Details for: OXA1L

Gene ID: 5018

Symbol: OXA1L

Ensembl ID: ENSG00000155463

Description: OXA1L mitochondrial inner membrane protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 195.5058
    Cell Significance Index: -30.4100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 88.5646
    Cell Significance Index: -35.9800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 85.1984
    Cell Significance Index: -21.6100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 80.5511
    Cell Significance Index: -38.0300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 77.5878
    Cell Significance Index: -39.9100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 57.0920
    Cell Significance Index: -38.3100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.3559
    Cell Significance Index: -36.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.3036
    Cell Significance Index: -36.1300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.1797
    Cell Significance Index: -27.2700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.9757
    Cell Significance Index: -30.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.5463
    Cell Significance Index: -37.6700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.7291
    Cell Significance Index: -10.3500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 2.9003
    Cell Significance Index: 31.5300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.5156
    Cell Significance Index: 73.8800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.4394
    Cell Significance Index: 51.0600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.9462
    Cell Significance Index: 116.8400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.9319
    Cell Significance Index: 15.4300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.7003
    Cell Significance Index: 21.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.6786
    Cell Significance Index: 197.9600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.4520
    Cell Significance Index: 19.8100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.4168
    Cell Significance Index: 91.4100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.1594
    Cell Significance Index: 159.2200
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.1068
    Cell Significance Index: 16.8100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.0394
    Cell Significance Index: 19.2100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9225
    Cell Significance Index: 25.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9016
    Cell Significance Index: 814.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.8587
    Cell Significance Index: 22.5800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.8577
    Cell Significance Index: 110.8100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.8189
    Cell Significance Index: 38.1800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7976
    Cell Significance Index: 17.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7873
    Cell Significance Index: 55.6800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7590
    Cell Significance Index: 93.3200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.7369
    Cell Significance Index: 19.7500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.7258
    Cell Significance Index: 25.2200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6993
    Cell Significance Index: 309.1900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.6891
    Cell Significance Index: 117.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6648
    Cell Significance Index: 119.8400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6331
    Cell Significance Index: 125.6500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6094
    Cell Significance Index: 45.4200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5955
    Cell Significance Index: 325.2400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5215
    Cell Significance Index: 27.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4908
    Cell Significance Index: 13.3600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.4872
    Cell Significance Index: 5.5400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.4479
    Cell Significance Index: 7.9200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4099
    Cell Significance Index: 21.3500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4095
    Cell Significance Index: 52.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4084
    Cell Significance Index: 21.4400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3931
    Cell Significance Index: 11.3300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3204
    Cell Significance Index: 60.9800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3113
    Cell Significance Index: 50.6300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2872
    Cell Significance Index: 13.5000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2553
    Cell Significance Index: 16.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2064
    Cell Significance Index: 41.4000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1919
    Cell Significance Index: 8.7000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1848
    Cell Significance Index: 5.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1063
    Cell Significance Index: 38.1300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0994
    Cell Significance Index: 2.6600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0509
    Cell Significance Index: 1.0900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0503
    Cell Significance Index: 4.9800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0321
    Cell Significance Index: 24.3000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0245
    Cell Significance Index: 0.4100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0048
    Cell Significance Index: 0.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0007
    Cell Significance Index: 1.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0009
    Cell Significance Index: -0.0900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0077
    Cell Significance Index: -5.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0098
    Cell Significance Index: -6.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0105
    Cell Significance Index: -7.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0141
    Cell Significance Index: -25.9900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0235
    Cell Significance Index: -36.1100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0302
    Cell Significance Index: -41.0000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0348
