Details for: LLGL2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 106.2071
Cell Significance Index: -16.5200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 63.6918
Cell Significance Index: -16.1600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 40.2701
Cell Significance Index: -16.3600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 25.8263
Cell Significance Index: -17.3300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 17.0831
Cell Significance Index: -16.3100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.4068
Cell Significance Index: -16.5300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.0063
Cell Significance Index: -16.0900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 5.0915
Cell Significance Index: 230.7800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 5.0313
Cell Significance Index: 75.3900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 5.0185
Cell Significance Index: 347.0600 - Cell Name: epithelial cell of sweat gland (CL1000448)
Fold Change: 5.0094
Cell Significance Index: 3.5800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.2124
Cell Significance Index: -16.6200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.1218
Cell Significance Index: -12.6600 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 2.9590
Cell Significance Index: 29.8500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 2.8732
Cell Significance Index: 34.2500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.7278
Cell Significance Index: -5.9700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 2.5899
Cell Significance Index: 281.7000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.4114
Cell Significance Index: 32.9000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.0171
Cell Significance Index: 104.7800 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 1.8699
Cell Significance Index: 20.2700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.8594
Cell Significance Index: 302.4100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.8167
Cell Significance Index: 360.5400 - Cell Name: epidermal cell (CL0000362)
Fold Change: 1.7609
Cell Significance Index: 3.9700 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 1.2788
Cell Significance Index: 7.8700 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.1291
Cell Significance Index: 13.1300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.0914
Cell Significance Index: 30.5000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.0838
Cell Significance Index: 68.3100 - Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: 1.0627
Cell Significance Index: 5.9200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.0276
Cell Significance Index: 47.9100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.9703
Cell Significance Index: 8.9400 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.8785
Cell Significance Index: 5.4200 - Cell Name: peg cell (CL4033014)
Fold Change: 0.8748
Cell Significance Index: 20.2100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8667
Cell Significance Index: 30.4600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.8386
Cell Significance Index: 457.9900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7831
Cell Significance Index: 77.4700 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.7561
Cell Significance Index: 10.6200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.7420
Cell Significance Index: 133.7600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5867
Cell Significance Index: 15.9700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5533
Cell Significance Index: 68.0300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.5353
Cell Significance Index: 91.4000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4938
Cell Significance Index: 23.2100 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 0.4275
Cell Significance Index: 1.6100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.3416
Cell Significance Index: 7.2800 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 0.2818
Cell Significance Index: 2.8200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2196
Cell Significance Index: 16.3700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.2065
Cell Significance Index: 3.2000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.2012
Cell Significance Index: 6.4500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1874
Cell Significance Index: 35.6700 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.1756
Cell Significance Index: 2.5000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1666
Cell Significance Index: 4.8000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1513
Cell Significance Index: 4.0600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.1351
Cell Significance Index: 2.2800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1192
Cell Significance Index: 52.7200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1162
Cell Significance Index: 8.2200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1143
Cell Significance Index: 103.2100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0964
Cell Significance Index: 148.3400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0760
Cell Significance Index: 55.7300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0637
Cell Significance Index: 86.6300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0606
Cell Significance Index: 7.8300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0603
Cell Significance Index: 12.1000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0484
Cell Significance Index: 89.2300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0326
Cell Significance Index: 61.3000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0278
Cell Significance Index: 17.6700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0180
Cell Significance Index: 13.6400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0011
Cell Significance Index: 0.6600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0026
Cell Significance Index: -1.9500 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: -0.0048
Cell Significance Index: -0.0500 - Cell Name: columnar/cuboidal epithelial cell (CL0000075)
Fold Change: -0.0131
Cell Significance Index: -0.0500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0174
Cell Significance Index: -2.5300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0174
Cell Significance Index: -6.2600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0195
Cell Significance Index: -11.0200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0212
Cell Significance Index: -1.3700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0245
Cell Significance Index: -5.1500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0284
Cell Significance Index: -12.9000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0379
Cell Significance Index: -4.3300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0409
Cell Significance Index: -5.6200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0441
Cell Significance Index: -12.6800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0496
Cell Significance Index: -5.0700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0532
Cell Significance Index: -6.0900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0571
Cell Significance Index: -7.3300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0799
Cell Significance Index: -1.7300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0950
Cell Significance Index: -11.0700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1058
Cell Significance Index: -5.5100 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1058
Cell Significance Index: -1.1000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1188
Cell Significance Index: -9.4100 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.1220
Cell Significance Index: -0.9400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1314
Cell Significance Index: -13.6800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1333
Cell Significance Index: -15.7200 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.1387
Cell Significance Index: -1.0600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1592
Cell Significance Index: -4.2500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1782
Cell Significance Index: -2.6300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1845
Cell Significance Index: -14.1600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1862
Cell Significance Index: -10.4500 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.1985
Cell Significance Index: -4.1400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2111
Cell Significance Index: -3.6200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2222
Cell Significance Index: -13.6200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2308
Cell Significance Index: -5.7700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2324
Cell Significance Index: -15.6300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2496
Cell Significance Index: -12.6200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.2642
Cell Significance Index: -5.4800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1358482829
Symbol: L2GL2_HUMAN
Name: LLGL scribble cell polarity complex component 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15632202
Title: Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.
