Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epithelial cell of thymus (CL0002293)
Fold Change: 7.1164
Cell Significance Index: 54.7200 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 6.6502
Cell Significance Index: 55.0000 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.8956
Cell Significance Index: 15.3100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.6261
Cell Significance Index: 13.1100 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.5969
Cell Significance Index: 9.4700 - Cell Name: colon endothelial cell (CL1001572)
Fold Change: 0.5765
Cell Significance Index: 0.4400 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.4896
Cell Significance Index: 5.0500 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.1536
Cell Significance Index: 1.6800 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 0.1211
Cell Significance Index: 1.1000 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.0077
Cell Significance Index: 0.0800 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.0031
Cell Significance Index: 0.0300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: 0.0027
Cell Significance Index: 0.1100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0015
Cell Significance Index: -2.7500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0019
Cell Significance Index: -0.8800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0028
Cell Significance Index: -1.6000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0029
Cell Significance Index: -2.1300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0032
Cell Significance Index: -0.5500 - Cell Name: chondroblast (CL0000058)
Fold Change: -0.0034
Cell Significance Index: -0.0200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0036
Cell Significance Index: -2.7600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0049
Cell Significance Index: -0.1600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0087
Cell Significance Index: -2.5100 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.0100
Cell Significance Index: -0.2000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0132
Cell Significance Index: -2.6500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0148
Cell Significance Index: -1.6900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0154
Cell Significance Index: -0.2200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0170
Cell Significance Index: -2.3400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0183
Cell Significance Index: -0.9500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0184
Cell Significance Index: -2.1500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.0188
Cell Significance Index: -0.2700 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0229
Cell Significance Index: -0.3000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0258
Cell Significance Index: -3.3300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0323
Cell Significance Index: -0.8800 - Cell Name: osteoblast (CL0000062)
Fold Change: -0.0330
Cell Significance Index: -0.3200 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.0343
Cell Significance Index: -0.4700 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.0363
Cell Significance Index: -0.4700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0370
Cell Significance Index: -1.3600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0385
Cell Significance Index: -2.5900 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.0414
Cell Significance Index: -0.8100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0431
Cell Significance Index: -1.2000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0435
Cell Significance Index: -3.2400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0478
Cell Significance Index: -2.4900 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.0498
Cell Significance Index: -0.4800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0527
Cell Significance Index: -2.9600 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0533
Cell Significance Index: -1.0500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.0543
Cell Significance Index: -0.5900 - Cell Name: tendon cell (CL0000388)
Fold Change: -0.0544
Cell Significance Index: -0.7400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0549
Cell Significance Index: -2.4900 - Cell Name: neutrophil (CL0000775)
Fold Change: -0.0560
Cell Significance Index: -0.7000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0578
Cell Significance Index: -1.5500 - Cell Name: muscle fibroblast (CL1001609)
Fold Change: -0.0588
Cell Significance Index: -0.3600 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: -0.0605
Cell Significance Index: -0.7000 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0615
Cell Significance Index: -1.0600 - Cell Name: stromal cell (CL0000499)
Fold Change: -0.0646
Cell Significance Index: -0.6600 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: -0.0648
Cell Significance Index: -0.4300 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0649
Cell Significance Index: -1.6200 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0673
Cell Significance Index: -1.0800 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0681
Cell Significance Index: -0.8600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0697
Cell Significance Index: -3.2800 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0710
Cell Significance Index: -0.9000 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: -0.0712
Cell Significance Index: -0.8600 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: -0.0724
Cell Significance Index: -0.8200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0730
