Details for: LLGL1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 1.58
Marker Score: 4469 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.51
Marker Score: 1208 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71804.5 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48029 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30407 - Cell Name: germ cell (CL0000586)
Fold Change: 0.97
Marker Score: 1691 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 495 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.95
Marker Score: 449 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2411 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2732 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5179 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 314 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5278 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.84
Marker Score: 570 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1260 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.74
Marker Score: 384 - Cell Name: brush cell (CL0002204)
Fold Change: 0.73
Marker Score: 665 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.7
Marker Score: 533.5 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.68
Marker Score: 274.5 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.65
Marker Score: 2742 - Cell Name: Unknown (CL0002371)
Fold Change: 0.61
Marker Score: 643 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.57
Marker Score: 1335 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.55
Marker Score: 3606 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.55
Marker Score: 178 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 437 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.51
Marker Score: 328.5 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.49
Marker Score: 154.5 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.48
Marker Score: 1301 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.47
Marker Score: 1113 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.46
Marker Score: 500 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.44
Marker Score: 474 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.44
Marker Score: 637 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.44
Marker Score: 753 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.44
Marker Score: 4381.5 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.43
Marker Score: 5730 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.41
Marker Score: 382 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.4
Marker Score: 959 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.38
Marker Score: 211 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.38
Marker Score: 455 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.37
Marker Score: 210 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.37
Marker Score: 105 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.36
Marker Score: 194 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.36
Marker Score: 742 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.35
Marker Score: 351 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.35
Marker Score: 435 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.34
Marker Score: 109 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.34
Marker Score: 322 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.31
Marker Score: 130 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.3
Marker Score: 198 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.3
Marker Score: 186 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 0.29
Marker Score: 101 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.29
Marker Score: 79 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.29
Marker Score: 190 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.29
Marker Score: 278 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.28
Marker Score: 147 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.28
Marker Score: 278 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.28
Marker Score: 72 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.27
Marker Score: 95 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.27
Marker Score: 418 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.27
Marker Score: 1036 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.26
Marker Score: 196 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.26
Marker Score: 171 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.25
Marker Score: 106 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.25
Marker Score: 103 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.25
Marker Score: 104 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.25
Marker Score: 1483 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.25
Marker Score: 174.5 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.24
Marker Score: 2132 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.24
Marker Score: 120 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.24
Marker Score: 64 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.24
Marker Score: 813 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.23
Marker Score: 90 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.23
Marker Score: 4896 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.23
Marker Score: 87 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.23
Marker Score: 53 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.22
Marker Score: 936.5 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.22
Marker Score: 57 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.22
Marker Score: 45 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.22
Marker Score: 343 - Cell Name: Unknown (CL0000548)
Fold Change: 0.22
Marker Score: 162 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.22
Marker Score: 192 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.22
Marker Score: 63 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.22
Marker Score: 48 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.22
Marker Score: 247 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.22
Marker Score: 1618 - Cell Name: osteoblast (CL0000062)
Fold Change: 0.22
Marker Score: 116 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.22
Marker Score: 62 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.21
Marker Score: 122 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.21
Marker Score: 1836 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.21
Marker Score: 45 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.2
Marker Score: 185 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2
Marker Score: 68 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.2
Marker Score: 218 - Cell Name: Schwann cell precursor (CL0002375)
Fold Change: 0.2
Marker Score: 49 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.2
Marker Score: 190 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.2
Marker Score: 207 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.19
Marker Score: 57 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.19
Marker Score: 186.5 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.19
Marker Score: 170
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Other Information
Genular Protein ID: 1135981185
Symbol: L2GL1_HUMAN
Name: Lethal(2) giant larvae protein homolog 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7542763
Title: A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.
PubMed ID: 7542763
PubMed ID: 8565641
Title: The human homologue of the murine Llglh gene (LLGL) maps within the Smith-Magenis syndrome region in 17p11.2.
PubMed ID: 8565641
DOI: 10.1159/000134167
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12725730
Title: Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.
PubMed ID: 12725730
PubMed ID: 15735678
Title: Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer.
PubMed ID: 15735678
PubMed ID: 16170365
Title: Expression of Hugl-1 is strongly reduced in malignant melanoma.
PubMed ID: 16170365
PubMed ID: 20644714
Title: Involvement of Lgl and Mahjong/VprBP in cell competition.
PubMed ID: 20644714
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
Sequence Information:
- Length: 1064
- Mass: 115418
- Checksum: 9318D6736934E4D5
- Sequence:
MMKFRFRRQG ADPQREKLKQ ELFAFNKTVE HGFPNQPSAL AFDPELRIMA IGTRSGAVKI YGAPGVEFTG LHRDAATVTQ MHFLTGQGRL LSLLDDSSLH LWEIVHHNGC AHLEEALSFQ LPSRPGFDGA SAPLSLTRVT VVLLVAASDI AALGTEGSSV FFLDVTTLTL LEGQTLAPGE VLRSVPDDYR CGKALGPVES LQGHLRDPTK ILIGYSRGLL VIWNQASQCV DHIFLGNQQL ESLCWGRDSS TVVSSHSDGS YAVWSVDAGS FPTLQPTVAT TPYGPFPCKA INKILWRNCE SGGHFIIFSG GMPRASYGDR HCVSVLRAET LVTLDFTSRI IDFFTVHSTR PEDEFDDPQA LAVLLEEELV VLDLQTPGWP AVPAPYLAPL HSSAITCSAH VASVPAKLWA RIVSAGEQQS PQPVSSALSW PITGGRNLAQ EPSQRGLLLT GHEDGTVRFW DASGVALRPL YKLSTAGLFQ TDCEHADSLA QAAEDDWPPF RKVGCFDPYS DDPRLGVQKV ALCKYTAQMV VAGTAGQVLV LELSDVPVEQ AVSVAIIDLL QDREGFTWKG HERLSPRTGP LPWPAGFQPR VLVQCLPPAA VTAVTLHTEW SLVAFGTSHG FGLFDYQRKS PVLARCTLHP NDSLAMEGPL SRVKSLKKSL RQSFRRIRKS RVSGKKRAAN ASSKLQEANA QLAEQACPHD VEMTPVQRRI EPRSADDSLS GVVRCLYFAD TFLRDGAHHG PTMWAGTNSG SVFAYALEVP AAAVGGEKRP EQAVEAVLGK EVQLMHRAPV VAIAVLDGRG RPLPEPYEAS RDLAQAPDMQ GGHAVLIASE EQFKVFTLPK VSAKTKFKLT AHEGCRVRKV ALATFASVAC EDYAETCLAC LTNLGDVHVF SVPGLRPQVH YSCIRKEDIS GIASCVFTRH GQGFYLISPS EFERFSLSAR NITEPLCSLD INWPRDATQA SYRIRESPKL SQANGTPSIL LAPQSLDGSP DPAHSMGPDT PEPPEAALSP MSIDSATSAD TTLDTTGDVT VEDVKDFLGS SEESEKNLRN LAEDEAHACA ILIK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.