    Cell Significance Index: -22.0900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0457
    Cell Significance Index: -25.7900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0478
    Cell Significance Index: -1.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0494
    Cell Significance Index: -1.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0640
    Cell Significance Index: -29.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0856
    Cell Significance Index: -18.0200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0947
    Cell Significance Index: -10.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1189
    Cell Significance Index: -34.2000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1627
    Cell Significance Index: -1.9400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1839
    Cell Significance Index: -21.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1840
    Cell Significance Index: -26.7500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1878
    Cell Significance Index: -14.4100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1933
    Cell Significance Index: -4.4700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2293
    Cell Significance Index: -26.1800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2302
    Cell Significance Index: -2.1200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2788
    Cell Significance Index: -6.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3510
    Cell Significance Index: -36.5500
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.3530
    Cell Significance Index: -2.2100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3664
    Cell Significance Index: -20.5600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3672
    Cell Significance Index: -24.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4203
    Cell Significance Index: -33.2900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4376
    Cell Significance Index: -4.5300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4772
    Cell Significance Index: -29.3300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5099
    Cell Significance Index: -31.2600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5306
    Cell Significance Index: -7.9500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.5314
    Cell Significance Index: -26.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5695
    Cell Significance Index: -14.6400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.5882
    Cell Significance Index: -10.1400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.6070
    Cell Significance Index: -17.4000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.6494
    Cell Significance Index: -4.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The OXA1L gene is a mitochondrial inner membrane protein that is encoded by the ENSG00000155463 gene. It exhibits a high degree of sequence homology with other mitochondrial proteins, including those involved in the assembly and function of the ATP synthase complex. The OXA1L protein is characterized by its ability to bind to other proteins, including those involved in the regulation of protein translation and transcription. Furthermore, OXA1L has been shown to interact with other mitochondrial proteins, including those involved in the regulation of the mitochondrial membrane potential. **Pathways and Functions:** The OXA1L gene is involved in several key pathways, including: 1. **Aerobic Respiration:** OXA1L plays a crucial role in the assembly and function of the ATP synthase complex, which is essential for the production of ATP during aerobic respiration. 2. **Membrane Insertase Activity:** OXA1L has been shown to interact with other proteins involved in the insertion of proteins into the mitochondrial inner membrane. 3. **Metabolism of Proteins:** OXA1L is involved in the regulation of protein translation and transcription, which are essential for the maintenance of cellular homeostasis. 4. **Mitochondrial Inner Membrane:** OXA1L is a key component of the mitochondrial inner membrane, where it interacts with other proteins involved in the regulation of the mitochondrial membrane potential. **Clinical Significance:** The OXA1L gene has been implicated in various diseases, including: 1. **Immune-Mediated Disorders:** OXA1L has been shown to play a crucial role in the regulation of immune cell function, particularly in the context of autoimmune diseases. 2. **Mitochondrial Disorders:** OXA1L has been implicated in the pathogenesis of mitochondrial disorders, including those caused by mutations in the ATP synthase complex. 3. **Cancer:** OXA1L has been shown to be overexpressed in certain types of cancer, suggesting its potential role in tumorigenesis. In conclusion, the OXA1L gene is a critical component of the mitochondrial respiratory chain, and its dysregulation has been implicated in various diseases. Further research is needed to fully elucidate the role of OXA1L in immune function and cellular metabolism, and to explore its potential as a therapeutic target for the treatment of diseases associated with mitochondrial dysfunction. **Implications for Immunology:** The OXA1L gene has significant implications for our understanding of immune function and the regulation of cellular metabolism. The OXA1L protein's involvement in the regulation of protein translation and transcription suggests its potential role in the modulation of immune cell function. Furthermore, the OXA1L gene's association with immune-mediated disorders highlights the importance of mitochondrial function in maintaining immune homeostasis. Further research is needed to explore the role of OXA1L in the regulation of immune cell function and to explore its potential as a therapeutic target for the treatment of immune-mediated disorders. **Implications for Cancer Research:** The OXA1L gene's association with cancer suggests its potential role in tumorigenesis. The OXA1L protein's involvement in the regulation of protein translation and transcription suggests its potential role in the modulation of cancer cell function. Furthermore, the OXA1L gene's overexpression in certain types of cancer highlights the importance of mitochondrial function in maintaining cancer cell homeostasis. Further research is needed to explore the role of OXA1L in cancer development and to explore its potential as a therapeutic target for the treatment of cancer. In summary, the OXA1L gene is a critical component of the mitochondrial respiratory chain, and its dysregulation has been implicated in various diseases. Further research is needed to fully elucidate the role of OXA1L in immune function and cellular metabolism, and to explore its potential as a therapeutic target for the treatment of diseases associated with mitochondrial dysfunction.

