Details for: CDK16
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 135.2661
Cell Significance Index: -21.0400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 89.5746
Cell Significance Index: -22.7200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 54.4138
Cell Significance Index: -25.6900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 53.1560
Cell Significance Index: -21.6000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 48.6795
Cell Significance Index: -25.0400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 22.6763
Cell Significance Index: -21.6500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 19.0599
Cell Significance Index: -23.5000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.5040
Cell Significance Index: -25.4600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 6.2772
Cell Significance Index: -19.2800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.1074
Cell Significance Index: -24.1000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.5365
Cell Significance Index: -7.7400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.6892
Cell Significance Index: 274.7300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4768
Cell Significance Index: 1333.4800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.1347
Cell Significance Index: 30.8900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.0888
Cell Significance Index: 56.5600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0560
Cell Significance Index: 114.8700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.0112
Cell Significance Index: 29.1400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.7834
Cell Significance Index: 35.5100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.6990
Cell Significance Index: 381.7200 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.5944
Cell Significance Index: 1.3400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5711
Cell Significance Index: 70.2200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5700
Cell Significance Index: 11.9300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5610
Cell Significance Index: 12.1600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5487
Cell Significance Index: 37.9500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.5397
Cell Significance Index: 28.1100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5067
Cell Significance Index: 101.6400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5059
Cell Significance Index: 50.0400 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.5036
Cell Significance Index: 6.4500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.4398
Cell Significance Index: 6.5900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4300
Cell Significance Index: 77.5200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4194
Cell Significance Index: 19.7100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3803
Cell Significance Index: 52.2200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3623
Cell Significance Index: 16.8900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.3550
Cell Significance Index: 70.4600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3228
Cell Significance Index: 9.0200 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3206
Cell Significance Index: 41.4300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3136
Cell Significance Index: 138.6700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2983
Cell Significance Index: 22.2300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2967
Cell Significance Index: 19.1400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2822
Cell Significance Index: 7.4200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2754
Cell Significance Index: 47.0300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2280
Cell Significance Index: 11.9700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2269
Cell Significance Index: 6.0800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2218
Cell Significance Index: 26.1600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.2143
Cell Significance Index: 2.3300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1963
Cell Significance Index: 37.3600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1912
Cell Significance Index: 68.5700 - Cell Name: peg cell (CL4033014)
Fold Change: 0.1721
Cell Significance Index: 3.9800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1586
Cell Significance Index: 3.9700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1338
Cell Significance Index: 2.8500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1192
Cell Significance Index: 7.5100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1171
Cell Significance Index: 3.7500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1106
Cell Significance Index: 14.1800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1099
Cell Significance Index: 3.8600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0916
Cell Significance Index: 6.4800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.0858
Cell Significance Index: 0.7900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0837
Cell Significance Index: 2.4000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0818
Cell Significance Index: 56.5900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.0518
Cell Significance Index: 1.8000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0109
Cell Significance Index: 0.2900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0050
Cell Significance Index: 3.6600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0005
Cell Significance Index: -0.3500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0025
Cell Significance Index: -4.6400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0076
Cell Significance Index: -4.7600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0116
Cell Significance Index: -21.3700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0123
Cell Significance Index: -9.0900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0136
Cell Significance Index: -20.8600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0178
Cell Significance Index: -24.1700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0189
Cell Significance Index: -12.0000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0220
Cell Significance Index: -2.2500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0331
Cell Significance Index: -18.6400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0357
Cell Significance Index: -0.3700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0386
Cell Significance Index: -17.5400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0496
Cell Significance Index: -3.0500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0505
Cell Significance Index: -0.8700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0562
Cell Significance Index: -4.3200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0565
Cell Significance Index: -8.2100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0632
Cell Significance Index: -13.3200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0657
Cell Significance Index: -7.5300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0839
Cell Significance Index: -5.6400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0864
Cell Significance Index: -24.8500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0938
Cell Significance Index: -10.9400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1107
Cell Significance Index: -1.5100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1131
Cell Significance Index: -12.9100 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.1312
Cell Significance Index: -1.0700 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.1490
Cell Significance Index: -2.0900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1750
Cell Significance Index: -9.8200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1849
Cell Significance Index: -2.1000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1963
Cell Significance Index: -5.2500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2235
Cell Significance Index: -23.2700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2236
Cell Significance Index: -17.7100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2241
Cell Significance Index: -3.7500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2889
Cell Significance Index: -17.7100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3809
Cell Significance Index: -16.8500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3820
Cell Significance Index: -10.9000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3888
Cell Significance Index: -11.4200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.4101
Cell Significance Index: -7.5800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4619
Cell Significance Index: -11.8000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4637
Cell Significance Index: -17.5600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4667
Cell Significance Index: -12.0000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2031625513
Symbol: CDK16_HUMAN
Name: Cyclin-dependent kinase 16
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1639063
Title: A family of human cdc2-related protein kinases.
