1600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2805
Cell Significance Index: 178.1400 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.2789
Cell Significance Index: 2.1500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2720
Cell Significance Index: 14.2800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2632
Cell Significance Index: 237.6900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2398
Cell Significance Index: 45.6300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2255
Cell Significance Index: 80.8700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2179
Cell Significance Index: 5.7300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2153
Cell Significance Index: 35.0200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2045
Cell Significance Index: 26.2200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1609
Cell Significance Index: 17.5100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.1141
Cell Significance Index: 1.2400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1118
Cell Significance Index: 7.2200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.1066
Cell Significance Index: 80.6500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0836
Cell Significance Index: 128.7400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0744
Cell Significance Index: 140.0000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0553
Cell Significance Index: 102.0600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0541
Cell Significance Index: 1.9000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0259
Cell Significance Index: 35.1500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0102
Cell Significance Index: 1.7500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0056
Cell Significance Index: -2.5200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0073
Cell Significance Index: -0.2100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0120
Cell Significance Index: -0.7400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0124
Cell Significance Index: -9.1600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0152
Cell Significance Index: -9.4800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0174
Cell Significance Index: -7.6900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0175
Cell Significance Index: -3.1500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0328
Cell Significance Index: -24.0500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0345
Cell Significance Index: -0.7300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0375
Cell Significance Index: -4.2800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0384
Cell Significance Index: -21.6700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0516
Cell Significance Index: -2.6900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0536
Cell Significance Index: -1.3400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0632
Cell Significance Index: -6.4600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0654
Cell Significance Index: -9.5100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0659
Cell Significance Index: -13.8900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0739
Cell Significance Index: -1.9000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0863
Cell Significance Index: -3.9100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0937
Cell Significance Index: -26.9600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0980
Cell Significance Index: -1.6400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1036
Cell Significance Index: -7.1700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1041
Cell Significance Index: -6.3900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1262
Cell Significance Index: -15.5200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1299
Cell Significance Index: -3.4800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1440
Cell Significance Index: -16.5000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1702
Cell Significance Index: -19.8400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1849
Cell Significance Index: -4.0100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1987
Cell Significance Index: -15.2500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2010
Cell Significance Index: -25.9700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.2101
Cell Significance Index: -3.2500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2125
Cell Significance Index: -25.0600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2222
Cell Significance Index: -6.2100 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2414
Cell Significance Index: -7.0900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2813
Cell Significance Index: -29.2900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2867
Cell Significance Index: -20.2800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3028
Cell Significance Index: -20.3600 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3272
Cell Significance Index: -3.9000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3719
Cell Significance Index: -29.4600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3966
Cell Significance Index: -29.5600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4451
Cell Significance Index: -20.9200 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.4930
Cell Significance Index: -6.9100 - Cell Name: radial glial cell (CL0000681)
Fold Change: -0.4971
Cell Significance Index: -2.9500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.5261
Cell Significance Index: -6.5600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5275
Cell Significance Index: -9.0400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5313
Cell Significance Index: -27.6000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5497
Cell Significance Index: -25.6300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.5696
Cell Significance Index: -13.6600 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.5791
Cell Significance Index: -4.7800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5842
Cell Significance Index: -25.8400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.5996
Cell Significance Index: -16.0100 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.6505
Cell Significance Index: -8.2100 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.6635
Cell Significance Index: -11.1600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.6694
Cell Significance Index: -18.2200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.6838
Cell Significance Index: -20.1400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6974
Cell Significance Index: -26.4100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.7181
Cell Significance Index: -23.5100 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7182
Cell Significance Index: -25.1600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.7193
Cell Significance Index: -22.9100 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -0.7315
Cell Significance Index: -7.6200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.7421
Cell Significance Index: -16.2500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2465164299
Symbol: FADS1_HUMAN
Name: Delta(5) fatty acid desaturase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10601301
Title: Cloning, expression, and fatty acid regulation of the human Delta-5 desaturase.
PubMed ID: 10601301
PubMed ID: 10769175
Title: cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid.
PubMed ID: 10769175
DOI: 10.1042/bj3470719
PubMed ID: 10860662
Title: cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.
PubMed ID: 10860662
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22619218
Title: A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids.
PubMed ID: 22619218
DOI: 10.1194/jlr.m025312
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 25732826
Title: An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.
PubMed ID: 25732826
Sequence Information:
- Length: 444
- Mass: 51964
- Checksum: CC3C28D82AA49BF2
- Sequence:
MAPDPVAAET AAQGPTPRYF TWDEVAQRSG CEERWLVIDR KVYNISEFTR RHPGGSRVIS HYAGQDATDP FVAFHINKGL VKKYMNSLLI GELSPEQPSF EPTKNKELTD EFRELRATVE RMGLMKANHV FFLLYLLHIL LLDGAAWLTL WVFGTSFLPF LLCAVLLSAV QAQAGWLQHD FGHLSVFSTS KWNHLLHHFV IGHLKGAPAS WWNHMHFQHH AKPNCFRKDP DINMHPFFFA LGKILSVELG KQKKKYMPYN HQHKYFFLIG PPALLPLYFQ WYIFYFVIQR KKWVDLAWMI TFYVRFFLTY VPLLGLKAFL GLFFIVRFLE SNWFVWVTQM NHIPMHIDHD RNMDWVSTQL QATCNVHKSA FNDWFSGHLN FQIEHHLFPT MPRHNYHKVA PLVQSLCAKH GIEYQSKPLL SAFADIIHSL KESGQLWLDA YLHQ
Genular Protein ID: 1958973775
Symbol: A0A0A0MR51_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
Sequence Information:
- Length: 501
- Mass: 57886
- Checksum: DB59ACB64C59B329
- Sequence:
MGTRAARPAG LPCGAENPAR RRLALGARQQ IHSWSPRTPS TRLTAPAGPA RGVARPAMAP DPVAAETAAQ GPTPRYFTWD EVAQRSGCEE RWLVIDRKVY NISEFTRRHP GGSRVISHYA GQDATDPFVA FHINKGLVKK YMNSLLIGEL SPEQPSFEPT KNKELTDEFR ELRATVERMG LMKANHVFFL LYLLHILLLD GAAWLTLWVF GTSFLPFLLC AVLLSAVQAQ AGWLQHDFGH LSVFSTSKWN HLLHHFVIGH LKGAPASWWN HMHFQHHAKP NCFRKDPDIN MHPFFFALGK ILSVELGKQK KKYMPYNHQH KYFFLIGPPA LLPLYFQWYI FYFVIQRKKW VDLAWMITFY VRFFLTYVPL LGLKAFLGLF FIVRFLESNW FVWVTQMNHI PMHIDHDRNM DWVSTQLQAT CNVHKSAFND WFSGHLNFQI EHHLFPTMPR HNYHKVAPLV QSLCAKHGIE YQSKPLLSAF ADIIHSLKES GQLWLDAYLH Q
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.