Details for: MYBL2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 27.6767
Cell Significance Index: -7.0200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 16.2951
Cell Significance Index: -6.6200 - Cell Name: colon endothelial cell (CL1001572)
Fold Change: 10.8226
Cell Significance Index: 8.2600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 5.0691
Cell Significance Index: -6.2500 - Cell Name: centroblast (CL0009112)
Fold Change: 4.7791
Cell Significance Index: 11.1500 - Cell Name: germ cell (CL0000586)
Fold Change: 4.0533
Cell Significance Index: 30.6100 - Cell Name: basophilic erythroblast (CL0000549)
Fold Change: 3.9306
Cell Significance Index: 1.7900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.6571
Cell Significance Index: 195.4200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.2337
Cell Significance Index: -2.7000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.1469
Cell Significance Index: 30.6800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.9677
Cell Significance Index: 95.7300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6975
Cell Significance Index: 113.4400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6279
Cell Significance Index: 68.3000 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.6200
Cell Significance Index: 6.7400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5607
Cell Significance Index: 33.6600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4435
Cell Significance Index: 88.0200 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.4024
Cell Significance Index: 10.2800 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.3716
Cell Significance Index: 6.2500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.3214
Cell Significance Index: 37.4600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.3163
Cell Significance Index: 10.9900 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 0.2642
Cell Significance Index: 2.2700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1857
Cell Significance Index: 5.1900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1728
Cell Significance Index: 4.9800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1413
Cell Significance Index: 77.1700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1400
Cell Significance Index: 2.9300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1312
Cell Significance Index: 7.3600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1056
Cell Significance Index: 1.8100 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.0869
Cell Significance Index: 1.2200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0666
Cell Significance Index: 29.4500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0603
Cell Significance Index: 4.1700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0421
Cell Significance Index: 1.3500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0416
Cell Significance Index: 1.0400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0387
Cell Significance Index: 6.6000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0359
Cell Significance Index: 32.4600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0306
Cell Significance Index: 1.9800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0287
Cell Significance Index: 1.0100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0249
Cell Significance Index: 0.5300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0134
Cell Significance Index: 0.2900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0099
Cell Significance Index: 1.2200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0059
Cell Significance Index: 0.1300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0043
Cell Significance Index: 0.2000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0012
Cell Significance Index: 0.8000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0011
Cell Significance Index: 0.0300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0005
Cell Significance Index: 0.1100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0014
Cell Significance Index: -2.6200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0021
Cell Significance Index: -0.0600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0025
Cell Significance Index: -0.4700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0036
Cell Significance Index: -6.7200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0046
Cell Significance Index: -7.1500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0066
Cell Significance Index: -8.9500 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -0.0083
Cell Significance Index: -0.0600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0087
Cell Significance Index: -6.6000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0089
Cell Significance Index: -6.5700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0096
Cell Significance Index: -6.0800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0096
Cell Significance Index: -3.4400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0099
Cell Significance Index: -7.2600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0114
Cell Significance Index: -7.1200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0121
Cell Significance Index: -6.8300 - Cell Name: salivary gland cell (CL0009005)
Fold Change: -0.0129
Cell Significance Index: -0.1600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0158
Cell Significance Index: -7.1600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0185
Cell Significance Index: -5.3200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0244