PubMed ID: 1639063
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22796189
Title: Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.
PubMed ID: 22796189
PubMed ID: 22798068
Title: Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic beta-cells.
PubMed ID: 22798068
PubMed ID: 22184064
Title: Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.
PubMed ID: 22184064
DOI: 10.1128/mcb.06261-11
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 496
- Mass: 55716
- Checksum: 9A5DDD34A5E5CBBB
- Sequence:
MDRMKKIKRQ LSMTLRGGRG IDKTNGAPEQ IGLDESGGGG GSDPGEAPTR AAPGELRSAR GPLSSAPEIV HEDLKMGSDG ESDQASATSS DEVQSPVRVR MRNHPPRKIS TEDINKRLSL PADIRLPEGY LEKLTLNSPI FDKPLSRRLR RVSLSEIGFG KLETYIKLDK LGEGTYATVY KGKSKLTDNL VALKEIRLEH EEGAPCTAIR EVSLLKDLKH ANIVTLHDII HTEKSLTLVF EYLDKDLKQY LDDCGNIINM HNVKLFLFQL LRGLAYCHRQ KVLHRDLKPQ NLLINERGEL KLADFGLARA KSIPTKTYSN EVVTLWYRPP DILLGSTDYS TQIDMWGVGC IFYEMATGRP LFPGSTVEEQ LHFIFRILGT PTEETWPGIL SNEEFKTYNY PKYRAEALLS HAPRLDSDGA DLLTKLLQFE GRNRISAEDA MKHPFFLSLG ERIHKLPDTT SIFALKEIQL QKEASLRSSS MPDSGRPAFR VVDTEF
Genular Protein ID: 1681080765
Symbol: Q9BRL4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 448
- Mass: 51091
- Checksum: 604E761BBD217D24
- Sequence:
MDRMKKIKRQ LSMTLSSAPE IVHEDLKMGS DGESDQASAT SSDEVQSPVR VRMRNHPPRK ISTEDINKRL SLPADIRLPE GYLEKLTLNS PIFDKPLSRR LRRVSLSEIG FGKLETYIKL DKLGEGTYAT VYKGKSKLTD NLVALKEIRL EHEEGAPCTA IREVSLLKDL KHANIVTLHD IIHTEKSLTL VFEYLDKDLK QYLDDCGNII NMHNVKLFLF QLLRGLAYCH RQKVLHRDLK PQNLLINERG ELKLADFGLA RAKSIPTKTY SNEVVTLWYR PPDILLGSTD YSTQIDMWGV GCIFYEMATG RPLFPGSTVE EQLHFIFRIL GTPTEETWPG ILSNEEFKTY NYPKYRAEAL LSHAPRLDSD GADLLTKLLQ FEGRNRISAE DAMKHPFFLS LGERIHKLPD TTSIFALKEI QLQKEASLRS SSMPDSGRPA FRVVDTEF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.