Details for: MARS1

Gene ID: 4141

Symbol: MARS1

Ensembl ID: ENSG00000166986

Description: methionyl-tRNA synthetase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 148.8956
    Cell Significance Index: -23.1600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 94.3056
    Cell Significance Index: -23.9200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 59.2219
    Cell Significance Index: -27.9600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 58.9036
    Cell Significance Index: -23.9300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 41.6678
    Cell Significance Index: -27.9600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 25.2529
    Cell Significance Index: -24.1100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.0166
    Cell Significance Index: -25.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.7105
    Cell Significance Index: -26.4800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.7725
    Cell Significance Index: -10.4500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1057
    Cell Significance Index: 221.8000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9198
    Cell Significance Index: 12.5500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8047
    Cell Significance Index: 87.5300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7946
    Cell Significance Index: 285.0000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7907
    Cell Significance Index: 128.6100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5748
    Cell Significance Index: 519.0400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5202
    Cell Significance Index: 103.2400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4577
    Cell Significance Index: 45.2800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4404
    Cell Significance Index: 12.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3890
    Cell Significance Index: 24.5200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3681
    Cell Significance Index: 10.0200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3374
    Cell Significance Index: 9.4300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3098
    Cell Significance Index: 58.9500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2995
    Cell Significance Index: 53.9900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2833
    Cell Significance Index: 13.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2814
    Cell Significance Index: 33.1800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2603
    Cell Significance Index: 13.5200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2140
    Cell Significance Index: 116.8600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2134
    Cell Significance Index: 147.5700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2123
    Cell Significance Index: 9.9000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1914
    Cell Significance Index: 14.6900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1768
    Cell Significance Index: 3.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1652
    Cell Significance Index: 20.3200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1528
    Cell Significance Index: 9.8600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1455
    Cell Significance Index: 64.3200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1071
    Cell Significance Index: 13.8400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0781
    Cell Significance Index: 5.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0717
    Cell Significance Index: 3.7400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0697
    Cell Significance Index: 3.1600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0620
    Cell Significance Index: 114.2600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0589
    Cell Significance Index: 8.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0543
    Cell Significance Index: 2.8500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0317
    Cell Significance Index: 48.8000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0297
    Cell Significance Index: 5.0700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0283
    Cell Significance Index: 0.8100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0263
    Cell Significance Index: 0.4400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0261
    Cell Significance Index: 49.1700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0239
    Cell Significance Index: 0.7600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0189
    Cell Significance Index: 25.7200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0121
    Cell Significance Index: 0.6800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0076
    Cell Significance Index: 4.8300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0050
    Cell Significance Index: 0.0600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0030
    Cell Significance Index: 0.0800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0021
    Cell Significance Index: -1.6100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0122
    Cell Significance Index: -0.6200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0215
    Cell Significance Index: -9.7500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0233
    Cell Significance Index: -1.5700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0235
    Cell Significance Index: -17.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0298
    Cell Significance Index: -1.3200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0317
    Cell Significance Index: -4.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0335
    Cell Significance Index: -24.8400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0408