Cell Significance Index: -4.3900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0245
Cell Significance Index: -0.4100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0247
Cell Significance Index: -3.3900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0287
Cell Significance Index: -3.7100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0337
Cell Significance Index: -7.0900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0353
Cell Significance Index: -5.1300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0378
Cell Significance Index: -4.3300 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0396
Cell Significance Index: -0.4100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0452
Cell Significance Index: -4.6200 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0461
Cell Significance Index: -0.6600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0675
Cell Significance Index: -7.0300 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0696
Cell Significance Index: -0.8800 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0718
Cell Significance Index: -0.9100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0719
Cell Significance Index: -1.0300 - Cell Name: late promyelocyte (CL0002151)
Fold Change: -0.0724
Cell Significance Index: -0.4800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0763
Cell Significance Index: -5.4000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0778
Cell Significance Index: -1.9400 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.0826
Cell Significance Index: -1.0400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0852
Cell Significance Index: -6.5400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0856
Cell Significance Index: -1.2900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0939
Cell Significance Index: -4.8800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1008
Cell Significance Index: -7.5100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1010
Cell Significance Index: -6.2100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1019
Cell Significance Index: -6.8500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1056
Cell Significance Index: -5.5000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1066
Cell Significance Index: -1.6500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1167
Cell Significance Index: -7.3600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1204
Cell Significance Index: -5.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1267
Cell Significance Index: -7.7700 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.1426
Cell Significance Index: -2.0000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1501
Cell Significance Index: -6.6400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1538
Cell Significance Index: -4.5300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1576
Cell Significance Index: -4.0500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1720
Cell Significance Index: -6.0300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1724
Cell Significance Index: -8.0400 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.1725
Cell Significance Index: -1.0800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1748
Cell Significance Index: -6.6200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1837
Cell Significance Index: -4.8300 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1883
Cell Significance Index: -4.5600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 844353820
Symbol: MYBB_HUMAN
Name: Myb-related protein B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3060855
Title: Isolation of human cDNA clones of myb-related genes, A-myb and B-myb.
PubMed ID: 3060855
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9840932
Title: The cell-cycle regulated transcription factor B-Myb is phosphorylated by cyclin A/Cdk2 at sites that enhance its transactivation properties.
PubMed ID: 9840932
PubMed ID: 10095772
Title: Identification of cyclin A/Cdk2 phosphorylation sites in B-Myb.
PubMed ID: 10095772
PubMed ID: 10770937
Title: Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB.
PubMed ID: 10770937
PubMed ID: 8062924
Title: Multiple nuclear localization signals of the B-myb gene product.
PubMed ID: 8062924
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17671431
Title: LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes.
PubMed ID: 17671431
DOI: 10.4161/cc.6.15.4512
PubMed ID: 17531812
Title: Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.
PubMed ID: 17531812
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25557911
Title: Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.
PubMed ID: 25557911
DOI: 10.1038/ncomms6800
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 700
- Mass: 78764
- Checksum: D91B28B3DAB94061
- Sequence:
MSRRTRCEDL DELHYQDTDS DVPEQRDSKC KVKWTHEEDE QLRALVRQFG QQDWKFLASH FPNRTDQQCQ YRWLRVLNPD LVKGPWTKEE DQKVIELVKK YGTKQWTLIA KHLKGRLGKQ CRERWHNHLN PEVKKSCWTE EEDRIICEAH KVLGNRWAEI AKMLPGRTDN AVKNHWNSTI KRKVDTGGFL SESKDCKPPV YLLLELEDKD GLQSAQPTEG QGSLLTNWPS VPPTIKEEEN SEEELAAATT SKEQEPIGTD LDAVRTPEPL EEFPKREDQE GSPPETSLPY KWVVEAANLL IPAVGSSLSE ALDLIESDPD AWCDLSKFDL PEEPSAEDSI NNSLVQLQAS HQQQVLPPRQ PSALVPSVTE YRLDGHTISD LSRSSRGELI PISPSTEVGG SGIGTPPSVL KRQRKRRVAL SPVTENSTSL SFLDSCNSLT PKSTPVKTLP FSPSQFLNFW NKQDTLELES PSLTSTPVCS QKVVVTTPLH RDKTPLHQKH AAFVTPDQKY SMDNTPHTPT PFKNALEKYG PLKPLPQTPH LEEDLKEVLR SEAGIELIIE DDIRPEKQKR KPGLRRSPIK KVRKSLALDI VDEDVKLMMS TLPKSLSLPT TAPSNSSSLT LSGIKEDNSL LNQGFLQAKP EKAAVAQKPR SHFTTPAPMS SAWKTVACGG TRDQLFMQEK ARQLLGRLKP SHTSRTLILS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.