Details for: FOXO4

Gene ID: 4303

Symbol: FOXO4

Ensembl ID: ENSG00000184481

Description: forkhead box O4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 40.4384
    Cell Significance Index: -6.2900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 28.6623
    Cell Significance Index: -7.2700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 19.8083
    Cell Significance Index: -8.1600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 15.8766
    Cell Significance Index: -6.4500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.1908
    Cell Significance Index: -6.4000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 4.4129
    Cell Significance Index: 117.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.9789
    Cell Significance Index: 106.6200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.8314
    Cell Significance Index: -7.5900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.9412
    Cell Significance Index: -7.6600
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.6206
    Cell Significance Index: 8.0900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.4423
    Cell Significance Index: -4.4300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.9687
    Cell Significance Index: -2.1200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8377
    Cell Significance Index: 756.3700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8253
    Cell Significance Index: 11.2600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5581
    Cell Significance Index: 60.7100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5240
    Cell Significance Index: 23.7500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5111
    Cell Significance Index: 83.1200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5015
    Cell Significance Index: 30.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4061
    Cell Significance Index: 47.3300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3683
    Cell Significance Index: 7.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3290
    Cell Significance Index: 22.7500
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.3230
    Cell Significance Index: 3.7200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3098
    Cell Significance Index: 30.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3022
    Cell Significance Index: 15.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2402
    Cell Significance Index: 6.9200
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.2307
    Cell Significance Index: 0.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2015
    Cell Significance Index: 3.0200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1609
    Cell Significance Index: 8.3600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.1384
    Cell Significance Index: 1.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1209
    Cell Significance Index: 3.2900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0842
    Cell Significance Index: 16.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0663
    Cell Significance Index: 2.3300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0484
    Cell Significance Index: 1.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0483
    Cell Significance Index: 2.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0447
    Cell Significance Index: 2.8200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0445
    Cell Significance Index: 6.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0403
    Cell Significance Index: 5.1600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0322
    Cell Significance Index: 3.9600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0276
    Cell Significance Index: 12.2000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0265
    Cell Significance Index: 5.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0247
    Cell Significance Index: 0.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0240
    Cell Significance Index: 0.6000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0230
    Cell Significance Index: 4.1500
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.0215
    Cell Significance Index: 0.1400
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.0166
    Cell Significance Index: 0.2100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0162
    Cell Significance Index: 5.8200
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0133
    Cell Significance Index: 0.1900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0091
    Cell Significance Index: 6.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0083
    Cell Significance Index: 4.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0023
    Cell Significance Index: -4.3700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0036
    Cell Significance Index: -0.7200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0052
    Cell Significance Index: -3.8100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0059
    Cell Significance Index: -10.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0072
    Cell Significance Index: -11.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0080
    Cell Significance Index: -6.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0081
    Cell Significance Index: -11.0200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0089
    Cell Significance Index: -5.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0108
    Cell Significance Index: -1.8500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0126
    Cell Significance Index: -9.3500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0147
    Cell Significance Index: -8.2800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0150
    Cell Significance Index: -4.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0154
    Cell Significance Index: -7.0000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0187
    Cell Significance Index: -11.6500
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0200
    Cell Significance Index: -0.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0255
    Cell Significance Index: -3.3000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0273
    Cell Significance Index: -1.7600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0306
