Details for: NEFM
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 6.5311
Cell Significance Index: -20.0600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.7856
Cell Significance Index: 61.0000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.4023
Cell Significance Index: 126.1300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.1474
Cell Significance Index: 61.2800 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 1.6867
Cell Significance Index: 17.5700 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.0184
Cell Significance Index: 6.7600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9241
Cell Significance Index: 185.3700 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.7992
Cell Significance Index: 6.1600 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.7888
Cell Significance Index: 6.0500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.6103
Cell Significance Index: 41.0400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.6049
Cell Significance Index: 70.5000 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.3769
Cell Significance Index: 4.7000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2464
Cell Significance Index: 12.8000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2071
Cell Significance Index: 12.7300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1822
Cell Significance Index: 8.0600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.1794
Cell Significance Index: 6.8000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1195
Cell Significance Index: 42.8600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.0875
Cell Significance Index: 1.8700 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: 0.0654
Cell Significance Index: 0.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0332
Cell Significance Index: 5.9900 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.0230
Cell Significance Index: 0.1900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0214
Cell Significance Index: 14.7900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0019
Cell Significance Index: -1.0600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0067
Cell Significance Index: -4.1900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0070
Cell Significance Index: -5.2200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0104
Cell Significance Index: -19.5100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0119
Cell Significance Index: -21.9300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0142
Cell Significance Index: -21.9300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0151
Cell Significance Index: -2.0800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0209
Cell Significance Index: -15.3000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0262
Cell Significance Index: -4.4700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0263
Cell Significance Index: -19.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0276
Cell Significance Index: -17.5400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0314
Cell Significance Index: -1.7600 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0335
Cell Significance Index: -18.3200 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.0381
Cell Significance Index: -0.5900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0385
Cell Significance Index: -17.0200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0420
Cell Significance Index: -19.0500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0452
Cell Significance Index: -9.5200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0513
Cell Significance Index: -14.7700 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0537
Cell Significance Index: -2.3400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0571
Cell Significance Index: -7.3300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0777
Cell Significance Index: -9.5600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0998
Cell Significance Index: -11.3900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1011
Cell Significance Index: -20.0700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1186
Cell Significance Index: -17.2400 - Cell Name: neural cell (CL0002319)
Fold Change: -0.1234
Cell Significance Index: -1.4400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1420
Cell Significance Index: -18.3400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1557
Cell Significance Index: -15.9000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1615
Cell Significance Index: -10.1800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1637
Cell Significance Index: -19.3000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1713
Cell Significance Index: -19.6300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.1766
Cell Significance Index: -2.1900 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -0.1860
Cell Significance Index: -1.2100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1877
Cell Significance Index: -19.5400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.1897
Cell Significance Index: -2.5300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1908
Cell Significance Index: -4.0500 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1955
Cell Significance Index: -2.1300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2006
Cell Significance Index: -4.8100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2129
Cell Significance Index: -6.7800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2217
Cell Significance Index: -3.7100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2226
Cell Significance Index: -17.6300 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.2316
Cell Significance Index: -1.4500 - Cell Name: neuron (CL0000540)
Fold Change: -0.2326
Cell Significance Index: -2.2100 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.2564
Cell Significance Index: -6.2100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2674
Cell Significance Index: -19.9300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2730
Cell Significance Index: -19.3100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2828
Cell Significance Index: -9.2600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2966
Cell Significance Index: -10.3900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3050
Cell Significance Index: -14.3400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3062
Cell Significance Index: -8.5600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3341
Cell Significance Index: -9.8400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3373
Cell Significance Index: -5.7800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.3923
Cell Significance Index: -17.7800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.4043
Cell Significance Index: -10.0900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4137
Cell Significance Index: -11.0900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.4252
Cell Significance Index: -8.9000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4255
Cell Significance Index: -15.6200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4420
Cell Significance Index: -15.3600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.4450
Cell Significance Index: -20.7500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5123
Cell Significance Index: -10.1300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.5279
Cell Significance Index: -18.5500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.5285
Cell Significance Index: -10.6100 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.5329
Cell Significance Index: -13.3100 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.5384
Cell Significance Index: -5.9400 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: -0.5460
Cell Significance Index: -4.8100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.5478
Cell Significance Index: -6.5300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5548
Cell Significance Index: -17.7700 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.5738
Cell Significance Index: -14.3100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.5757
Cell Significance Index: -7.8600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.5917
Cell Significance Index: -12.3500 - Cell Name: enteric neuron (CL0007011)
Fold Change: -0.6025
Cell Significance Index: -4.3600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6241
Cell Significance Index: -16.4100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6344
Cell Significance Index: -18.1900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.6436
Cell Significance Index: -13.9100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.6494
Cell Significance Index: -9.3000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.6526
Cell Significance Index: -20.6400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.6596
Cell Significance Index: -17.6500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.6640
Cell Significance Index: -19.5000 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.6714
Cell Significance Index: -8.9500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2558696816
Symbol: NFM_HUMAN
Name: Neurofilament medium polypeptide
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3608989
Title: The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family.