Cell Significance Index: -0.8300 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0777
Cell Significance Index: -1.9800 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.0780
Cell Significance Index: -1.0400 - Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.0784
Cell Significance Index: -1.2700 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.0794
Cell Significance Index: -1.0700 - Cell Name: granulocyte (CL0000094)
Fold Change: -0.0796
Cell Significance Index: -0.9600 - Cell Name: promyelocyte (CL0000836)
Fold Change: -0.0809
Cell Significance Index: -0.8000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0832
Cell Significance Index: -2.4500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0841
Cell Significance Index: -2.4000 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: -0.0876
Cell Significance Index: -0.8900 - Cell Name: myelocyte (CL0002193)
Fold Change: -0.0889
Cell Significance Index: -0.9500 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.0908
Cell Significance Index: -0.9400 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: -0.0927
Cell Significance Index: -0.9600 - Cell Name: myoblast (CL0000056)
Fold Change: -0.0957
Cell Significance Index: -0.9400 - Cell Name: stem cell (CL0000034)
Fold Change: -0.0991
Cell Significance Index: -0.7200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0994
Cell Significance Index: -2.4800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1004
Cell Significance Index: -2.6400 - Cell Name: promonocyte (CL0000559)
Fold Change: -0.1021
Cell Significance Index: -1.0900 - Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
Fold Change: -0.1039
Cell Significance Index: -1.0500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1048
Cell Significance Index: -3.0100 - Cell Name: unswitched memory B cell (CL0000970)
Fold Change: -0.1052
Cell Significance Index: -0.9400 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: -0.1062
Cell Significance Index: -1.1000 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: -0.1067
Cell Significance Index: -1.1100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1101
Cell Significance Index: -2.9400 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1114
Cell Significance Index: -2.4400 - Cell Name: early promyelocyte (CL0002154)
Fold Change: -0.1144
Cell Significance Index: -0.7300 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1160
Cell Significance Index: -2.8100 - Cell Name: neuroplacodal cell (CL0000032)
Fold Change: -0.1169
Cell Significance Index: -1.4400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1183
Cell Significance Index: -2.5100 - Cell Name: Schwann cell precursor (CL0002375)
Fold Change: -0.1183
Cell Significance Index: -0.9400 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.1190
Cell Significance Index: -1.6500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1201
Cell Significance Index: -2.8800 - Cell Name: peridermal cell (CL0000078)
Fold Change: -0.1219
Cell Significance Index: -0.7600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.1221
Cell Significance Index: -2.9800 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: -0.1224
Cell Significance Index: -1.0900 - Cell Name: megakaryocyte progenitor cell (CL0000553)
Fold Change: -0.1238
Cell Significance Index: -0.8900 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: -0.1244
Cell Significance Index: -1.1100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1253
Cell Significance Index: -2.6000 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: -0.1262
Cell Significance Index: -1.4700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 219614069
Symbol: PAX1_HUMAN
Name: Paired box protein Pax-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2501086
Title: Conservation of the paired domain in metazoans and its structure in three isolated human genes.
PubMed ID: 2501086
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 8863157
Title: PAX genes and human neural tube defects: an amino acid substitution in PAX1 in a patient with spina bifida.
PubMed ID: 8863157
DOI: 10.1136/jmg.33.8.655
PubMed ID: 23851939
Title: A hypofunctional PAX1 mutation causes autosomal recessively inherited otofaciocervical syndrome.
PubMed ID: 23851939
Sequence Information:
- Length: 534
- Mass: 55499
- Checksum: 6B06A2AD302FDEEA
- Sequence:
MKFTLGLGSR AWRVSWEGAA AAAAGPGAGG SALRCRAQRV SSPRLGRRGS RLSGALPLCL SRGGGGAQAL PDCAGPSPGH PGHPGARQLA GPLAMEQTYG EVNQLGGVFV NGRPLPNAIR LRIVELAQLG IRPCDISRQL RVSHGCVSKI LARYNETGSI LPGAIGGSKP RVTTPNVVKH IRDYKQGDPG IFAWEIRDRL LADGVCDKYN VPSVSSISRI LRNKIGSLAQ PGPYEASKQP PSQPTLPYNH IYQYPYPSPV SPTGAKMGSH PGVPGTAGHV SIPRSWPSAH SVSNILGIRT FMEQTGALAG SEGTAYSPKM EDWAGVNRTA FPATPAVNGL EKPALEADIK YTQSASTLSA VGGFLPACAY PASNQHGVYS APGGGYLAPG PPWPPAQGPP LAPPGAGVAV HGGELAAAMT FKHPSREGSL PAPAARPRTP SVAYTDCPSR PRPPRGSSPR TRARRERQAD PGAQVCAAAP AIGTGRIGGL AEEEASAGPR GARPASPQAQ PCLWPDPPHF LYWSGFLGFS ELGF
Genular Protein ID: 2429421024
Symbol: A0A087WXV5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
Sequence Information:
- Length: 457
- Mass: 47225
- Checksum: AC4241091EEFCF9C
- Sequence:
MKFTLGLGSR AWRVSWEGAA AAAAGPGAGG SALRCRAQRV SSPRLGRRGS RLSGALPLCL SRGGGGAQAL PDCAGPSPGH PGHPGARQLA GPLAMEQTYG EVNQLGGVFV NGRPLPNAIR LRIVELAQLG IRPCDISRQL RVSHGCVSKI LARYNETGSI LPGAIGGSKP RVTTPNVVKH IRDYKQGDPG IFAWEIRDRL LADGVCDKYN VPSVSSISRI LRNKIGSLAQ PGPYEASKQP PSQPTLPYNH IYQYPYPSPV SPTGAKMGSH PGVPGTAGHV SIPRSWPSAH SVSNILGIRT FMEQTGALAG SEGTAYSPKM EDWAGVNRTA FPATPAVNGL EKPALEADIK YTQSASTLSA VGGFLPACAY PASNQHGVYS APGGGYLAPG PPWPPAQGPP LAPPGAGVAV HGGELAAAMT FKHPSREVAD RKPPSSGSKA PDALSSLHGL PIPASTS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.