    Cell Significance Index: -0.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0411
    Cell Significance Index: -5.9800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0416
    Cell Significance Index: -4.2500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0455
    Cell Significance Index: -25.6600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0470
    Cell Significance Index: -29.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0596
    Cell Significance Index: -1.9100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0657
    Cell Significance Index: -1.6900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0728
    Cell Significance Index: -1.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0794
    Cell Significance Index: -22.8500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0803
    Cell Significance Index: -5.6800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0940
    Cell Significance Index: -3.5600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0999
    Cell Significance Index: -11.4500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1386
    Cell Significance Index: -29.1900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1415
    Cell Significance Index: -3.7200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1581
    Cell Significance Index: -2.2500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1662
    Cell Significance Index: -3.6400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1689
    Cell Significance Index: -4.8200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2017
    Cell Significance Index: -7.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2108
    Cell Significance Index: -6.1900
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.2344
    Cell Significance Index: -1.7700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2356
    Cell Significance Index: -24.5300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2470
    Cell Significance Index: -6.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2600
    Cell Significance Index: -6.5000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2618
    Cell Significance Index: -5.4800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2968
    Cell Significance Index: -2.4200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3178
    Cell Significance Index: -25.1700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3699
    Cell Significance Index: -22.6800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.4023
    Cell Significance Index: -3.7100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4132
    Cell Significance Index: -8.7700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4515
    Cell Significance Index: -8.3500
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.4859
    Cell Significance Index: -6.8200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4882
    Cell Significance Index: -15.5500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4938
    Cell Significance Index: -6.1300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4944
    Cell Significance Index: -9.6500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4985
    Cell Significance Index: -16.3200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5180
    Cell Significance Index: -12.6400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5470
    Cell Significance Index: -20.0800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.5564
    Cell Significance Index: -8.4500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5601
    Cell Significance Index: -19.6200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5819
    Cell Significance Index: -15.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MARS1 is a cytosolic enzyme that catalyzes the attachment of methionine to its corresponding tRNA molecule, forming methionyl-tRNA. This reaction is essential for the translation of methionine-containing proteins, which play critical roles in various cellular processes, including protein synthesis, cell growth, and differentiation. MARS1 is a member of the aminoacyl-tRNA synthetase multienzyme complex, which consists of multiple enzymes that work together to synthesize and modify aminoacyl-tRNAs. **Pathways and Functions:** MARS1 is involved in several cellular pathways, including: 1. **Aminoacyl-tRNA synthesis**: MARS1 catalyzes the attachment of methionine to its corresponding tRNA molecule, forming methionyl-tRNA. 2. **Protein translation**: Methionyl-tRNA is a crucial component of protein synthesis, and MARS1 plays a vital role in ensuring the accuracy and efficiency of this process. 3. **Cell growth and differentiation**: Methionine-containing proteins play critical roles in cell growth and differentiation, and MARS1 is essential for the proper functioning of these processes. 4. **Selenoamino acid metabolism**: MARS1 is involved in the synthesis of selenomethionine, a selenium-containing amino acid that is essential for various cellular processes. **Clinical Significance:** Dysregulation of MARS1 has been implicated in various human diseases, including: 1. **Neurodegenerative disorders**: Mutations in the MARS1 gene have been linked to neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). 2. **Cancer**: Overexpression of MARS1 has been observed in certain types of cancer, including breast cancer and colorectal cancer. 3. **Neurodevelopmental disorders**: MARS1 has been implicated in neurodevelopmental disorders, such as autism spectrum disorder (ASD) and schizophrenia. In conclusion, MARS1 is a critical enzyme involved in various cellular processes, including protein synthesis, cell growth, and differentiation. Its dysregulation has been implicated in various human diseases, highlighting the importance of further research into the role of MARS1 in human health and disease.