    Cell Significance Index: -2.1700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0315
    Cell Significance Index: -3.2200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0321
    Cell Significance Index: -1.5100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0325
    Cell Significance Index: -1.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0410
    Cell Significance Index: -8.6300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0414
    Cell Significance Index: -6.0200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0414
    Cell Significance Index: -3.0900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0448
    Cell Significance Index: -5.1300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0506
    Cell Significance Index: -2.5500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0537
    Cell Significance Index: -0.6100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0538
    Cell Significance Index: -6.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0713
    Cell Significance Index: -4.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0713
    Cell Significance Index: -1.8800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0722
    Cell Significance Index: -7.5200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0770
    Cell Significance Index: -6.1000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.0798
    Cell Significance Index: -1.1200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0838
    Cell Significance Index: -3.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0852
    Cell Significance Index: -6.5400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0870
    Cell Significance Index: -4.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0989
    Cell Significance Index: -6.6500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1152
    Cell Significance Index: -5.0100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1159
    Cell Significance Index: -1.2000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1160
    Cell Significance Index: -6.5100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1207
    Cell Significance Index: -7.4200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1280
    Cell Significance Index: -3.2900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1301
    Cell Significance Index: -1.9600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1419
    Cell Significance Index: -4.9300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1454
    Cell Significance Index: -3.8900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1486
    Cell Significance Index: -3.1100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1582
    Cell Significance Index: -4.6600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1605
    Cell Significance Index: -7.1000
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: -0.1700
    Cell Significance Index: -1.2300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1710
    Cell Significance Index: -3.1600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1711
    Cell Significance Index: -6.2800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** FOXO4 is a member of the forkhead box O (FOXO) family of transcription factors, which are known for their involvement in regulating cellular processes. FOXO4 is specifically characterized by its ability to bind to DNA and regulate the expression of target genes involved in cell cycle regulation, apoptosis, and metabolism. The protein is also known for its ability to interact with other proteins and signaling molecules, such as AKT and PI3K, to modulate its activity. **Pathways and Functions:** FOXO4 is involved in several signaling pathways, including: 1. **PI3K/AKT signaling pathway**: FOXO4 is phosphorylated by AKT, leading to its inhibition and degradation. This pathway is crucial for regulating cell survival, metabolism, and immune responses. 2. **DNA binding and transcriptional regulation**: FOXO4 binds to specific DNA sequences and regulates the expression of target genes involved in cell cycle regulation, apoptosis, and metabolism. 3. **Oxidative stress response**: FOXO4 is involved in regulating the expression of genes involved in oxidative stress response, such as antioxidant enzymes and DNA repair proteins. 4. **Metabolic regulation**: FOXO4 regulates the expression of genes involved in glucose metabolism, lipid metabolism, and energy homeostasis. FOXO4 has several functions, including: 1. **Cell cycle regulation**: FOXO4 regulates the expression of genes involved in cell cycle progression, including cyclin-dependent kinases and cyclin-dependent kinase inhibitors. 2. **Apoptosis regulation**: FOXO4 regulates the expression of genes involved in apoptosis, including pro-apoptotic and anti-apoptotic proteins. 3. **Metabolic regulation**: FOXO4 regulates the expression of genes involved in glucose metabolism, lipid metabolism, and energy homeostasis. 4. **Immune response regulation**: FOXO4 regulates the expression of genes involved in immune responses, including cytokines and chemokines. **Clinical Significance:** FOXO4 has been implicated in various diseases, including: 1. **Cancer**: FOXO4 is frequently downregulated in various types of cancer, including breast, lung, and colon cancer. Its downregulation is associated with poor prognosis and reduced survival rates. 2. **Metabolic disorders**: FOXO4 is involved in regulating glucose metabolism and energy homeostasis, making it a potential target for treating metabolic disorders, such as diabetes and obesity. 3. **Neurodegenerative diseases**: FOXO4 is involved in regulating cellular processes, including apoptosis and oxidative stress, making it a potential target for treating neurodegenerative diseases, such as Alzheimer's and Parkinson's. 4. **Immunological disorders**: FOXO4 regulates immune responses, making it a potential target for treating immunological disorders, such as autoimmune diseases and allergies. In conclusion, FOXO4 is a critical transcription factor involved in regulating various cellular processes, including cell cycle regulation, apoptosis, metabolism, and immune responses. Its dysregulation has been implicated in various diseases, making it a potential target for developing new therapeutic strategies.