Genular Protein ID: 968346786

Symbol: OXA1L_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q15070 A0A087X0L7 B4DPA2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EMDB 2 Ensembl 2 ExpressionAtlas 1 GO 16 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 4 RefSeq 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TCDB 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7991568

Title: Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae.

PubMed ID: 7991568

DOI: 10.1073/pnas.91.25.11978

PubMed ID: 9247084

Title: Sequence and structure of the human OXA1L gene and its upstream elements.

PubMed ID: 9247084

DOI: 10.1016/s0925-4439(97)00031-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17936786

Title: Knockdown of human Oxa1l impairs the biogenesis of F1Fo-ATP synthase and NADH:ubiquinone oxidoreductase.

PubMed ID: 17936786

DOI: 10.1016/j.jmb.2007.09.044

PubMed ID: 20601428

Title: Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes.

PubMed ID: 20601428

DOI: 10.1074/jbc.m110.148262

PubMed ID: 20739282

Title: Identification of protein-protein and protein-ribosome interacting regions of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L.

PubMed ID: 20739282

DOI: 10.1074/jbc.m110.163808

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30201738

Title: OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.

PubMed ID: 30201738

DOI: 10.15252/emmm.201809060

PubMed ID: 38199007

Title: Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria.

PubMed ID: 38199007

DOI: 10.1016/j.molcel.2023.12.013

PubMed ID: 33243891

Title: Elongational stalling activates mitoribosome-associated quality control.

PubMed ID: 33243891

DOI: 10.1126/science.abc7782

PubMed ID: 33602856

Title: Mechanism of membrane-tethered mitochondrial protein synthesis.

PubMed ID: 33602856

DOI: 10.1126/science.abe0763

Sequence Information:

  • Length: 435
  • Mass: 48520
  • Checksum: B346B35346ACA675
  • Sequence:
    • MAMGLMCGRR ELLRLLQSGR RVHSVAGPSQ WLGKPLTTRL LFPAAPCCCR PHYLFLAASG 
PRSLSTSAIS FAEVQVQAPP VVAATPSPTA VPEVASGETA DVVQTAAEQS FAELGLGSYT 
PVGLIQNLLE FMHVDLGLPW WGAIAACTVF ARCLIFPLIV TGQREAARIH NHLPEIQKFS 
SRIREAKLAG DHIEYYKASS EMALYQKKHG IKLYKPLILP VTQAPIFISF FIALREMANL 
PVPSLQTGGL WWFQDLTVSD PIYILPLAVT ATMWAVLELG AETGVQSSDL QWMRNVIRMM 
PLITLPITMH FPTAVFMYWL SSNLFSLVQV SCLRIPAVRT VLKIPQRVVH DLDKLPPREG 
FLESFKKGWK NAEMTRQLRE REQRMRNQLE LAARGPLRQT FTHNPLLQPG KDNPPNIPSS 
SSKPKSKYPW HDTLG

Genular Protein ID: 1584135688

Symbol: J3KNA0_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KNA0

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 GeneTree 1 HGNC 1 InterPro 2 KEGG 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 2 SMR 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 495
  • Mass: 55270
  • Checksum: 90D4CDD582F750B1
  • Sequence:
    • MVTWLYRFLP TSNMAAKLRS LLPPDLRLQF WLHARLQKCF LSRGCGSYCA GAKASPLPGK 
MAMGLMCGRR ELLRLLQSGR RVHSVAGPSQ WLGKPLTTRL LFPAAPCCCR PHYLFLAASG 
PRSLSTSAIS FAEVQVQAPP VVAATPSPTA VPEVASGETA DVVQTAAEQS FAELGLGSYT 
PVGLIQNLLE FMHVDLGLPW WGAIAACTVF ARCLIFPLIV TGQREAARIH NHLPEIQKFS 
SRIREAKLAG DHIEYYKASS EMALYQKKHG IKLYKPLILP VTQAPIFISF FIALREMANL 
PVPSLQTGGL WWFQDLTVSD PIYILPLAVT ATMWAVLELG AETGVQSSDL QWMRNVIRMM 
PLITLPITMH FPTAVFMYWL SSNLFSLVQV SCLRIPAVRT VLKIPQRVVH DLDKLPPREG 
FLESFKKGWK NAEMTRQLRE REQRMRNQLE LAARGPLRQT FTHNPLLQPG KDNPPNIPSS 
SSKPKSKYPW HDTLG

Genular Protein ID: 3665949509

Symbol: Q2M1J6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2M1J6

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 Pfam 2 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 496
  • Mass: 55385
  • Checksum: 8C46271F2083728A
  • Sequence:
    • MVTWLYRFLP TSNMAAKLRS LLPPDLRLQF WLHARLQKCF LSRGCGSYCA GAKASPLPGK 
MAMGLMCGRR ELLRLLQSGR RVHSVAGPSQ WLGKPLTTRL LFPVAPCCCR PHYLFLAASG 
PRSLSTSAIS FAEVQVQAPP VVAATPSPTA VPEVASGETA DVVQTAAEQS FAELGLGSYT 
PVGLIQNLLE FMHVDLGLPW WGAIAACTVF ARCLIFPLIV TGQREAARIH NHLPEIQKFS 
SRIREAKLAG DHIEYYKASS EMALYQKKHG IKLYKPLILP VTQAPIFISF FIALREMANL 
PVPSLQTGGL WWFQDLTVSD PIYILPLAVT ATMWAVLELG AETGVQSSDL QWMRNVIRMM 
PLITLPITMH FPTAVFMYWL SSNLFSLVQV SCLRIPAVRT VLKIPQRVVH DLDKLPPREG 
FLESFKKGWK NAEMTRQLRE REQRMRNQLE LAARGPLRQT FTHNPLLQPG KDNPPNIPSS 
SSSKPKSKYP WHDTLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.