PubMed ID: 3608989
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2450354
Title: Identification of the major multiphosphorylation site in mammalian neurofilaments.
PubMed ID: 2450354
PubMed ID: 8621664
Title: PKN associates and phosphorylates the head-rod domain of neurofilament protein.
PubMed ID: 8621664
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 916
- Mass: 102472
- Checksum: 187B16CA6C6BF092
- Sequence:
MSYTLDSLGN PSAYRRVTET RSSFSRVSGS PSSGFRSQSW SRGSPSTVSS SYKRSMLAPR LAYSSAMLSS AESSLDFSQS SSLLNGGSGP GGDYKLSRSN EKEQLQGLND RFAGYIEKVH YLEQQNKEIE AEIQALRQKQ ASHAQLGDAY DQEIRELRAT LEMVNHEKAQ VQLDSDHLEE DIHRLKERFE EEARLRDDTE AAIRALRKDI EEASLVKVEL DKKVQSLQDE VAFLRSNHEE EVADLLAQIQ ASHITVERKD YLKTDISTAL KEIRSQLESH SDQNMHQAEE WFKCRYAKLT EAAEQNKEAI RSAKEEIAEY RRQLQSKSIE LESVRGTKES LERQLSDIEE RHNHDLSSYQ DTIQQLENEL RGTKWEMARH LREYQDLLNV KMALDIEIAA YRKLLEGEET RFSTFAGSIT GPLYTHRPPI TISSKIQKPK VEAPKLKVQH KFVEEIIEET KVEDEKSEME EALTAITEEL AVSMKEEKKE AAEEKEEEPE AEEEEVAAKK SPVKATAPEV KEEEGEKEEE EGQEEEEEED EGAKSDQAEE GGSEKEGSSE KEEGEQEEGE TEAEAEGEEA EAKEEKKVEE KSEEVATKEE LVADAKVEKP EKAKSPVPKS PVEEKGKSPV PKSPVEEKGK SPVPKSPVEE KGKSPVPKSP VEEKGKSPVS KSPVEEKAKS PVPKSPVEEA KSKAEVGKGE QKEEEEKEVK EAPKEEKVEK KEEKPKDVPE KKKAESPVKE EAVAEVVTIT KSVKVHLEKE TKEEGKPLQQ EKEKEKAGGE GGSEEEGSDK GAKGSRKEDI AVNGEVEGKE EVEQETKEKG SGREEEKGVV TNGLDLSPAD EKKGGDKSEE KVVVTKTVEK ITSEGGDGAT KYITKSVTVT QKVEEHEETF EEKLVSTKKV EKVTSHAIVK EVTQSD
Genular Protein ID: 2388031198
Symbol: Q9UK51_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 260
- Mass: 28427
- Checksum: AFA61CA51A802448
- Sequence:
KTKVEAPKLK VQHKFVEEII EETKVEDEKS EMEEALTAIT EELAVSMKEE KKEAAEEKEE EPEAEEEEVA AKKSPVKATA PEVKEEEGEK EEEEGQEEEE EEDEGAKSDQ AEEGGSEKEG SSEKEEGEQE EGETEAEAEG EEAEAKEEKK VEEKSEEVAT KEELVADAKV EKPEKAKSPV PKSPVEEKGK SPVPKSPVEE KGKSPVPKSP VEEKGKSPVP KSPVEEKGKS PVSKSPVEEK AKSPVPKSPV EEAKSKAEVG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.