Genular Protein ID: 2765268473

Symbol: FOXO4_HUMAN

Name: Forkhead box protein O4

UniProtKB Accession Codes:

P98177 B7WPJ7 O43821 Q13720 Q3KPF1 Q8TDK9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 9 Ensembl 2 EvolutionaryTrace 1 GO 34 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 9 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9341872

Title: AFX1 and p54nrb: fine mapping, genomic structure, and exclusion as candidate genes of X-linked dystonia parkinsonism.

PubMed ID: 9341872

DOI: 10.1007/s004390050553

PubMed ID: 9010221

Title: Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23).

PubMed ID: 9010221

DOI: 10.1038/sj.onc.1200814

PubMed ID: 11779849

Title: An mRNA splice variant of the AFX gene with altered transcriptional activity.

PubMed ID: 11779849

DOI: 10.1074/jbc.m106091200

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7529552

Title: Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family.

PubMed ID: 7529552

DOI: 10.1002/gcc.2870110203

PubMed ID: 10217147

Title: Direct control of the forkhead transcription factor AFX by protein kinase B.

PubMed ID: 10217147

DOI: 10.1038/19328

PubMed ID: 10518537

Title: Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B.

PubMed ID: 10518537

DOI: 10.1073/pnas.96.21.11836

PubMed ID: 10783894

Title: AFX-like forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1.

PubMed ID: 10783894

DOI: 10.1038/35008115

PubMed ID: 12761217

Title: The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism.

PubMed ID: 12761217

DOI: 10.1074/jbc.m302042200

PubMed ID: 15126506

Title: FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1).

PubMed ID: 15126506

DOI: 10.1074/jbc.m401138200

PubMed ID: 16114898

Title: 14-3-3 protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.

PubMed ID: 16114898

DOI: 10.1021/bi050618r

PubMed ID: 16054032

Title: Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin.

PubMed ID: 16054032

DOI: 10.1016/j.devcel.2005.05.017

PubMed ID: 16272144

Title: Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family.

PubMed ID: 16272144

DOI: 10.1093/jb/mvi146

PubMed ID: 15688030

Title: Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity.

PubMed ID: 15688030

DOI: 10.1038/sj.onc.1208352

PubMed ID: 16964248

Title: FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP.

PubMed ID: 16964248

DOI: 10.1038/ncb1469

PubMed ID: 20874444

Title: Oxidative stress-dependent regulation of Forkhead box O4 activity by nemo-like kinase.

PubMed ID: 20874444

DOI: 10.1089/ars.2010.3243

PubMed ID: 22972301

Title: Increased proteasome activity in human embryonic stem cells is regulated by PSMD11.

PubMed ID: 22972301

DOI: 10.1038/nature11468

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 10921784

Title: 1H, 13C and 15N resonance assignments of the DNA binding domain of the human forkhead transcription factor AFX.

PubMed ID: 10921784

DOI: 10.1023/a:1008358816478

PubMed ID: 11352721

Title: Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4).

PubMed ID: 11352721

DOI: 10.1021/bi001663w

Sequence Information:

  • Length: 505
  • Mass: 53684
  • Checksum: 0C71C8E2167CEE68
  • Sequence:
    • MDPGNENSAT EAAAIIDLDP DFEPQSRPRS CTWPLPRPEI ANQPSEPPEV EPDLGEKVHT 
EGRSEPILLP SRLPEPAGGP QPGILGAVTG PRKGGSRRNA WGNQSYAELI SQAIESAPEK 
RLTLAQIYEW MVRTVPYFKD KGDSNSSAGW KNSIRHNLSL HSKFIKVHNE ATGKSSWWML 
NPEGGKSGKA PRRRAASMDS SSKLLRGRSK APKKKPSVLP APPEGATPTS PVGHFAKWSG 
SPCSRNREEA DMWTTFRPRS SSNASSVSTR LSPLRPESEV LAEEIPASVS SYAGGVPPTL 
NEGLELLDGL NLTSSHSLLS RSGLSGFSLQ HPGVTGPLHT YSSSLFSPAE GPLSAGEGCF 
SSSQALEALL TSDTPPPPAD VLMTQVDPIL SQAPTLLLLG GLPSSSKLAT GVGLCPKPLE 
APGPSSLVPT LSMIAPPPVM ASAPIPKALG TPVLTPPTEA ASQDRMPQDL DLDMYMENLE 
CDMDNIISDL MDEGEGLDFN FEPDP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.