Genular Protein ID: 1708046842

Symbol: SYMC_HUMAN

Name: Methionine--tRNA ligase, cytoplasmic

UniProtKB Accession Codes:

P56192 B3KVK7 Q14895 Q53H14 Q96A15 Q96BZ0 Q9NSE0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CORUM 1 CPTAC 2 CTD 1 CarbonylDB 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 1 EMBL 12 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 5 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 15 KEGG 1 MANE-Select 1 MIM 9 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 MoonProt 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 1 Rhea 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8921912

Title: Cloning of a human cDNA encoding a protein with high homology to yeast methionyl-tRNA synthetase.

PubMed ID: 8921912

DOI: 10.1016/0378-1119(96)00313-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10791971

Title: Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis.

PubMed ID: 10791971

DOI: 10.1083/jcb.149.3.567

PubMed ID: 11714285

Title: The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function.

PubMed ID: 11714285

DOI: 10.1021/bi015670b

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19131329

Title: Dissection of the structural organization of the aminoacyl-tRNA synthetase complex.

PubMed ID: 19131329

DOI: 10.1074/jbc.m809636200

PubMed ID: 19289464

Title: Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.

PubMed ID: 19289464

DOI: 10.1074/jbc.m900480200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23729695

Title: Exome sequencing identifies a significant variant in methionyl-tRNA synthetase (MARS) in a family with late-onset CMT2.

PubMed ID: 23729695

DOI: 10.1136/jnnp-2013-305049

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24354524

Title: Rare variants in methionyl- and tyrosyl-tRNA synthetase genes in late-onset autosomal dominant Charcot-Marie-Tooth neuropathy.

PubMed ID: 24354524

DOI: 10.1111/cge.12327

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 33909043

Title: Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy.

PubMed ID: 33909043

DOI: 10.1093/hmg/ddab123

PubMed ID: 34585293

Title: Four pedigrees with aminoacyl-tRNA synthetase abnormalities.

PubMed ID: 34585293

DOI: 10.1007/s10072-021-05626-z

PubMed ID: 26472928

Title: Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains.

PubMed ID: 26472928

DOI: 10.1074/jbc.m115.690867

PubMed ID: 24103465

Title: Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype.

PubMed ID: 24103465

DOI: 10.1186/1471-2350-14-106

PubMed ID: 24482476

Title: Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders.

PubMed ID: 24482476

DOI: 10.1126/science.1247363

PubMed ID: 25913036

Title: Biallelic mutations of methionyl-tRNA synthetase cause a specific type of pulmonary alveolar proteinosis prevalent on Reunion island.

PubMed ID: 25913036

DOI: 10.1016/j.ajhg.2015.03.010

Sequence Information:

  • Length: 900
  • Mass: 101116
  • Checksum: 3D687C77E17C5C96
  • Sequence:
    • MRLFVSDGVP GCLPVLAAAG RARGRAEVLI STVGPEDCVV PFLTRPKVPV LQLDSGNYLF 
STSAICRYFF LLSGWEQDDL TNQWLEWEAT ELQPALSAAL YYLVVQGKKG EDVLGSVRRA 
LTHIDHSLSR QNCPFLAGET ESLADIVLWG ALYPLLQDPA YLPEELSALH SWFQTLSTQE 
PCQRAAETVL KQQGVLALRP YLQKQPQPSP AEGRAVTNEP EEEELATLSE EEIAMAVTAW 
EKGLESLPPL RPQQNPVLPV AGERNVLITS ALPYVNNVPH LGNIIGCVLS ADVFARYSRL 
RQWNTLYLCG TDEYGTATET KALEEGLTPQ EICDKYHIIH ADIYRWFNIS FDIFGRTTTP 
QQTKITQDIF QQLLKRGFVL QDTVEQLRCE HCARFLADRF VEGVCPFCGY EEARGDQCDK 
CGKLINAVEL KKPQCKVCRS CPVVQSSQHL FLDLPKLEKR LEEWLGRTLP GSDWTPNAQF 
ITRSWLRDGL KPRCITRDLK WGTPVPLEGF EDKVFYVWFD ATIGYLSITA NYTDQWERWW 
KNPEQVDLYQ FMAKDNVPFH SLVFPCSALG AEDNYTLVSH LIATEYLNYE DGKFSKSRGV 
GVFGDMAQDT GIPADIWRFY LLYIRPEGQD SAFSWTDLLL KNNSELLNNL GNFINRAGMF 
VSKFFGGYVP EMVLTPDDQR LLAHVTLELQ HYHQLLEKVR IRDALRSILT ISRHGNQYIQ 
VNEPWKRIKG SEADRQRAGT VTGLAVNIAA LLSVMLQPYM PTVSATIQAQ LQLPPPACSI 
LLTNFLCTLP AGHQIGTVSP LFQKLENDQI ESLRQRFGGG QAKTSPKPAV VETVTTAKPQ 
QIQALMDEVT KQGNIVRELK AQKADKNEVA AEVAKLLDLK KQLAVAEGKP PEAPKGKKKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.