PubMed ID: 15632202
PubMed ID: 12725730
Title: Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.
PubMed ID: 12725730
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20644714
Title: Involvement of Lgl and Mahjong/VprBP in cell competition.
PubMed ID: 20644714
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1020
- Mass: 113448
- Checksum: 9C36BFF9F94314B5
- Sequence:
MRRFLRPGHD PVRERLKRDL FQFNKTVEHG FPHQPSALGY SPSLRILAIG TRSGAIKLYG APGVEFMGLH QENNAVTQIH LLPGQCQLVT LLDDNSLHLW SLKVKGGASE LQEDESFTLR GPPGAAPSAT QITVVLPHSS CELLYLGTES GNVFVVQLPA FRALEDRTIS SDAVLQRLPE EARHRRVFEM VEALQEHPRD PNQILIGYSR GLVVIWDLQG SRVLYHFLSS QQLENIWWQR DGRLLVSCHS DGSYCQWPVS SEAQQPEPLR SLVPYGPFPC KAITRILWLT TRQGLPFTIF QGGMPRASYG DRHCISVIHD GQQTAFDFTS RVIGFTVLTE ADPAATFDDP YALVVLAEEE LVVIDLQTAG WPPVQLPYLA SLHCSAITCS HHVSNIPLKL WERIIAAGSR QNAHFSTMEW PIDGGTSLTP APPQRDLLLT GHEDGTVRFW DASGVCLRLL YKLSTVRVFL TDTDPNENFS AQGEDEWPPL RKVGSFDPYS DDPRLGIQKI FLCKYSGYLA VAGTAGQVLV LELNDEAAEQ AVEQVEADLL QDQEGYRWKG HERLAARSGP VRFEPGFQPF VLVQCQPPAV VTSLALHSEW RLVAFGTSHG FGLFDHQQRR QVFVKCTLHP SDQLALEGPL SRVKSLKKSL RQSFRRMRRS RVSSRKRHPA GPPGEAQEGS AKAERPGLQN MELAPVQRKI EARSAEDSFT GFVRTLYFAD TYLKDSSRHC PSLWAGTNGG TIYAFSLRVP PAERRMDEPV RAEQAKEIQL MHRAPVVGIL VLDGHSVPLP EPLEVAHDLS KSPDMQGSHQ LLVVSEEQFK VFTLPKVSAK LKLKLTALEG SRVRRVSVAH FGSRRAEDYG EHHLAVLTNL GDIQVVSLPL LKPQVRYSCI RREDVSGIAS CVFTKYGQGF YLISPSEFER FSLSTKWLVE PRCLVDSAET KNHRPGNGAG PKKAPSRARN SGTQSDGEEK QPGLVMERAL LSDERVLKEI QSTLEGDRGS GNWRSHRAAV GCSLSNGGAE
Genular Protein ID: 2775581295
Symbol: A0PJJ0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 271
- Mass: 29831
- Checksum: 7E5675D861523139
- Sequence:
VPPAERRMDE PVRAEQAKEI QLMHRAPVVG ILVLDGHSVP LPEPLEVAHD LSKSPDMQGS HQLLVVSEEQ FKVFTLPKVS AKLKLKLTAL EGSRVRRVSV AHFGSRRAED YGEHHLAVLT NLGDIQVVSL PLLKPQVRYS CIRREDVSGI ASCVFTKYGQ GFYLISPSEF ERFSLSTKWL VEPRCLVDSA ETKNHRPGNG AGPKKAPSRA RNSGTQSDGE EKQPGLVMER ALLSDERVLK EIQSTLEGDR GSGNWRSHRA AVGCSLSNGG E
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.